Dupilumab-induced psoriasis in a patient with atopic dermatitis successfully treated with Upadacitinib: A case report by Katrina D Cirone, Fiona E Lovegrove

“…Upadacitinib, an oral, selective Janus kinase 1 inhibitor, approved for use in moderate-to-severe atopic dermatitis as well as psoriatic arthritis may have a potential role in psoriasis treatment. …”
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Chronic Myeloid Leukemia in a Patient Receiving Tofacitinib: A Case Report and Literature Review by Georgio Medawar, Joseph Chahrouri, Rabih Said

“…Tofacitinib is a new oral Janus kinase inhibitor that has shown promising clinical benefit in various rheumatologic diseases. …”
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La difficile construction de l’identité professionnelle des professeurs-documentalistes de l’enseignement agricole public by Jean-François Marcel, Cécile Gardiès

“…Three interconnected identity figures (Janus as a tutelary figure, Sysiphus in the background and at last the rising figure of the resilient) stand between “inherited identity”, “attributed identity” and “pursued identity” but clearly testify the tension between those three poles.…”
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BMN-like sectors in 4d N $$ \mathcal{N} $$ = 4 SYM with boundaries and interfaces by Andrea Chaney, Christoph F. Uhlemann

“…For a sample of theories including the Janus interface, D3/D5 BCFTs and BCFTs with 3d SCFTs on the boundary, we determine the spectra of nearby operators and discuss the field theory realization of the seed operators. …”
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Life-Threatening Hypertriglyceridemia in a Patient on Ruxolitinib and Sirolimus for Chronic Graft-versus-Host Disease by Allison P. Watson, Claudio G. Brunstein, Shernan G. Holtan

“…Ruxolitinib is an oral selective Janus-associated kinase 1 (JAK1) and JAK2 inhibitor that was initially approved by the FDA in 2014 for treatment of myelofibrosis. …”
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The Anticancer Perspective of Tangeretin: A Small Review by Yuan Xu, Xi Yan, Junpeng Zhuang, Haijun Hao

“…Tangeretin can inhibit the growth, proliferation, and metastasis of cancer cells by acting on JAK/STAT (Janus Kinase/signal transducer and activator of transcription) and caspase-3 signal transduction and by regulating the cell cycle of tumor cells. …”
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Reactivation of Pulmonary Tuberculosis following Treatment of Myelofibrosis with Ruxolitinib by Maheen Z. Abidi, Javeria Haque, Parvathi Varma, Horatiu Olteanu, Guru Subramanian Guru Murthy, Binod Dhakal, Parameswaran Hari

“…It causes inhibition of the Janus kinase (JAK) signal transducer and activation of transcription (STAT) pathway, which plays a key role in the underlying pathophysiology of myeloproliferative diseases. …”
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Habiter la mémoire à la frontière de l’oubli : la maison comme seuil by Joana Duarte Bernardes

“…Always beginning and end, the threshold surpasses the duplicity of Janus by confronting the two faces, as if identity could not see without alterity. …”
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Atypical Myocardial Infarction with Apical Thrombus and Systemic Embolism: A Rare Presentation of Likely JAK2 V617F-Positive Myeloproliferative Neoplasm by Muhammed Atere, Rana Al-Zakhari, Jennifer Collins, Francesco Rotatori, Lloyd Muzangwa

“…A few types of myeloproliferative neoplasms may be significant for Janus-associated kinase 2 mutation, JAK2 V617F, including polycythemia vera, essential thrombocythemia, and primary myelofibrosis. …”
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Jews, Rights, and Belonging in Tunisia: Léon Elmilik, 1861-1881 by Jessica M. Marglin

“…Rather than presume that Elmilik was a janus-faced opportunist, I argue that his different, at times opposed engagements were representative of the multiple repositories in which Jews located their rights. …”
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The Potential of Food Protein-Derived Bioactive Peptides against Chronic Intestinal Inflammation by Wanying Zhu, Liying Ren, Li Zhang, Qinqin Qiao, Muhammad Zahid Farooq, Qingbiao Xu

“…The mechanism, pathways, and future perspectives of BAPs as the potential sources of therapeutic treatments to alleviate intestinal inflammation are provided, including nuclear factor-κB, mitogen-activated protein kinase, Janus kinase-signal transducer and activator of transcription, and peptide transporter 1 (PepT1), finding that PepT1 and gut microbiota are the promising targets for BAPs to alleviate the intestinal inflammation. …”
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Emerging therapeutics in idiopathic inflammatory myopathy by Shinji Sato

“…In recent years, new therapeutic approaches using biologics or Janus kinase inhibitors, plasma exchange therapy, and other agents have been evaluated for IIMs. …”
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JAK inhibitors: a new choice for diabetes mellitus? by Mengjun Zhou, Qi Shen, Bo Li

“…Nonreceptor-type tyrosine kinases are subdivided into Janus kinases (JAKs), focal adhesion kinases (FAKs) and tec protein tyrosine kinases (TECs). …”
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Photoinduced Synthesis of New Diisochromenochromen-4-ones and Their Antimicrobial Activities by Mohamad Yusuf, Indu Solanki, Payal Jain

“…The antibacterial and antifungal activities of the synthesized products were also evaluated against the Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus, Bacillus subtilis, and Aspergillus janus and Penicillium glabrum, respectively. Some of the tested compounds showed significant activity against the above-said microorganisms.…”
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Precision medicine using molecular-target drugs in psoriatic arthritis by Ippei Miyagawa, Yoshiya Tanaka

“…As the pathology of PsA has been clarified, molecular-targeted drugs targeting tumor necrosis factor-α, interleukin (IL)-17A, IL-17A/F, IL-17 receptor, IL-12/23(p40), IL-23p19, Cytotoxic T-lymphocyte Antigen-4 (CTLA-4), Janus kinase, and phosphodiesterase-4 have been developed and are widely used in clinical practice. …”
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Systems Biological Approaches Reveal Non-additive Responses and Multiple Crosstalk Mechanisms between TLR and GPCR Signaling by Jayalakshmi Krishnan, Sangdun Choi

“…In addition, to determine the network communications among the TLR, Janus kinase (JAK)/signal transducer and activator of transcription (STAT), and GPCR, we tested RAW 264.7 cells with KDO, interferon-β, or cAMP analog 8-Br. …”
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Identification of a Novel Primary Atopic Disorder due to STAT6 Gain-of-Function Mutations by Safa Barış, Talal A. Chatila

“…A subset of IEI, which manifests as severe allergic disorders, recently termed "primary atopic disorders'', now encompasses over 30 monogenic defects. Notably, the Janus kinase (JAK)-signal transducer and activator of transcription 6 (STAT6) signaling pathway plays a pivotal role in mediating allergic responses and developing primary atopic disorders. …”
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Fine-tuning SLE treatment: the potential of selective TYK2 inhibition by Yoshiya Tanaka, Shingo Nakayamada, Yurie Satoh-Kanda

“…Many cytokines transmit signals via the Janus-activated kinase (JAK)-STAT pathway, but there is no one-to-one correspondence between cytokine receptors and JAK/TYK2. …”
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Case report: Exploring efficacy of tofacitinib in modulating interferon response in five case of anti-MDA5+ dermatomyositis with interstitial lung disease by Jie Zhao, Yan Bao, Ying Gao, Keliang Xie

“…In an attempt to stem the relentless progression, tofacitinib, a Janus kinase (JAK) inhibitor, was applied into her treatment regimen. …”
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Treatment of Acute Graft-versus-Host Disease in Liver Transplant Recipients by Edward Kim, Alina Adeel, Adel Bozorgzadeh, Shinya Amano, Curtis T. Barry, Jennifer S. Daly, Deepika Devuni, Zendee Elaba, Laura Houk, Paulo N. Martins, Babak Movahedi, Muthalagu Ramanathan, Nicole M. Theodoropoulos

“…We report on two patients who developed aGvHD after liver transplantation who were treated with ruxolitinib, a novel Janus kinase 1/2 (JAK) inhibitor that has been shown to improve outcomes in steroid refractory cases of aGvHD after allogenic hematopoietic stem cell transplantation. …”
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