Macrophages facilitate tumor cell PD‐L1 expression via an IL‐1β‐centered loop to attenuate immune checkpoint blockade by Cheng Xu, Yu Xia, Bai‐Wei Zhang, Emmanuel Kwateng Drokow, Hua‐Yi Li, Sen Xu, Zhen Wang, Si‐Yuan Wang, Ping Jin, Tian Fang, Xiao‐Ming Xiong, Pu Huang, Ning Jin, Jia‐Hong Tan, Qing Zhong, Yu‐Xin Chen, Qi Zhang, Yong Fang, Fei Ye, Qing‐Lei Gao

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Efficacy of PD-1/PD-L1 Inhibitors versus Chemotherapy in Lung Cancer with Brain Metastases: A Systematic Review and Meta-Analysis by Xiaojun Yang, Yihong Zeng, Qinquan Tan, Zhihua Huang, Jun Jia, Guanming Jiang

“…This study aimed to evaluate the efficacy of PD-1/PD-L1 ICIs compared with chemotherapy for patients with lung cancer with BM. …”
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HEADING TIME OF SUBSTITUTION AND NEAR-ISOGENIC LINES OF COMMON WHEAT WITH DOMINANT ALLELES Vrn-B1a AND Vrn-B1c by M. V. Emtseva, T. T. Efremova, V. S. Arbuzova

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In silico analysis of SNPs and miRNAs of KCTD13, CSDE1, SLC6A1 genes associated with autism spectrum disorder by Kübra Çoruh Kınalı, Ebru Özkan Oktay, Mesut Karahan

“…The objective of this study is to utilize in silico tools to predict the possible damaging impacts of SNPs (missense) in ASD-related KCTD13, CSDE1, and SLC6A1 genes that cause amino acid substitution on protein function, stability, structure, and miRNA target binding sites. …”
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The PD-1 with PD-L1 Axis Is Pertinent with the Immune Modulation of Atrial Fibrillation by Regulating T Cell Excitation and Promoting the Secretion of Inflammatory Factors by Guodong Chang, Yingwei Chen, Zichang Liu, Yong Wang, Wenkun Ge, Yongan Kang, Shuling Guo

“…To analyze the role of PD-1/PD-L1 signaling pathway in regulating T cell activation and secretion of proinflammatory factors in atrial fibrillation. …”
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HSV-1 miR-H6 Inhibits HSV-1 Replication and IL-6 Expression in Human Corneal Epithelial Cells In Vitro by Fang Duan, Jingyu Liao, Qiang Huang, Yuhong Nie, Kaili Wu

“…HSV-1 infection in the cornea could lead to blindness. …”
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Arabidopsis conditional photosynthesis mutants abc1k1 and var2 accumulate partially processed thylakoid preproteins and are defective in chloroplast biogenesis by Joy Collombat, Manfredo Quadroni, Véronique Douet, Rosa Pipitone, Fiamma Longoni, Felix Kessler

“…In this study we used 680 nm red light to overexcite Photosystem II and disrupt photosynthesis in two conditional mutants (var2 and abc1k1) which reversibly arrested chloroplast biogenesis. …”
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Integrated Management of Cardiovascular–Renal–Hepatic–Metabolic Syndrome: Expanding Roles of SGLT2is, GLP-1RAs, and GIP/GLP-1RAs by Nikolaos Theodorakis, Maria Nikolaou

“…This review addresses the following critical question: How can novel anti-diabetic agents, including sodium–glucose cotransporter-2 inhibitors (SGLT2is), glucagon-like peptide-1 receptor agonists (GLP-1RAs), and dual gastric inhibitory polypeptide (GIP)/GLP-1RA, offer an integrated approach to managing CRHM syndrome beyond the boundaries of traditional specialties? …”
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Uncovering the role of tumor cGAS expression in predicting response to PD-1/L1 inhibitors in non-small cell lung cancer by Yuichi Ozawa, Yasuhiro Koh, Ryota Shibaki, Yuhei Harutani, Hiroaki Akamatsu, Atsushi Hayata, Takeya Sugimoto, Yuka Kitamura, Junya Fukuoka, Masanori Nakanishi, Nobuyuki Yamamoto

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On the Solutions of the System of Difference Equations xn+1=max{A/xn,yn/xn}, yn+1=max{A/yn,xn/yn} by Dağistan Simsek, Bilal Demir, Cengiz Cinar

“…We study the behavior of the solutions of the following system of difference equations xn+1=max⁡{A/xn,yn/xn}, yn+1=max⁡{A/yn,xn/yn} where the constant A and the initial conditions are positive real numbers.…”
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Differential expression and upregulation of interleukin-1α, interleukin-1β and interleukin-6 by freshly isolated human small intestinal epithelial cells by Laura Madrigal-Estebas, Derek G. Doherty, Diarmuid P. O'Donoghue, Conleth Feighery, Cliona O'Farrelly

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Analytical Performances of Human Immunodeficiency Virus Type 1 RNA-Based Amplix® Real-Time PCR Platform for HIV-1 RNA Quantification by Christian Diamant Mossoro-Kpinde, Ralph-Sydney Mboumba Bouassa, Mohammad-Ali Jenabian, Serge Tonen Wolyec, Leman Robin, Mathieu Matta, Jean de Dieu Longo, Gérard Grésenguet, Laurent Andreoletti, Laurent Bélec

“…We evaluated the performances of Amplix real-time PCR platform developed by Biosynex (Strasbourg, France), combining automated station extraction (Amplix station 16 Dx) and real-time PCR (Amplix NG), for quantifying plasma HIV-1 RNA by lyophilized HIV-1 RNA-based Amplix reagents targeting gag and LTR, using samples from HIV-1-infected adults from Central African Republic. …”
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Haack, Susan. "La fragmentación de la filosofía, el camino a la reintegración." ἔλεγχος 1.1 (2016): 7-48. by CARLOS G. PATARROYO G

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Incompletely closed HIV-1CH040 envelope glycoproteins resist broadly neutralizing antibodies while mediating efficient HIV-1 entry by Durgadevi Parthasarathy, Stephanie Pickthorn, Shamim Ahmed, Dmitry Mazurov, Jeffy Jeffy, Rajni Kant Shukla, Amit Sharma, Alon Herschhorn

“…Abstract HIV-1 envelope glycoproteins (Envs) mediate viral entry and are sole target of neutralizing antibodies. …”
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New Investigation of Millimeter-Wave Rotational Spectrum of CF3CN in the Excited Vibrational States v7=1 and v8=1 by Masoud Motamedi, Bahram Vahabzadeh Zargari

“…The millimeter-wave rotational spectra of the excited vibrational states v7=1 and v8=1 of the symmetric top molecule trifluoroacetonitrile, CF3CN, have been analyzed again. …”
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Placenta-derived mesenchymal stem cells protect against diabetic kidney disease by upregulating autophagy-mediated SIRT1/FOXO1 pathway by Honghong Liu, Jiao Wang, Guanru Yue, Jixiong Xu

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Unveiling the signal valve specifically tuning the TGF-β1 suppression of osteogenesis: mediation through a SMAD1-SMAD2 complex by Ying-Wen Wang, Ching-Wei Luo

Subjects: “…TGF-β1…”
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Distribution of (1,3)(1,4)-β-D-Glucans in Grains of Polish Oat Cultivars and Lines (Avena sativa L.) – Short Report by Sykut-Domańska Emilia, Rzedzicki Zbigniew, Zarzycki Piotr, Sobota Aldona, Błaszczak Wioletta

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Differences in immune-related toxicity between PD-1 and PD-L1 inhibitors: a retrospective cohort study in patients with advanced cancer by Cecilia Olsson Ladjevardi, Marcus Skribek, Anthoula Koliadi, Viktoria Rydén, Ali Inan El-Naggar, Evangelos Digkas, Antonios Valachis, Gustav J. Ullenhag

Subjects: “…PD-1 inhibitors…”
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Heterologous cAd3-Ebola and MVA-EbolaZ vaccines are safe and immunogenic in US and Uganda phase 1/1b trials by Myra Happe, Amelia R. Hofstetter, Jing Wang, Galina V. Yamshchikov, LaSonji A. Holman, Laura Novik, Larisa Strom, Francis Kiweewa, Salim Wakabi, Monica Millard, Colleen F. Kelley, Sarah Kabbani, Srilatha Edupuganti, Allison Beck, Florence Kaltovich, Tamar Murray, Susanna Tsukerman, Derick Carr, Carl Ashman, Daphne A. Stanley, Aurélie Ploquin, Robert T. Bailer, Richard Schwartz, Fatim Cham, Allan Tindikahwa, Zonghui Hu, Ingelise J. Gordon, Nadine Rouphael, Katherine V. Houser, Emily E. Coates, Barney S. Graham, Richard A. Koup, John R. Mascola, Nancy J. Sullivan, Merlin L. Robb, Julie A. Ake, Kirsten E. Lyke, Mark J. Mulligan, Julie E. Ledgerwood, Hannah Kibuuka, the VRC 208 and RV 422 study team

“…We investigated the safety and immunogenicity of a heterologous prime-boost regimen involving a chimpanzee adenovirus 3 vectored Ebola vaccine [either monovalent (cAd3-EBOZ) or bivalent (cAd3-EBO)] prime followed by a recombinant modified vaccinia virus Ankara EBOV vaccine (MVA-EbolaZ) boost in two phase 1/1b randomized open-label clinical trials in healthy adults in the United States (US) and Uganda (UG). …”
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