Molecular, Biochemical, and Clinical Characterization of Thirteen Patients with Glycogen Storage Disease 1a in Malaysia by Siti Aishah Abdul Wahab, Yusnita Yakob, Mohd Khairul Nizam Mohd Khalid, Noraishah Ali, Huey Yin Leong, Lock Hock Ngu

“…Glycogen storage disease type 1a (GSD1a) is a rare autosomal recessive metabolic disorder characterized by hypoglycaemia, growth retardation, lactic acidosis, hepatomegaly, hyperlipidemia, and nephromegaly. …”
Get full text

Normative Data for Bone Mass in Healthy Term Infants from Birth to 1 Year of Age by Sina Gallo, Catherine A. Vanstone, Hope A. Weiler

“…During the year, WB BMC increased by 200% (76.0±14.2 versus 227.0±29.7 g), spine BMC by 130% (2.35±0.42 versus 5.37±1.02 g), and femur BMC by 190% (2.94±0.54 versus 8.50±1.84 g). …”
Get full text

The interaction of tPA with NMDAR1 drives neuroinflammation and neurodegeneration in α-synuclein-mediated neurotoxicity by Daniel Torrente, Enming J. Su, Alí Francisco Citalán-Madrid, Gerald P. Schielke, Daniel Magaoay, Mark Warnock, Tamara Stevenson, Kris Mann, Flavie Lesept, Nathalie Delétage, Manuel Blanc, Erin H. Norris, Denis Vivien, Daniel A. Lawrence

“…Finally, treatment of mice with glunomab, a neutralizing antibody that selectively blocks tPA binding to the N-methyl-D-aspartate receptor-1 (NMDAR1) without affecting NMDAR1 ion channel function, identifies the tPA interaction with NMDAR1 as necessary for tPA-mediated neuroinflammation and neurodegeneration in response to α-synuclein-mediated neurotoxicity. …”
Get full text

Anti-Bacterial evaluation of 1,3-Benzodioxole derived imidazolium and pyridinium based ionic liquids by Sagar Panchal, Hitesh Sehrawat, Nisha Yadav, Shipra Chandra, Vivek Mishra, Neera Sharma, Ramesh Chandra

Subjects: “…1,3-benzodioxol…”
Get full text

Editorial: Impact of the innate and adaptive immune system in driving type 1 inflammatory skin disease by Mark Mellett, Judit Danis, Barbara Meier-Schiesser

Subjects: Get full text

Physicochemical Studies of Some Schiff Bases Derived From 6-Ethylbenzene 1,3-diol by Shipra Baluja

Get full text

Novel Copy Number Deletion Involving NUS1 Associated With Epilepsy, Tremor, and Intellectual Disability by Jing Y. Hsu, Daniah H. Ibrahim, Riza Ali, Elaine Marchi, Maureen Gavin, Karen Amble, Gholson J. Lyon

Subjects: Get full text

High antimony resistance strain Enterobacter sp. Z1 mediates biomineralization of antimony trioxide by Zijie Zhou, Hongbo Yu, Gejiao Wang, Mingshun Li, Kaixiang Shi

“…Furthermore, Enterobacter sp. Z1 produced antimony trioxide (Sb2O3) via biomineralization during cultivation. …”
Get full text

High Frequency of AIFM1 Variants and Phenotype Progression of Auditory Neuropathy in a Chinese Population by Hongyang Wang, Dan Bing, Jin Li, Linyi Xie, Fen Xiong, Lan Lan, Dayong Wang, Jing Guan, Qiuju Wang

“…Of the 50 AN patients with AIFM1 variants, 45 were male and 5 were female. The hotspot variation of this gene was p.Leu344Phe, accounting for 36.1%. …”
Get full text

Meta-analysis of the accuracy for RASSF1A methylation in bronchial aspirates for the diagnosis of lung cancer. by Xu-Ping Chen, Shi-Xu He, Meng-You Chen, Fu-Bin Chen, Peng Wu, Ping Shi, Shi-Cai Zhao, Ling-Yan Zhao, Xiao-Min Xiong, Jia Zeng

“…<h4>Objective</h4>To establish the diagnostic accuracy of RASSF1A (Ras association domain family 1 isoform) methylation using bronchial aspirates as an auxiliary method for diagnosing lung cancer through a systematic review and meta-analysis.…”
Get full text

Changes in the Physiological Parameters of SbPIP1-Transformed Wheat Plants under Salt Stress by G. H. Yu, X. Zhang, H. X. Ma

“…In order to understand the physiological responses in plants that are mediated by the SbPIP1 gene, SbPIP1-overexpressing wheat lines and WT plants of the wheat cv. …”
Get full text

Notch1 Signaling Regulates the Th17/Treg Immune Imbalance in Patients with Psoriasis Vulgaris by Lei Ma, HaiBo Xue, Tianqin Gao, MeiLan Gao, YuJie Zhang

“…To evaluate the regulating effect of Notch1 signaling on Th17/Treg immune imbalance in psoriasis vulgaris (PV). …”
Get full text

Targeting SRSF1 improves cancer immunotherapy by dually acting on CD8+T and tumor cells by Gui-Qi Zhu, Zheng Tang, Tian-Hao Chu, Biao Wang, Shi-Ping Chen, Chen-Yang Tao, Jia-Liang Cai, Rui Yang, Wei-Feng Qu, Yi Wang, Qian-Fu Zhao, Run Huang, Meng-Xin Tian, Yuan Fang, Jun Gao, Xiao-Ling Wu, Jian Zhou, Wei-Ren Liu, Zhi Dai, Ying-Hong Shi, Jia Fan

“…Abstract Serine arginine-rich splicing factor 1 (SRSF1) is a key oncogenic splicing factor in various cancers, promoting abnormal gene expression through post-translational regulation. …”
Get full text

Combination Treatment of C16 Peptide and Angiopoietin-1 Alleviates Neuromyelitis Optica in an Experimental Model by Yuanyuan Zhang, Kewei Tian, Hong Jiang, Beibei Wang, Shu Han

“…We then tested whether the combination of C16, an αvβ3 integrin-binding peptide, and angiopoietin-1 (Ang1), a member of the endothelial growth factor family, could alleviate NMO in the model. …”
Get full text

A two-strain HIV-1 mathematical model to assess the effects of chemotherapy on disease parameters by Tinevimbo Shiri, Winston Garira, Senelani D. Musekwa

Subjects: “…hiv-1…”
Get full text

Upregulated FoxO1 promotes arrhythmogenesis in mice with heart failure and preserved ejection fraction by Thassio Mesquita, Rodrigo Miguel-dos-Santos, Weixin Liu, Mario Fournier, Russell G. Rogers, Jocelyn Alfaro, Asma Nawaz, Lizbeth Sanchez, Xaviar M. Jones, Liang Li, Eduardo Marbán, Eugenio Cingolani

“…Here, RNA sequencing identifies Forkhead Box1 (FoxO1) signaling as abnormal in male HFpEF hearts. …”
Get full text

MicroRNA-155 Participates in the Expression of LSD1 and Proinflammatory Cytokines in Rheumatoid Synovial Cells by Ziliang Yu, Hao Liu, Jianbo Fan, Feihu Chen, Wei Liu

“…Lysine-specific demethylase 1 (LSD1) has been found that it can ameliorate the severity of RA. …”
Get full text

Theoretical Analysis of the Mechanism of the 1,3-Dipolar Cycloaddition of Benzodiazepine with N-Aryl-C-ethoxycarbonylnitrilimine by Khadija Nabih, Mohamed Maatallah, Abdesselam Baouid, Abdellah Jarid

“…In this work, the mechanism and regio- and no-periselectivity of the 1,3-dipolar cycloaddition reaction of 2,4-dimethyl-3H-1,5-benzodiazepine with N-aryl-C-ethoxycarbonylnitrilimine have been studied using the DFT method at the B3LYP/6-31G(d) level of theory. …”
Get full text

Spin-One DKP Equation in the Presence of Coulomb and Harmonic Oscillator Interactions in (1 + 3)-Dimension by H. Hassanabadi, Z. Molaee, M. Ghominejad, S. Zarrinkamar

“…In this work, we study Duffin-Kemmer-Petiau equation in the presence of coulomb and harmonic oscillator potentials in (1+3)-dimension for spin-one particles and we obtain energy eigenvalues and corresponding eigenfunctions.…”
Get full text

Transcendence of $L(1,\chi _s)/\Pi $ in positive characteristic. A simple automata-style proof by Liu, Si-Han, Yao, Jia-Yan

“…Damamme proved in 1999 the transcendence of $L(1,\chi _s)/\Pi $ via a criterion of de Mathan. …”
Get full text