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2841
Intratumoral <i>Fusobacterium nucleatum</i> in Pancreatic Cancer: Current and Future Perspectives
Published 2024-12-01“…<i>Fn</i> engages in pancreatic tumorigenesis and metastasis through multifaceted mechanisms, including immune response modulation, virulence factors, control of cell proliferation, intestinal metabolite interactions, DNA damage, and epithelial–mesenchymal transition. …”
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2842
G Protein-Coupled Receptor 17 Inhibits Glucagon-like Peptide-1 Secretion via a Gi/o-Dependent Mechanism in Enteroendocrine Cells
Published 2024-12-01“…We previously showed that G protein-coupled receptor 17 (GPR17) is expressed in intestinal enteroendocrine cells (EECs) and modulates nutrient-induced GLP-1 secretion. …”
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2843
A microfluidics platform for simultaneous evaluation of sensitivity and side effects of anti-cancer drugs using a three-dimensional culture method
Published 2025-01-01“…In the present study, we designed and fabricated an organ-on-a-chip system for mounting organoids from mammary tumor-affected cats (FMT organoids) and normal intestinal organoids from mice (MI organoids) and perfused them with anti-cancer drugs. …”
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2844
Role of Bone Marrow-Derived Stem Cells in Polyps Development in Mice with ApcMin/+ Mutation
Published 2015-01-01“…We explored the hypothesis that an altered microenvironment (intestinal adenomatous polyp) could modify the differentiation program of bone marrow-derived stem cells (BMSCs), involving them in colon carcinogenesis. …”
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2845
Akkermansia muciniphila Enhances the Antitumor Effect of Cisplatin in Lewis Lung Cancer Mice
Published 2020-01-01“…Recently, intestinal flora plays a vital role in the occurrence and development of tumors and there is link between cancer immunotherapy and Akkermansia muciniphila (Akk). …”
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2846
Profiling the response of individual gut microbes to free fatty acids (FFAs) found in human milk
Published 2025-02-01“…Preterm infants have an immature intestinal environment featuring microbial dysbiosis. …”
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2847
Leverage of lysozyme dietary supplementation on gut health, hematological, antioxidant, and immune parameters in different plumage-colors Japanese quails
Published 2025-01-01“…For gut status, both varieties exhibited increases in intestinal villi length and goblet cell count with significant reductions in the total lactobacillus, total coliform, and total bacterial counts. …”
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2848
Multi-trace elements-enriched functional drink accelerates gastric ulcer repair via the HGF/c-Met/STAT3 pathway
Published 2025-02-01“…It also effectively regulate the abundance and diversity of intestinal flora. Finally, FD reduced the severity of gastric mucosal injury caused by invasive factors, improved the morphological structure of gastric mucosal cells, enhanced the ability of oxidative stress, and inhibited excessive inflammatory response. …”
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2849
Infections with Giardia duodenalis and Entamoeba histolytica/Entamoeba dispar as Hidden and Prevalent Conditions in Periurban Communities in the State of Rio de Janeiro, Brazil
Published 2020-01-01“…This study aims to assess the prevalence, distribution, and etiological profile of intestinal parasitism in children living in periurban areas in Cachoeiras de Macacu, Rio de Janeiro, Brazil. …”
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2850
Duplex qPCR for detecting and differentiating porcine epidemic diarrhea virus GI and GII subtypes
Published 2025-01-01“…IntroductionPorcine epidemic diarrhea virus (PEDV) is a pathogen that causes a highly contagious intestinal disease in pigs, which causes significant economic losses to the pig industry worldwide. …”
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2851
Fusobacterium nucleatum promotes colorectal cancer liver metastasis via miR-5692a/IL-8 axis by inducing epithelial-mesenchymal transition
Published 2025-01-01“…Abstract Background The association between the intestinal microbiota and colorectal cancer (CRC) has been extensively studied, with Fusobacterium nucleatum (F. nucleatum, FN) being found in high abundance in colorectal cancer tissues. …”
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2852
Deficiency of Dietary Fiber in Slc5a8-Null Mice Promotes Bacterial Dysbiosis and Alters Colonic Epithelial Transcriptome towards Proinflammatory Milieu
Published 2019-01-01“…Inflammatory bowel disease (IBD) is characterized by chronic inflammation in the intestinal tract due to disruption of the symbiotic relationship between the host immune system and microbiota. …”
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2853
Retrospective Investigation of Cytomegalovirus and Epstein–Barr Virus Positivity in Inflammatory Bowel Disease Patient Biopsies
Published 2024-01-01“…The aim of this study was to investigate the distribution of cytomegalovirus (CMV) and Epstein-Barr virus (EBV) in the intestinal tissue of patients with IBD. Methods: The study included tissue samples taken from 50 IBD (32 male, 18 female, between the ages of 18-76) patients. …”
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2854
Achieving healthy aging through gut microbiota-directed dietary intervention: Focusing on microbial biomarkers and host mechanisms
Published 2025-02-01“…Aim of Review: This review aims to summarize the characteristics of the gut microbiota associated with aging, explore potential biomarkers of aging and address microbiota-associated mechanisms of host aging focusing on intestinal barrier and immune status. By summarizing the existing effective dietary strategies in aging interventions, the probability of developing a diet targeting the gut microbiota in future is provided. …”
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2855
Glycerol Monolaurate Complex Improved Antioxidant, Anti-Inflammation, and Gut Microbiota Composition of Offspring in a Sow–Piglet Model
Published 2025-01-01“…In conclusion, GML enhanced reproductive and growth performance by improving antioxidant and anti-inflammatory status and maintaining intestinal flora balance, making it a promising alternative to ATLL in future applications.…”
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2856
Mechanically powered negative pressure dressing reduces surgical site infection after stoma reversal
Published 2025-01-01“…Post-op LOS in the study group versus was 4.1 days. Conclusion: Intestinal stoma reversal wounds closed primarily and dressed with the MP-NPD dressings had very low stoma site SSI rates. …”
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2857
Analysis of nanomedicine applications for inflammatory bowel disease: structural and temporal dynamics, research hotspots, and emerging trends
Published 2025-01-01“…Keyword analysis revealed that current research hotspots include drug delivery, immune cell regulation, antioxidant damage, intestinal microbiota homeostasis, and nanovesicles.ConclusionThis study offers a comprehensive overview of global research landscape, emphasizing the rapid growth and increasing complexity of this field. …”
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2858
Small Bowel Bacterial Overgrowth Syndrome in Patients with Bronchial Asthma
Published 2018-09-01“…The correction of composition disorders of the intestinal microflora is accompanied by a statistically significant decrease in the immune response (p < 0.01) and improvement in the function of external respiration (p < 0.001).Conclusion. …”
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2859
Enhancement of Growth, Antioxidant Activity, and Immunity in Nile Tilapia (<i>Oreochromis niloticus</i>) Through Recombinant <i>Bacillus subtilis</i> Expressing L-Gulonolactone Oxi...
Published 2025-01-01“…HPLC and qRT-PCR analyses revealed elevated serum vitamin C and intestinal <i>GULO</i> mRNA levels in the BS+GULO group. …”
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2860
Prediction of the Clinical Outcomes of Sigmoid Volvulus by Abdominal X-Ray: AXIS Classification System
Published 2018-01-01“…We examined the association between AXIS classification and severe sigmoid volvulus, intestinal necrosis, need for surgery, 30-day mortality, and length of stay using the Cochran–Armitage trend test. …”
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