Portulaca oleracea L. (purslane) extract ameliorates intestinal inflammation in diet-induced obese mice by inhibiting the TLR4/NF-κB signaling pathway by Lingchao Miao, Meng Sam Cheong, Haolin Zhang, Haroon Khan, Haroon Khan, Hongxun Tao, Yuxiao Wang, Wai San Cheang

“…Pro-inflammatory cytokines were determined using ELISA kits, whereas the components of purslane extract were detected by ultra performance liquid chromatography/electrospray ionization quadrupole time-of-flight mass spectrometry. …”
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Simultaneous Determination of 13 Constituents of Radix Polygoni Multiflori in Rat Plasma and Its Application in a Pharmacokinetic Study by Wenhao Cheng, Yinghui Li, Wei Yang, Siyang Wu, Mengmeng Wei, Yang Gao, Chen Kang, Shuofeng Zhang, Yingfei Li

“…The constituents were detected in negative ionization mode using multiple reaction monitoring. …”
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Effects of helium irradiation damage on deuterium plasma-driven permeation through tungsten coated RAFM steel by Yue Xu, Xiao-Ping Tian, Hong-Yan Tan, Hai-Ying Fu, Jun-Jie Ni, Lai-Ma Luo, Yu-Cheng Wu

“…The results indicated that the presence of He reduced the ionization rate of the D plasma and decreased D-PDP flux. …”
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The Northern and Southern Hemispheric Asymmetries of Mesospheric Ozone at High Latitudes During the January 2012 Solar Proton Events by Shiping Xiong, Jingyuan Li, Guanchun Wei, Jianyong Lu, Yufeng Tian, Xiaoping Zhang, Shuai Fu, Meng Sun, Zheng Li, Hua Zhang, Jingqi Cui, Shuwen Jiang, Chaolei Yang

“…The mesospheric ozone at high latitudes decreased evidently with the increasing proton flux and ionization rates during SPEs. The results of SABER and WACCM‐X both showed that maximum mesospheric ozone depletion reached 100% in the North Hemispheric (NH) high latitudes during SPEs while only 40% in the South Hemispheric (SH) high latitudes. …”
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Determination of Organophosphorus Esters in Fall Protection Equipment by Accelerated Solvent Extraction and Solid-Phase Extraction Coupled with LC-MS/MS Detection by Haihong Li, Mingli Ye, Fangfang Wu, Xuyang Zhao, Lifeng Wang, Yili Wei, Shengyi Xie, Hairong Cui

“…A HILIC column was used to separate the OPEs using an acetonitrile/water mixture as the mobile phase with the detection by the electrospray ionization mass spectrometry, which was operated under the positive mode. …”
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Simultaneous Determination of Multiple Active Components from Bushen Pills and Application in a Pharmacokinetic Study in Rats by Houli Li, Benjie Wang, Guiyan Yuan, Xiaoyan Liu, Jing Huang, Lilong Xiong, Di Zhang, Weiyi Feng, Ruichen Guo

“…Three active constituents of BSPs, including paeoniflorin (PF), berberine hydrochloride (BBR), and schizandrin (SCH), were simultaneously determined by the established LC-MS method with electrospray ionization (ESI) in positive selected ion monitoring (SIM) mode at m/z 503.1, 336.0, and 455.2. …”
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Photosynthetic Pigments with Potential for a Photosynthetic Antenna: A DFT Analysis by Jesús Francisco Monzón-Bensojo, Manuel A. Flores-Hidalgo, Diana Barraza-Jiménez

“…The evaluated electronic properties at the gas phase included (a) energies such as HOMO-LUMO band gap (H-L, ranging from 2.168 to 2.504 eV), adiabatic ionization potential (I, ranging from 5.964 to 7.207 eV), and adiabatic electronic affinity (A, ranging from 2.176 to 2.741 eV); (b) global chemical reactivity indexes such as electronegativity (χ, ranging from 4.121 to 4.974 eV), hardness (η, ranging from 1.812 to 2.233 eV), electrophilicity index (ω, ranging from 4.365 to 5.541 eV), and electroaccepting-electrodonating powers (ω+, ranging from 1.671 to 2.115 eV, and ω−, ranging from 4.375 to 5.273 eV); (c) electron-hole reorganization energies (λ, ranging from 0.225 to 0.519 eV and ranging from 0.168 to 0.425 eV, respectively) and electron-hole extraction potentials (EEP, ranging from 2.570 to 2.966 eV, and HEP, ranging from 5.538 to 7.012 eV, respectively); and (d) local chemical reactivity indexes like condensed Fukui functions (fk), condensed dual descriptor (f2r), and condensed local softness (sk). …”
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Phytochemicals of Vitis vinifera L. var. King Ruby protect mice from benzo(a)pyrene-induced lung injury by Gehad S. Ahmedy, Hend M. Selim, Mona El-Aasr, Souzan M. Ibrahim, Suzy A. El-Sherbeni

“…King Ruby leaves methanol extract (VLME) was tentatively recognized by liquid chromatography electrospray ionization tandem mass spectrometric (LC-ESI-MS/MS). …”
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Epsilon Canis Majoris: The Brightest Extreme-ultraviolet Source with Surprisingly Low Interstellar Absorption by J. Michael Shull, Rachel M. Curran, Michael W. Topping

“…The photoionization rate Γ _H ≈ (1–2) × 10 ^−14 s ^−1 at the cloud surface produces an ionization fraction (30%–40%) for total hydrogen density n _H = 0.2 cm ^−3 . …”
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Elevation of ganglioside degradation pathway drives GM2 and GM3 within amyloid plaques in a transgenic mouse model of Alzheimer's disease by Wenxuan Wang, Sarah J. Myers, Nikita Ollen-Bittle, Shawn N. Whitehead

“…To address this gap, matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) was employed to investigate the age-dependent expression profiles of the A-series ganglioside species GD1a, GM1, GM2, and GM3 in the APP/PS1 transgenic mouse model of AD in which age-dependent amyloid-beta (Aβ) plaques develop. …”
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Biocontrol Potential of Rhizospheric Bacillus Strains Against <i>Sclerotinia minor</i> Jagger Causing Lettuce Drop by Lihui Xu, Qinghua Shang, Mogens Nicolaisen, Rong Zeng, Shigang Gao, Ping Gao, Zhiwei Song, Fuming Dai, Jingze Zhang

“…Lipopeptide compounds produced by each strain were identified using matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI–TOF MS) analysis. …”
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Distribution and Antifungal Susceptibility Profile of Oropharyngeal Candida Species Isolated from People Living with HIV in the Era of Universal Test and Treat Policy in Uganda. by Musinguzi, Benson, Turyamuhika, Laban, Mwesigwa, Alex, Nalumaga, Pauline Petra, Kabajulizi, Immaculate, Njovu, Israel Kiiza, Mwebesa, Edson, Luggya, Tonny, Ocheng, Francis, Kateete, David Patrick, Itabangi, Herbert, Mboowa, Gerald, Obondo, James Sande, Achan, Beatrice

“…Oropharyngeal swabs were collected and cultured on Sabouraud Dextrose agar to isolate Candida species identified using the matrix-assisted laser desorption ionization-time of flight mass spectrometry. Additionally, the antifungal susceptibility profile of Candida isolates to six antifungal drugs was determined using the VITEK® (Marcy-l’Étoile, France) compact system. …”
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SiC free-standing membrane for X-ray intensity monitoring in synchrotron radiation beamlines by Gabriele Trovato, Marzio De Napoli, Christian Gollwitzer, Simone Finizio, Michael Krumrey, Francesco La Via, Luca Lanzanò, Giuliana Milluzzo, Samuele Moscato, Matthias Müller, Francesco Romano, Dario Ferreira Sanchez, Massimo Camarda

“…Traditional transmission-mode monitors included metal mesh foils and ionization chambers, which suffered from low signal stability and size constraints. …”
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Mass Fragmentation Characteristics of t-Boc Substituted Drug Precursors by Cui-mei LIU, Xue-yan LIU, Zhen-dong HUA, Hao TANG, Yu DU, Wei JIA

“…After analyzing the characteristic fragment ions under electron impact (EI) mode and electrospray ionization collision-induced dissociation (ESI-CID) mode, the possible fragmentation pathways of t-Boc substituted drug precursors were deduced. …”
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Online target normal sheath acceleration proton beam stabilization at 1 Hz in ultra-intense laser–matter interaction by Jose Luis Henares, Michael Ehret, Jon Apiñaniz, Carlos Salgado-López, José Antonio Pérez-Hernández, María Luisa Berlanga, Ana María Cives Fernández, Evgeny Filippov, Enrique García-García, Rubén Hernández Martín, Diego De Luis, Pilar Puyuelo-Valdes, Isabel Rodríguez-Pérez, María Dolores Rodríguez Frías, Iuliana-Mariana Vladisavlevici, Giancarlo Gatti

“…In addition, non-invasive detectors, such as a target charging monitor and ionization chamber detectors, were tested as metrology for the stability of the source. …”
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Ion suppression correction and normalization for non-targeted metabolomics by Iqbal Mahmud, Bo Wei, Lucas Veillon, Lin Tan, Sara Martinez, Bao Tran, Alexander Raskind, Felice de Jong, Yiwei Liu, Jibin Ding, Yun Xiong, Wai-kin Chan, Rehan Akbani, John N. Weinstein, Chris Beecher, Philip L. Lorenzi

“…We evaluate the method across ion chromatography (IC), hydrophilic interaction liquid chromatography (HILIC), and reversed-phase liquid chromatography (RPLC)-MS systems in both positive and negative ionization modes, with clean and unclean ion sources, and across different biological matrices. …”
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Phytochemical and Biological Investigations of Crude Extracts of <i>Astragalus pisidicus</i> by Esra Aydemir, Elif Odabaş Köse, Serap Özkaya Gül, Alaaddin Korkut, A. Cansu Kilit, Mehmet Engin Celep, Mustafa Yavuz, R. Süleyman Göktürk, Cengiz Sarikurkcu

“…<b>Methods</b>: The water and methanolic fractions of four parts (stems, flowers, leaves, root) as well as the whole plant were quantified and identified by Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry (LC–ESI–MS/MS) analysis. …”
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Anti-Inflammatory Activity of Diterpenoids from Celastrus orbiculatus in Lipopolysaccharide-Stimulated RAW264.7 Cells by Hyun-Jae Jang, Kang-Hoon Kim, Eun-Jae Park, Jeong A. Kang, Bong-Sik Yun, Seung-Jae Lee, Chan Sun Park, Soyoung Lee, Seung Woong Lee, Mun-Chual Rho

“…In this study, compounds 1–17, including undescribed podocarpane-type trinorditerpenoid (3), were purified from C. orbiculatus and their chemical structure were determined by high-resolution electrospray ionization mass (HRESIMS) and nuclear magnetic resonance (NMR) spectroscopic data. …”
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Simultaneous Determination of Multiple Acid-Suppressing Drugs by UPLC-MS/MS Method and Application for Pharmacokinetics Study by Li X, Liu S, Yu M, Xi W, Wu X, Liu D, Liu A, Wang H

“…Detection was performed on a triple quadrupole tandem mass spectrometer with positive electrospray ionization. Chromatographic separation was achieved on the ACQUITY UPLC BEH C18 column (2.1 × 50 mm, 1.7 μm) using gradient elution. …”
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UPLC-ESI-MS/MS Profile and Antioxidant, Cytotoxic, Antidiabetic, and Antiobesity Activities of the Aqueous Extracts of Three Different Hibiscus Species by Hanan M. Al-Yousef, Wafaa H. B. Hassan, Sahar Abdelaziz, Musarat Amina, Rasha Adel, May A. El-Sayed

“…This inspired the authors to investigate the phytochemicals of these extracts for the first time using UPLC-ESI-MS/MS in negative and positive ionization modes. The analysis afforded the tentative identification of 103 compounds including phenolic compounds, flavonoids, and anthocyanins. …”
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