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281
Phytochemicals of Vitis vinifera L. var. King Ruby protect mice from benzo(a)pyrene-induced lung injury
Published 2025-02-01“…King Ruby leaves methanol extract (VLME) was tentatively recognized by liquid chromatography electrospray ionization tandem mass spectrometric (LC-ESI-MS/MS). …”
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282
Epsilon Canis Majoris: The Brightest Extreme-ultraviolet Source with Surprisingly Low Interstellar Absorption
Published 2025-01-01“…The photoionization rate Γ _H ≈ (1–2) × 10 ^−14 s ^−1 at the cloud surface produces an ionization fraction (30%–40%) for total hydrogen density n _H = 0.2 cm ^−3 . …”
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283
Elevation of ganglioside degradation pathway drives GM2 and GM3 within amyloid plaques in a transgenic mouse model of Alzheimer's disease
Published 2025-02-01“…To address this gap, matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) was employed to investigate the age-dependent expression profiles of the A-series ganglioside species GD1a, GM1, GM2, and GM3 in the APP/PS1 transgenic mouse model of AD in which age-dependent amyloid-beta (Aβ) plaques develop. …”
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284
Biocontrol Potential of Rhizospheric Bacillus Strains Against <i>Sclerotinia minor</i> Jagger Causing Lettuce Drop
Published 2025-01-01“…Lipopeptide compounds produced by each strain were identified using matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI–TOF MS) analysis. …”
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285
Distribution and Antifungal Susceptibility Profile of Oropharyngeal Candida Species Isolated from People Living with HIV in the Era of Universal Test and Treat Policy in Uganda.
Published 2024“…Oropharyngeal swabs were collected and cultured on Sabouraud Dextrose agar to isolate Candida species identified using the matrix-assisted laser desorption ionization-time of flight mass spectrometry. Additionally, the antifungal susceptibility profile of Candida isolates to six antifungal drugs was determined using the VITEK® (Marcy-l’Étoile, France) compact system. …”
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286
Mass Fragmentation Characteristics of t-Boc Substituted Drug Precursors
Published 2025-01-01“…After analyzing the characteristic fragment ions under electron impact (EI) mode and electrospray ionization collision-induced dissociation (ESI-CID) mode, the possible fragmentation pathways of t-Boc substituted drug precursors were deduced. …”
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287
Ion suppression correction and normalization for non-targeted metabolomics
Published 2025-02-01“…We evaluate the method across ion chromatography (IC), hydrophilic interaction liquid chromatography (HILIC), and reversed-phase liquid chromatography (RPLC)-MS systems in both positive and negative ionization modes, with clean and unclean ion sources, and across different biological matrices. …”
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288
Phytochemical and Biological Investigations of Crude Extracts of <i>Astragalus pisidicus</i>
Published 2024-12-01“…<b>Methods</b>: The water and methanolic fractions of four parts (stems, flowers, leaves, root) as well as the whole plant were quantified and identified by Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry (LC–ESI–MS/MS) analysis. …”
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289
Anti-Inflammatory Activity of Diterpenoids from Celastrus orbiculatus in Lipopolysaccharide-Stimulated RAW264.7 Cells
Published 2020-01-01“…In this study, compounds 1–17, including undescribed podocarpane-type trinorditerpenoid (3), were purified from C. orbiculatus and their chemical structure were determined by high-resolution electrospray ionization mass (HRESIMS) and nuclear magnetic resonance (NMR) spectroscopic data. …”
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290
Simultaneous Determination of Multiple Acid-Suppressing Drugs by UPLC-MS/MS Method and Application for Pharmacokinetics Study
Published 2025-02-01“…Detection was performed on a triple quadrupole tandem mass spectrometer with positive electrospray ionization. Chromatographic separation was achieved on the ACQUITY UPLC BEH C18 column (2.1 × 50 mm, 1.7 μm) using gradient elution. …”
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291
UPLC-ESI-MS/MS Profile and Antioxidant, Cytotoxic, Antidiabetic, and Antiobesity Activities of the Aqueous Extracts of Three Different Hibiscus Species
Published 2020-01-01“…This inspired the authors to investigate the phytochemicals of these extracts for the first time using UPLC-ESI-MS/MS in negative and positive ionization modes. The analysis afforded the tentative identification of 103 compounds including phenolic compounds, flavonoids, and anthocyanins. …”
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292
Simultaneous Quantification of Pioglitazone and Omarigliptin in Rat Plasma by UHPLC-MS/MS and Its Application to Pharmacokinetic Study after Coadministration of the Two Drugs
Published 2021-01-01“…A multiple reaction monitor (MRM) was used under positive ionization mode with electrospray ion source to detect pioglitazone (357.1 ⟶ 134.1), omarigliptin (399.2 ⟶ 153.0), and sitagliptin (408.2 ⟶ 235.0). …”
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293
One-Step Solid Extraction for Simultaneous Determination of Eleven Commonly Used Anticancer Drugs and One Active Metabolite in Human Plasma by HPLC-MS/MS
Published 2018-01-01“…The Agilent G6410A triple quadrupole liquid chromatography-mass spectrometry system was operated under the multiple reaction monitoring mode with an electrospray ionization in the positive mode. Linear range was 25.0–2500.0 ng for paclitaxel, 10.0–1000.0 ng for docetaxel and SN-38, 100.0–10000.0 ng for vinorelbine and pemetrexed, 10.0–10000.0 ng for vinblastine and irinotecan, 1.0–1000.0 ng for cyclophosphamide and ifosfamide, 50.0–5000.0 ng for carboplatin, etoposide, and gemcitabine. …”
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294
Antibiotic Resistance and Molecular Epidemiological Characteristics of Streptococcus agalactiae Isolated from Pregnant Women in Guangzhou, South China
Published 2020-01-01“…Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) mass peak analysis was performed to discriminate the specific sequence types (STs). …”
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295
Proteomic Analysis of MCF-7 Breast Cancer Cell Line Exposed To Leptin
Published 2011-01-01“…Methods: We used two-dimensional gel electrophoresis (2-DE) and matrix assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) to identify proteins affected by leptin. …”
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296
Identification of Adulterated Deer Blood Crystals in Traditional Chinese Medicine Based on MALDI-TOF MS Peptide Fingerprints Technique
Published 2025-01-01“…A method based on matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) combined with chemometric blood analysis was established to identify adulteration in deer blood crystals used in traditional Chinese medicine. …”
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297
Organotin(IV) trifluoromethanesulfonate chemistry: isolation and characterization of novel 1,10-phenanthroline-based derivatives
Published 2024-05-01“…A possible structure, especially suggested by electrospray-ionization mass spectrometry, is proposed as [{n-Bu2Sn(phen)(CF3SO3)}2(µ-CF3SO3)][CF3SO3]. …”
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298
Temporal changes in plasma and milk lipids in response to an esophageal bolus of rumen-protected fish oil in lactating Holstein dairy cows
Published 2025-02-01“…Separated milk fat was analyzed for individual milk FA using gas–liquid chromatography and a flame-ionization detector. Data were analyzed under a mixed model with the random effect of cow, and the fixed effects of treatment, hour, and period. …”
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299
Isolation and characterization of novel peptides from fermented products of Lactobacillus for ulcerative colitis prevention and treatment
Published 2022-11-01“…Herein, 4 novel peptides are identified from AC-WGAF by membrane ultrafiltration, recycling preparative high-performance liquid chromatography, and matrix-assisted laser desorption–ionization time-of-flight/time-of-flight mass spectrometry, possessing anti-colitis activity via using an in vitro model. …”
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300
Salvia deserti Decne., an endemic and rare subshrub from Arabian desert: antidiabetic and antihyperlipidemic effects of leaf hydroethanolic extracts
Published 2025-02-01“…The identity of phenolic compounds of the hydroethanolic extract of S. deserti was conducted through HPLC-Electrospray Ionization-Mass Spectrometry (LC-ESI-MS) analyses.ResultsOral administration of hydroethanolic extract of S. deserti at 200 and 400 mg/kg for 14 days significantly decreased blood glucose and restored the hepatic and renal function by reducing the levels of ALT, AST, ALP, GGT, LDH, urea and creatinine. …”
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