The crystal structure of [1-(4-(trifluoromethyl)phenyl)-3,4-dihydroquinolin-2(1H)-one], C16H12F3NO by Pu Xuewei, Meng Fanjie, Zhang Shaoliang

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Synthesis and Characterization of 9-Phenyl-9H-purin-6-amines from 5-Amino-1-phenyl-1H-imidazole-4-carbonitriles by Asieh Yahyazadeh, Fatemah Habibi

“…9-Phenyl-9H-purin-6-amine derivatives have been synthesized in high yields by reaction between 5-amino-1-phenyl-1H-imidazole-4-carbonitrile with HC(OEt)3 and Ac2O followed by reaction with ammonia.…”
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Shrimp White Spot Viral Infections Are Attenuated by Organic Acids by Regulating the Expression of HO-1 Oxygenase and β-1,3-Glucan-Binding Protein by Ioan Pet, Igori Balta, Nicolae Corcionivoschi, Tiberiu Iancu, Ducu Stef, Lavinia Stef, Iuliana Cretescu

“…In vivo, in a shrimp challenge test, 2% Aq significantly downregulated the expression of proteins involved in WSSV virulence, such as the lipopolysaccharide-β-1,3-glucan-binding protein (LGBP) and the TLR signalling pathway (LvECSIT), and increased the expression of HO-1 oxygenase. …”
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Low Self-Confidence and Diabetes Mismanagement in Youth with Type 1 Diabetes Mediate the Relationship between Behavioral Problems and Elevated HbA1c by Minke M. A. Eilander, Maartje de Wit, Joost Rotteveel, Frank J. Snoek

“…Previous studies indicated an association between behavior problems (internalizing, externalizing) and glycemic control (HbA1c) in youth with type 1 diabetes (T1D). The aim of this study is to examine if this association is mediated by self-confidence and mismanagement of diabetes. …”
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A tags’ arrival rate estimation method using weighted grey model(1,1) and sliding window in mobile radio frequency identification systems by Liqian Zhang, Xueliang Fu, Honghui Li

“…Using sliding window mechanism and weighted coefficients method, weighted grey model(1,1) with sliding window (WGMSW(1,1)) is proposed based on traditional grey model(1,1). …”
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Influenza Infection Screening Tools Fail to Accurately Predict Influenza Status for Hospitalized Patients During Pandemic H1N1 Influenza Season by Sunita Mulpuru, Virginia R Roth, Nadine Lawrence, Alan J Forster

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Author Correction: MT1G promotes iron autophagy and inhibits the function of gastric cancer cell lines by intervening in GPX4/SQSTM1 by Kaiqiang Meng, Jian Song, Fan Qi, Jiamin Li, Zhichao Fang, Liang Song

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Chemopreventative potential of Salsola tuberculatiformis Botch and Compound A in the differential regulation of IL-1Ra:IL-1α in UVB exposed skin keratinocytes by T. Magcwebeba, L. McEvoy, S. Hayward, T. Tait, J.L Quanson, L. Kelbe, WCA Gelderblom, M. Lilly, A.C Swart, P. Swart

“…Anti/pro-inflammatory effects were evaluated by measuring IL-1α and IL-1Ra production using an ELISA assay. …”
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Interaction Between Malat1 and miR-499-5p Regulates Meis1 Expression and Function with a Net Impact on Cell Proliferation by Salma A. Fahim, Manon Ragheb, Ibrahim Hassan Fayed, Aya Osama, Ahmed Karam, Sameh Magdeldin, Rana Metwale, Mohamed Dief Allah Abdalmoneam Elsayed, Ahmed Abdellatif, Hesham A. Sadek, Shereen Ahmed El Sobky, Nada El-Ekiaby, Injie Omar Fawzy, Ahmed Ihab Abdelaziz

Subjects: “…Meis1…”
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LRH‐1/NR5A2 targets mitochondrial dynamics to reprogram type 1 diabetes macrophages and dendritic cells into an immune tolerance phenotype by Nadia Cobo‐Vuilleumier, Silvia Rodríguez‐Fernandez, Livia López‐Noriega, Petra I. Lorenzo, Jaime M. Franco, Christian C. Lachaud, Eugenia Martin Vazquez, Raquel Araujo Legido, Akaitz Dorronsoro, Raul López‐Férnandez‐Sobrino, Beatriz Fernández‐Santos, Carmen Espejo Serrano, Daniel Salas‐Lloret, Nila vanOverbeek, Mireia Ramos‐Rodriguez, Carmen Mateo‐Rodríguez, Lucia Hidalgo, Sandra Marin‐Canas, Rita Nano, Ana I. Arroba, Antonio Campos Caro, Alfred CO Vertegaal, Alejandro Martín‐Montalvo, Franz Martín, Manuel Aguilar‐Diosdado, Lorenzo Piemonti, Lorenzo Pasquali, Roman González Prieto, Maria Isabel García Sánchez, Decio L. Eizirik, Maria Asuncion Martínez‐Brocca, Marta Vives‐Pi, Benoit R. Gauthier

“…Abstract Background The complex aetiology of type 1 diabetes (T1D), characterised by a detrimental cross‐talk between the immune system and insulin‐producing beta cells, has hindered the development of effective disease‐modifying therapies. …”
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Microglia TRPC1 SUMOylation drives neuroinflammation after stroke by modulating NLRP3 activity via increasing TRPC1 interaction with ARRB2 by Huinan Zhang, Xinzhe Du, Tian Gao, Xing Wang, Huifeng Zhang, Manyang Yu, Jing Huang

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B(HSO4)3 as an Efficient Catalyst for the Syntheses of Bis(1H -Indol-3-yl)ethanones and Bis(benzotriazol-1-yl)ethanones by Mohammad Hossein Mosslemin, Abolfazl Eshghi Movahhed

“…Efficient syntheses of bis (1H-indol-3-yl)ethanones and bis (benzotriazolyl)ethanones via reaction of phenylglyoxals with indole or 1,H-benzotriazole in the presence B(HSO4)3 in solvent-free thermal and in aqueous media conditions are discribed. …”
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The crystal structure of (1E,2E)-1,2-bis(quinolin-2-ylmethylene)hydrazine, C20H14N4 by Liao Fuguang, Yuan Shuhao, Nie Weifeng, Yi Zirong, Zhang Qian, Yan Shiyu, Cui Ying

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NUAK1 acts as a novel regulator of PD-L1 via activating GSK-3β/β-catenin pathway in hepatocellular carcinoma by Chao-Yan Yao, Hang-Tian Tao, Jin-Jin He, Feng-Yi Zhu, Cui-Qing Xie, Yu-Na Cheng, Ji-Qin Li, Zhuang-Zhuang Liu, Chun-Yu Hou, Xue-Li Liu, Yong-Li Fan, Dong Fang, Xin-Rui Lv

Subjects: “…NUAK1…”
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Altered AKT1 and MAPK1 Gene Expression on Peripheral Blood Mononuclear Cells and Correlation with T-Helper-Transcription Factors in Systemic Lupus Erythematosus Patients by Sonia Garcia-Rodriguez, Jose-Luis Callejas-Rubio, Norberto Ortego-Centeno, Esther Zumaquero, Raquel Ríos-Fernandez, Salvador Arias-Santiago, Pilar Navarro, Jaime Sancho, Mercedes Zubiaur

“…Kinases have been implicated in the immunopathological mechanisms of Systemic Lupus Erythematosus (SLE). v-akt murine-thymoma viral-oncogene-homolog 1 (AKT1) and mitogen-activated-protein-kinase 1 (MAPK1) gene expressions in peripheral mononuclear cells from thirteen SLE patients with inactive or mild disease were evaluated using quantitative real-time reverse-transcription polymerase-chain-reaction and analyzed whether there was any correlation with T-helper (Th) transcription factors (TF) gene expression, cytokines, and S100A8/S100A9-(Calprotectin). …”
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A new crustin-like gene from the redclaw crayfish Cherax quadricarinatus and its response to decapod iridescent virus 1 (DIV1) challenge by Xiaoying Hang, Jianbo Zheng, Fei Li

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SLC31A1 promotes chemoresistance through inducing CPT1A-mediated fatty acid oxidation in ER-positive breast cancer by Xudong Li, Jingjing Ge, Mengdi Wan, Tongtong Feng, Xiaoqian Li, Haibo Zhang, Zhangyan Wang, Yongsheng Gao, Meiting Chen, Fei Pan

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Disrupting EDEM3‐induced M2‐like macrophage trafficking by glucose restriction overcomes resistance to PD‐1/PD‐L1 blockade by Shaoyong Peng, Minshan Wu, Qian Yan, Gaopo Xu, Yumo Xie, Guannan Tang, Jinxin Lin, Zixu Yuan, Xiaoxia Liang, Ze Yuan, Jingrong Weng, Liangliang Bai, Xiaolin Wang, Huichuan Yu, Meijin Huang, Yanxin Luo, Xiaoxia Liu

“…However, the EDEM3‐mediated upregulation of PD‐L1 expression underpins PD‐1/PD‐L1 blockade resistance in vivo. …”
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Synthesis, Characterisation, Theoretical NMR Calculations and Crystal Structure of the 3-methyl-1H-1,2,4?4-triazole-5-amine acetate by Patricia Saraiva Vilas Boas Almeida, José Roberto da Silveira Maia, Márcia Cristina de Souza, Alison Geraldo Pacheco

Subjects: “…1,2,4-Triazole compounds. Biological assay. Crystal structure. …”
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Microwave-Induced, Iodine-Alumina Catalyzed Transformations of 1-(2′-hydroxyaryl)-3-(2-chloroquinolin-3-yl)-prop-2-en-1-one by P. Venkatesan, K. Moorthi

“…The chalcone derivatives, 1-(2′-hydroxyaryl)-3-(2-chloroquinolin-3-yl)-prop-2-en-1-one was transformed to corresponding flavone derivatives by iodine impregnated neutral alumina under microwave irradiation. …”
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