Therapeutic Efficacy of Intranasal <i>N</i>-Acetyl-L-Cysteine with Cell-Penetrating Peptide-Modified Polymer Micelles on Neuropathic Pain in Partial Sciatic Nerve Ligation Mice by Hiroshi Nango, Ai Takahashi, Naoto Suzuki, Takumi Kurano, Saia Sakamoto, Taiki Nagatomo, Toyofumi Suzuki, Takanori Kanazawa, Yasuhiro Kosuge, Hiroko Miyagishi

“…Western blotting and immunohistochemistry were conducted to evaluate ionized calcium-binding adapter molecule 1 (Iba-1) expression and microglial activation in the spinal cord. …”
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3D-augmentation of 2D ultrasound for appendicitis diagnosis: A cross-sectional pilot study by Rebecca G. Theophanous, Elias Jaffa, Matthew R. Morgan, Carl D. Herickhoff, Erica Peethumnongsin, Joao Ricardo Nickenig Vissoci, Joshua S. Broder

“…Computed tomography (CT) is expensive with ionizing radiation. Three-dimensional ultrasound (3DUS) can capture multiplanar images using volume acquisition without radiation exposure. …”
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Low-Dose Irradiation Differentially Impacts Macrophage Phenotype in Dependence of Fibroblast-Like Synoviocytes and Radiation Dose by Lisa Deloch, Jana Fuchs, Michael Rückert, Rainer Fietkau, Benjamin Frey, Udo S. Gaipl

“…We now examined for the first time how LD-RT influences FLS and bone marrow-derived macrophages in co-culture systems of an experimental model of RA to reveal further mechanisms of immune modulatory effects of low and intermediate dose of ionizing radiation. For this, the bone marrow of hTNF-α tg mice was differentiated either with cytokines to obtain key macrophage phenotypes (M0, M1, and M2) or with supernatants (SN) of untreated or irradiated FLS. …”
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Radiation decreases bronchial epithelial progenitor function as assessed by organoid formation by Merian E. Kuipers, Dennis K. Ninaber, Krista C.J. van Doorn-Wink, Annelies M. Slats, Pieter S. Hiemstra

“…Since these effects are incompletely understood, the aim of the present study was to evaluate the effect of ionizing radiation (IR) on cultured well-differentiated primary bronchial epithelial cells (PBEC) with a focus on cytotoxicity, barrier formation, inflammation and epithelial progenitor function. …”
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Human Umbilical Cord Mesenchymal Stem Cells Attenuate Ocular Hypertension-Induced Retinal Neuroinflammation via Toll-Like Receptor 4 Pathway by Shangli Ji, Jie Xiao, Jian Liu, Shibo Tang

“…The expression levels of glial fibrillary acidic protein (GFAP), ionized calcium binding adapter molecule 1 (iba-1), and toll-like receptor 4 (TLR4) were assessed via immunohistochemistry, real-time quantitative PCR, and Western blot. …”
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The effect of ethanol extract of Aloysia triphylla on anesthesia and improve the physiological parameters of rainbow trout (Oncorhynchus mykiss) after transfer by Ali Hajibeglou, Masoumeh Machanlou, Mohammad Mazandarani, Mohammad Sudagar

“…After transport, lower blood serum glucose and cortisol and higher total protein, albumin, non-ionized ammonia, and dissolved oxygen levels in water were observed in fish exposed to 12.5 and 25 μL/L of the extract (p<0.05). …”
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A pelvis MR transformer-based deep learning model for predicting lung metastases risk in patients with rectal cancer by Yin Li, Yin Li, Yin Li, Shuang Li, Shuang Li, Ruolin Xiao, Ruolin Xiao, Xi Li, Yongju Yi, Yongju Yi, Liangyou Zhang, Liangyou Zhang, You Zhou, You Zhou, Yun Wan, Chenhua Wei, Liming Zhong, Liming Zhong, Wei Yang, Wei Yang, Lin Yao, Lin Yao, Lin Yao

“…Utilizing MR images to classify RCLM could potentially reduce ionizing radiation exposure and the costs associated with chest CT in patients without metastases. …”
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A Study of the Interaction Between Implanted Pacemakers and the Power-Frequency Field Produced by Traction Transformer in High-Speed EMU by Rui Tian, Yu-Long Zhang, Mai Lu, Jian-Fang Deng

“…All the B<inline-formula> <tex-math notation="LaTeX">$_{in~max}$ </tex-math></inline-formula>, E<inline-formula> <tex-math notation="LaTeX">$_{in~max}$ </tex-math></inline-formula> well within the basic limits established for public electromagnetic exposure set by the International Commission on Non-Ionizing Radiation. The Ein on the pacemakers of both passengers mainly appeared at the metal parts, and the B<inline-formula> <tex-math notation="LaTeX">$_{in~max}$ </tex-math></inline-formula> of passengers&#x2019; pacemakers is <inline-formula> <tex-math notation="LaTeX">$20.754~\mu $ </tex-math></inline-formula> T, which achieves the minimum requirements for pacemakers to anti-electromagnetic interference as specified by the International Organization for Standardization. …”
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Ultrasound-Guided Percutaneous Balloon Aortic Valvuloplasty for Aortic Stenosis by Yedan Li, Kunjing Pang, Yao Liu, Muzi Li, Hao Wang

“…Percutaneous balloon aortic valvuloplasty (PBAV), which is used to treat symptomatic aortic stenosis, requires ionizing radiation and contrast agent for imaging guidance. …”
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Conduction system pacing using electro-anatomical mapping-guided system vs. fluoroscopy: a systematic review, meta-analysis and economic evaluation by Beatriz León-Salas, Beatriz León-Salas, Beatriz León-Salas, Beatriz León-Salas, Diego Infante-Ventura, Diego Infante-Ventura, Diego Infante-Ventura, Aránzazu Hernández-Yumar, Aránzazu Hernández-Yumar, Aránzazu Hernández-Yumar, Renata Linertová, Renata Linertová, Renata Linertová, Renata Linertová, Estefanía Herrera-Ramos, Estefanía Herrera-Ramos, Estefanía Herrera-Ramos, Estefanía Herrera-Ramos, Alezandra Torres-Castaño, Alezandra Torres-Castaño, Alezandra Torres-Castaño, Alezandra Torres-Castaño, Himar González-Pacheco, Himar González-Pacheco, Himar González-Pacheco, Himar González-Pacheco, Analía Abt-Sacks, Analía Abt-Sacks, Analía Abt-Sacks, Analía Abt-Sacks, Javier García-García, Raúl Quirós-López, Raúl Quirós-López, María M. Trujillo-Martín, María M. Trujillo-Martín, María M. Trujillo-Martín, María M. Trujillo-Martín

“…The use of EAM represents an increase of EUR 1397.81 per patient and a net budget impact of EUR 1.63 million.DiscussionEAM is a valuable alternative for patients who should not be exposed to ionizing radiation with similar effectiveness and safety than fluoroscopy. …”
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Sevoflurane Exacerbates Cognitive Impairment Induced by Aβ1–40 in Rats through Initiating Neurotoxicity, Neuroinflammation, and Neuronal Apoptosis in Rat Hippocampus by Yue Tian, Ke-yan Chen, Li-dan Liu, Yun-xia Dong, Ping Zhao, Shan-bin Guo

“…Sevoflurane inhalation but not O2 significantly increased glial fibrillary acidic protein (GFAP) and ionized calcium-binding adaptor molecule (IBA)1 expression in Aβ-treated hippocampus of rats. …”
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Balancing act: optimizing blue light for melanogenesis while minimizing cellular damage in primary human skin cells by Augustin C. Barolet, Augustin C. Barolet, Augustin C. Barolet, Augustin C. Barolet, Brice Magne, Brice Magne, Brice Magne, Karel Ferland, Karel Ferland, Karel Ferland, Natallia E. Uzunbajakava, Daniel Barolet, Daniel Barolet, Lucie Germain, Lucie Germain, Lucie Germain

“…This study aimed to determine the cell damage threshold of non-ionizing blue light on keratinocytes while preserving their ability to stimulate melanogenesis.MethodsHuman keratinocytes (N = 3) and melanocytes (N = 3) were isolated from skin samples of varying Fitzpatrick skin phototypes and irradiated with blue light (λpeak = 457 nm) and UVA light (λpeak = 385 nm). …”
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Serum Level Alteration of IL-6, IL-1β, and IFN-γ in Groups of Healthy Adults with Oxidative DNA Damage in Najaf Governorate by Dhuha S. Saleh, Hayder S. Hussain, Hasan N. Al-Haidari, Samia K. Abbas, Ayaid K. Zgair, Seenaa M. Ali

“…The change in the proinflammatory cytokines (IL-6, IFN-γ, and IL-1β) levels indicates a persistent inflammatory response in the participants and may reflect immune system impairment as a consequence of exposure to long-term low-dose ionizing radiation.…”
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Combinatorial functionomics identifies HDAC6-dependent molecular vulnerability of radioresistant head and neck cancer by Sharon Pei Yi Chan, Celestia Pei Xuan Yeo, Boon Hao Hong, Evelyn Mui Cheng Tan, Chaw Yee Beh, Eugenia Li Ling Yeo, Dennis Jun Jie Poon, Pek Lim Chu, Khee Chee Soo, Melvin Lee Kiang Chua, Edward Kai-Hua Chow

“…Results We report the therapeutic potential of combining panobinostat (pan-HDAC inhibitor) with AZD7762 (CHK1/2 inhibitor; AstraZeneca) or ionizing radiation (IR) to re-sensitize RR-HNC cells and showed increased DNA damage underlying enhanced synergy. …”
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Robotic Assistance is Associated With No Intraoperative Fluoroscopy or Radiation Exposure During Direct Anterior Total Hip Arthroplasty by Sean Sequeira, MD, Alan Brett, PhD, Joseph Nessler, MD, Benjamin Frye, MD, Michael A. Mont, MD

“…As more surgeons, patients, and surgical staff are exposed to an increasing number of orthopaedic procedures that require ionizing radiation to generate images, such as fluoroscopy and CT, it is important to consider the radiation dosage for all individuals and understand the positives and negatives of each treatment. …”
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Preliminary study on the correlation between thyroid magnetic resonance parameters and radiation dose after radiotherapy for nasopharyngeal carcinoma by Kuan Lu, Chenxia Zhou, Jiaming Ren, Jialu Ni, Weisen Yang, Yeqing Wang, Dan Jin, Jianjun Qian, Yaqun Zhu, Dai Shi, Wentao Hu, Liang Xu

“…Magnetic resonance imaging (MRI) has gained prominence in thyroid imaging, leveraging its non-ionizing radiation, high spatial resolution, multiparameter and multidirectional imaging. …”
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Radiation hazards from natural radionuclides contained in rice from former tin mining land by J. Mellawati, N. Madyaningarum, E.A. Fajrianshah, E.B. jumpeno, T.R.D. Larasati, N. Mulyana, E. Nurtjahya, K. Khotimah

“…Radionuclides found in rice can potentially lead to exposure to ionizing radiation, thereby influencing the likelihood of developing. …”
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4-1BB agonist targeted to fibroblast activation protein α synergizes with radiotherapy to treat murine breast tumor models by Ignacio Melero, Alvaro Teijeira, Christian Klein, Maria E Rodriguez-Ruiz, Christina Claus, Pablo Umana, Tamara Tanos, Carlos E De Andrea, Carlos Luri-Rey, Paloma Sanchez-Mateos, Leticia Fernández-Rubio, María Collantes, Irantzu Serrano-Mendioroz, Celia Barrio-Alonso, Antonio Rullan, Jon Ander Simon, Eneko Garate-Soraluze, Claudia del Pilar Herrero

“…Background Ionizing radiation (IR) is a double-edged sword for immunotherapy as it may have both immunosuppressive and immunostimulatory effects. …”
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Borrelia burgdorferi radiosensitivity and Mn antioxidant content: antigenic preservation and pathobiology by Andrés F. Londoño, Ajay Sharma, Jared Sealy, Vipin S. Rana, Shelby D. Foor, Vera Y. Matrosova, Elena K. Gaidamakova, Robert P. Volpe, Michael J. Daly, Brian M. Hoffman, Utpal Pal, J. Stephen Dumler

“…These observations also provide an opportunity for innovative vaccine development strategies employing ionizing radiation to disrupt the B. burgdorferi genome, while maintaining antigenic potency. …”
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Cooling and Sterile Inflammation in an Oxygen-Glucose-Deprivation/Reperfusion Injury Model in BV-2 Microglia by Jana Lücht, Nele Rolfs, Sylvia J. Wowro, Felix Berger, Katharina R. L. Schmitt, Giang Tong

“…Furthermore, inducible nitric oxide synthase (iNOS), ionized calcium-binding adaptor molecule 1 (Iba1), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), interleukin-1β (IL-1β), interleukin-1α (IL-1α), monocyte chemotactic protein 1 (MCP-1), transforming growth factor β (TGFβ), CIRBP, and RBM3 gene expressions were assessed via reverse transcription polymerase chain reaction, and TNF-α, IL-6, and IL-1β releases into the cultured supernatants were assessed via enzyme-linked immunosorbent assays (ELISA). …”
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