The role of natural products targeting macrophage polarization in sepsis-induced lung injury by Yake Li, Sinan Ai, Yuan Li, Wangyu Ye, Rui Li, Xiaolong Xu, Qingquan Liu

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Lecanemab’s Path Forward: Navigating the Future of Alzheimer’s Treatment in Europe Amidst the EMA's Rejection by Alessandro Martorana, Chiara Giuseppina Bonomi, Martina Gaia Di Donna, Caterina Motta

“…Abstract Lecanemab (Leqembi©, Biogen), a humanized anti-amyloid-beta monoclonal antibody, has been approved for early-stage Alzheimer’s disease (AD) in several countries, including the US and Japan. However, the European Medicines Agency (EMA) recently issued a negative opinion on its marketing authorization, reflecting concerns over the clinical value and manageability of anti-amyloid treatments. …”
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The Influence of Electrolytic Concentration on the Electrochemical Deposition of Calcium Phosphate Coating on a Direct Laser Metal Forming Surface by Qianyue Sun, Yuhui Yang, Wenjing Luo, Jinghui Zhao, Yanmin Zhou

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Association of nonalcoholic fatty liver disease and growth hormone deficiency: a systematic review and meta-analysis by Tingting Kong, Yunpeng Gu, Lei Sun, Run Zhou, Jie Li, Junping Shi

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Comprehensive Ultrasound Diagnosis of Sigmoid Diverticulitis by A. I. Кoushnerou, I. A. Hadji-Ismail, A. V. Vorobei, S. I. Rudenka

“…We used the HD15 (Philips, the Netherlands), HS 60 (Samsung, South Korea) and Hi Vision Preirus (Hitachi, Japan) ultrasound instruments equipped with convex and intracavitary microconvex 2–12 MHz linear transducers. …”
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Effect of Coexisting TiO2 Powder on Ionic Conduction of Highly Concentrated LiTFSA Aqueous Electrolyte (20.5 mol kg−1) by Jingchao XU, Hideshi MAKI, Hiro MINAMIMOTO, Minoru MIZUHATA

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Extending TextAE for annotation of non-contiguous entities by Jake Lever, Russ Altman, Jin-Dong Kim

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Impact of Baseline Central Retinal Thickness on Outcomes in the VIVID-DME and VISTA-DME Studies by Edoardo Midena, Mark Gillies, Todd A. Katz, Carola Metzig, Chengxing Lu, Yuichiro Ogura

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An innovative framework for incorporating iPhone LiDAR point cloud in digitized documentation of road operations by Srikulnath Nilnoree, Tsukasa Mizutani

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ZIF-8-Embedded Cation-Exchange Membranes with Improved Monovalent Ion Selectivity for Capacitive Deionization by Eui-Gyu Han, Ji-Hyeon Lee, Moon-Sung Kang

“…MCDI tests using the prepared CEMs showed a Na⁺ ion removal rate exceeding 99% in Na⁺/Mg²⁺ and Na⁺/Ca²⁺ mixed feed solutions, outperforming a commercial membrane (CSE, Astom Corp., Tokyo, Japan), which achieved a removal rate of 94.1%. These findings are expected to provide valuable insights for advancing not only MCDI but also other electro-membrane processes capable of selectively separating specific ions.…”
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Glucose-Lowering Agents Developed in the Last Two Decades and Their Perioperative Implications by Basavana Goudra, Geno J. Merli, Michael Green

“…For instance, Imeglimin, a variant of metformin available in Japan and India, Icodec, a once-weekly basal insulin formulation, and IcoSema, a once-weekly combination of Icodec plus semaglutide, are all being explored, although in their early stages or facing approval challenges.…”
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Research progress of breast cancer surgery during 2010–2024: a bibliometric analysis by Jiawei Kang, Nan Jiang, Munire Shataer, Tayier Tuersong

“…The United States, China, and Japan are the leading contributors to research output, with the United States showing the most extensive international collaboration. …”
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Budget Impact Analysis of Treatment Flow Optimization in Epilepsy Patients: Estimating Potential Impacts with Increased Referral Rate to Specialized Care by Masaki Iwasaki, Takashi Saito, Akiko Tsubota, Tatsunori Murata, Yuta Fukuoka, Kazutaka Jin

“…Direct costs of pharmacotherapies, management fees and surgeries are included in the analysis to evaluate the annual budget impact in Japan. **Results:** In the current treatment flow, the number of refractory patients treated with four drugs by non-specialized care were estimated as 8766 and yielded JPY5.8 billion annually. …”
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A Low-Complexity GA-WSF Algorithm for Narrow-Band DOA Estimation by Haihua Chen, Jialiang Hu, Hui Tian, Shibao Li, Jianhang Liu, Masakiyo Suzuki

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Small Surface Fatigue Crack Behaviors of Cr-Mo Steel AISI4137 by Seung-Hoon Nahm, Sang-Koo Jeon, Dong-Kyun Kim, Min-Soo Suh, Chang-Min Suh

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Validation of the Japanese Version of the Questionnaire for Impulsive-Compulsive Disorders in Parkinson’s Disease-Rating Scale (QUIP-RS) by Maiko Takahashi, Jinsoo Koh, Shoko Yorozu, Yoshinori Kajimoto, Yoshiaki Nakayama, Mayumi Sakata, Masaaki Yasui, Yasuhiro Hiwatani, Daniel Weintraub, Hidefumi Ito

“…We aimed to validate the Japanese version of QUIP-RS and determine the characteristics of ICBs in Japan. Methods. We translated the QUIP-RS into Japanese, back-translated it to English, and obtained confirmation from the original author that the questionnaire remained appropriate. …”
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A comprehensive review on multifunctional bioactive properties of elm oyster mushroom Hypsizygus ulmarius (Bull.) Redhead (Agaricomycetes): Current research, challenges and future... by Aditya, Neeraj, J.N. Bhatia, Ajar Nath Yadav

“…This mushroom also holds significant importance globally and is cultivated in China, Japan and other Asian nations due to its favorable growth conditions, exceptional nutritional value, and medicinal attributes. …”
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Polymers for the treatment of Alzheimer’s disease by Yunfeng Zhu, Haibin Xu, Chaoyan Yu, Wenting Jiang, Xiaowen Hou, Mingyue Ma, Ji Wu

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Long-term effects of institutional quality on financial inclusion in Asia–Pacific countries by Duc Hong Vo

“…Interestingly, this long-term effect can be established for high-income countries such as Australia and Japan but not for Singapore. In addition, in the case of middle-income countries, the long-term effect can be confirmed for countries such as Malaysia, Indonesia, and the Philippines but not for Thailand and Vietnam. …”
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Are Men Aging as Oaks and Women as Reeds? A Behavioral Hypothesis to Explain the Gender Paradox of French Centenarians by Frédéric Balard, Isabelle Beluche, Isabelle Romieu, Donald Craig Willcox, Jean-Marie Robine

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