Functional Remediation Improves Serum BDNF and TrkB Levels in Euthymic Patients with Bipolar Disorder: A Randomized Trial Study by Li R, Li J, Ji SS, Li D, Chu L, Zhang J, Sun X, Luo X, Zhang Y

“…Ru Li,1,* Jiaxin Li,1,* Shiyi Suzy Ji,2 Dazhi Li,1 Lijun Chu,1 Jian Zhang,1 Xia Sun,1 Xingguang Luo,3 Yong Zhang1 1Unit of Bipolar Disorder, Tianjin Anding Hospital, Tianjin, People’s Republic of China; 2Department of Counseling and Clinical Psychology, Teachers College, Columbia University, NY, New York, USA; 3Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA*These authors contributed equally to this workCorrespondence: Yong Zhang, Unit of Bipolar Disorder, Tianjin Anding Hospital, 13 Liulin Road, Hexi District, Tianjin, 300222, People’s Republic of China, Tel/Fax +86 22 8818 8258, Email zhangyong@tjmhc.comPurpose: We aimed to verify the impact of functional remediation (FR) on serum brain-derived neurotrophic factor (BDNF) and tyrosine kinase receptor B (TrkB) levels, to explore the biomechanism of FR intervention in patients with euthymic bipolar disorder (BD).Patients and Methods: This is a randomized controlled, 12-week intervention study with participants randomized into the FR group (n=39) and the treatment as usual group (TAU, n=42) at the 1∶1 ratio. 17-Hamilton Depression Rating Scale-17 (HDRS-17), Young Mania Rating Scale (YMRS), and Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Consensus Cognitive Battery (MCCB) were used to assess affective symptoms and cognitive functioning both at baseline and week 12, respectively. …”
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Biomass allocation and root topology alteration of an introduced amphibious plant in response to cultural eutrophication by Xiaolong Huang, Yu Zhao, Hai Xu, Chunyu Yin, Ruijie Shen, Baohua Guan, Zhigang Mao, Hu He, Jinlei Yu, Kuanyi Li

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Solid Self-Microemulsifying Drug Delivery System for Improved Oral Bioavailability of Relugolix: Preparation and Evaluation by Li ZL, Deng GX, Fang CZ, Zhao YQ, Yuan J, Chen L, Zhong HJ, Guo F

“…Zi-Lin Li,1,* Guo-Xing Deng,1,* Chuan-Zhou Fang,1,* Yue-Qi Zhao,1 Jing Yuan,2 Liang Chen,3 Hai-Jun Zhong,1 Feng Guo1 1School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People’s Republic of China; 2College of Basic Medicine and Forensic Medicine, Henan University of Science and Technology, Luoyang, 471000, People’s Republic of China; 3Jiangxi Prozin Pharmaceutical Co., LTD, Jian, 343100, People’s Republic of China*These authors contributed equally to this workCorrespondence: Feng Guo; Hai-JunZhong, School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People’s Republic of China, Tel +86 0791 86361839, Email fengguo@ncu.edu.cn; zhonghj@ncu.edu.cnPurpose: To improve the oral absorption of relugolix (RLGL), which has low oral bioavailability due to its low solubility and being a substrate of P-glycoprotein (P-gp). …”
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Identification of Potential Diagnostic Biomarkers of Carotid Atherosclerosis in Obese Populations by Wu X, Pan J, Pan X, Kang J, Ren J, Huang Y, Gong L, Li Y

“…Xize Wu,1,* Jiaxiang Pan,2,* Xue Pan,1,3,* Jian Kang,1 Jiaqi Ren,1 Yuxi Huang,1 Lihong Gong,2,4 Yue Li2,4 1Graduate School, Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, 110847, People’s Republic of China; 2Department of Cardiology, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, 110032, People’s Republic of China; 3College of Traditional Chinese Medicine, Dazhou Vocational College of Chinese Medicine, Dazhou, Sichuan, 635000, People’s Republic of China; 4Liaoning Provincial Key Laboratory of TCM Geriatric Cardio-Cerebrovascular Diseases, Shenyang, Liaoning, 110032, People’s Republic of China*These authors contributed equally to this workCorrespondence: Lihong Gong; Yue Li, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, No. 33, Beiling Street, Huanggu District, Shenyang, Liaoning, 110032, People’s Republic of China, Tel +86 024-82961105, Email Linda1795@sina.com; med_liyue@163.comObjective: This study aimed to investigate the potential mechanisms and biomarkers between Obesity (OB) and carotid atherosclerosis (CAS).Methods: The GSE12828, GSE125771, GSE43292, and GSE100927 datasets were combined and normalized to obtain CAS-related differentially expressed genes (DEGs), and OB-related DEGs were obtained from the GSE151839 dataset and the GeneCards database. …”
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Does completion of radical hysterectomy improve oncological outcomes of women with clinical early-stage cervical cancer and intraoperative detection of nodal involvement?: protocol... by Hui Xu, Qing Liu, Yu Xu, Yi Du, Ai Zheng, Cui Hu, Ya Jia, Qianwen Zhang, Yue-Dong He, Shuang-Shuang Cui, Yong Tian, Lin Ran, Fengmei Ke

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A novel gene signature for predicting outcome in colorectal cancer patients based on tumor cell-endothelial cell interaction via single-cell sequencing and machine learning by Lina Pang, Qingxia Sun, Wenyue Wang, Mingjie Song, Ying Wu, Xin Shi, Xiaonan Shi

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The Role of Thickening Agent Proportions in Optimizing Nanoemulsion Gel for Dermatophytosis Treatment by Zhang X, Wu CC, Jiang H, Zhao JF, Pan ZJ, Zheng Y

“…Xiao Zhang,1,* Chen-Chen Wu,1 Hua Jiang,2 Jia-Fu Zhao,1,3 Zhong-Jian Pan,1 Yin Zheng1,3,* 1College of Animal Science, Guizhou University, Guiyang, Guizhou, People’s Republic of China; 2College of Veterinary Medicine, Gansu Agriculture University, Lanzhou, Gansu, People’s Republic of China; 3Key Laboratory of Animal Genetics, Breeding and Reproduction in The Plateau Mountainous Region, Ministry of Education, Guizhou University, Guiyang, Guizhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yin Zheng, College of Animal Science, Guizhou University, Mingyi Building (Teaching and Research Center), Room 428, West Campus of Guizhou University, Huaxi District, Guiyang City, Guizhou Province, 550025, People’s Republic of China, Email yzheng@gzu.edu.cnBackground: Adjusting thickening agent proportions in nanoemulsion gel (NG) balances its transdermal and topical delivery properties, making it more effective for dermatophytosis treatment.Methods: Carbomer 940 and α-pinene were used as model thickening agent and antifungal, respectively. …”
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Comprehensive Analysis of Programmed Cell Death-Related Genes in Diagnosis and Synovitis During Osteoarthritis Development: Based on Bulk and Single-Cell RNA Sequencing Data by Zhou J, Jiao S, Huang J, Dai T, Xu Y, Xia D, Feng Z, Chen J, Li Z, Hu L, Meng Q

“…JiangFei Zhou,1,* SongSong Jiao,1,* Jian Huang,2,* TianMing Dai,3,* YangYang Xu,1,* Dong Xia,4,* ZhenCheng Feng,1 JunJie Chen,1 ZhiWu Li,5 LiQiong Hu,4 QingQi Meng1,3 1Department of Orthopedics, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, 510220, People’s Republic of China; 2Qingdao Medical College, Qingdao University, Qingdao, 266071, People’s Republic of China; 3Guangzhou Institute of Traumatic Surgery, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, 510220, People’s Republic of China; 4Critical Care Medicine Department, Guangzhou Red Cross Hospital of Jinan University, Guangzhou, 510220, People’s Republic of China; 5Department of Orthopedics, the 2nd People’s Hospital of Bijie, Guizhou, 551700, People’s Republic of China*These authors contributed equally to this workCorrespondence: LiQiong Hu; QingQi Meng, Email 13929526981@163.com; mengqingqi@jnu.edu.cnBackground: Synovitis is one of the key pathological feature driving osteoarthritis (OA) development. …”
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“Restoration of the Past Scenery-Realm”: A Research on the Scenery-Realm Restoration of Jiang’s Fu Garden During Qing Dynasty in the Historical Revolution of the Humble Administrat... by Qian BIAN

“…In terms of realm experience, the research analyzes the generation of typical comprehensive experience and emotional activities in the garden from the perspectives of “Dong You Jian Jing Can” (roaming in motion and meditation in stillness) and “Ya Ji Yu Yuan Ju” (elegant gathering and garden dwelling), pointing out that the former, in short-term composite perceptions, is more likely to form differentiated results due to changes in mood, season, and combinations of dynamic and static appreciation, while the latter, through long-term interactive attachment and more nuanced examinations over time, can make the emotional sustenance of guests in the garden more genuine and varied. 2) In response to the question of what qualified the garden as a restoration of the past scenery-realm, the focus is on the “Yuanxiang Hall” area as a clue to explore the value orientation of the Fu Garden’s restoration. …”
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Quantitative Analysis and Comparison of Flavonoids in Lotus Plumules of Four Representative Lotus Cultivars by Ting Liu, Mingzhi Zhu, Chunyun Zhang, Mingquan Guo

“…Xianglian from Xiangtan (1173.07 mg/100 g), and cv. Jianlian from Jianning (930.08 mg/100 g). However, similar percentages of flavonoid C-glycosides in the total flavonoids were found for four cultivars, which were 80.83% for cv. …”
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Research Progress of SGLT2 Inhibitors in Cancer Treatment by Miao X, Zhang J, Huang W, Wang Y, Jin A, Cao J, Zhao Z

“…Xiaoyong Miao,1,* Jianing Zhang,2,* Weiyan Huang,2,* Yifei Wang,1 Aixia Jin,1 Jianping Cao,1 Zhenzhen Zhao3 1Department of Anesthesiology, Naval Medical Center, Naval Medical University, Shanghai, People’s Republic of China; 2Student Brigade, Changhai Hospital, Naval Medical University, Shanghai, People’s Republic of China; 3Department of Anesthesiology, Changhai Hospital, Naval Medical University, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Zhenzhen Zhao, Department of Anesthesiology, Changhai Hospital, Naval Medical University, Shanghai, 200433, People’s Republic of China, Email zpluto@163.com Jianping Cao, Department of Anesthesiology, Naval Medical Center, Naval Medical University, Shanghai, 200050, People’s Republic of China, Email cjpcl221019@sina.comAbstract: Sodium glucose co-transporter 2 (SGLT2) inhibitors represent a novel class of hypoglycemic drugs that have emerged in recent years. …”
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Keratosis Follicularis Squamosa in Unilateral Buttock: A Case Report and Review of Literature in China by Jianing Wang, Zhimin Duan, Haoxiang Xu, Rong Zeng, Min Li

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Effect of extended care APPs based on the transtheoretical model of behavior change on self-management abilities in young and middle-aged patients with newly diagnosed diabetes mel... by YANG Yongfang (杨永芳), YAN Wei (严娓)

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Three Solutions for Fourth-Order Impulsive Differential Inclusions via Nonsmooth Critical Point Theory by Dongdong Gao, Jianli Li

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Genetic Variation for Wild Populations of the Rare and Endangered Plant <i>Glyptostrobus pensilis</i> Based on Double-Digest Restriction Site-Associated DNA Sequencing by Yongrong Huang, Yu Li, Xiaojie Hong, Suzhen Luo, Dedan Cai, Xiangxi Xiao, Yunpeng Huang, Yushan Zheng

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Boundary Robust Adaptive Control of a Flexible Timoshenko Manipulator by Jianing Zhang, Ge Ma, Zhifu Li

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Application of Intraoperative Ultrasound in Robot-assisted Thrombectomy for Renal Cell Carcinoma by Zhu Jianing, Li Nan, Luo Yukun, Li Qiuyang

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Error Modeling, Calibration, and Nonlinear Interpolation Compensation Method of Ring Laser Gyroscope Inertial Navigation System by Jianli Li, Yanhai Ma, Chen Xiyuan

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Research on the Application of Variational Autoencoder in Image Generation by Liu Jianing

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A Study on Coastline Extraction and Its Trend Based on Remote Sensing Image Data Mining by Yun Zhang, Xueming Li, Jianli Zhang, Derui Song

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