Unveiling cellular changes in leukaemia cell lines after cannabidiol treatment through lipidomics by David Chamoso-Sanchez, Martina Panini, Clarissa Caroli, Matilde Marani, Lorenzo Corsi, Francisco J Rupérez, Antonia Garcia, Federica Pellati

“…After the extraction of the lipid content from cell lysates, the samples were analysed by UHPLC-QTOF-MS/MS both in the positive and the negative ionization modes. The comprehensive characterization of cellular lipids unveiled several classes significantly affected by CBD treatment. …”
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Pharmacokinetics of Eight Flavonoids in Rats Assayed by UPLC-MS/MS after Oral Administration of Drynariae rhizoma Extract by Zhan-Ling Xu, Ming-Yue Xu, Hai-Tao Wang, Qing-Xuan Xu, Ming-Yang Liu, Chun-Peng Jia, Fang Geng, Ning Zhang

“…The detection was performed using a triple quadrupole tandem mass spectrometer equipped with an electrospray ionization interface (ESI) by multiple reaction monitoring (MRM) in the positive ion mode. …”
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Cell-free supernatants from plant growth-promoting rhizobacteria Bacillus albus strains control Aspergillus flavus disease in peanut and maize seedlings by Lai Loi Trinh, Kim Ngoc Le, Hoang Anh Le Lam, Hoai Huong Nguyen

“…These were characterized using rapid chemical assays and ultra-high-performance liquid chromatography-electrospray ionization-quadrupole time-of-flight/mass spectrometry (UHPLC-ESI-QTOF/MS), combined with bioinformatic tools such as Global Natural Product Social Molecular Networking (GNPS) and Natural Products Atlas (NPAtlas). …”
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Altitude Extension of the NCAR‐TIEGCM (TIEGCM‐X) and Evaluation by Yihui Cai, Xinan Yue, Wenbin Wang, Shun‐Rong Zhang, Huixin Liu, Dong Lin, Haonan Wu, Jia Yue, Sean L. Bruinsma, Feng Ding, Zhipeng Ren, Libo Liu

“…The latitude‐altitude distribution of the equatorial ionization anomaly derived from TIEGCM‐X is more reasonable. …”
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Assessment of the Chemical Diversity and Functional Properties of Secondary Metabolites from the Marine Fungus <i>Asteromyces cruciatus</i> by María Paz González-Troncoso, Catalina Landeta-Salgado, Javiera Munizaga, Ruth Hornedo-Ortega, María del Carmen García-Parrilla, María Elena Lienqueo

“…Crude extracts of fungal biomass were analyzed for total phenolic content (TPC), antioxidant capacity (TAC), toxicity, and phenolic compound identification using ultra-high-performance liquid chromatography coupled with high-resolution electrospray ionization mass spectrometry (UHPLC-MS/MS). The analysis revealed the presence of anthraquinone compounds, including emodin (0.36 ± 0.08 mg/g DW biomass) and citrereosein in glucose medium and citrereosein and endocrocin in <i>M. pyrifera</i> medium. …”
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Evaluation of Antibiotic Resistance and Biofilm Production among Clinical Strain Isolated from Medical Devices by Veronica Folliero, Gianluigi Franci, Federica Dell’Annunziata, Rosa Giugliano, Francesco Foglia, Rossella Sperlongano, Anna De Filippis, Emiliana Finamore, Massimiliano Galdiero

“…Identification of isolates and antibiotic susceptibility testing were performed using Matrix Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) and Phoenix Becton Dickinson, respectively. …”
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Biotechnological Approach for Development and Characterization of Protein Feed for <i>Melipona quadrifasciata</i> by Patrícia Miranda-Pinto, Jullio Kennedy Castro Soares, Irys Hany Lima Gonzalez, Yuri Ribeiro Diogo, Lívia Soman de Medeiros, Luciana Chagas Caperuto, Patrícia Locosque Ramos, Tiago Maurício Francoy, Michelle Manfrini Morais

“…The metabolomic analysis identified 85 compounds in positive and 102 in negative ionization modes. Shared metabolites, such as isoquercetin and palatinose, highlighted similarities between the feed and natural fermented pollen. …”
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Wettability alteration and IFT reduction during carbonated water injection; a critical investigation into the role of pH by Zoha Dalal Isfehani, Jalal Fahimpour, Mohammad Sharifi, Hossein Khalili, Mohammad Saeid Tayebi

“…This reduction is attributed to the ionization of the oil’s basic components, which act as natural surfactants, while the acidic components remain neutral. …”
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Assessment-Based Optimization of Distillation Parameters by Ludmila N. Krikunova, Elena V. Dubinina, Dmitry A. Sviridov, Svetlana M. Tomgorova

“…The composition and mass concentration of the main volatile components were determined by gas chromatography using a Thermo Trace GC Ultra device (Thermo, USA) with a flame ionization detector. The sensory evaluation was performed by a panel of qualified experts. …”
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Simultaneous Quantification of Aspirin, Its Metabolite Salicylic Acid, and Salvianolic Acid B in Human Plasma Using UPLC-MS/MS by Weiyi Cao, Hezhi Yao, Zhenzhen Qian, Yi Wu, Shuge Wang, Rui Li, Rui Gao

“…Salvianolic acid B, acetylsalicylic acid, and salicylic acid were quantified in multiple-reaction monitoring mode with negative ion electrospray ionization. The method was fully validated according to the current regulatory guidance for bioanalysis. …”
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Antioxidant and Chelating Activity of Nontoxic Jatropha curcas L. Protein Hydrolysates Produced by In Vitro Digestion Using Pepsin and Pancreatin by Santiago Gallegos Tintoré, Cristina Torres Fuentes, Javier Solorza Feria, Manuel Alaiz, Julio Girón Calle, Alma Leticia Martínez Ayala, Luis Chel Guerrero, Javier Vioque

“…Peptidic fractions with higher radical scavenging activity were analysed by matrix-assisted laser desorption/ionization mass spectrometry. The antioxidant activity was determined by measuring inhibition of the oxidative degradation of β-carotene and by measuring the reactive oxygen species (ROS) in Caco-2 cell cultures. …”
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Identification of Potential Serum Metabolic Biomarkers of Diabetic Kidney Disease: A Widely Targeted Metabolomics Study by Hang Zhang, Jing-jing Zuo, Si-si Dong, Yuan Lan, Chen-wei Wu, Guang-yun Mao, Chao Zheng

“…The ultraperformance liquid chromatography-electrospray ionization-tandem mass spectrometry system was applied for the assessment of the serum metabolic profiles. …”
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Dose-dependent effects of gamma radiation on the early zebrafish development and gene expression. by Selma Hurem, Leonardo Martín Martín, Dag Anders Brede, Eystein Skjerve, Rasoul Nourizadeh-Lillabadi, Ole Christian Lind, Terje Christensen, Vidar Berg, Hans-Christian Teien, Brit Salbu, Deborah Helen Oughton, Peter Aleström, Jan Ludvig Lyche

“…Ionizing radiation from natural sources or anthropogenic activity has the potential to cause oxidative stress or genetic damage in living organisms, through the ionization and excitation of molecules and the subsequent production of free radicals and reactive oxygen species (ROS). …”
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Changes in the rhizosphere metabolome profile of wastewater-irrigated lettuces (Lactuca sativa L.) highlighted using non-target HRMS and ROIMCR chemometrics method by Carlos Pérez-López, Lúcia H.M.L.M. Santos, Antoni Ginebreda, Lucas L. Alonso, Gianluigi Buttiglieri, Evangelos Statiris, Damia Barcelo, Sara Rodriguez-Mozaz, Roma Tauler

“…Non-target metabolomic profiling was performed using the Regions of Interest procedure (ROI), followed by Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS) for simultaneous analysis of MS1 and MS2 signals in positive and negative ionization modes. In total, 37 chemical compounds (endogenous and exogenous) were identified belonging to different classes and origins, such as several sesquiterpene lactones or flavonoids that play a key role in the secondary metabolism of plants. …”
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Pharmacokinetic Analysis of Diosgenin in Rat Plasma by a UPLC-MS/MS Approach by Pei Liu, Lin Xu, Jing-han Guo, Jin-hua Chang, Xi-gang Liu, He-fei Xue, Ru-xing Wang, Zhong-si Li, Guang-xin Miao, Cui-zhe Liu, Jian-yu Zhou

“…MS with positive electron spray ionization in multiple reaction monitoring modes was applied to determine diosgenin and IS with m/z 415.2⟶271.2 and m/z 295.2⟶277.1, respectively. …”
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Revisiting the Ionospheric Disturbances Over Low Latitude Region of China During Super Typhoon Hato by Ke Li, Donghe Zhang, Yi Zeng, Yaoyu Tian, Guofeng Dai, Zhizhao Liu, Guanglin Yang, Shuji Sun, Guozhu Li, Yongqiang Hao, Zuo Xiao

“…This enhancement covers the northern and southern equatorial ionization anomaly (EIA) region from 80°E to 180°E. …”
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Potential Clinical Application of Analysis of Bisphenols in Pericardial Fluid from Patients with Coronary Artery Disease with the Use of Liquid Chromatography Combined with Fluores... by Tomasz Tuzimski, Szymon Szubartowski, Janusz Stążka, Kamil Baczewski, Daria Janiszewska, Viorica Railean, Bogusław Buszewski, Małgorzata Szultka-Młyńska

“…Quantitative analysis of bisphenols in the samples was then performed by LC–MS/MS on a triple quadrupole (QqQ) mass spectrometer and electrospray ionization (ESI-/ESI+) was applied in the negative and positive ion modes, respectively. …”
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Development and Application of a LC-MS/MS Method for Simultaneous Quantification of Four First-Line Antituberculosis Drugs in Human Serum by Yunliang Zheng, Nana Xu, Xingjiang Hu, Qiao Zhang, Yanpeng Liu, Qingwei Zhao

“…MS detection was performed by a triple quadrupole tandem mass spectrometer in the multiple reaction monitoring mode with a positive electrospray ionization source. Isotope-labeled internal standard, especially rifampicin-D8, was applied to adjust for the loss during sample treatment. …”
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The transport of polyphenols from Camellia fascicularis in Caco-2 cells based on UPLC-ESI-MS/MS by Shengjiang Duan, Hao Zheng, Junrong Tang, Huan Kan, Changwei Cao, Zhijiao Shi, Yun Liu

“…Herein, digestion samples (DS) of C. fascicularis polyphenols (CFPs) were metabolically analyzed based on their bidirectional translocation in Caco-2 cells using ultraperformance liquid chromatography-electrospray ionization-tandem mass spectrometry. The results indicated that after DS transported via Caco-2 cell monolayer models nine polyphenol compounds in transit solution (TSB) from apical (AP) to basolateral (BL) side were upregulated, whereas seven in the transit solution (TSA) from BL to AP side were upregulated. …”
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Multimodality Imaging Probe for Positron Emission Tomography and Fluorescence Imaging Studies by Suresh K. Pandey, Jasmeet Kaur, Balu Easwaramoorthy, Ankur Shah, Robert Coleman, Jogeshwar Mukherjee

“…Molecular weight determined using matrix-associated laser desorption ionization (MALDI) for the BSA sample was 66,485 Da and for biotin-BSA was 67,116 Da, indicating two biotin moieties per BSA molecule; for biotin-BSA-DTPA was 81,584 Da, indicating an average of 30 DTPA moieties per BSA molecule; and for FAM conjugate was 82,383 Da, indicating an average of 1.7 fluorescent moieties per BSA molecule. …”
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