Evolution of 𝜷-Cell Replacement Therapy in Diabetes Mellitus: Islet Cell Transplantation by Cyrus Jahansouz, Cameron Jahansouz, Sean C. Kumer, Kenneth L. Brayman

“…In this paper, the historical evolution, procurement, current status, benefits, risks, and ongoing research of islet cell transplantation are explored.…”
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Bone Marrow Stem Cell as a Potential Treatment for Diabetes by Ming Li, Susumu Ikehara

“…Although pancreas or islet-cell transplantation achieves better glucose control, a major obstacle is the shortage of donor organs. …”
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Generation of Transplantable Beta Cells for Patient-Specific Cell Therapy by Xiaojie Wang, Daniel L. Metzger, Mark Meloche, Jianqiang Hao, Ziliang Ao, Garth L. Warnock

“…Islet cell transplantation offers a potential cure for type 1 diabetes, but it is challenged by insufficient donor tissue and side effects of current immunosuppressive drugs. …”
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B7-H4 Pathway in Islet Transplantation and β-Cell Replacement Therapies by Xiaojie Wang, Jianqiang Hao, Daniel L. Metzger, Ziliang Ao, Mark Meloche, C. Bruce Verchere, Lieping Chen, Dawei Ou, Alice Mui, Garth L. Warnock

“…Type 1 diabetes (T1D) is a chronic autoimmune disease and characterized by absolute insulin deficiency. β-cell replacement by islet cell transplantation has been established as a feasible treatment option for T1D. …”
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