Relieving Effect of <i>Artemisia ordosica Krasch</i> Extract on DSS-Induced Colitis by Regulating Immunity, Antioxidant Function, Gut Microbiota, and Bile Acid Metabolism in Mice by Min Jiang, Xuekai Zhang, Xiao Jin, Binlin Shi, Yuanqing Xu, Zheqi Wang

“…We evaluated the impact of AOE on intestinal microbiota by measuring the 16s sequencing of cecal contents and bile acid metabolism. …”
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Effects of Dietary Yeast, Saccharomyces cerevisiae, and Costmary, Tanacetum balsamita, Essential Oil on Growth Performance, Digestive Enzymes, Biochemical Parameters, and Disease R... by Hossein Adineh, Morteza Yousefi, Basim S. A. Al Sulivany, Ehsan Ahmadifar, Mohammad Farhangi, Seyyed Morteza Hoseini

“…Sc group showed significant elevations in the intestinal amylase, lipase, and protease activities, but Tb group showed only elevation in lipase activity. …”
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Mother-fetus immunogenetic dialogue as a factor of progeny immune system development by L. A. Gerlinskaya, A. V. Varlachev, G. I. Krotov, G. V. Kontsevaya, M. P. Moshkin

“…It has been shown that immunoglobulins from the milk of many animal species are transferred through the neonatal intestinal epithelium to the blood. Since breast milk contains large amounts of various immunoactive components, including proteins, cytokines, hormones, immunoglobulins, exosomes containing micro-RNA, and viable immune cells, the immunomodulating effects of breast milk persist even after elimination of maternal immunoglobulins from the blood of the offspring, up to maturation. …”
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Electroacupuncture and Tongbian decoction ameliorate CUMS-induced depression and constipation in mice via TPH2/5-HT pathway of the gut-brain axis by Yi Chen, Peihua Shen, Qi Li, Shun Seng Ong, Yunzhi Qian, Hai Lu, Ming Li, Tianshu Xu

“…Furthermore, EA + TB reduced intestinal inflammation, restored neuronal morphology, increased the expression of tryptophan hydroxylase 2 (TPH2) in both the prefrontal cortex (PFC) and colon, elevated the serum levels of 5-hydroxytryptophan (5-HTP)—a molecule that acts as a gut-brain connector—and promoted the synthesis and production of serotonin (5-HT) in both the gastrointestinal tract and the brain. …”
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Does therapy with immunosuppressive drugs improve gastrointestinal symptoms in patients with systemic sclerosis? by Oliver Distler, Cosimo Bruni, Suzana Jordan, Carina Mihai, Muriel Elhai, Rucsandra Dobrota, Alexandru Garaiman, Mike Oliver Becker, Lea Stamm, Sherif Ismail, Norina Zampatti, Aurora Maria Tatu

“…We aimed to identify an association between immunosuppressive therapy and the the severity of GI symptoms, measured by the University of California at Los Angeles/Scleroderma Clinical Trial Consortium Gastro-Intestinal Tract instrument 2.0 (GIT).Methods We selected patients with SSc who had at least two visits (further referred to as ‘baseline’ and ‘follow-up’) with completed GITs, within an interval of 12±3 months. …”
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Cell Wall Protein 2 as a Vaccine Candidate Protects Mice Against <i>Clostridioides difficile</i> Infection by Shaohui Wang, Joshua Heuler, Jessica Bullock, Junling Qin, Soumyadeep Chakraborty, Agbendeh Lubem Nathaniel, Shifeng Wang, Xingmin Sun

“…Background/Objectives: <i>Clostridioides difficile</i> is a Gram-positive, spore-forming enteric pathogen that causes intestinal disorders, including inflammation and diarrhea, primarily through toxin production. …”
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Tgfbr1 regulates lateral plate mesoderm and endoderm reorganization during the trunk to tail transition by Anastasiia Lozovska, Ana Casaca, Ana Novoa, Ying-Yi Kuo, Arnon D Jurberg, Gabriel G Martins, Anna-Katerina Hadjantonakis, Moises Mallo

“…During the trunk to tail transition the mammalian embryo builds the outlets for the intestinal and urogenital tracts, lays down the primordia for the hindlimb and external genitalia, and switches from the epiblast/primitive streak (PS) to the tail bud as the driver of axial extension. …”
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Avolition Characterizes the Chronic Fatigue Experienced in Quiescent Inflammatory Bowel Disease by Tristan Gabriel-Segard, Margherita Boltri, Mathilde Barrau, Catherine Massoubre, Stéphane Paul, Xavier Roblin

“…<b>Conclusions:</b> To tackle the question of fatigue in IBD, research should consider investigating the biological mechanisms implicating intestinal physiopathology of IBD in the impairment of brain structure involved in motivation. …”
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Volatile Organic Compounds as Biomarkers of Gastrointestinal Diseases and Nutritional Status by Mariangela Rondanelli, Federica Perdoni, Vittoria Infantino, Milena Anna Faliva, Gabriella Peroni, Giancarlo Iannello, Mara Nichetti, Tariq A. Alalwan, Simone Perna, Clementina Cocuzza

“…VOC analysis has allowed us to highlight differences in lifestyles, intestinal microbiota, and metabolism. New innovative methods have been described that allow the detection and quantification of a broad spectrum of metabolites present in exhaled breath even at very low levels, some of which have been shown to be indicators of pathological conditions. …”
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Autophagy inhibitor 3-methyladenine mitigates the severity of colitis in aged mice by inhibiting autophagy by Ailing Liu, Hongying Wang, Hong Lv, Hong Yang, Yue Li, Jiaming Qian

“…Treatment with 3-methyladenine suppressed autophagy in intestinal epithelial cells (IECs) and alleviated colitis severity. …”
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Protocol for a systematic review on routine use of antibiotics for infants less than 6 months of age with growth failure/faltering by Jai K Das, Zulfiqar Ahmed Bhutta, Abigail Smith, Aamer Imdad, Emily Tanner-Smith, Melissa François, Fanny F Chen, Olivia J Tsistinas

“…We will consider the following outcomes: mortality, clinical deterioration, antimicrobial resistance, recovery from comorbidity, adverse events, markers of intestinal inflammation, markers of systemic inflammation, hospital-acquired infections, non-response. …”
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Monocytes serve as Shiga toxin carriers during the development of hemolytic uremic syndrome by Xinlei Sun, Shuang Qu, Fenglian Zhou, Fujie Shi, Yunfei Wu, Lin Gu, Minghui Liu, Zhen Bian, Lei Shi, Zhihong Liu, Yuan Liu, Ke Zen

“…To exert its cytotoxic effect on renal cells, Stx must be delivered from the infected intestines to the kidney. However, the mechanism underlying Stx delivery remains unclear. …”
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The role of Akkermansia muciniphila in maintaining health: a bibliometric study by Fangfang Gao, Canyu Cheng, Canyu Cheng, Runwei Li, Zongcun Chen, Zongcun Chen, Ke Tang, Guankui Du, Guankui Du, Guankui Du

“…Thirty-nine high-frequency keywords were grouped into five clusters, illustrating Akkermansia muciniphila’s associations with metabolic diseases, chronic kidney disease, the gut-brain axis, intestinal inflammation, and Bacteroidetes-Firmicutes shifts.ConclusionGiven Akkermansia muciniphila’s anti-inflammatory and gut-barrier-strengthening properties, it holds promise as a therapeutic for obesity, metabolic disorders, and inflammatory conditions. …”
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Liver Expression of Sulphotransferase 2A1 Enzyme Is Impaired in Patients with Primary Sclerosing Cholangitis: Lack of the Response to Enhanced Expression of PXR by Ewa Wunsch, Marta Klak, Urszula Wasik, Malgorzata Milkiewicz, Malgorzata Blatkiewicz, Elzbieta Urasinska, Olivier Barbier, Dariusz Bielicki, Dimitrios P. Bogdanos, Elwyn Elias, Piotr Milkiewicz

“…PXR and SULT2A1 mRNA was analyzed in intestinal tissues from 22 PSC patients. Genomic DNA was isolated from blood of PSC patients (n=120) and an equal number of healthy volunteers. …”
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Gut Microbiota, Microinflammation, Metabolic Profile, and Zonulin Concentration in Obese and Normal Weight Subjects by Agnieszka Żak-Gołąb, Piotr Kocełak, Małgorzata Aptekorz, Maria Zientara, Łukasz Juszczyk, Gayane Martirosian, Jerzy Chudek, Magdalena Olszanecka-Glinianowicz

“…The association between gut microbiota and circulating zonulin level, a marker of intestinal permeability, has not been studied yet. The aim of the study is the assessment of plasma zonulin, haptoglobin and proinflammatory cytokines (TNF-α and IL-6) levels in relation to composition of gut microbiota in obese and normal weight subjects. …”
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Urinary I-FABP, L-FABP, TFF-3, and SAA Can Diagnose and Predict the Disease Course in Necrotizing Enterocolitis at the Early Stage of Disease by Stepan Coufal, Alena Kokesova, Helena Tlaskalova-Hogenova, Barbora Frybova, Jiri Snajdauf, Michal Rygl, Miloslav Kverka

“…Therefore, we analyzed diagnostic and prognostic potential of the markers of early NEC pathogenesis, such as excessive inflammatory response (serum amyloid A (SAA)) and gut epithelium damage (intestinal and liver fatty acid-binding protein (I-FABP and L-FABP, respectively) and trefoil factor-3 (TFF-3)). …”
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Microbial dynamics of acute pancreatitis: integrating culture, sequencing, and bile impact on bacterial populations and gaseous metabolites by Agnieszka Chmielarczyk, Edyta Golińska, Anna Tomusiak-Plebanek, Natalia Żeber-Lubecka, Natalia Żeber-Lubecka, Maria Kulecka, Maria Kulecka, Antoni Szczepanik, Katarzyna Jedlińska, Krzysztof Mech, Konrad Szaciłowski, Agata Kuziak, Agata Pietrzyk, Magdalena Strus

“…BackgroundOur study examined the composition of the intestinal microflora in a hospitalized patient with AP symptoms treated several months earlier for diverticulitis. …”
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Joint Group and Multi Institutional Position Opinion: Cirrhotic Cardiomyopathy—From Fundamentals to Applied Tactics by Ivan Rankovic, Ivana Babic, Jelena Martinov Nestorov, Jelena Bogdanovic, Maja Stojanovic, Jovanka Trifunovic, Nikola Panic, Mihailo Bezmarevic, Jelena Jevtovic, Dusan Micic, Vladimir Dedovic, Nemanja Djuricic, Filip Pilipovic, Elena Curakova Ristovska, Tijana Glisic, Sanja Kostic, Nemanja Stojkovic, Nata Joksimovic, Mileva Bascarevic, Aleksandra Bozovic, Lewis Elvin, Ajibola Onifade, Keith Siau, Elizaveta Koriakovskaia, Vladimir Milivojevic

“…Autocrine and endocrine proinflammatory cytokines (TNF-alpha, IL-6), as well as systemic endotoxemia stemming from impaired intestinal permeability, contribute to myocardial remodeling and fibrosis, which further compromise the contractility and relaxation of the heart. …”
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Process Optimization and Antioxidant Activity Analysis of White Kidney Bean Polypeptides Prepared by Composite Strain Fermentation by Sinan LI, Meng WANG, Yu AN, Qing WANG, Kaiyuan XU, Jia WANG, Zhihui ZHANG, Xi WANG, Ying WANG, Lu ZHANG

“…At the end point of intestinal digestion 240 min, the DPPH free radical clearance rate and ABTS+ free radical clearance rate were 84.29% and 77.34%, respectively. …”
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Diverse Profiles of Toll-Like Receptors 2, 4, 7, and 9 mRNA in Peripheral Blood and Biopsy Specimens of Patients with Celiac Disease by Haniye Ghasiyari, Mohammad Rostami-Nejad, Davar Amani, Kamran Rostami, Mohamad Amin Pourhoseingholi, Hamid Asadzadeh-Aghdaei, Mohammad Reza Zali

“…Therefore, the aim of this study was to investigate the TLRs 2, 4, 7, and 9 gene expressions in both peripheral blood and intestinal mucosa of patients with celiac disease compared to healthy control (HC). …”
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