Study on the Dynamic Biological Characteristics of Sca-1+ Hematopoietic Stem and Progenitor Cell Senescence by Shan Geng, Xin-Yi Mu, Xiong-Bin Chen, Ji-Ying Hou, Dao-Yong Jia, Chun-Yan Xu, Ya-Ping Wang

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Reduction of intestinal RIPK1 ameliorates HFD-induced metabolic disorders in female mice by Ye Yuan, Xiaomin Hu, Chunguang Guo, Yihua Xu, Shihan Li, Wei Wen, Xinli Hu, Fanxin Zeng, Weiyi Cui, Wenli Chen, Xueting Sun, Ning Hou, Jue Wang, Rui-Ping Xiao, Xiuqin Zhang

“…In this study, using receptor-interacting protein kinase 1 (Ripk1) intestine-specific heterozygous knockout mice (Ripk1IEC+/−) and high-fat diet (HFD)-feeding mouse model, we report that HFD-induced shift in the transcriptional profile of the ileum toward that of the jejunum, characterized by increased expression of jejunal feature genes in the ileum, are attenuated in Ripk1IEC+/− female mice, but not in males. …”
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Universal flops of length 1 and 2 from D2-branes at surface singularities by Marina Moleti, Roberto Valandro

“…We explore various cases, including when X is the universal flop of length ℓ = 1, 2. The effective theory, obtained after the introduction of Φ, provides valuable insights into the geometric features of X, such as the loci in parameter space where the fiber becomes singular and, more notably, the conditions under which this induces a singularity in the total space. …”
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Atherogenic ω-6 Lipids Modulate PPAR- EGR-1 Crosstalk in Vascular Cells by Jia Fei, Carla Cook, Miriah Gillespie, Bangning Yu, Khyra Fullen, Nalini Santanam

“…The objective of this study was to investigate if ω-6 lipids modulated the early growth response-1 (Egr-1)/PPAR crosstalk thereby altering vascular function. …”
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The Nrf-2/HO-1 Signaling Axis: A Ray of Hope in Cardiovascular Diseases by Xueyan Zhang, Yihan Yu, Hanyu Lei, Yufeng Cai, Jie Shen, Ping Zhu, Qingnan He, Mingyi Zhao

“…Nuclear factor erythropoietin-2-related factor 2/heme oxygenase 1 (Nrf2/HO-1) is a protein found in all cells of the human body. …”
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Pluripotency-State-Dependent Role of Dax1 in Embryonic Stem Cells Self-Renewal by Jianrong He, Yuda Cheng, Yan Ruan, Jiali Wang, Yanping Tian, Jiaqi Wang, Fengsheng Wang, Chen Zhang, Yixiao Xu, Lianlian Liu, Meng Yu, Jiangjun Wang, Binyu Zhao, Yue Zhang, Yi Yang, Gaoke Liu, Wei Wu, Ping He, Jiaxiang Xiong, He Huang, Junlei Zhang, Rui Jian

“…Dax1(also known as Nr0b1) is regarded as an important component of the transcription factor network in mouse embryonic stem cells (ESCs). …”
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Early growth response 1 transcription factor and its context-dependent functions in glioblastoma by Saleh Rasras, Esma’il Akade, Seyed Ehsan Mohammadianinejad, Maedeh Barahman, Mohammad Bahadoram

“…Current evidence suggest that early growth response 1 (EGR1) plays a dual role as both an oncogene and a tumour suppressor in glioblastoma. …”
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Evaluating Sampling Uncertainty in the Quantitative 1H Nuclear Magnetic Resonance Analysis of Lignin by Shrikant Shivaji Pawade, Lauri Toom, Koit Herodes, Ivo Leito

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Emergence of mcr-8.1-bearing MDR-hypervirulent Klebsiella pneumoniae ST307 by Jie Sheng, Rory Cave, Mary M. Ter-Stepanyan, Siyu Lu, Yingxiong Wang, Taihang Liu, Hermine V. Mkrtchyan

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Stroma-derived Dickkopf-1 contributes to the suppression of NK cell cytotoxicity in breast cancer by Seunghyun Lee, Biancamaria Ricci, Jennifer Tran, Emily Eul, Jiayu Ye, Qihao Ren, David Clever, Julia Wang, Pamela Wong, Michael S. Haas, Sheila A. Stewart, Cynthia X. Ma, Todd A. Fehniger, Roberta Faccio

“…Abstract Mechanisms related to tumor evasion from NK cell-mediated immune surveillance remain enigmatic. Dickkopf-1 (DKK1) is a Wnt/β-catenin inhibitor, whose levels correlate with breast cancer progression. …”
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Identification of new ClpC1-NTD binders for Mycobacterium tuberculosis drug development by Katharina Weinhäupl, Louis Meuret, Sandy Desrat, Fanny Roussy, Nelly Morellet, Sandra Beaupierre, Catherine Guillou, Carine van Heijenoort, Olga Abian, Sonia Vega, Ian Wolf, Tatos Akopian, Olga Krandor, Eric Rubin, Adrian Velazquez-Campoy, Diego Gauto, Hugo Fraga

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Medical and Psychological Risk Factors for Incident Hypertension in Type 1 Diabetic African-Americans by Monique S. Roy, Malvin N. Janal, Alec Roy

“…To determine risk factors for the development of hypertension among African-Americans living with type 1 diabetes. Methods. African-Americans with type 1 diabetes (n = 483) participated in a 6-year followup. …”
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Loss of LLGL1 Expression Correlates with Diffuse Gastric Cancer and Distant Peritoneal Metastases by Alexander Desuki, Frank Staib, Ines Gockel, Markus Moehler, Hauke Lang, Stefan Biesterfeld, Annett Maderer, Peter R. Galle, Martin R. Berger, Carl C. Schimanski

“…Background. Loss of LLGL1 has been associated with loss of cellular adhesion and dissemination of cells from colorectal cancer and malignant melanoma. …”
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Corrosion Inhibition Effect of Dicycloimine Hydrochloride (DCI) on Mild Steel in 1M HCl by R. Rajalakshmi, S. Subhashini

“…In this work, an attempt has been made to explore the possibility of using dicycloimine hydrochloride (DCI) as an inhibitor on mild steel in 1 M HCl. The inhibition efficiency of DCI has been evaluated by conventional weight loss method and electrochemical polarization studies. …”
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Oxidative Stress and Heme Oxygenase-1 Regulated Human Mesenchymal Stem Cells Differentiation by Luca Vanella, Christopher Sanford, Dong Hyun Kim, Nader G. Abraham, Nabil Ebraheim

“…This paper describes the effect of increased expression of HO-1 protein and increased levels of HO activity on differentiation of bone-marrow-derived human MSCs. …”
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Mechanisms of multidrug resistance caused by an Ipi1 mutation in the fungal pathogen Candida glabrata by Taiga Miyazaki, Shintaro Shimamura, Yohsuke Nagayoshi, Hironobu Nakayama, Akihiro Morita, Yutaka Tanaka, Yasuhiko Matsumoto, Tatsuo Inamine, Hiroshi Nishikawa, Nana Nakada, Makoto Sumiyoshi, Tatsuro Hirayama, Shigeru Kohno, Hiroshi Mukae

“…The Ipi1-Ssb/Ssz1 complex inhibits Pdr1-mediated gene expression and multidrug resistance in C. glabrata, in contrast to Saccharomyces cerevisiae where Ssz1 acts as a positive regulator of Pdr1. …”
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Dynamic Behaviors and Analytical Solutions of the Damped (2+1)-Dimensional Nonlinear Schrödinger Equation by Yongyi Gu, Feng Ye, Baixin Chen, Najva Aminakbari

“…In this paper, abundant analytical solutions of the damped (2 + 1)-dimensional nonlinear Schrödinger equation are achieved by taking advantage of the extended systematic method. …”
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The Process‐Oriented Understanding on the Reduced Double‐ITCZ Bias in the High‐Resolution CESM1 by Enze Dong, Fengfei Song, Lixin Wu, Lu Dong, Shengpeng Wang, Fukai Liu, Hong Wang

“…Here, by comparing a high‐ and low‐resolution state‐of‐the‐art model CESM1, it is found that the double‐ITCZ bias is largely reduced in the high‐resolution CESM1. …”
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Doctoral Education as an Institutional Resource for Training Research and Higher Education Personnel (Article 1) by B. I. Bednyi, A. A. Mironos, N. V. Rybakov

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Glutathione Peroxidase-1 Suppresses the Unfolded Protein Response upon Cigarette Smoke Exposure by Patrick Geraghty, Nathalie Baumlin, Matthias A. Salathe, Robert F. Foronjy, Jeanine M. D’Armiento

“…The antioxidant, glutathione peroxidase-1 (GPx-1), counters oxidative stress induced by cigarette smoke exposure. …”
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