Identification and Analysis of Components in Yizhi Granule and Cynomolgus Monkey Plasma after Oral Administration by UPLC/ESI-Q-TOF MS and Their Protective Effects on PC12 Cells by Erwei Hao, Jianfeng Qin, Wei Wei, Jianhua Miao, Yan Xie, Xianglong Pan, Hangxuan Wu, Jinling Xie, Xiaosu Fan, Zhengcai Du, Xiaotao Hou, Jiagang Deng

“…Here, we describe the first fast and sensitive ultraperformance liquid chromatography/electrospray ionization quadrupole time-of-flight mass spectrometry (UPLC/ESI-Q-TOF MS) method for analyzing YZG in plasma. …”
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Efficacy of Moringa oleifera Seed Husk as Adsorptive Agent for Trihalomethanes from a Water Treatment Plant in Southwestern, Nigeria by Aderonke Adetutu Okoya, Olasunkanmi Olalekan Olaiya, Abimbola Bankole Akinyele, Nnenneh Oruada Ochor

“…The physicochemical properties of both the treated and raw surface water were determined using standard methods, and the concentration of THMs was determined from the water treatment plant at different stages of treatment using gas chromatography with flame ionization detector (GC-FID). Recovery experiments were carried out to validate the procedure. …”
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Analysis of Polycyclic Aromatic Hydrocarbon in Airborne Particulate Matter Samples by Gas Chromatography in Combination with Tandem Mass Spectrometry (GC-MS/MS) by Nam Vu-Duc, Lan Anh Phung Thi, Thuy Le-Minh, Lan-Anh Nguyen, Huong Nguyen-Thi, Loan-Ha Pham-Thi, Van-Anh Doan-Thi, Huong Le-Quang, Hung Nguyen-Xuan, Thao Thi Nguyen, Phuong Thanh Nguyen, Dinh Binh Chu

“…In this work, a capillary gas chromatography coupled with electron impact ionization tandem mass spectrometry (GC-EI-MS/MS) has been introduced for analysis of 16 PAHs in some particulate matter samples. …”
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Surface Modification of TFC-PA RO Membrane by Grafting Hydrophilic pH Switchable Poly(Acrylic Acid) Brushes by Muhammad Asad Abbas, Shehla Mushtaq, Waqas A. Cheema, Hazim Qiblawey, Shenmin Zhu, Yao Li, Runnan Zhang, Hong Wu, Zhongyi Jiang, Rehan Sadiq, Nasir M. Ahmad

“…At these pH values, ionization of the COOH group takes place below and above pKa to influence the effective pore dimension of the modified membranes. …”
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Niacin alters ruminal microbial composition and metabolites in sheep fed a high-concentrate diet by Zhiqiang Cheng, Jiancheng Liu, Yingying Yu, Wentao Liu, Xiaobin Li, Fengming Li, Changjiang Zang, Kailun Yang

“…The concentrations of NH3-N (p < 0.01), propionate (p < 0.01), and butyrate (p < 0.05) in the NA group were significantly higher than those in the CON group. (3) Compared to the CON group, the ruminal pyruvate content in the NA group was significantly increased at 0 h before feeding (p < 0.05), and lactic acid (p < 0.05) was significantly decreased at 1 and 3 h after feeding, lactate dehydrogenase activities was significantly decreased (p < 0.01) at 3 and 5 h after feeding. (4) The number of specific operational taxonomic units (OTUs) in the CON and NA groups were 26 and 37, respectively, for a total of 1,178 OTUs; principal coordinate analysis (R2 = 0.172, p-value = 0.007) and non-metric multidimensional scaling (stress = 0.1646) results showed that the two groups of samples were significantly separated. (5) The species distribution bar graph shows that at the phylum level, the relative abundances of Bacteroidetes, Firmicutes, and Proteobacteria were 43.70, 36.25, and 12.77%, respectively. (6) Orthogonal projection to latent structure-discriminant analysis results showed that the two groups of samples were clearly separated in the positive and negative ionization modes, with R2Y and Q2Y values of 0.705, 0.857, 0.695, and 0.28, respectively. …”
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Investigating the neuroprotective effects of Dracocephalum moldavica extract and its effect on metabolomic profile of rat model of sporadic Alzheimer's disease by Marjan Talebi, Seyed Abdulmajid Ayatollahi, Mohammad Ali As’Habi, Farzad Kobarfard, Mona Khoramjouy, Farzaneh Niki Boroujeni, Mehrdad Faizi, Alireza Ghassempour

“…Matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) was used to assess metabolite changes in various brain regions. …”
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Identification of glutamine as a potential therapeutic target in dry eye disease by Xiaoniao Chen, Chuyue Zhang, Fei Peng, Lingling Wu, Deyi Zhuo, Liqiang Wang, Min Zhang, Zhaohui Li, Lei Tian, Ying Jie, Yifei Huang, Xinji Yang, Xiaoqi Li, Fengyang Lei, Yu Cheng

“…In situ metabolomics through matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) revealed increased glutamine levels in cornea following MSC + Tβ4 combined therapy. …”
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Analysis of the efficacy of MALDI-TOF MS technology in identifying microorganisms in cancer patients and oncology hospital environment by Grażyna Czeszewska-Rosiak, Iwona Adamczyk, Agnieszka Ludwiczak, Piotr Fijałkowski, Paweł Fijałkowski, Magdalena Twarużek, Michał Złoch, Dorota Gabryś, Wioletta Miśta, Andrzej Tretyn, Paweł Piotr Pomastowski

“…The study was conducted to evaluate the effectiveness of the matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI TOF MS) technology in the microbial profiling of hospital environments and patient samples. …”
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Establishment and evaluation of a UPLC-MS/MS method for simultaneous determination of bongkrekic acid and dehydroacetic acid in rice noodles by Lingguo Zhao, Ronggui Lv, Ronggui Lv, Jiang Song, Xi Chen, Lei Lei, Weixian Zeng, Miaowen She, Miaowen She, Dabing Li, Xiaxia Yu, Zhanguo Liu, Xiao Wang, Yong Liu

“…The extraction solvent consisted of a mixture of methanol, ammonia, and water. Electrospray ionization negative ion mode (ESI-) was used for multiple reaction detection and external standard method was used for quantitative determination. …”
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Speciation Analysis of Arsenic Compounds by High-Performance Liquid Chromatography in Combination with Inductively Coupled Plasma Dynamic Reaction Cell Quadrupole Mass Spectrometry... by Hai Anh Vu, Manh Ha Nguyen, Hong-An Vu-Thi, Quan Do-Hong, Xuan Hoang Dang, Thi Ngoc Bich Nguyen, Hong Quan Trinh, Thuy Ly Bich, Tien-Thanh Nguyen, Dung Le-Van, Minh Binh Tu, Dinh Binh Chu

“…The excellent LOD and LOQ values of the developed method were achieved in the range of 0.5 to 2.9 μg·kg−1 and 1.7 to 9.6 μg·kg−1 for all species of arsenic, respectively. The ionization effect in plasma during chromatographic gradient elution was systematically investigated by using postcolumn injector. …”
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The Fate of the Interstellar Medium in Early-type Galaxies. V. Active Galactic Nucleus Feedback from Optical Spectral Classification by Oleh Ryzhov, Michał J. Michałowski, J. Nadolny, J. Hjorth, A. Leśniewska, M. Solar, P. Nowaczyk, C. Gall, T. T. Takeuchi

“…We use spectroscopic data and several physical parameters of 2409 dusty early-type galaxies in order to find out the dominant ionization source (active galactic nuclei, AGNs, young massive stars, hot low-mass evolved stars, HOLMES) and its effect on the ISM. …”
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Determination of Pharmaceutical Residues by UPLC-MS/MS Method: Validation and Application on Surface Water and Hospital Wastewater by Bui Van Hoi, Cam-Tu Vu, Lan-Anh Phung-Thi, Thao Thi Nguyen, Phuong Thanh Nguyen, Huong Mai, Phuong-Thu Le, Thanh-Hien Nguyen, Dao Thanh Duong, Hue Nguyen Thi, Dung Le-Van, Dinh Binh Chu

“…The method includes enrichment and clean-up steps by solid phase extraction using mix-mode cation exchange, followed by identification and quantification using an ultrahigh-performance liquid chromatography and tandem mass spectrometry and employing electrospray ionization (UPLC-ESI-MS/MS). Seven target compounds were separated on the reversed phase column and detected in multiple reaction monitoring (MRM) mode within 6 minutes. …”
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Identification of Plasma Absorbed Components of Qingxin Zishen Prescription by UPLC-Q-TOF MS by Yu HU, Juan SHANG, Xue-jiao LI, Yun-hua FENG, Kai-cheng XIE, Wei-feng YAO, Jian-dong ZOU, Yun CHEN, Su LU, Mei-juan XU

“…The MS and MS2 analysis were performed with the electrospray ionization (ESI) source under both positive and negative ion modes from m/z 100 to 1300. …”
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Identification and Mass Spectrometric Fragmentation Pathways of Chemical Components in the Traditional Chinese Medicine Formula of Jiuwei Decoction by Jia-yu ZHAO, Yue-guang LYU, Tong XIN, Qian-qian GUO, Wen-ying ZHANG, Jin-hong LI, Hong-yu XUE, Qiang MA

“…Before entering the quadrupole/Orbitrap high-resolution mass spectrometer for detection, samples underwent ionization under both positive and negative ion modes. …”
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Lyophilized and Oven-Dried <i>Manilkara zapota</i> Extracts: Characterization and <i>In Vitro</i>, <i>In Vivo</i>, and <i>In Silico</i> Analyses by María Fernanda Rivas-Gastélum, Patricia Ariadna Galindo-Castillo, Juan Esparza-Sánchez, Miriam Irene Jiménez-Pérez, Yocanxóchitl Perfecto-Avalos, Luis Eduardo Garcia-Amezquita, Diego E. Navarro-López, Edgar R. López-Mena, Eugenio Sánchez-Arreola, Juan Pablo Tamayo-Martínez, Humberto L. Mendoza-Figueroa, María Magdalena Crosby-Galván, Elsa Margarita Crosby-Galván, Jorge L. Mejía-Méndez, Angélica Lizeth Sánchez-López

“…The phytochemical content of fruits was assessed by gas chromatography flame ionization detector (GC-FID), and their biological performance was studied using <i>in vitro</i> antibacterial and antioxidant assays (DPPH and ABTS) and <i>in vivo</i> toxicity models. …”
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Multispecies pasture diet and cow breed affect the functional lipid profile of milk across lactation in a spring-calving dairy system by Renata Kostovska, Gaetan Drouin, Joaquín J. Salas, Mónica Venegas-Calerón, Brendan Horan, John T. Tobin, Tom F. O'Callaghan, Sean A. Hogan, Alan L. Kelly, Laura G. Gómez-Mascaraque

“…Changes in total fatty acid (FA) and triglyceride carbon number profiles were determined by GC with a flame ionization detector, and those in polar lipids (PL) content by HPLC–evaporative light scattering–MS. …”
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A UV to X-Ray View of Soft Excess in Type 1 Active Galactic Nuclei. I. Sample Selection and Spectral Profile by Shi-Jiang Chen, Jun-Xian Wang, Jia-Lai Kang, Wen-Yong Kang, Hao Sou, Teng Liu, Zhen-Yi Cai, Zhen-Bo Su

“…Remarkably, we show with simulations that a toy hybrid scenario, where both ionized disk reflection ( relxilllp , with all reflection parameters fixed at default values except for ionization of the disk) and warm corona ( compTT , with temperature fixed at 1 keV) contribute to the observed soft excess, can successfully reproduce the observed correlation. …”
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Understanding the Broad-line Region of Active Galactic Nuclei with Photoionization. I. The Moderate-accretion Regime by Qiaoya Wu, Yue Shen, Hengxiao Guo, Scott F. Anderson, W. N. Brandt, Catherine J. Grier, Patrick B. Hall, Luis C. Ho, Yasaman Homayouni, Keith Horne, Jennifer I-Hsiu Li, Donald P. Schneider

“…We provide quantitative recipes using optical/UV line flux ratios to infer the unobservable ionizing continuum. Additionally, photoionization models with universal values of ionization parameter ( $\mathrm{log}\,{U}_{{\rm{H}}}=-2$ ) and hydrogen density ( $\mathrm{log}\,n({\rm{H}})=12$ ) can qualitatively reproduce the observed global R – L relation for the current RM AGN sample. …”
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Chemical Composition Analysis of the Patented Naoxueshuan Formula Based on UPLC-Q-TOF MS and GC-MS by Chang LIU, Hui-qin WU, Jiang-bo QI, Hong-ling LIANG, Zhi-hua LIU, Hua-qiang HUANG, Su-ming YANG, Xi ZHOU, Fang HUANG, Hui-tai LUO

“…The GC-MS analysis was performed under programmed heating conditions with electron ionization (EI) as the ion source and a scanning mass range of m/z 50-550. …”
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JWST, ALMA, and Keck Spectroscopic Constraints on the UV Luminosity Functions at z ∼ 7–14: Clumpiness and Compactness of the Brightest Galaxies in the Early Universe by Yuichi Harikane, Akio K. Inoue, Richard S. Ellis, Masami Ouchi, Yurina Nakazato, Naoki Yoshida, Yoshiaki Ono, Fengwu Sun, Riku A. Sato, Giovanni Ferrami, Seiji Fujimoto, Nobunari Kashikawa, Derek J. McLeod, Pablo G. Pérez-González, Marcin Sawicki, Yuma Sugahara, Yi Xu, Satoshi Yamanaka, Adam C. Carnall, Fergus Cullen, James S. Dunlop, Eiichi Egami, Norman Grogin, Yuki Isobe, Anton M. Koekemoer, Nicolas Laporte, Chien-Hsiu Lee, Dan Magee, Hiroshi Matsuo, Yoshiki Matsuoka, Ken Mawatari, Kimihiko Nakajima, Minami Nakane, Yoichi Tamura, Hiroya Umeda, Hiroto Yanagisawa

“…At z ≳ 10, bright galaxies are classified into two types of galaxies: extended ones with weak high-ionization emission lines, and compact ones with strong high-ionization lines including N iv] λ 1486, indicating that at least two different processes (e.g., merger-induced starburst and compact star formation/AGN) are shaping the physical properties of the brightest galaxies at z ≳ 10 and are responsible for their overabundance.…”
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