VANGL2 alleviates inflammatory bowel disease by recruiting the ubiquitin ligase MARCH8 to limit NLRP3 inflammasome activation through OPTN-mediated selective autophagy. by Huaji Jiang, Yingchao Xie, Zhiqiang Hu, Jiansen Lu, Jiahuan Zhang, Hongyu Li, Ke Zeng, Wenqiang Peng, Cheng Yang, Junsheng Huang, Zelong Han, Xiaochun Bai, Xiao Yu

“…Inflammatory bowel disease (IBD) is a chronic and potentially life-threatening inflammatory disease of gastroenteric tissue characterized by episodes of intestinal inflammation, but the underlying mechanisms remain elusive. …”
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Surgical strategy in a patient with an aggressive tumor of the gastrointestinal tract in the fourth portion of the duodenum by Tomás Ariel Lombardo Vaillant

“…The surgical procedure was resection of the duodenum fourth portion and the first jejunal loops, with restoration of intestinal function through duodenum (second portion) lateral jejunostomy. …”
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Pregnancy and Healthy Childbirth in a 37 Year-Old Patient with Diverticular Disease by P. S. Andreev, S. E. Katorkin, O. E. Davydova

“…Rifaximin-α, which has a poor intestinal absorption, did not affect the foetal development. …”
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An Overview of the Role of Innate Lymphoid Cells in Gut Infections and Inflammation by Silvia Sedda, Irene Marafini, Michele M. Figliuzzi, Francesco Pallone, Giovanni Monteleone

“…In this review, we will summarize the present knowledge on the distribution of ILCs in the intestinal mucosa, with particular focus on their role in the control of both infections and effector cytokine response in immune-mediated pathologies.…”
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The Effect of Sleep Disruption on Cardiometabolic Health by SeokHyun Hong, Da-Been Lee, Dae-Wui Yoon, Seung-Lim Yoo, Jinkwan Kim

“…The latest evidence points to the role of sleep-induced changes in the composition and function of gut microbiota, which may contribute to metabolic dysfunction through modifications in the intestinal barrier and inflammatory responses. The NLRP3 inflammasome and NF-κB signaling pathways have been identified as crucial mediators linking sleep disruption to metabolic inflammation. …”
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Pneumatosis Intestinalis as the Initial Presentation of Systemic Sclerosis: A Case Report and Review of the Literature by Farshid Ejtehadi, Nikolaos A. Chatzizacharias, Hugh Kennedy

“…Pneumatosis intestinalis (PI) is an uncommon pathology characterised by the presence of gas within the intestinal wall. It has been associated with various conditions, including connective tissue diseases. …”
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Immunological disturbance effect of exogenous histamine towards key immune cells by Yanan Liu, Huan Li, Chong Wang, Shanjun Chen, Renjie Lian, Weiqiang Wang, Linglin Fu, Yanbo Wang

“…In this work, we explored the effects of exogenous histamine on the function of key immune cells such as intestinal epithelial cells, dendritic cells, and T cells. …”
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Sodium butyrate attenuate hyperglycemia-induced inflammatory response and renal injury in diabetic mice by Yan Man, Zhang Yan-Yan, Xi Yue, Ding Long-Kun, Sun Chang, Qu Li-Juan, Qian Xin, Xu Jing-Wen, Sun Wen, Wu Liang

“…This study aimed to evaluate the effect and mechanism of butyrate (NaB), a metabolite of intestinal flora, on inhibiting the inflammatory response of human monocyte-macrophages (THP-1 cells) induced by high glucose and the damage of pancreatic and renal tissue in diabetic mice. …”
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Modulatory effects of Lactiplantibacillus plantarum on chronic metabolic diseases by Lei Tian, Ruixiang Zhao, Xinyi Xu, Zhiwei Zhou, Xiaofang Xu, Dongmei Luo, Zhiqiang Zhou, Yu Liu, Ariel Kushmaro, Robert S. Marks, András Dinnyés, Qun Sun

“…Ingesting L. plantarum demonstrated its ability to reduce inflammatory and oxidative stress levels by regulating the production of cytokines and short-chain fatty acids (SCFAs), the activity of antioxidant enzymes, and the balance of intestinal microbial communities to alleviate the symptoms of chronic metabolic diseases. …”
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Differential Diagnosis of Entamoeba spp. in Clinical Stool Samples Using SYBR Green Real-Time Polymerase Chain Reaction by Thiago dos Santos Gomes, Mariana Coimbra Garcia, Flavia de Souza Cunha, Heloisa Werneck de Macedo, José Mauro Peralta, Regina Helena Saramago Peralta

“…Negative controls and other intestinal parasites presented no amplification. Among the 48 samples tested, E. dispar DNA was detected in 37; none exhibited E. histolytica DNA and 11 were negative in the multiplex protocol. …”
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An Emerging Role of Glucagon-Like Peptide-1 in Preventing Advanced-Glycation-End-Product-Mediated Damages in Diabetes by Alessandra Puddu, François Mach, Alessio Nencioni, Giorgio Luciano Viviani, Fabrizio Montecucco

“…Glucagon-like peptide-1 (GLP-1) is a gut hormone produced in the intestinal epithelial endocrine L cells by differential processing of the proglucagon gene. …”
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Research advance of Bacillus velezensis: bioinformatics, characteristics, and applications by Ting Su, Biao Shen, Xingjuan Hu, Yue Teng, Peifang Weng, Zufang Wu, Lianliang Liu

“…It possesses high bile-salt tolerance characteristics and has a high success rate of colonization in the intestinal mucosa. Besides, the strain can also regulate gut microbiota constitute by increasing the number of beneficial microorganisms and decreasing the number of pathogens. …”
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Comparative multiomics analyses reveal the breed effect on the colonic host–microbe interactions in pig by Liang Huang, Shiqi Luo, Shuqi Liu, Mingliang Jin, Yizhen Wang, Xin Zong

“…Notably, Pacebacteria, Streptophyta, and Aerophobetes were found to participate in the PI3K‐Akt mediated immune response in both pig breeds; however, they only accelerated the metabolism in the intestines of JXB pigs. Moreover, the host could regulate microbe metabolism and immune response by Ig‐like domain‐containing protein and ITIH2, PAEP, and TDRD9, respectively. …”
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Impact of Duodopa on Quality of Life in Advanced Parkinson's Disease: A UK Case Series by T. Foltynie, C. Magee, C. James, G. J. M. Webster, A. J. Lees, P. Limousin

“…Treatment options in advanced Parkinson’s disease (PD) include subcutaneous apomorphine, pallidal or subthalamic nucleus Deep Brain Stimulation (DBS), or levodopa/carbidopa intestinal gel (LCIG/Duodopa). In this study, we describe the outcome of 12 PD patients with PD related complications started on LCIG, with respect to their quality of life measured by a disease specific validated scale—the PDQ39, together with diaries recording time spent “On,” “Off,” “Dyskinetic,” or “Asleep.” …”
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Early-life gut mycobiome core species modulate metabolic health in mice by Mackenzie W. Gutierrez, Erik van Tilburg Bernardes, Ellen Ren, Kristen N. Kalbfleisch, Madeline Day, Ewandson Luiz Lameu, Thaís Glatthardt, Emily M. Mercer, Sunita Sharma, Hong Zhang, Ali Al-Azawy, Faye Chleilat, Simon A. Hirota, Raylene A. Reimer, Marie-Claire Arrieta

“…In contrast, C. albicans resulted in leanness and resistance to diet-induced obesity. Intestinal nutrient transporter expression was unaffected by the presence of fungi in jejunal enteroids, yet the immune landscape in white adipose tissue was distinctly impacted by each fungal species, suggesting that these phenotypes may be a result of fungal immune regulation. …”
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Paediatric Inflammatory Bowel Disease: A Mechanistic Approach to Investigate Exclusive Enteral Nutrition Treatment by Lily Nahidi, Andrew S. Day, Daniel A. Lemberg, Steven T. Leach

“…This review will discuss recent research into EEN both describing clinical features of EEN therapy and discussing the most up-to-date understanding of the mechanisms through which EEN may be reducing intestinal inflammation and inducing disease remission.…”
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Authentication of Processed Epimedii folium by EA-IRMS by Fengyan He, Mengyi Li, Yi He, Zhe Dong, Jin Cao, Zhong Dai, Shuangcheng Ma

“…It has been reported that processing EF with mutton fat could improve the bioavailability and intestinal absorption of epimedium flavonoids and thus enhances the pharmacological effects. …”
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An Appendix Origin Burkitt’s Lymphoma Spreading into Genital Tract by Mustafa Ulubay, Fahri Burçin Fıratlıgil, Uğur Keskin, Ulaş Fidan, Mehmet Gamsızkan, Müfit Cemal Yenen, Ali Ergün

“…The hemicolectomy process was needed to reduce the tumour burden and because of the risk of intestinal obstruction risk that could arise from the tumour mass in the ileocecal valve. …”
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Deoxycholic Acid Could Induce Apoptosis and Trigger Gastric Carcinogenesis on Gastric Epithelial Cells by Quantitative Proteomic Analysis by Yanyan Shi, Ying Wei, Ting Zhang, Jing Zhang, Ye Wang, Shigang Ding

“…Bile reflux has been generally considered to be associated with intestinal metaplasia and gastric cancer. However, the pathogenic mechanisms of the effects of bile acids on gastric mucosa are still unknown. …”
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Supplementation with yak (Bos grunniens) bone collagen hydrolysate altered the structure of gut microbiota and elevated short-chain fatty acid production in mice by Zitao Guo, Dalong Yi, Bo Hu, Lingyu Zhu, Ji Zhang, Yuliang Yang, Chunyu Liu, Yi Shi, Zhenghua Gu, Yu Xin, Huaigao Liu, Liang Zhang

“…These results indicated that YBCH might be applied in the development of functional food for intestinal microecological regulation.…”
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