LC-MS/MS Method for Simultaneous Quantification of Dexmedetomidine, Dezocine, and Midazolam in Rat Plasma and Its Application to Their Pharmacokinetic Study by Wenjuan Cui, Qin Liu, Shan Xiong, Lujun Qiao

“…The analytes were determined with selected reaction monitoring under positive ionization mode. The intra- and interday precision and accuracy were all within acceptable limits during the entire validation, and the stability of analytes was acceptable under various storage conditions. …”
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Analytical Method Development and Validation for the Quantification of Acetone and Isopropyl Alcohol in the Tartaric Acid Base Pellets of Dipyridamole Modified Release Capsules by... by Sriram Valavala, Nareshvarma Seelam, Subbaiah Tondepu, V. Shanmukha Kumar Jagarlapudi, Vivekanandan Sundarmurthy

“…The method was developed and optimized by using fused silica DB-624 (30 m × 0.32 mm × 1.8 µm) column with the flame ionization detector. The method validation was carried out with regard to the guidelines for validation of analytical procedures Q2 demanded by the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH). …”
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Performance of the VITEK® MS system for the identification of filamentous fungi in a microbiological laboratory in Chile. by Lorena Porte, Rodrigo Cruz, Inia Pérez, Carmen Varela, Cristina Díaz, Patricia García, Paulette Legarraga, Francisca Valdivieso, Thomas Weitzel

“…Matrix-assisted laser desorption/ionization-time-of-flight (MALDI-TOF) mass spectrometry is a rapid and easy-to-perform identification method. …”
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Long-Term Stability of Hydromorphone in Human Plasma Frozen at −20°C for Three Years Quantified by LC-MS/MS by Andreas Wehrfritz, Stefanie Schmidt, Harald Ihmsen, Jürgen Schüttler, Christian Jeleazcov

“…Hydromorphone concentrations were determined by ultra-performance liquid chromatography (UPLC) with gradient elution, followed by tandem mass spectrometry with electrospray ionization. Calibration curves demonstrated linearity of the assay in the concentration range of 0.3–20 ng/mL hydromorphone. …”
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The effect of temperature factor during heavy ion irradiation on structural disordering of SiC ceramics by Kymbat M. Tynyshbayeva, Artem L. Kozlovskiy

“…In turn, the combination of the effects of thermal heating and ionization processes causes deformation distortion of chemical bonds, which is most pronounced at high irradiation temperatures, for which thermal expansion of the crystal lattice and accelerated diffusion of vacancy defects play a key role in disordering.…”
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METROLOGICAL SUPPORT OF DOSIMETRY GAMMA-RAY WITH ENERGY TO 10 MEV FOR RADIATION PROTECTION DEVICES by D. I. Komar, R. V. Lukashevich, V. D. Guzov, S. A. Kutsen

“…The aim of this work was to determine the metrological characteristics of capture gamma-ray fields from titanium target and nickel target obtained at the AT140 Neutron Calibration Facility to provide dosimetry up to 10 MeV.We have chosen energy intervals in which we can calibrate dosimetry devices taking into account the accompanying generation of gamma-ray neutrons by the fast neutron source 238PuBe, the capture radiation of collimator materials and capture radiation from targets.We measured air kerma rate with the aid of the reference AT5350 dosimeter with the ionization chamber TM32002. Using the Monte-Carlo simulation, we obtained the energy distribution of the air kerma rate for targets. …”
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Advanced LC-MS/MS method for selective quantification of nitrosamine impurities in Risperidone: Enhancing drug safety by Hitesh Thumbar, Pankajkumar Nariya, Bhavin Dhaduk

“…Positive electrospray ionization (ESI) in multiple reaction monitoring (MRM) mode was used for quantification. …”
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Statistical Characterization of GITM Thermospheric Horizontal Winds in Comparison to GOCE Estimations by Daniel A. Brandt, Aaron J. Ridley

“…Comparisons between cross‐track horizontal winds from a 10‐month run of Global Ionosphere‐Thermosphere (GITM) and those derived from the Gravity field and steady‐state Ocean Circulation Explorer (GOCE) satellite show that GITM did best modeling horizontal winds in the polar zone but overestimated horizontal wind speeds at midlatitudes just outside of the equatorial ionization anomaly region. GITM's wind response to AE was best at polar noon and worst in the midnight auroral zone, its ability to capture seasonality was best in the northern high latitudes and worst in the southern high latitudes, and GITM displayed less wind variability as a function of F10.7 than GOCE, matching it best for F10.7 >∼150. …”
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Study of Grape Polyphenols by Liquid Chromatography-High-Resolution Mass Spectrometry (UHPLC/QTOF) and Suspect Screening Analysis by Riccardo Flamini, Mirko De Rosso, Luigi Bavaresco

“…The method allows identification of several hundred grape metabolites with two analyses (positive and negative ionization modes), and performing of data reprocessing using “untargeted” algorithms also provided the identification of some flavonols and resveratrol trimers and tetramers in grape for the first time. …”
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UHPLC‐Q‐TOF‐MS/MS Dereplication to Identify Chemical Constituents of Hedera helix Leaves in Vietnam by Hong Ngoc Pham, Chieu An Tran, Thi Diep Trinh, Ngoc Lan Nguyen Thi, Huynh Nhu Tran Phan, Van Nhan Le, Ngoc Hung Le, Van Trung Phung

“…MS, and MS/MS experiments were manipulated using both negative and positive ionization modes to provide molecular mass information and production spectra for the structural elucidation of compounds. …”
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Microwave assisted palladium catalyzed carbon-carbon bond formation to synthesise novel benzimidazole derivatives and their Photophysical properties, molecular docking, and DFT stu... by Vijayabharathi Sundharaj, S. Sarveswari

“…These calculations aimed to predict the chemical reactivity of the newly synthesized benzimidazole derivatives by assessing parameters such as the HOMO-LUMO energy gap value, ionization potential, electrostaic potential, electron affinity, electronegativity, global hardness, and softness energy values. …”
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An Optimized High Throughput Clean-Up Method Using Mixed-Mode SPE Plate for the Analysis of Free Arachidonic Acid in Plasma by LC-MS/MS by Wan Wang, Suzi Qin, Linsen Li, Xiaohua Chen, Qunjie Wang, Junfu Wei

“…The collected fraction was injected onto a reversed phase column at 30°C with mobile phase of acetonitrile/water (70 : 30, v/v) and detected by LC-MS/MS coupled with electrospray ionization (ESI) in multiple reaction monitoring (MRM) mode. …”
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Dibohemamines I–O from Streptomyces sp. GZWMJZ-662, an endophytic actinomycete from the medicinal and edible plant Houttuynia cordata Thunb. by Dong-Yang Wang, Ming-Xing Li, Yan-Chao Xu, Peng Fu, Wei-Ming Zhu, Li-Ping Wang

“…Their structures were elucidated through detailed spectroscopic analysis, encompassing high-resolution electrospray ionization mass, nuclear magnetic resonance, infrared radiation, ultraviolet–visible, and electronic circular dichroism spectroscopy. …”
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Biosensitivity and Theoretical Electronic Structure Investigations on 3-(2-Hydroxyphenyl)-2-iminothiazolidin-4-one and Its Zn2+ and Cd2+ Metal Complexes by Zewdu Bezu Gemechu, Boobalan Maria Susai, Abi M. Taddesse, Endale Teju Bedada, R. Ramamoorthy

“…Other theoretical properties such as hardness, softness, electron affinities, and ionization potential were derived and discussed in detail.…”
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A Novel Spectrometer for Measuring Laser-Produced Plasma X-Ray in Inertial Confinement Fusion by Zhu Gang, Xiong Xian-cai, Zhong Xian-xin, Yang Yan

“…In the experimental investigations of inertial confinement fusion, the laser-produced high-temperature plasma contains very abundant information, such as the electron temperature and density, ionization. In order to diagnose laser-plasma distribution in space and evolution in time, an elliptical curved crystal spectrometer has been developed and applied to diagnose X-ray of laser-produced plasma in 0.2~2.46 nm region. …”
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Self-Assemblies of Single-Walled Carbon Nanotubes through Tunable Tethering of Pyrenes by Dextrin for Rapidly Chiral Sensing by Wei-Li Wei, Qiushui Chen, Haifang Li, Jin-Ming Lin

“…Py-Dex and Py-Dex-SWNTs were adequately characterized by NMR, UV-vis, fluorescence spectroscopy, Raman spectroscopy, matrix-assisted laser desorption/ionization-time of flight mass spectroscopy, and transmission electron microscopy. …”
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The Addition of Tomato and Spinach Powder to Semolina Pasta: A Study of the Impact of the Production Process and Cooking on Phenolic Compounds by Silvia Marzocchi, Federica Pasini, Renzo Santi, Maria Fiorenza Caboni

“…High-performance liquid chromatography–electrospray ionization triple quadrupole mass spectrometry (HPLC-ESI-QqQ-MS) was employed to analyse the free and bound phenolic content in the raw materials, as well as in both dried uncooked and cooked pasta. …”
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Sweat Cortisol and Cortisone Determination in Healthy Adults: UHPLC-MS/MS Assay Validation and Clinical Application by Syed N. Alvi, Kafa Abuhdeeb, Muhammad M. Hammami

“…A positive electrospray ionization interface with multiple-reaction monitoring mode was used to provide simultaneous quantification of cortisol, cortisone, and internal standard at transitions of 363.11 to 121.00, 361.18 to 163.11, and 367.19 to 121.24, respectively. …”
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Protein Glycation in Diabetes as Determined by Mass Spectrometry by Annunziata Lapolla, Laura Molin, Pietro Traldi

“…This paper reports and discusses some of the data pertaining protein glycation in diabetic subjects obtained by matrix-assisted laser desorption ionization (MALDI) mass spectrometry (MS). The preliminary studies carried out by in vitro protein glycation experiments show clear differences in molecular weight of glycated and unglycated proteins. …”
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Low Dose Rate X-Ray Radiation Fields Implementation for Study of Energy Response of the Dosimeters Based on Scintillation Detectors by A. V. Novichenko, R. V. Lukashevich, K. G. Senkovsky

“…To verify comparators energy response the reference AT5350/1 dosimeter and ionization chamber TM32003 with sensitive volume 10000 cm3 were used.Characteristics of X-ray fields that were created on the AT300 X-ray calibration facility to verify the energy response of high sensitive dosimeters based on scintillation detectors were investigated. …”
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