Adult Onset Still’s Disease: A Case Report with a Rare Clinical Manifestation and Pathophysiological Correlations by Katerina M. Antoniou, George A. Margaritopoulos, Ioannis Giannarakis, Christianna Choulaki, Nikos Fountoulakis, Nikos M. Siafakas, Prodromos Sidiropoulos

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Spontaneous Pneumomediastinum due to Anti-Melanoma Differentiation-Associated Protein 5 Requiring a Bilateral Lung Transplant by Amrit Singh Jhajj, James Hok Shun Yeung, Fergus To

“…Anti-melanoma differentiation-associated protein 5 (anti-MDA5) is a subset of dermatomyositis associated with respiratory complications, in which rapidly progressive interstitial lung disease (RPILD) is commonly cited, and spontaneous pneumomediastinum (SPM) is a rare complication. …”
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Bone Mineral Density is Decreased in Patients with Systemic Sclerosis and Correlates With Serum Intact Parathormone Levels: A Cross-Sectional Study by Shefali Sharma, Aadhaar Dhooria, Tulika Singh, Varun Dhir, Arghya Chattopadhyay, Debashish Mishra, Sanjay Jain

“…Results: 100 patients were included (89 women). Interstitial lung disease and pulmonary arterial hypertension were seen in 48 and 18 patients, respectively. …”
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Delays in Diagnosis of Pulmonary Lymphangitic Carcinomatosis due to Benign Presentation by Swati Pandey, Shishir Ojha

“…The diagnosis of lymphangitic carcinomatosis is challenging due to the manifestation of nonspecific symptoms and radiographic abnormalities that bear similarity to those of interstitial lung disease. Herein, we report the case of a 53-year-old woman diagnosed with lymphangitic carcinomatosis from metastatic gastric adenocarcinoma, 3 months after her initial presentation.…”
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A Case of Anti-SAE1 Dermatomyositis by Max de Vries, Marco W. J. Schreurs, Els J. M. Ahsmann, Marcela Spee-Dropkova, Faiz Karim

“…A 61-year-old woman presented with progressive shortness of breath, arthralgia, heliotrope rash, Gottron’s papules, and erythematous rash. She had an interstitial lung disease (ILD) with a significant decrease in lung function. …”
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Steroids and/or Cytotoxic Agents Should Be Used Early in the Management of Patients with IPF -- The Pro Argument by Sat Sharma

“…respiratory bronchiolitis interstitial lung disease, acute interstitial pneumonitis, nonspecific interstitial pneumonitis and cryptogenic organizing pneumonitis or bronchiolitis obliterans organizing pneumonia (1). …”
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Pulmonary hypertension associated with connective tissue disease by Srinivas Rajagopala, Molly Mary Thabah

“…CTDs may cause PH due to several mechanisms; pulmonary arterial hypertension, associated interstitial lung disease, neuromuscular disease, and/or sleep disordered breathing leading to hypoxia, associated thromboembolic PH, and pulmonary venous hypertension due to left ventricular dysfunction. …”
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Hypersensitivity Pneumonitis: Challenges of a Complex Disease by Diana Calaras, Aliona David, Eirini Vasarmidi, Katerina Antoniou, Alexandru Corlateanu

“…Hypersensitivity pneumonitis (HP) is a complex interstitial lung disease caused by chronic inhalation of a wide variety of antigens in susceptible and sensitized individuals, commonly associated with an occupational exposure. …”
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Evaluation of Inflammatory Cytokine Secretion by Human Alveolar Macrophages by J. E. Losa García, F. M. Rodríguez, M. R. Martín de Cabo, M. J. García Salgado, J. P. Losada, L. G. Villarón, A. J. López, J. L. P. Arellano

“…Human AMs were collected by bronchoalveolar lavage (BAL) from four healthy controls and 13 patients with diffuse interstitial lung disease (five cases of sarcoidosis, three of hypersensitivity pneumonitis and five of idiopathic pulmonary fibrosis). …”
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Clinical and Immunological Characteristics of Elderly Onset Rheumatoid Arthritis by LI Zhengfang, WU Chanyuan, MA Mengsi, LI Tingting, WU Xue, MENG Xinyan, ZHANG Sha, WU Lijun

“…EORA is prone to interstitial lung disease, anemia and high inflammation, and the level of peripheral blood NK cells is higher.…”
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Desquamative interstitial pneumonia: If there is smoke there is fire by Amit Panjwani, Husain Kadhem, Saadeya Naji Abdulkarim, Umesh Nabar

“…Desquamative interstitial pneumonia (DIP) is a rare type of idiopathic interstitial lung disease (ILD) predominantly seen in smokers. …”
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Spontaneous Pneumomediastinum from Running Sprints by Joseph W. Turban

“…Underlying lung conditions are associated with increased incidence of SPM, including asthma, interstitial lung disease, pneumonia, bullous lung, and radiation therapy for lung cancer. …”
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PL-7 Antisynthetase Syndrome in Association with Sjögren’s, Systemic Lupus Erythematosus, and Rheumatoid Arthritis by Mehrin Jawaid, Yael Ross, Mohammad Kamran

“…She was eventually diagnosed with Sjögren’s/SLE/RA overlap with PL-7 ASS with interstitial lung disease (ILD). ILD was discovered after complaints of pleuritic chest pain with subsequent workup with coronary computed tomography (CT) revealing pulmonary fibrosis. …”
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Pulmonary Complications of Azanucleoside Therapy in Patients with Myelodysplastic Syndrome and Acute Myelogenous Leukemia by Manuel Molina, Sarvari Yellapragada, Martha Mims, Effie Rahman, Gustavo Rivero

“…We present an 89-year-old female with MDS derived AML who developed fatigability, hypoxemia, and bilateral lung infiltrates indicating interstitial lung disease after 11 cycles of azanucleoside. …”
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Cardiopulmonary Exercise Testing: Deciphering Cardiovascular Complications in Systemic Sclerosis by Ailia Giubertoni, Mattia Bellan, Luca Cumitini, Giuseppe Patti

“…A high proportion of patients with SSc experience pulmonary arterial hypertension (PAH), interstitial lung disease, or myocardial involvement, all of which can lead to exercise intolerance. …”
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Mycobacterium intracellulare Infection Mimicking Progression of Scleroderma by Simon Krabbe, Merete Engelhart, Sören Thybo, Søren Jacobsen

“…The patient was diagnosed with scleroderma based on puffy fingers that developed into sclerodactyly, abnormal nail fold capillaries, interstitial lung disease, Raynaud’s phenomenon, esophageal dysmotility, and positivity for rheumatoid factor and anti-SSA antibodies. …”
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Development of Two Types of Skin Cancer in a Patient with Systemic Sclerosis: a Case Report and Overview of the Literature by Firdevs Ulutaş, Erdem Çomut, Veli Çobankara

“…She is still on rituximab treatment with stable interstitial lung disease as indicated by pulmonary function tests and high-resolution chest computed tomography. …”
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Organizing Pneumonia Preceding Rheumatoid Arthritis by Yoshiaki Kinoshita, Atsuhiko Sakamoto, Kouko Hidaka

“…Rheumatoid arthritis patients are susceptible to interstitial lung disease, and joint manifestations of rheumatoid arthritis usually precede lung involvements by several years. …”
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Promising Neutrophil-Associated Biomarkers in Lung Diseases of Patients with Antisynthetase Syndrome and Dermatomyositis by Lei Liu, Jundi Wang, Peiyu Zhang, Wenjia Sun, Xiuliang Zhu, Xiujuan Sun, Jing Xue, Huaxiang Wu

“…Our study identified the neutrophil-associated biomarkers MPO, NE, and IL-6 as promising indicators with different suggestive roles in respiratory infections and interstitial lung diseases in patients with ASS and DM.…”
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New Onset of Dermatomyositis/Polymyositis during Anti-TNF-α Therapies: A Systematic Literature Review by Alexandra Maria Giovanna Brunasso, Werner Aberer, Cesare Massone

“…In 6 patients antisynthetase antibodies were detected and other clinical findings as interstitial lung disease (ILD) were recorded. Improvement of DM/PM after anti-TNF suspension (with the concomitant use of other immunosuppressors) was recorded in 94% of cases. …”
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