Veronicastrum axillare Alleviates Lipopolysaccharide-Induced Acute Lung Injury via Suppression of Proinflammatory Mediators and Downregulation of the NF-κB Signaling Pathway by Quanxin Ma, Kai Wang, Qinqin Yang, Shun Ping, Weichun Zhao, Qiyang Shou, Weimin Zhou, Minli Chen

“…We observed that V. axillare suppressed the mRNA expression of interleukin-1β (IL-1β), IL-6, monocyte chemotactic protein-1 (MCP-1), cyclooxygenase-2 (COX-2), and tumor necrosis factor-α (TNF-α) in RAW264.7 cells challenged with LPS. …”
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Chitooligosaccharides suppress airway inflammation, fibrosis, and mucus hypersecretion in a house dust mite-induced allergy model by Yun-Ho Kim, Chan-Ho Park, Ju Myung Kim, Yeo Cho Yoon

“…Samples of right lung tissue obtained from the experimental animals were used for gene and protein expression analysis, whereas samples of contralateral lung tissue were used for immunohistochemical analysis.ResultsCOS regulated Th1 immunity by inhibiting major cytokines, including inflammatory tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), and interleukin-6 (IL-6), in BEAS-2B cells. …”
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Exploring Antibacterial Activity of Fish Protein Hydrolysate In Vitro Against Vibrio Strains and Disease Resistance to V. harveyi in Turbot (Scophthalmus maximus) by Yuliang Wei, Lu Wang, Yanlu Li, Qiang Ma, Mengqing Liang, Houguo Xu

“…Meanwhile, the expression of some pro-inflammatory cytokines (interleukin-1β [il-1β], il-6, and il-8) was downregulated in the FPH group after the V. harveyi challenge. …”
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miR-197 Participates in Lipopolysaccharide-Induced Cardiomyocyte Injury by Modulating SIRT1 by Miaomiao Liu, Ying Zhang, Xiantong Cao, Tao Shi, Yang Yan

“…LPS restrained viability, the expressions of B-cell lymphoma-2 (Bcl-2) and SIRT1, but promoted apoptosis, LDH release, and levels of interleukin-6 (IL-6), interleukin-1β (IL-1β), acetyl (AC)-p53, BCL2-associated X (Bax), and cleaved caspase-3 in H9c2 cells. miR-197 inhibition reversed the effects of LPS on H9c2 cells. …”
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Psychological Stress Delays Periodontitis Healing in Rats: The Involvement of Basic Fibroblast Growth Factor by Ya-Juan Zhao, Qiang Li, Bai-Xiang Cheng, Min Zhang, Yong-Jin Chen

“…The periodontitis healing condition was assessed, and the expression of interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and bFGF were tested by immunohistochemistry. …”
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MicroRNA-155 Participates in the Expression of LSD1 and Proinflammatory Cytokines in Rheumatoid Synovial Cells by Ziliang Yu, Hao Liu, Jianbo Fan, Feihu Chen, Wei Liu

“…Tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-6 are key proinflammatory cytokines implicated in the pathogenesis of RA. …”
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cAMP analogues downregulate the expression of granulocyte macrophage colony-stimulating factor (GM-CSF) in human bone marrow stromal cells in vitro by G. Bug, J. Aman, C. Huber, C. Peschel, H. G. Derigs

“…The stimulation of granulocyte macrophage-colony stimulating factor (GM-CSF) by interleukin-1 (IL-1) has been shown to be counteracted in different mesenchymal cell systems by cyclic adenosine monophosphate (cAMP) agonists. …”
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Post-traumatic arthritis: overview on pathogenic mechanisms and role of inflammation by Roberta Ramonda, Leonardo Punzi, Anna Scanu, Francesca Oliviero, Roberto Luisetto, Paola Galozzi, Marta Favero

“…Given the relevance of inflammatory reaction, anticytokines therapy, in particular the inhibition of interleukin 1 (IL-1), seems to be the most promising strategy. …”
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Case report: Therapeutic use of bortezomib in a patient with Schnitzler syndrome by Hua Bai, Dongming Zhou, Jinwen Liu, Jie He, Zhou Min, Wenyong Fan, Bing Chen, Yong Xu

“…Schnitzler syndrome (SchS) is a rare acquired systemic autoinflammatory disorder, characterized by chronic urticarial rash and immunoglobulin M (IgM) monoclonal gammopathy. Anti-interleukin-1 (IL-1) therapies have been shown to be more effective in managing the clinical symptoms of SchS compared to anti-IL-6 therapies. …”
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The Role of Serum Cytokines in the Pathogenesis of Hepatic Osteodystrophy in Male Cirrhotic Patients by Ali Riza Soylu, Cengiz Tuglu, Ender Arikan, Tarkan Yetisyigit, Hakan Kunduracılar, Ibrahim Hakki Koker, Gulbin Unsal, Ahmet Huseyin Tezel, Hasan Umit, Sakir Berkarda

“…Although osteopenia frequency between our cirrhotic patients was 20%, there was no difference in T-scores among the controls and other groups. Serum interleukin-1, interleukin-8, and tumor necrosis factor-alpha levels were not different between all groups. …”
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Interleukin-18 Increases TLR4 and Mannose Receptor Expression and Modulates Cytokine Production in Human Monocytes by Luciane Alarcão Dias-Melicio, Reginaldo Keller Fernandes, Daniela Ramos Rodrigues, Marjorie Assis Golim, Angela Maria Victoriano Campos Soares

“…Interleukin-18 is a proinflammatory cytokine belonging to the interleukin-1 family of cytokines. This cytokine exerts many unique biological and immunological effects. …”
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Epac1 Restores Normal Insulin Signaling through a Reduction in Inflammatory Cytokines by Elizabeth Curtiss, Youde Jiang, Li Liu, Claire Hawthorne, Jessica Zhang, Jena J. Steinle

“…We have also published that impaired insulin signaling occurs in the diabetic retina. A reduction in interleukin-1 beta (IL-1β) and tumor necrosis factor alpha (TNFα) by Epac1 could potentially restore normal insulin signal transduction. …”
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Pleiotropic effects of rabeprazole at acid-related diseases by A. V. Zaborovsky, I. V. Mayev, D. N. Andreyev, L. A. Tararina

“…To study association interleukin-1 (IL-1) gene (rs16944), interleukin-6 (IL-6) gene (rs1800795), interleukin-10 (IL-10) gene (rs1800896) polymorphisms with development of acute pancreatitis (AP) in the Russian population. …”
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Effects of White Quinoa Polysaccharide on Regulation of Glucolipid Metabolism in Type 2 Diabetic Mice by Yanqing ZANG, Yingying CHUANG, Changyuan WANG, Yang CAO

“…The intake of WQP also reduced interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) by 21% and 22%, respectively. …”
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A Novel Role for Brain Natriuretic Peptide: Inhibition of IL-1β Secretion via Downregulation of NF-kB/Erk 1/2 and NALP3/ASC/Caspase-1 Activation in Human THP-1 Monocyte by Letizia Mezzasoma, Cinzia Antognelli, Vincenzo Nicola Talesa

“…Interleukin-1β (IL-1β) is a pleiotropic cytokine and a crucial mediator of inflammatory and immune responses. …”
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Investigating the role of hyperexpressed HCN1 in inducing myocardial infarction through activation of the NF-κB signaling pathway by Liang Xiao, Zhang Jie, Luo Ya

“…ELISA kits were used to determine the levels of malondialdehyde, superoxide dismutase, and interleukin-1 beta. The HCN1-OE group exhibited increased apoptosis, elevated ROS, and decreased survival. …”
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Knockdown of PTEN promotes colon cancer progression and induces M2 macrophage polarization in the colon cancer cell environment by Xu Han, Ting Yan, Lina Wang, Bin He, Huaxu Yu

“…Si-PTEN reduced the expression of tumor necrosis factor-alpha (TNF-α), interleukin-1beta (IL-1β), and inducible nitric oxide synthase (iNOS), which upregulated the expression of Arg-1, CD206, CD163, p-p38, JNK, and AP-1 (P-values < 0.05). …”
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Liraglutide Attenuates Hepatic Oxidative Stress, Inflammation, and Apoptosis in Streptozotocin-Induced Diabetic Mice by Modulating the Wnt/β-Catenin Signaling Pathway by Jie Yu, Yuan Zhao, Lingling Xu, Wei Li, Huabing Zhang, Fan Ping, Yuxiu Li

“…Furthermore, a significant increase in the levels of malondialdehyde and inflammatory markers such as tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and interleukin 1β (IL-1β) and the proapoptotic proteins caspase-3 and Bax were observed in the livers of diabetic mice, together with marked increases in antioxidants superoxide dismutase (SOD) and glutathione peroxidase (GPX) as well as antiapoptotic protein Bcl-2, all of which were significantly mitigated by treatment with liraglutide, insulin, and their combinations. …”
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Annexin I and dexamethasone effects on phospholipase and cyclooxygenase activity in human synoviocytes by Annaleise V. Sampey, Paul Hutchinson, Eric F. Morand

“…We studied the effects of a bioactive annexin I peptide, ac 2–26, dexamethasone (DEX), and interleukin-1β (IL-1β) on phospholipase A2 (PLA2) and cyclooxygenase (COX) activities and prostaglandin E2 (PGE2) release in cultured human fibroblast-like synoviocytes (FLS). …”
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Influence of Inflammatory Cytokines IL-1β and IFNγ on Sarcoplasmic Aggregation of p62 and TDP-43 in Myotubes by Bryony McCord, Richard M. Day

“…This study aimed to investigate the effect of IFNγ and interleukin 1-β (IL-1β) on TDP-43 and p62 aggregation in vitro. …”
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