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Repetitive stability study of remdesivir/cyclodextrin complex on the international space station
Published 2025-02-01“…Therefore, we investigated the stability of an anti-Covid drug formulation, Remdesivir (RDV) sulfobutylether-beta-cyclodextrin (SBECD) complex, in two separate flight experiments on the International Space Station (ISS). While HPLC/MS studies revealed no degradation of the cyclodextrin excipient in any of the samples investigated in both missions, RDV purity analysis of the RDV/SBECD complex after the first mission revealed different stabilities and altered degradation in space and on Earth. …”
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Hot pants: The emerging field of exercise mimetics, from hospital beds to the international space station
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Conception of a compact flow boiling loop for the International Space Station- First results in parabolic flights
Published 2023-02-01“…The design of a pipe flow boiling experiment for the International Space Station is proposed, taking into account typical weight, power consumption and size constraints. …”
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A Fosmid Cloning Strategy for Detecting the Widest Possible Spectrum of Microbes from the International Space Station Drinking Water System
Published 2012-12-01Subjects: Get full text
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Autonomous Streaming Space Objects Detection Based on a Remote Optical System
Published 2021-12-01“…The video processing result of the pass had demonstrated in the form of centroid coordinates of the International Space Station in the image plane with a timestamps interval of which is 0.2 s.This approach provides an autonomous raw data extraction of a space object for numerical methods for the initial determination of its orbit.…”
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Simulated deep space exposure on seeds utilizing the MISSE flight facility
Published 2025-01-01“…The project tested the Multipurpose Materials International Space Station Experiment—Flight Facility (MISSE-FF) hardware as a platform for exposing biological samples to the space environment outside the International Space Station (ISS). …”
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30 years of CNES parabolic flights for the benefit of the scientific community
Published 2023-01-01“…The use of parabolic flights is complementary to other microgravity carriers, and preparatory to manned space missions onboard the International Space Station and other manned spacecraft, around the Earth or beyond, to the Moon for example.The main advantages of parabolic flights for microgravity investigations are the short turn-around time, the relatively low cost, the flexibility of experimental approach, the possibility of direct intervention by investigators on board the aircraft during and between parabolas, and the possibility of modifying the experiment set-up between flights.…”
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Performance of Gradient-Based Solutions versus Genetic Algorithms in the Correlation of Thermal Mathematical Models of Spacecrafts
Published 2017-01-01“…The case of study used in the comparison is a real space instrument flown aboard the International Space Station.…”
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In situ experiments in microgravity and phase-field simulations of the lamellar-to-rod transition during eutectic growth
Published 2023-02-01“…In recent experiments on the solidification of the binary eutectic alloy succinonitrile-(D)camphor carried out on board of the International Space Station (ISS), a transition from rod to lamellar patterns was observed for low growth velocities. …”
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Observations of Blue Corona Discharges in Thunderclouds
Published 2022-06-01“…Analyzing 3 years of measurements by the Atmosphere‐Space Interactions Monitor on the International Space Station, we find that their distribution in rise time falls into two categories. …”
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The appreciation of the jurisdiction of crimes committed during commercial space flights
Published 2023-06-01“…Thus, the first case emphasises the restricted applicability of criminal jurisdiction on the international space station, which is usually decided by the law of the country of a person’s nationality. …”
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Investigation of endurance of AMg6 alloy under cyclic volumetric thermal deformation
Published 2022-11-01“…A comparative analysis of the calculated endurance of the experimental samples with the actual endurance of the structural material (hard worked alloy AMg6) of a real orbital object such as the «Zarya» module of the international space station shows a discrepancy of no more than 12,5 %.…”
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The analysis of structural fatigue under cyclic temperature loads
Published 2021-12-01“…Linear deformations of the body material of the International Space Station are determined, taking into account heating from solar radiation and cooling, while in the shadow of the Earth. …”
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Transcriptomics analysis reveals potential mechanisms underlying mitochondrial dysfunction and T cell exhaustion in astronauts’ blood cells in space
Published 2025-01-01“…However, the molecular mechanisms underlying spaceflight-induced immune dysregulations are still unclear.MethodsIn this study, blood from eleven crewmembers was collected before and during International Space Station (ISS) missions. Transcriptomic analysis was performed in isolated peripheral blood mononuclear cells (PBMCs) using RNA-sequencing. …”
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The problem of assessing endurance of hull elements of low-flying orbital objects
Published 2024-06-01“…The adequacy of the methodology is verified using the example of depressurization of the housing of the Zarya orbital module of the international space station, made of AMg6 alloy after ≈120,000 cycles of alternating temperature loading. …”
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