Carbon Monoxide-Releasing Molecule-3 Suppresses Tumor Necrosis Factor-α- and Interleukin-1β-Induced Expression of Junctional Molecules on Human Gingival Fibroblasts via the Heme Oxygenase-1 Pathway by Jia Lv, Yongsheng Liu, Shuhan Jia, Yuna Zhang, Haoyang Tian, Jingyuan Li, Hui Song

“…CORM-3 reduced permeability and enhanced the expression of junctional complex molecules (ZO-1, VE-cadherin, and β-catenin) in TNF-α- and IL-1β-induced HGFs. …”
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Circulating immunological transcriptomic profile identifies DDX3Y and USP9Y on the Y chromosome as promising biomarkers for predicting response to programmed death 1/programmed death ligand 1 blockade by Liting You, Zhaodan Xin, Feifei Na, Min Chen, Yang Wen, Jin Li, Jiajia Song, Ling Bai, Jianzhao Zhai, Xiaohan Zhou, Binwu Ying, Juan Zhou, Peifang Wei

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Discovery of a Novel Shared Variant Among RTEL1 Gene and RTEL1-TNFRSF6B lncRNA at Chromosome 20q13.33 in Familial Progressive Myoclonus Epilepsy by Sima Chaudhari, Lavanya Prakash Acharya, Dushyanth Babu Jasti, Akshay Pramod Ware, Sankar Prasad Gorthi, Kapaettu Satyamoorthy

“…Conclusions: Our study is the first to report variants in KCNH8, RTEL1, and RTEL1-TNFRSF6B among PME cases. These genes when characterized fully may shed light on pathogenicity and have the potential to be used in the diagnosis of PME.…”
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Crystal structure of 6-(pyridin-3-yl)-1,3,5-triazine-2,4-diamine-sebacic acid (2/1), C13H17N6O2 by Wang Zhi-Yong, Qian Peng-Xin, Yang Xian-Jiong, Zhang Qi-Long, Xu Hong, Huang Ya-Li

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Teste de Inteligência não verbal R-1: o tamanho do efeito para as normas de 2018 // R-1 non-verbal intelligence test: the effect size for the 2018 standards by Augusto Dias

“…O estudo apresenta os tamanhos do efeito, seus intervalos de confiança, classificações e visualizações para a atualização normativa de 2018 do Teste não verbal de Inteligência R-1, visto que as diferenças estatisticamente calculadas com base no valor p oferecerem evidências tênues contra a hipótese nula e, por isso, não servem como uma prova da significância clínica. …”
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Discussion: Comments on the Article Titled as “Bitlis Air Pollution Emission Inventory and Estimation of Health Effects by Multiple Linear Regression” (Journal of Natural Hazards and Environment, January 2019, 5(1): 1-10) by Edip Avşar

“…According to the article published in Journal of Natural Hazards and Environment, titled as “Bitlis Air Pollution Emission Inventory and Estimation of Health Effects by Multiple Linear Regression” (January 2019, 5(1): 1-10); mass discharges for the parameters of SOx, NOx, PM10 and CO were estimated by means of 2015 burned coal data in Bitlis. …”
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Design, synthesis, and anti-inflammatory activity of 2H-1,4-benzoxazin-3(4H)-one derivatives modified with 1,2,3-triazole in LPS-induced BV-2 cells by Xixi Hou, Xixi Hou, Longfei Mao, Huibin Zhang, Lan Wang, Baoyu He, Jingjing Guo, Jianji Wang

Subjects: “…1,2,3-triazoles…”
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Discovery of New Ligand with Quinoline Scaffold as Potent Allosteric Inhibitor of HIV-1 and Its Copper Complexes as a Powerful Catalyst for the Synthesis of Chiral Benzimidazole Derivatives, and in Silico Anti-HIV-1 Studies by Sabikeh G. Azimi, Ghodsieh Bagherzade, Mohammad Reza Saberi, Zeinab Amiri Tehranizadeh

“…The potency of these compounds as anti-HIV-1 agents was investigated using molecular docking into integrase (IN) enzyme with code 1QS4 and the GROMACS software for molecular dynamics simulation. …”
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Remarkable Conversion of 2-Thioxo-2,3-dihydroquinazolin-4(1H)-ones into the Corresponding Quinazoline-2,4(1H,3H)-diones: Spectroscopic Analysis and X-Ray Crystallography by Adel S. El-Azab, Nasr Y. Khalil, Alaa A.-M. Abdel-Aziz

“…The crystal structure of 6-methyl-3-phenylquinazoline-2,4(1H,3H)-dione (11) [C15H12N2O2: MF = 252.27, triclinic, P-1, a = 7.8495 (13) Å, b = 12.456 (2) Å, c = 13.350 (2) Å, α = 103.322 (3)°, β = 90.002 (3)°, γ = 102.671 (4)°, V = 1237.5 (3) Å3, Z = 4, R = 0.0592, wR = 0.1699, S = 1.039] was determined. …”
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Efficacy and safety of PD-1 inhibitors as second-line treatment for advanced squamous esophageal cancer: a systematic review and network meta-analysis with a focus on PD-L1 expression levels by Fei Yang, Min Dan, Jindan Shi, Ling Fan, Haoluo Zhang, Tiantian Jian, Kelu Lei, Yue Wang, Juan Xin, Zhigang Yu, Wei Chen

“…BackgroundPD-1 inhibitors have shown promising efficacy in enhancing OS and AEs as second-line therapies for patients with advanced esophageal squamous cell carcinoma (ESCC). …”
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Synthesis and Biological Activity of Some 3,4-Dihydro-4-(4-substituted aryl)-6-(naptho[2,1-b]furan-2-yl pyrimidine-2(1H)-one Derivatives by Sanjeevan S. Gaikwad, Venkat S. Suryawanshi, Kishan S. Lohar, Dhanaji V. Jadhav, Narayan D. Shinde

“…The synthesized oxopyrimidine derivatives were characterized by means of their IR, 1H NMR, mass spectral data and elemental analysis. …”
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Construction of Direct Z-Scheme Photocatalyst by Mg1.2Ti1.8O5 and g-C3N4 Nanosheets toward Photocatalytic H2 Production and Disinfection by Sijia Gu, Dan Zhang, Shirong Luo, Heng Yang

“…Herein, Z-scheme heterojunction composites were successfully fabricated by loading g-C3N4 nanosheets (CN) on the surface of Mg1.2Ti1.8O5 nanoflakes (MT) through a simple sol-gel method followed by the calcination method. …”
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Inhibiting ATP6V0D2 Aggravates Liver Ischemia-Reperfusion Injury by Promoting NLRP3 Activation via Impairing Autophagic Flux Independent of Notch1/Hes1 by Ziyi Wang, Hao Wang, Xuejiao Chen, Sheng Han, Yulin Zhu, Hanhua Wang, Feng Cheng, Liyong Pu

“…In general, we illustrated that the expression of ATP6V0D2 in liver macrophages was upregulated after liver IR, and by gradually promoting the formation of autophagolysosomes to increase autophagy flux to limit the activation of liver inflammation, this regulation is independent of the Notch1-Hes1 signal axis.…”
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Genome drafting of nosocomial infection CRE Klebsiella pneumoniae confirming resistance to colistin and eravacycline, carrying blaNDM-1, mcr-1, and blaKPC-2, in neonatology from November to December 2023 by Xinlong Zhou, Kailash Wagh, Guizhen Lv, Devender Sharma, Wei Lei

“…All isolates were resistant to colistin and carried resistance genes, including mcr-1 and blaNDM-1,blaKPC2 confirming carbapenem resistance. …”
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A systematic review of Streptococcus Mutans and Veillonellae species interactions in dental caries progression: Positive or Negative impact? [version 2; peer review: 1 approved, 2 approved with reservations, 1 not approved] by Faizul Hasan, Prawati Nuraini, Ariadna Adisattya Djais, Ervina Restiwulan Winoto, Tantiana Tantiana, Rini Devijanti Ridwan, Juni Handajani, Rajesh Ramasamy, Silvia Anitasari, Hendrik Setia Budi

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Crystal structure of 1-cyclopropyl-7-ethoxy-6,8-difluoro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid, C15H13F2NO4 by Zhang Chun-Yan, Nie Xu-Liang, Huang Guo-Ping, Xiong Yuan-Zhen, Huang Jian-Ping

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Research progress of hypoxia-inducible factor-1α and zinc in the mechanism of diabetic kidney disease by Wei Qin, Ping Nie, Xuejun Hui, Fei Chen, Xingbao Hu, Wenjiao Shi, Manyu Luo, Bing Li

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Association of pituitary neuroendocrine tumors and neurofibromatosis type 1: assessing causation versus coincidence. Case report by Mercedes Aguilar-Soto, Julia M. Zuarth-Vázquez, Laura Leyva-Figueroa, Karla Zarco-Ávila, Armando Gamboa-Domínguez, Aldo Eguiluz-Melendez, Laura C. Hernández-Ramírez

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Analyse de l’effet L1 dans l’émergence de l’auxiliation en français L2 by Cyrille Granget

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Editörden by Tolga Çakmak

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