GPX3 as a Novel and Potential Therapeutic Target in the Shared Molecular Mechanisms of Traumatic Brain Injury and Parkinson’s Disease by Wang Y, Fang J, Yuan Q, Yu J, Hu J

“…The glutathione peroxidase 3 (GPX3) gene emerged as a pivotal hub gene, with its expression significantly altered in both TBI and PD datasets.Conclusion: This study underscores the critical role of GPX3 in the molecular intersection of TBI and PD, suggesting it as a novel and potential therapeutic target, offering new insights into potential therapeutic strategies.Keywords: traumatic brain injury, Parkinson’s disease, bioinformatics, oxidative stress, mitochondrial dysfunction, neurodegenerative diseases…”
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Research on path planning for coal mine rescue robots by ZHU Hongbo, YIN Hongliang

“…Next, a correction factor is incorporated into the cost function of the Bidirectional A* algorithm to ensure that the forward and backward search paths intersect, preventing them from diverging. Additionally, a dynamic weighting factor is added to the estimated cost function to eliminate irrelevant expanded nodes during pathfinding, thus improving search efficiency. …”
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Grouting Mechanism in Water-Bearing Fractured Rock Based on Two-Phase Flow by Bo Ren, Wenqiang Mu, Bingyou Jiang, Guofeng Yu, Lianchong Li, Tingshuang Wei, Yunchun Han, Diancai Xiao

“…The optimization scheme of grouting was put forward, which adopted multiple grouting holes in the long side, and grouting in different directions and periods to avoid the possible problems of multihole intersection. The rationality and effectiveness of the proposed optimization method were verified through the calculation of water yield and analysis of cement composition from the drilling core in the grouted zone. …”
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Recent trends in research on the role of cholesterol in leukemia: a bibliometric and visualization study by Huijuan Lv, Ke Lu, Ximing Wang, Yanfang Zhang, Mengqi Zhuang, Jing Li, Keli Su, Wen Gao

“…Further exploration at the intersection of cholesterol metabolism and leukemia requires multidisciplinary collaboration.ConclusionThis bibliometric study delineates the evolving research landscape on cholesterol’s role in leukemia, pinpointing emerging trends and future research directions to inform effective therapeutic strategies.…”
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Multimodal Imaging of Patients With Gliomas Confirms C-MET PET as a Complementary Marker to MRI for Noninvasive Tumor Grading and Intraindividual Follow-Up After Therapy by Kai R. Laukamp MD, Florian Lindemann PhD, Matthias Weckesser MD, Volker Hesselmann MD, Sandra Ligges PhD, Johannes Wölfer MD, Astrid Jeibmann MD, Bastian Zinnhardt PhD, Thomas Viel PhD, Michael Schäfers MD, Werner Paulus MD, Walter Stummer MD, Otmar Schober PhD, MD, Andreas H. Jacobs MD

“…The computer software “visualization and analysis framework volume rendering engine (Voreen)” was used for analysis of extent and intersection of tumor compartments. Binary logistic regression models were developed to differentiate between World Health Organization (WHO) tumor types/grades. …”
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Taung and beyond: The mining history, geology and taphonomy of Australopithecus in South Africa by Rieneke Weij, Stephanie E. Baker, Tara R. Edwards, Job Kibii, Georgina Luti, Robyn Pickering

“…The South African Fossil Hominid sites provide a unique opportunity to expand our understanding of the intersection between human evolution and changing environmental conditions, as the karstic landscape and remnant cave systems preserve both fossils and sedimentary archives of past environmental change. …”
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Discrete Element Modeling on Mechanical Behavior of Heterogeneous Rock Containing X-Shaped Fissure under Uniaxial Compression by Ming Chen, Jian Liu, Zhengyong Xie, Jianjun Liu, Xunjian Hu, Bingyang Li, Yue Cen

“…Based on the experimental results of an intact rock specimen under uniaxial compression, particle flow code (PFC2D) was adopted to carry out a discrete element modeling (DEM) for the mechanical behavior of heterogeneous rocks containing X-shaped fissures (two intersecting symmetric single fissures) under uniaxial compression. …”
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Work–health–personal life conflicts in naive patients with chronic hepatitis B receiving initial treatment in China: a qualitative study by Li Zhang, Ying Chen, Ying Li, Hongmei Wang, Lin Zhu, Xiaoyang Lu, Yingjing Zheng, Donald Patrick, Fengjiao Xu, Mengna Song, Xiao Cheng, Boyan Chen

“…Participants were within the age range of 19-57 years, and the average age was 36.03 (SD=9.56) years.Results Participants noted that having CHB influenced their daily life and intersected with work and personal roles, therefore causing role conflicts. …”
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Trends, outcomes and knowledge gaps in mobile apps for reproductive endocrinology and infertility: a scoping review protocol by Alba Regina de Abreu Lima, Emerson Roberto dos Santos, Aline Russomano de Gouvêa, Natália Almeida de Arnaldo Silva Rodriguez Castro, João Daniel de Souza Menezes, Matheus Querino da Silva, Helena Landin Gonçalves Cristóvão, Cíntia Canato Martins, Jéssica Gisleine de Oliveira, Patrícia da Silva Fucuta, Alexandre Lins Werneck, Gerardo Maria de Araújo Filho, Heloisa Cristina Caldas, Vânia Maria Sabadoto Brienze, Júlio César André, Antônio Hélio Oliani

“…This scoping review distinguishes itself by systematically mapping and synthesising evidence on mobile apps specifically for reproductive endocrinology and infertility, unlike previous reviews that may not have focused exclusively on this intersection. This review aims to analyse recent trends, identify outcomes used to assess usability and highlight knowledge gaps.Methods and analysis This scoping review will adhere to the methodological frameworks outlined by Arksey and O'Malley and Levac et al, alongside the Joanna Briggs Institute’s recommendations. …”
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Comorbidities and neurosurgical interventions in a cohort with connective tissue disorders by Ilene S. Ruhoy, Paolo A. Bolognese, Jared S. Rosenblum, Randall A. Dass, Navdeep S. Nayyer, Navdeep S. Nayyer, Jeffrey D. Wood, Jeffrey D. Wood, John B. Biggins, John B. Biggins

“…We evaluated relationships between diagnoses and surgical interventions by multivariate correlation and intersection plots using the UpSetR package.ResultsOf 759 individuals, we excluded 42 based on incomplete data. …”
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Screening of necroptosis-related genes and evaluating the prognostic capacity, clinical value, and the effect of their copy number variations in acute myeloid leukemia by Dake Wen, Ru Yan, Lin Zhang, Haoyang Zhang, Xuyang Chen, Jian Zhou

“…Methods Necroptosis-related differentially expressed genes (NRDEGs) were identified after intersecting differentially expressed genes (DEGs) from the Gene Expression Omnibus(GEO) database with NRGs from GeneCards, the Molecular Signatures Database (MSigDB) and literatures. …”
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The proneural transcription factor Atoh1 promotes odontogenic differentiation in human dental pulp stem cells (DPSCs) by Camila Sabatini, Huey-Jiun Lin, Galib Ovik, Richard Hall, Techung Lee

“…The functional versatility of Atoh1 prompted us to test the possibility that Atoh1 may intersect the dental pulp stem cell (DPSC) gene regulatory network governing odontogenic differentiation. …”
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Analysis of the mechanism of Zangjiangzhi capsule in the treatment of hyperlipidemia based on its ingredients identified by UHPLC-Q-Exactive-Orbitrap-MS by Changting He, Yuling Zhao, Yongchun Huang, Yudong Su, Shoude Zhang

“…Among them, 158 targets intersected with the HLP target network. Network pharmacology analysis showed that MAPK1, PPAR-α, RXRA, HSP90AA1, PIK3R1, AKT1, PIK3CA, IL6, TNF, and ESR1 are the key targets of action. …”
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The impact of the COVID-19 pandemic on the research activity and working experience of clinical academics, with a focus on gender and ethnicity: a qualitative study in the UK by Carmen Soto, Jessica Elizabeth Morgan, Paul Crampton, Paul Alexander Tiffin, Gabrielle M Finn, Amelia Kehoe, Ellie Taylor, John AG Buchanan, Abisola Olatokunbo Balogun

“…Participants described differential experiences based upon their gender and ethnicity, noting intersectional identities.Conclusions While there have been some positives afforded to clinical academics, particularly for new avenues of research, COVID-19 has negatively impacted workload, future career intentions and mental health. …”
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Maladie, médecine et migration au prisme de l’écriture migrante sino-française: une contribution à la médecine transculturelle? by Julia Pröll

“…In particular, it is the bicultural and bilingual background of these authors that enables them to evoke – and often also to intersect – different conceptions of illness and health in their texts, a double perspective that encourages a salutary relativization of any (medical) paradigm that claims to be dominant. …”
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Perspectives on which health settings geriatricians should staff: a qualitative study of patients, care providers and health administrators by Eric Kai-Chung Wong, Andrea C. Tricco, Wanrudee Isaranuwatchai, David M. J. Naimark, Sharon E. Straus, Joanna E. M. Sale

“…Acute care was reported to be most important by some because no other care provider has the intersection of acute medicine skills with geriatric training. …”
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Comprehensive Analysis of Competing Endogenous RNA Network Focusing on Long Noncoding RNA Involved in Cirrhotic Hepatocellular Carcinoma by Yuli Zhang, Dinggui Chen, Miaomiao Yang, Xianfeng Qian, Chunmei Long, Zhongwei Zheng

“…A total of 74 lncRNAs, 36 intersection miRNAs, and 949 mRNAs were differentially expressed in cirrhotic HCC samples compared with cirrhosis samples. …”
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Social and economic impacts of non-communicable diseases by gender and its correlates: a literature review by Concepción García-Morales, Ileana Heredia-Pi, Carlos M. Guerrero-López, Emanuel Orozco, Enai Ojeda-Arroyo, Gustavo Nigenda, Edson Serván-Mori

“…Abstract Background Tackling social impacts derived from gender disparities is a pathway to universal health coverage (UHC). Gender intersects with other factors behind social and health inequalities, exacerbates them and influences health systems’ performance. …”
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Bioinformatics insights into mitochondrial and immune gene regulation in Alzheimer's disease by Tian Meng, Yazhou Zhang, Yuan Ye, Hui Li, Yongsheng He

“…Methods In this study, the intersection of the differentially expressed genes (DEGs) from the GSE109887 cohort, immune-related genes (IRGs) obtained from WGCNA analysis, and mitochondria-related genes (MRGs) was taken to identify mitochondria–immune-related genes (MIRGs). …”
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Identification and validation of glucose metabolism-related gene signature in endometrial cancer by Juan Jiang, Nan Xia, Mei Yang, Ping Qiu, Wei Zhu, Jing Chen, Jiamei Zhu

“…Glucose metabolism-related DEGs (GMR-DEGs) were then derived by intersecting these DEGs with GMRGs. A prognostic signature for EC was developed through the Least Absolute Shrinkage and Selection Operator (LASSO) regression and univariate Cox analysis. …”
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