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    Vitamin D Receptor Gene Polymorphisms Influence T1D Susceptibility among Pakistanis by Maryam Mukhtar, Andleeb Batool, Abdul Wajid, Iram Qayyum

    Published 2017-01-01
    “…Polymorphism in VDR causes alterations in the functioning of vitamin D, leading to type 1 diabetes (T1D) predisposition. The aim of the present study was to determine VDR gene polymorphism in association with T1D in Pakistanis. …”
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    Gαq Regulates the Development of Rheumatoid Arthritis by Modulating Th1 Differentiation by Dashan Wang, Yuan Liu, Yan Li, Yan He, Jiyun Zhang, Guixiu Shi

    Published 2017-01-01
    “…In the present study, we aimed to find out whether Gαq controls RA via regulation of Th1 differentiation. We observed that the expression of Gαq was negatively correlated with the expression of signature Th1 cytokine (IFN-γ) in RA patients, which suggests a negative role of Gαq in differentiation of Th1 cells. …”
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  6. 2246

    Local delivery of TGF-β1-mRNA decreases fibrosis in osteochondral defects by Gianluca Fontana, Brett Nemke, Yan Lu, Connie Chamberlain, Jae-Sung Lee, Joshua A. Choe, Hongli Jiao, Michael Nelson, Margot Amitrano, Wan-Ju Li, Mark Markel, William L. Murphy

    Published 2025-03-01
    “…Tracking studies revealed that the clots were reliably maintained in the defects for at least 2 weeks. TGF-β1 mRNA delivery significantly increased TGF-β1 production in BMAC clots and increased early expression of articular chondrocyte markers within osteochondral defects. …”
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    Small Farm Food Safety, Fresh Produce: Part 1: Introduction to the PACE Principles by Brian Lapinski, Amy Simonne, Marilyn E. Swisher

    Published 2007-11-01
    “…FCS8842/FY966: Small Farm Food Safety, Fresh Produce—Part 1: Introduction to the PACE Principles (ufl.edu) Ask IFAS: Small Farm Food Safety series (ufl.edu) …”
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    Evidence for Transfer of Membranes from Mesenchymal Stem Cells to HL-1 Cardiac Cells by Robert A. Boomsma, David L. Geenen

    Published 2014-01-01
    “…MSC were layered onto confluent HL-1 cell cultures in a 1 : 4 ratio. MSC gained gap junction permeant calcein from HL-1 cells after 4 hours which was partially reduced by oleamide. …”
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    Extracellular vesicles contribute to the beneficial effects of exercise training in APP/PS1 mice by Oliver K. Fuller, Emma D. McLennan, Casey L. Egan, Nimna Perera, Lauren V. Terry, Jae Pyun, Mariana de Mendonca, Guilherme Defante Telles, Benoit Smeuninx, Emma L. Burrows, Ghizal Siddiqui, Darren J. Creek, John W. Scott, Michael A. Pearen, Pamali Fonseka, Joseph A. Nicolazzo, Suresh Mathivanan, Anthony J. Hannan, Grant A. Ramm, Martin Whitham, Mark A. Febbraio

    Published 2025-02-01
    “…Here, we first examined the effect of voluntary exercise training (VET) on energy metabolism and cognitive function in the APP/PS1 transgenic mouse (Tg) model of familial AD. Next, we profiled extracellular vesicles (EVs) and examined whether they may play a role in the protective effects of VET via intranasal administration of EVs, purified from the blood of sedentary (sEV) and/or acutely exercised (eEV) donor wild-type mice into APP/PS1Tg mice. …”
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    Lower Semicontinuity in L1 of a Class of Functionals Defined on BV with Carathéodory Integrands by T. Wunderli

    Published 2021-01-01
    “…We prove lower semicontinuity in L1Ω for a class of functionals G:BVΩ⟶ℝ of the form Gu=∫Ωgx,∇udx+∫ΩψxdDsu where g:Ω×ℝN⟶ℝ, Ω⊂ℝN is open and bounded, g·,p∈L1Ω for each p, satisfies the linear growth condition limp⟶∞gx,p/p=ψx∈CΩ∩L∞Ω, and is convex in p depending only on p for a.e. x. …”
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    Data Homogeneity Effect in Deep Learning-Based Prediction of Type 1 Diabetic Retinopathy by Jui-En Lo, Eugene Yu-Chuan Kang, Yun-Nung Chen, Yi-Ting Hsieh, Nan-Kai Wang, Ta-Ching Chen, Kuan-Jen Chen, Wei-Chi Wu, Yih-Shiou Hwang, Fu-Sung Lo, Chi-Chun Lai

    Published 2021-01-01
    “…This study is aimed at evaluating a deep transfer learning-based model for identifying diabetic retinopathy (DR) that was trained using a dataset with high variability and predominant type 2 diabetes (T2D) and comparing model performance with that in patients with type 1 diabetes (T1D). The Kaggle dataset, which is a publicly available dataset, was divided into training and testing Kaggle datasets. …”
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