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2821
Draft genome sequence of a co-harbouring blaNDM-5 and mcr-1.1 Escherichia coli phylogroup A isolate associated with patient colonisation in Ireland
Published 2025-01-01“…Forty-seven chromosomal VFs were identified, involved in adhesion and iron acquisition amongst other properties. Plasmid replicons associated with the spread of MDR genes such as IncHI2/HI2A were detected. wgMLST analysis showed the closest relative being a strain from the UK, exhibiting differences in the sequences of 851 genes. …”
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2822
Non-volatile voltage-controlled magnetization in single-phase multiferroic ceramics at room temperature
Published 2025-01-01“…The polarization arises from the cooperative displacement of both Fe3+ and Ti4+ relative to the oxygen sublattice in the tetragonally distorted perovskite structure, and the magnetization stems from indirect exchange magnetic interaction between adjacent iron ions. A switchable voltage-controlled magnetization was confirmed by a change of the coercive magnetic field, Hc, and remnant magnetization, Mr, in the x = 0.4 component subjected to an external electric field at room temperature and was possibly attributed to a strain-mediated ME coupling effect. …”
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2823
Polydatin protects against DSS-induced ulcerative colitis via Nrf2/Slc7a11/Gpx4-dependent inhibition of ferroptosis signalling activation
Published 2025-01-01“…Ferroptosis was determined by MDA levels, SOD levels, mitochondrial iron accumulation and ROS production. Ferroptosis-related proteins Slc7a11, Nrf2 and Gpx4 levels were measured by western blot, immunohistochemical and immunofluorescence staining.ResultsPD mitigated the DSS-induced increases in pro-inflammatory cytokines (IL-6, TNF-α, and IL-1β), alleviated colon length shortening, reduced morphological damage to the intestinal mucosa, and preserved tight junction proteins (TJ) occludin and Zonula occludens-1 (ZO-1) in both caco-2 cells and murine models of colitis. …”
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2824
CAV1 promotes epithelial-to-mesenchymal transition (EMT) and chronic renal allograft interstitial fibrosis by activating the ferroptosis pathway
Published 2025-02-01“…BackgroundChronic allograft dysfunction (CAD) stands as a critical factor that limits the long-term viability of transplanted kidneys. Ferroptosis is an iron-dependent form of programmed cell death increasingly linked to chronic fibrosis. …”
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2825
The role of PCBP1 in carbon ion-induced ferroptosis and inhibition of lung adenocarcinoma proliferation
Published 2025-01-01“…To investigate the relationship between ALOX15 expression and survival, we assessed changes in key indicators of ferroptosis (mitochondrial morphology, ROS, MDA, and divalent iron) in A549 cells after knocking down the PCBP1 gene using siRNA technology. …”
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2826
Fortifying plant fortresses: siderophores in defense against Cercospora leaf spot disease in Vigna radiata L.
Published 2025-01-01“…Siderophores, specialized iron-chelating molecules produced by Bacillus amyloliquefaciens D5, were investigated for their role in enhancing plant defense mechanisms against Cercospora canescens in mung bean (Vigna radiata L.). …”
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2827
Evaluation of Corrosion Potential Stability of Stainless Steels in Dilute Electrolyte Solution for Application to a Quasi-Reference Electrode Used in Electrochemical Sensing System
Published 2024-12-01“…The stability was increased by pre-immersion in an acidic solution but was reduced by a passivation treatment. The formation of iron oxides on the SS surface stabilized the potential, whereas surface enrichment with Cr led to instability. …”
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2828
La gestion de l’eau à Bibracte (Saône-et-Loire), avant et après la Conquête romaine
Published 2020-12-01“…First of all, during the Iron Age Bibracte was one of the main oppidum in Gaul. …”
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2829
Concentrations and associated health risks of indoor/outdoor PM2.5- bound metallic elements at a subway station in Tianjin city during winter
Published 2024-11-01“…The contents of antimony, manganese, alum, copper, cobalt, aluminum, chromium, lead, nickel, iron, sodium, magnesium, calcium, and zinc in PM2.5 samples collected on the subway platform were all significantly higher than those in PM2.5 samples collected outside the station (all P < 0.05). …”
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2830
Interactive effect of dietary metabolizable energy levels with amino acid density in male broiler chickens: Carcass yield, nutrient intake, digestibility and excretion
Published 2025-01-01“…Increasing AA density linearly increased nitrogen excretion, but reduced calcium and iron excretion (P < 0.05). Over the entire production period lower ME and higher AA density increased digestible lysine intake (mg/bird/day; P < 0.01). …”
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2831
Effect of diet containing alfalfa (Medicago sativa) powder and leaf extract on hemolymph factors of western whiteleg shrimp (Litopenaeus vannamei) under low salinity stress
Published 2024-06-01“…Discussion: Alfalfa leaves, rich in minerals like copper and iron and active compounds like flavonoids, contribute to increased hemocyte levels. …”
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2832
Low Frequency of MKRN3 and DLK1 Variants in Chinese Children with Central Precocious Puberty
Published 2019-01-01“…Per Glu380Lys, Glu with negative charges has been changed into Lys with positive charges, which may affect the hydrogen bond formation between amino acids and the stability of the local structure, thus affecting the binding of zinc iron to MKRN3 protein. Besides, we did not identify any variants of DLK1 gene in our patients. …”
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2833
The influence of environmental factors on the detection and quantification of SARS-CoV-2 variants in dormitory wastewater at a primarily undergraduate institution
Published 2025-02-01“…We observed significantly higher gene copy numbers of the Omicron variant than the Delta variant within ductile iron pipes but no difference in nucleocapsid abundance (N1 or N2) across the three different sewage pipe types in our data set. …”
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2834
Exosomes secreted by ATF3/Nrf2-mediated ferroptotic renal tubular epithelial cells promote M1/M2 ratio imbalance inducing renal interstitial fibrosis following ischemia and reperfu...
Published 2025-02-01“…In vitro, RTECs were divided into control (CON) group, hypoxia/reoxygenation (HR) group, HR +Fer-1 group, HR + siRNA-ATF3 (siATF3) group.ResultCompared with the sham group, the IR group showed more severe kidney injury in HE staining, more collagen fibers in Masson staining, and higher α-SMA expression levels in immunohistochemistry. Total iron and MDA content increased while GSH content decreased. …”
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2835
AnaDetect: An extensive dataset for advancing anemia detection, diagnostic methods, and predictive analytics in healthcareMendeley Data
Published 2025-02-01“…Common causes include blood loss, chronic diseases, and iron and vitamin deficiencies. This dataset captures various hematological parameters of patients suffering from anemia, including sex, age, Hemoglobin level (Hb), oxygen transportation (RBC), packed cell volume (PCV), mean corpuscular volume (MCV), Mean Corpuscular Hemoglobin (MCH), Mean corpuscular hemoglobin concentration (MCHC). …”
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2836
Hypoxia specifically induces CADM3 expression in pulmonary endothelial cells and promotes monocyte adhesion
Published 2025-01-01“…Cell adhesion experiments, siRNA interference, immunohistochemical assay, Western blotting, and flow cytometry were used to study the role of CADM3 in hypoxia specific high adhesion of HUVEC monocytes. Iron chelator deferoxamine (DFX) and shRNA interference were employed to enhance the expression of HIF-1α, and the effect of HIF-1 transcriptional activity on CADM3 expression was analyzed. …”
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2837
<i>Salmonella enterica</i> serovar Schwarzengrund: Distribution, Virulence, and Antimicrobial Resistance
Published 2025-01-01“…Notably, the aerobactin iron acquisition genes, associated with <i>Salmonella</i>’s virulence and colonization, were highly prevalent among chicken isolates (N = 1019, 89.0%) but less frequent in isolates from other sources (N = 65, 7.2%). …”
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2838
Effect of Moderate Red Meat Intake Compared With Plant-Based Meat Alternative on Psychological Well-Being: A 10-Wk Cluster Randomized Intervention in Healthy Young Adults
Published 2025-01-01“…Blood biomarkers included neurotransmitter-related compounds, iron status and vitamins B12 and D. Physical activity and sleep were estimated by a fitness wristband. …”
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2839
Nutritional intake of micronutrient and macronutrient and type 2 diabetes: machine learning schemes
Published 2025-02-01“…Result Nutritional intake in the T2D group showed that potassium, calcium, magnesium, zinc, iodine, carotene, vitamin D, tryptophan, and vitamin B12 had an inverse correlation with the incidence of diabetes (p < 0.05). While phosphate, iron, and chloride had a positive relationship with the risk of T2D (p < 0.05). …”
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2840
Bioinformatics analysis of ferroptosis-related hub genes and immunoinfiltration in myocardial ischemia/reperfusion following heart transplantation
Published 2025-01-01“…Unlike other modes of cell death, ferroptosis depends on the accumulation of iron within the cell and the oxidative degradation of polyunsaturated fatty acids. …”
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