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2361
Fecal propionate is a signature of insulin resistance in polycystic ovary syndrome
Published 2025-01-01“…ObjectiveTo investigate the roles of fecal short-chain fatty acids (SCFAs) in polycystic ovary syndrome (PCOS).MethodsThe levels of SCFAs (acetate, propionate, and butyrate) in 83 patients with PCOS and 63 controls were measured, and their relationships with various metabolic parameters were analyzed. Intestinal microbiome analysis was conducted to identify relevant bacteria. …”
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2362
PANoptosis in Bacterial Infections: A Double-Edged Sword Balancing Host Immunity and Pathogenesis
Published 2025-01-01“…We also discuss the dual roles of PANoptosis in bacterial infectious diseases, including sepsis, pulmonary infections, and intestinal infections. Elucidating the molecular mechanisms underlying PANoptosis and how bacteria manipulate this pathway offers critical insights into host–pathogen interactions. …”
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2363
Bactericidal/Permeability-Increasing Protein (BPI), a Novel Antimicrobial Molecule in Human Breast Milk with Immune Potential
Published 2025-01-01“…Using BPI at concentrations typical of colostrum, we observed that it reduces the growth of two distinct <i>E. coli</i> strains, enhances the uptake of these bacteria by monocytes, and suppresses the secretion of the proinflammatory cytokine interleukin (IL)-8 in infected intestinal cells. These findings suggest that BPI transferred via colostrum from mother to newborn may play a significant role in providing antimicrobial and anti-inflammatory protection during the early stages of life.…”
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2364
New horizons in the treatment of psoriasis: Modulation of gut microbiome
Published 2025-01-01“…The novel concept of the gut-skin axis delves into how skin diseases and the microbiome interact through inflammatory mediators, metabolites, and the intestinal barrier. Elucidating the effects of the gut microbiome on skin health could provide new opportunities for developing innovative treatments for dermatological diseases. …”
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2365
The Effects of Astaxanthin on Metabolic Syndrome: A Comprehensive Review
Published 2024-12-01“…These mechanisms primarily involve regulating signal transduction, transport, or metabolic pathways within the body, as well as influencing intestinal microbiota and metabolites, thereby exerting positive effects on metabolism and inhibiting the occurrence of MS. …”
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2366
The Role of Cell Surface Architecture of Lactobacilli in Host-Microbe Interactions in the Gastrointestinal Tract
Published 2013-01-01“…In recent years, multiple cell surface-associated molecules have been implicated in the adherence of lactobacilli to the GIT lining, immunomodulation, and protective effects on intestinal epithelial barrier function. Identification of the relevant bacterial ligands and their host receptors is imperative for a better understanding of the mechanisms through which lactobacilli exert their beneficial effects on human health.…”
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2367
A Pancreatic Head Tumor Arising as a Duodenal GIST: A Case Report and Review of the Literature
Published 2014-01-01“…Gastrointestinal stromal tumors (GISTs) are rare mesenchymal tumors of the gastrointestinal tract that originate from the intestinal cells of Cajal (ICC) (Fletcher et al., 2002). …”
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2368
Options of conservative treatment at acute adhesive smallintestinal obstruction
Published 2013-10-01“…In 188 patients endoscopic nasointestinal decompression of gastro-intestinal tract was carried out. Due to inefficiency of therapy 269 patients were operated urgently. …”
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2369
Golden berry fruit modulates inflammation in LPS-stimulated RAW 264.7 macrophages and the DSS-induced acute colitis model
Published 2025-02-01“…Our results suggest that consistently consuming golden berries could benefit intestinal inflammation.…”
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2370
Porphyra haitanensis polysaccharide (PH) attenuates cell hyperplasia via remodeling the cross-talk between Hippo/YAP and mTOR pathways
Published 2023-03-01“…The purified PH was first characterized by Fourier-transform infrared spectroscopy. Then an intestinal epithelial cell model was established, in which PH significantly suppressed cell hyperplasia. …”
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2371
Inflammation, impaired motor function and visceral hypersensitivity: the main mechanisms of functional disorders of the gastrointestinal tract (materials of the Expert Council and...
Published 2022-05-01“…The pathogenesis of the most common functional diseases of the gastrointestinal tract — functional dyspepsia (FD) and irritable bowel syndrome (IBS) is multifactorial and includes motor disorders of various parts of the gastrointestinal tract, visceral hypersensitivity, changes in the intestinal microbiome, impairment of the permeability of the protective barrier, low-grade inflammation of the gastrointestinal mucosa, etc. …”
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2372
Unraveling the microbial mysteries: gut microbiota’s role in ulcerative colitis
Published 2025-02-01“…Additionally, the role of extra-intestinal microbiota in UC pathogenesis is explored, which has been less studied but is gaining attention. …”
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2373
Sinigrin Encapsulation in Liposomes: Influence on In Vitro Digestion and Antioxidant Potential
Published 2021-11-01“…Liposomes were shown to inhibit the digestion of sinigrin in both human gastric and intestinal juices, clearly enabling its prolonged release. …”
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2374
Characterization of Zebrafish von Willebrand Factor Reveals Conservation of Domain Structure, Multimerization, and Intracellular Storage
Published 2012-01-01“…Larval expression is in the pharyngeal arches, yolk sac, and intestinal epithelium. These results provide a foundation for continued study of zebrafish Vwf that may further our understanding of the mechanisms of VWD.…”
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2375
Evaluating passive immunity in piglets from sows vaccinated with a PEDV S protein subunit vaccine
Published 2025-01-01“…Piglets from the subunit vaccine group exhibited lower viral shedding, reduced clinical symptoms, and minimal intestinal lesions. These findings suggest that the PEDV S protein subunit vaccine provides enhanced immunity and protection against PEDV, making it a promising candidate for preventing PEDV infections in swine.…”
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2376
Research of Inonotus obliquus Oligosaccharide in Prevention of Hyperlipidemia
Published 2021-01-01“…The mechanism of IOP-2A in preventing hyperlipidemia was obtained from the perspective of mouse intestinal flora.…”
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2377
Rebamipide during chronic gastritis: <i>H. pylori</i> eradication therapy and restoration of gastric mucosa barrier function
Published 2024-01-01“…During atrophic gastritis, long-term treatment with rebamipide has resulted in reduction of degree of atrophy and intestinal metaplasia. Effectiveness of rebamipide during erosive gastritis, for treatment and prevention of stomach and duodenum disorders associated with nonste- roidal anti-inflammatory drugs is proven. …”
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2378
Spray-Dried Microencapsulation of Oregano (Lippia graveolens) Polyphenols with Maltodextrin Enhances Their Stability during In Vitro Digestion
Published 2022-01-01“…During the gastrointestinal simulation, a stability of 85% was determined in the intestinal stage. Microencapsulation technology by spray drying is an excellent selection to stabilize and protect bioactive compounds of oregano and promote its use as a functional ingredient.…”
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2379
Probiotics fermentation enhanced the bioactive properties of Gnaphalium affine water extract and improved regulation ability of gut microbiota
Published 2025-01-01“…Additionally, the G. affine fermented beverages promoted the growth of intestinal probiotics such as Lactobacillus, Bifidobacterium, while inhibiting pathogens like Clostridium, Shigella. …”
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2380
Purification, Physicochemical Properties, and Epitope Analysis of Sarcoplasmic Calcium-Binding Protein from Penaeus vannamei
Published 2025-01-01“…SCP had strong stability against intestinal fluid digestion, but poor stability against gastric fluid digestion. …”
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