Biomimetic polydopamine loaded with janus kinase inhibitor for synergistic vitiligo therapy via hydrogel microneedles by Chunying Li, Wenwen Wang, Junyi Shao, Sen Zhou, Xiaolin Ji, Youxia Xi, Qiuyang Xu, Yuhan Huang, Jingle Wang, Yilin Wan, Zhiming Li

“…Additionally, the accumulated CD8+ T cells release interferon-γ (IFN-γ) to activate janus kinase-signal transducer and activator of transcription (JAK-STAT) pathway in keratinocytes. …”
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RETRACTED: Preparation and Analysis of Structured Color Janus Droplets Based on Microfluidic 3D Droplet Printing by Chuang Wu, Hanqi Jia, Haithm Yahya Mohammed Almuaalemi, A. S. M. Muhtasim Fuad Sohan, Binfeng Yin

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Weight gain secondary to the use of oral Janus kinase inhibitors: A systematic review and meta-analysis by Grace Xiong, BHSc, Eric Yu, Martin Heung, Jaehyeong Yang, BSc, Megan Lowe, MPH, Mohannad Abu-Hilal, MD

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Surface enzyme-polymerization endows Janus hydrogel tough adhesion and regenerative repair in penetrating orocutaneous fistulas by Ye Ju, Chunyue Ma, Ling Ding, Mingyue Shi, Xia Wang, Dongbei Wu, Qing Wu, Xingjun Qin, Qigang Wang

“…Abstract Penetrating orocutaneous or oropharyngeal fistulas (POFs), severe complications following unsuccessful oral or oropharyngeal reconstruction, remain complex clinical challenges due to lack of supportive tissue, contamination with saliva and chewed food, and dynamic oral environment. Here, we present a Janus hydrogel adhesive (JHA) with asymmetric functions on opposite sides fabricated via a facile surface enzyme-initiated polymerization (SEIP) approach, which self-entraps surface water and blood within an in-situ formed hydrogel layer (RL) to effectively bridge biological tissues with a supporting hydrogel (SL), achieving superior wet-adhesion and seamless wound plugging. …”
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Social-Ecologic Oriented Curricula in Engineering Education: “Leonardo’s Oath” as an Answer to Janus-Headedness in Engineering Work by R. Dreher, V. V. Kondratyev, M. N. Kuznetsova

“…This leads to the ethical dilemma of engineering work: when creating something new, social and environmental problems usually arise. This explains the “Janus-headedness” of the engineering profession: although the original intention is to do good, however, there are negative consequences that must be mitigated through new technical solutions that have the effect of creating improvements. …”
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Cardiovascular safety of Janus kinase inhibitors in inflammatory bowel disease: a systematic review and network meta-analysis by Huibin Yang, Ting An, Yuxuan Zhao, Xiaojing Shi, Bangmao Wang, Qingyu Zhang

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Interpretable machine learning for stability and electronic structure prediction of Janus III–VI van der Waals heterostructures by Yudong Shi, Yinggan Zhang, Jiansen Wen, Zhou Cui, Jianhui Chen, Xiaochun Huang, Cuilian Wen, Baisheng Sa, Zhimei Sun

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The Janus Face of Lipids in Human Breast Cancer: How Polyunsaturated Fatty Acids Affect Tumor Cell Hallmarks by Benoît Chénais, Vincent Blanckaert

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Efficacy and safety of Janus kinase inhibitors in the treatment of psoriasis and psoriatic arthritis: An analysis of evidence from 2014 to 2022 by Jiao Wang, Tian Ma, Xiaoying Sun, Liu Liu, Seokgyeong Hong, Huijung Cha, Miao Zhang, Jiale Chen, Naixuan Lin, Bin Li, Xin Li

Subjects: “…Janus kinase (JAK) inhibitors…”
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Synthesis and performance analysis of novel SiO2 Janus nanoparticles for enhancing gas foam injection in oil reservoirs by Amir Hossein Saeedi Dehaghani, Reza Gharibshahi, Mohammad Mohammadi

Subjects: “…Janus nanoparticles…”
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Core-shell or Janus-like Fe0.5Ni0.5 nanostructures: A theoretical and experimental study by J. Rojas-Nunez, R.M. Freire, A.L. Elias, K. Fujisawa, L. Troncoso, J.C. Denardin, N. Plaza-Alcafuz, S.E. Baltazar

“…Considering these results, the synthesis of the FeNi bimetallic nanoparticles was carried out, and core-shell and Janus-like morphologies were expected to be seen. …”
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Redefining the greenness of quantitative analytical methods for drugs: A case study of a multipurpose novel janus kinase inhibitor by Sagar Suman Panda

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Exogenous Janus Kinase 617 Codon Influences Small Noncoding RNAs and Gene Expression in Ba/F3 Cells by Yi-Yang Chen, Ying-Hsuan Wang, Chih-Cheng Chen, Cih-En Huang, Chia-Chen Hsu, Shu-Huei Hsiao, Yu-Wei Leu

“…More than 50%–90% of MPN patients had a dominant negative valine (V) to phenylalanine (F) mutation at the Janus kinase 617 codon (JAK2V617F) within the Janus kinase (JAK)-signal transducer and activator of transcription (STAT) signaling pathway; however, this mutation was also found in a high percentage of the general population, its penetrance varied, and its onset was shown to be polygenic. …”
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Role of Janus Kinase inhibitors in the management of pulmonary involvement due to Long COVID-19 disease: A case control study by Pawan Kumar Singh, Vinod Kumar Sharma, Lokesh Kumar Lalwani, Dhruva Chaudhry, Manjunath B. Govindagoudar, Chaudhari Pramod Sriram, Aman Ahuja

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Selective Immunomodulation of Inflammatory Pathways in Keratinocytes by the Janus Kinase (JAK) Inhibitor Tofacitinib: Implications for the Employment of JAK-Targeting Drugs in Psoriasis by Martina Morelli, Claudia Scarponi, Laura Mercurio, Francesco Facchiano, Sabatino Pallotta, Stefania Madonna, Giampiero Girolomoni, Cristina Albanesi

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Cumulative incidence and risk of infection in patients with rheumatoid arthritis treated with janus kinase inhibitors: A systematic review and meta-analysis. by Konstantinos Ouranos, Diana V Avila, Evangelia K Mylona, Athanasios Vassilopoulos, Stephanos Vassilopoulos, Fadi Shehadeh, Eleftherios Mylonakis

“…The goal of our study was to calculate the pooled cumulative incidence and risk of infection in patients with RA treated with Janus kinase inhibitors (JAKi). The PubMed and EMBASE databases were queried for randomized controlled trials comparing patients with RA treated with JAKi (upadacitinib, baricitinib, tofacitinib, peficitinib, or filgotinib), defined as the treatment group, compared with control subjects, defined as participants receiving placebo or treatment regimen that was similar to that of participants in the treatment group, with the exception of JAKi. …”
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Janus kinase inhibitors in rheumatoid arthritis-associated interstitial lung disease: where do we stand and what may be the future? by Beatrice Maranini, Roberta Foti, Moustapha Taha, Veronica Venturelli, Andrea Lo Monaco, Marcello Govoni

“…Over the past few years, Janus kinase inhibitors (JAKis) have been reported to have promising efficacy in the treatment of active RA, but recent concerns have been raised about their safety profile, namely malignancy and cardiovascular disease, limiting their use to certain patient categories. …”
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Small molecules in idiopathic inflammatory myopathies: a systematic review and a multicenter case series about Janus kinase inhibitors and apremilast by Chiara Rizzo, Silvia Grazzini, Edoardo Conticini, Hector Chinoy, Roberto D’Alessandro, Federica Camarda, Luca Cantarini, Bruno Frediani, Giuliana Guggino, Lidia La Barbera

“…We report our experience with Janus kinase inhibitors (JAKi) in these conditions and review the current evidence for the use of small molecules in real-life clinical practice. …”
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Multifunctional Janus-Structured Polytetrafluoroethylene-Carbon Nanotube-Fe3O4/MXene Membranes for Enhanced EMI Shielding and Thermal Management by Runze Shao, Guilong Wang, Jialong Chai, Jun Lin, Guoqun Zhao, Zhihui Zeng, Guizhen Wang

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Evaluation of Real-World Evidence to Assess Effectiveness Outcomes of Janus Kinase Inhibitors for Rheumatoid Arthritis: A Systematic Review of US Studies by Gandy C, Bazzazzadehgan S, Bruera S, Huang Y

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