Improved Risk Prediction of Acute Myocardial Infarction in Patients With Stable Coronary Artery Disease Using an Amino Acid-Assisted Model by Yi-Jing Zhao, Yong Li, Feng-Xiang Wang, Hao Lv, Yaoyao Qu, Lian-Wen Qi, Pingxi Xiao

“…This methodology incorporated 13C isotope-labeled internal standards for precise quantification of 27 amino acids. …”
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On a data-driven mathematical model for prostate cancer bone metastasis by Zholaman Bektemessov, Laurence Cherfils, Cyrille Allery, Julien Berger, Elisa Serafini, Eleonora Dondossola, Stefano Casarin

“…While treatment with the radioactive isotope radium-223 ($ ^{223} $Ra) has shown promising results, there remains room for therapy optimization. …”
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Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament by Emmajay Sutherland, Christopher J. Harding, Tancrède du Monceau de Bergendal, Gordon J. Florence, Katrin Ackermann, Bela E. Bode, Silvia Synowsky, Ramasubramanian Sundaramoorthy, Clarissa Melo Czekster

“…Pre-steady-state kinetics, a significant solvent kinetic isotope effect, and the absence of viscosity effects suggested that a step linked to FMN regeneration controlled the reaction rate. …”
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Neutrophil Gelatinase-Associated Lipocalin: A New Marker of Renal Function in C-Related End Stage Liver Disease by Omkolsoum Mohamed Alhaddad, Ayman Alsebaey, Mohamed Omar Amer, Hala Hany El-Said, Tary Abdel Hamid Salman

“…One hundred HCV related end stage liver cirrhosis patients were randomized into two groups: Group I (n=35), patients with GFR < 60 mL/m measured by isotope scanning of the kidney (Renogram), and Group II (n=65), patients with GFR ≥ 60 mL/m. …”
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Telomere Length in Elderly Caucasians Weakly Correlates with Blood Cell Counts by Ewa Gutmajster, Joanna Witecka, Magdalena Wyskida, Justyna Koscinska-Marczewska, Malgorzata Szwed, Magdalena Owczarz, Malgorzata Mossakowska, Andrzej Milewicz, Monika Puzianowska-Kuznicka, Jan Zejda, Andrzej Wiecek, Jerzy Chudek, Aleksander L. Sieron

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Organic Matter Accumulation Mechanism in the Lower Cambrian Strata from Well Luntan 1 in the Tarim Basin, NW China by Qian Deng, Haizu Zhang, Haozhe Wang, Zhiwei Wei, Bin Cheng, Shida Li, Yunpeng Wang, Oluwabamise Lekan Faboya, Zewen Liao

“…Total organic carbon (TOC) content, carbon isotope of kerogen (δ13Cker), and major and trace elements of the rocks from the Sinian Qigebulake, Cambrian Yuertusi, and Xiaoerbulake Formations in well Luntan 1 were analysed. …”
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A machine learning model using the snapshot ensemble approach for soil respiration prediction in an experimental Oak Forest by S.N. Ferdous, J.P. Ahire, R. Bergman, L. Xin, E. Blanc-Betes, Z. Zhang, J. Wang

“…Recent advances in ecosystem process models have uniquely constrained soil respiration rates, largely based on results from tracing ecosystem CO2 losses using radioisotope and stable isotope methods. However, the computational requirements of process-based models at large scales are costly, limiting their application and prediction capability. …”
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Policy relevance of IPCC reports for the Sustainable Development Goals and beyond by Prajal Pradhan, Sushobhan Joshi, Kshitij Dahal, Yaunchao Hu, Daya Raj Subedi, Muhammad Panji Islam Fajar Putra, Shrijana Vaidya, Laxmi Prasad Pant, Shobhakar Dhakal, Klaus Hubacek, Maheswar Rupakheti, Debra C. Roberts, Bart van den Hurk

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Development and Application of a LC-MS/MS Method for Simultaneous Quantification of Four First-Line Antituberculosis Drugs in Human Serum by Yunliang Zheng, Nana Xu, Xingjiang Hu, Qiao Zhang, Yanpeng Liu, Qingwei Zhao

“…MS detection was performed by a triple quadrupole tandem mass spectrometer in the multiple reaction monitoring mode with a positive electrospray ionization source. Isotope-labeled internal standard, especially rifampicin-D8, was applied to adjust for the loss during sample treatment. …”
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Black Hole Supernovae, Their Equation of State Dependence, and Ejecta Composition by Oliver Eggenberger Andersen, Evan O’Connor, Haakon Andresen, André da Silva Schneider, Sean M. Couch

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Detection Methods for Asparagine and Glutamine Contents in Fruits and Vegetables and Recommendations for Dietary Intake of Fruits and Vegetables in Patients with Urea Cycle Disorde... by YE Xinyu, LI Ziying, TANG Shujun, SUN Liping, ZHAO Yunxia, XIAO Weimin, GU Yaping, KUANG Huiying, CHEN Xin, YANG Guowu, HUANG Yali

“…The mass spectrometer was equipped with an electrospray ionization source and operated in the positive ion mode with multiple reaction monitoring (MRM), and quantification was achieved using stable isotope-labeled internal standards. The calibration curves for Asn and Gln showed a good linearity in the range of 10–1 000 ng/mL (R2 > 0.999), with limit of detection (LOD) and limit of quantification (LOQ) of 1.5 and 5.0 mg/100 g, respectively. …”
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Genesis of the Bieyesamas Monzogranite of the Altay Mountain, Xinjiang, Northwestern China, and Its Rare Metal Resource Potential by Gengbiao Qiao, Xiaoyan Chen, Wenming Li

“…According to LA-ICP-MS zircon U-Pb isotopic dating, the 206Pb/238U weighted average age of the Bieyesamas monzogranite is 451.1±5.1 Ma (MSWD=6.0), indicating the formation age of Late Ordovician. …”
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Green analysis of illicit drugs on banknote dust by Teresa Cecchi, Arianna Giuliani, Carlo Catini

“…A UHPLCHRMS system with ethanol as the organic modifier was used to develop and optimize the chromatographic method; a stable isotope labelled internal standard for each analyte was used to compensate matrix effects and possible losses. …”
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Diagenetic Modifications and Reservoir Heterogeneity Associated with Magmatic Intrusions in the Devonian Khyber Limestone, Peshawar Basin, NW Pakistan by Mumtaz M. Shah, Saifullah Afridi, Emad U. Khan, Hamad Ur Rahim, Muhammad R. Mustafa

“…II) postdates the igneous intrusions and was followed by dedolomitisation, dissolution, and cementation by meteoric calcite. Stable isotope studies likewise confirm two distinct dolomite phases. …”
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Engineering p‐Orbital States via Molecular Modules in All‐Organic Electrocatalysts toward Direct Water Oxidation by Li‐Hong Yu, Xue‐Feng Zhang, Zi‐Ming Ye, Hong‐Gang Du, Li‐Dong Wang, Ping‐Ping Xu, Yuhai Dou, Li‐Ming Cao, Chun‐Ting He

“…Operando differential electrochemical mass spectrometry (DEMS) with isotope labeling identifies the adsorbate evolution mechanism (AEM). …”
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A sterol panel for rare lipid disorders: sitosterolemia, cerebrotendinous xanthomatosis and Smith-Lemli-Opitz syndrome by Alexander Bauer Westbye, Lili L. Dizdarevic, Sandra R. Dahl, Emil Andreas Asprusten, Yngve Thomas Bliksrud, Anita Lövgren Sandblom, Ulf Diczfalusy, Per M. Thorsby, Kjetil Retterstøl

“…A simple and rapid method to extract free sterols from human serum and quantitate their concentration using isotope-dilution liquid chromatography-tandem mass spectrometry (LC-MS/MS) without derivatization was developed. …”
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Ion suppression correction and normalization for non-targeted metabolomics by Iqbal Mahmud, Bo Wei, Lucas Veillon, Lin Tan, Sara Martinez, Bao Tran, Alexander Raskind, Felice de Jong, Yiwei Liu, Jibin Ding, Yun Xiong, Wai-kin Chan, Rehan Akbani, John N. Weinstein, Chris Beecher, Philip L. Lorenzi

“…Here we report a method, the IROA TruQuant Workflow, that uses a stable isotope-labeled internal standard (IROA-IS) library plus companion algorithms to: 1) measure and correct for ion suppression, and 2) perform Dual MSTUS normalization of MS metabolomic data. …”
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PET imaging of 52Mn labeled DOTATATE and DOTAJR11 by James M. Omweri, Hailey A. Houson, Shannon E. Lynch, Volkan Tekin, Anna G. Sorace, Suzanne E. Lapi

“…Abstract Manganese-52 is gaining interest as an isotope for PET imaging due to its desirable decay and chemical properties for radiopharmaceutical development. …”
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$$\hbox {H}_2$$ -roaming dynamics in the formation of $$\hbox {H}_{3}^{+}$$ following two-photon double ionization of ethanol and aminoethanol by Aaron Ngai, Sebastian Hartweg, Jakob D. Asmussen, Björn Bastian, Matteo Bonanomi, Carlo Callegari, Miltcho Danailov, Michele di Fraia, Raimund Feifel, Sarang Dev Ganeshamandiram, Sivarama Krishnan, Aaron LaForge, Friedemann Landmesser, Ltaief Ben Ltaief, Moritz Michelbach, Nitish Pal, Oksana Plekan, Nicolas Rendler, Lorenzo Raimondi, Fabian Richter, Audrey Scognamiglio, Tobias Sixt, Richard J. Squibb, Katrin Dulitz, Frank Stienkemeier, Marcel Mudrich

“…Surprisingly, we do not observe a kinetic isotope effect in ethanol- $$\hbox {D}_6$$ , in contrast to previous experiments on methanol where such an effect was observed. …”
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A sedimentological oxymoron: highly evolved glauconite of earliest diagenetic origin by Tribovillard, Nicolas, Bout-Roumazeilles, Viviane, Guillot, François, Baudin, François, Deconinck, Jean-François, Abraham, Romain, Ventalon, Sandra

“…Carbon and oxygen stable isotope composition of the carbonate beds confirm an early diagenetic growth. …”
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