From gut to liver: Exploring the crosstalk between gut-liver axis and oxidative stress in metabolic dysfunction-associated steatotic liver disease by Mi Zhou, Jianyu Lv, Xinli Chen, Yujie Shi, Guanqun Chao, Shuo Zhang

“…Our analysis reveals several key findings: (1) Bile acid dysregulation can trigger oxidative stress through enhanced ROS production in hepatocytes and Kupffer cells, leading to mitochondrial dysfunction and lipid peroxidation; (2) Gut microbiota dysbiosis disrupts intestinal barrier function, allowing increased translocation of endotoxins like LPS, which activate inflammatory pathways through TLR4 signaling and promote oxidative stress via NADPH oxidase activation; (3) The redox-sensitive transcription factors NF-κB and Nrf2 serve as crucial mediators in the gut-liver axis, with NF-κB regulating inflammatory responses and Nrf2 orchestrating antioxidant defenses; (4) Oxidative stress-induced damage to intestinal barrier function creates a destructive feedback loop, further exacerbating liver inflammation and disease progression. …”
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Curcumin Improves Epithelial Barrier Integrity of Caco-2 Monolayers by Inhibiting Endoplasmic Reticulum Stress and Subsequent Apoptosis by Xinxin Zhou, Mengting Ren, Jinpu Yang, Hanghai Pan, Mosang Yu, Feng Ji

“…Furthermore, curcumin administration greatly blocked the protein kinase-like endoplasmic reticulum kinase- (PERK-) eukaryotic translation initiation factor 2α- (eIF2α-) activating transcription factor 4- (ATF4-) CHOP signaling pathway. Curcumin enhanced intestinal epithelial barrier integrity in the in vitro coculture model by upregulating TJ protein expressions and reducing intestinal epithelial cell apoptosis. …”
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Alternations of the gut microbiota and the Firmicutes/Bacteroidetes ratio after biologic treatment in inflammatory bowel disease by Yu-Chieh Tsai, Wei-Chen Tai, Chih-Ming Liang, Cheng-Kun Wu, Ming-Chao Tsai, Wan-Hsiang Hu, Pao-Yuan Huang, Chien-Hung Chen, Yuan-Hung Kuo, Chih-Chien Yao, Seng-Kee Chuah

“…The aim of our study was to analyze the intestinal microbiota composition in IBD across different severity levels and the impact of biologic therapy on microbiota modulation. …”
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Brain-Gut Interactions in Inflammatory Bowel Disease: Mechanisms of Anorexia in Animal Models of Experimental Colitis by Harvey P Weingarten

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Novel Targets for Anti-Inflammatory Therapy in Inflammatory Bowel Disease by John L Wallace

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Irritable Bowel Syndrome: New Approaches to Its Pharmacological Management by Gervais Tougas

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Ayude a su sistema digestivo: Entendiendo la microbiota y los prebióticos by Wendy J. Dahl, Volker Mai

“…Esto se conoce como nuestra flora intestinal. This 2-page fact sheet was written by Wendy J. …”
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Disseminated Tuberculosis Mimicking as Crohn’s Disease in a Paediatric Patient by Elizabeth Feenstra, Yentl Driesen, Nicolette Moes, Nathalie Jouret, Koen Vanden Driessche

“…In this report, we present a case of disseminated tuberculosis in an 11-year-old boy with intestinal followed by pulmonary involvement. The diagnosis was delayed for several weeks due to the clinical picture which was mimicking Crohn’s disease, the known difficulties in diagnostic tests and the improvement on meropenem. …”
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Glandular Cystitis. Case presentation by Nelson Cuéllar Suárez, Ives de la Caridad Otero Pérez, Heydisandy Peña Martín

“…Glandular Cistitis is an infrequent proliferative lesion, it is composed of glandular structures , columnar and mucin-secreting intestinal cells.. It is located inside the bladder mucosa and submucosa. …”
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A Comprehensive Review and Update on the Pathogenesis of Inflammatory Bowel Disease by Qingdong Guan

“…Inflammatory bowel disease (IBD) is a chronic and life-threating inflammatory disease of gastroenteric tissue characterized by episodes of intestinal inflammation. The pathogenesis of IBD is complex. …”
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Diet with decreased content of fermentable oligo-, diand monosaccharides and polyols (low FODMAP-diet) in treatment of irritable bowel syndrome by I. L. Khalif, I. A. Tishaeva

“…Short­chain carbohydrates cause increased colonic gas production, influence large intestinal motility, exert osmotic effect that promotes development of IBS symptoms. …”
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Modern radiology in gastroenterology (Аccording to the 19-th Russian gastroenterological week data) by Z. A. Lemeshko

“…Application of radiological methods at detection and differential diagnostics of diseases of the liver, gallbladder, the pancreas, the spleen, gastro-intestinal tract, as well as for patients follow-up and at noninvasive interventions is reflected.Conclusion. …”
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Nonceliac Diaphragm Disease of the Duodenum by Hugh J Freeman

“…Further studies are needed to evaluate potential toxicity or protective effects of different ethnic diets and their relationship with the development of different intestinal diseases.…”
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Hashish Body Packing: A Case Report by Manuel Jesus Soriano-Perez, Jose Luis Serrano-Carrillo, Inmaculada Marin-Montin, Alfonso Cruz-Caballero

“…Body packers may present to the emergency department because of drug toxicity, intestinal obstruction, or more commonly, requested by law-enforcement officers for medical confirmation or exclusion of suspected body packing.…”
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Ayude a su sistema digestivo: Entendiendo la microbiota y los prebióticos by Wendy J. Dahl, Volker Mai

“…Esto se conoce como nuestra flora intestinal. This 2-page fact sheet was written by Wendy J. …”
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An Unusual Cardiac Manifestation in Autosomal Dominant Polycystic Kidney Disease by Fausta Catapano, Stefano Pancaldi, Carlo Pace Napoleone, Lucia Barbara De Sanctis, Gaetano Gargiulo, Giuseppe Emiliani, Antonio Santoro

“…Connective tissue defects, including cerebral aneurysm, meningeal diverticula, abdominal wall hernias, intestinal diverticula, and cardiac valvular abnormalities, are widely known manifestations. …”
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Discussion of the problem of functional constipation and irritable bowel syndrome in the reports of the International Congress on Neurogastroenterology and Motility (Bologna, 2012) by A. A. Sheptulin, M. A. Vize-Khripunova

“…Currently the new pathogenic mechanisms of the irritable bowel syndrome (IBS) are under active study: the role of the infection, the violation of the intestinal mucosa permeability, the immune shifts, the reduction in the bile acids resorption etc.Conclusion. …”
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Increased Cell Proliferation in Chronic Helicobacter pylori Positive Gastritis and Gastric Carcinoma – Correlation between Immuno-Histochemistry and Tv Image Cytometry by Erika Szaleczky, László Prónai, Béla Molnár, Lajos Berczi, János Fehér, Zsolt Tulassay

“…We compared the cell proliferation activity of H. pylori positive and negative gastric epithelial biopsies in chronic gastritis with and without intestinal metaplasia (IM) and gastric cancer by the expression of proliferation cell nuclear antigen (PCNA) and Tv image cytometry, and assessed the effect of H. pylori eradication on the cell proliferation rate in the gastric epithelium.…”
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Associations between prior healthcare use, time to diagnosis, and clinical outcomes in inflammatory bowel disease: a nationally representative population-based cohort study by Alex Bottle, Sonia Saxena, Richard C G Pollok, Jonathan Blackwell, Irene Petersen, Hanna Creese, Nishani Jayasooriya, Richard CG Pollok

“…For CD, >2 consultations were associated with intestinal surgery (adjusted HR (aHR)=2.22, 95% CI 1.45 to 3.39) and subsequent CD-related hospitalisation (aHR=1.80, 95% CI 1.29 to 2.50). …”
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Mixed Adenoneuroendocrine Carcinoma Causing Colonic Intussusception by Marina Morais, André Costa Pinho, Ana Marques, Joanne Lopes, Alexandre Duarte, Pedro Correia da Silva, José Manuel Lopes, J. Costa Maia

“…Colonic intussusception is a rare cause of intestinal obstruction in adults and is caused by a malignant lesion in about 70% of cases. …”
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