Targeting and editing the second exon of bmp6 gene results in a silver carp with reduced intramuscular bones by Shuang Niu, Xiaohui Li, Cui Feng, Zewen Zhang, Hang Sha, Xiangzhong Luo, Guiwei Zou, Hongwei Liang

“…DEGs identified only in CH-E2 group were significant enrichment in “osteoclast differentiation”, “NF-kappa B signaling pathway” and “cytokine-cytokine receptor interactions”, indicating a specificity unique to CH-E2 group. …”
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Exosomes and their distinct integrins transfer the characteristics of oxaliplatin- and 5-FU-resistant behaviors in colorectal cancer cells by Zeynab Vakili-Ghartavol, Hoda Deli, Amir Shadboorestan, Roxana Sahebnasagh, Elahe Motevaseli, Mohammad Hossein Ghahremani

“…Integrins, as valuable prognostic markers in cancer, have importance in exosome-cell interaction. However, the role of exosome integrins in chemoresistant colorectal cancer remained unclear. …”
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Buffalo whey proteins performance at the oil/water interface: rheology characterization of the interfacial films by Leandro F. Bustos, Víctor M. Pizones Ruiz-Henestrosa, Cecilio Carrera Sánchez, Franco E. Vasile, Oscar E. Pérez

“…This behavior can be explained by considering that the higher the protein concentration, the stronger interactions among BPWC proteins occur. In conclusion, BWPC increased the interfacial pressure to a greater extent than WPC and concomitantly formed films with a higher solid character. …”
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Animal experiments and network pharmacology to explore the anti-inflammatory mechanism of dapagliflozin in the treatment of polycystic ovary syndrome by Yong Liu, He Bai, Huilin Guan, Chunhua Wang, Xueqing Song, Zihao Yong, Xiaomeng Guo, Luxin Li, Zhen Zhang

“…Network pharmacology was used to predict the inflammatory targets and pathways affected by dapagliflozin in treating PCOS, and the potential interactions between dapagliflozin and inflammation-related target proteins were evaluated through molecular docking.Results Our results demonstrated that dapagliflozin treatment significantly improved PCOS symptoms, recovered ovarian morphology and physiological functions, and reduced the apoptosis of ovarian cells after drug intervention. …”
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Etude préliminaire de l'influence des disponibilités alimentaires et des activités humaines sur l’utilisation spatiale de l’habitat par les chimpanzés et les bonobos by Victor Narat, Marie Cibot, Jean Christophe Bokika Ngawolo, Richard Dumez, Sabrina Krief

“…Great apes are endangered due to poaching, deforestation, habitat loss and habitat fragmentation. Studying the interactions between great apes, their environment and local population is necessary for understanding the adaptability of great apes to habitat disturbance and to assess the specific threats in the local context. …”
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Smart packaging tools for selected Indian traditional buffalo milk products: a case for on-package freshness indicators by Narender Raju Panjagari, Ashish Kumar Singh, Sangita Ganguly, Rajan Sharma, Vivek Sharma

“…The selected freshness indicators were characterized and suitably integrated with the closures to effectively detect and interact with the dynamic headspace volatile compounds while storing the packaged product. …”
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Meta-analysis on Studies of Deviant Marketing Behaviors: Past, Present and Future by Zahra Ahmadi Alvar, Davood Feiz, Meysam Modarresi

“…The analysis generated clusters of topics, including Job and Corporate Identity, Customer Orientation and Service Orientation, Consumer Behavior, Sales States and Behaviors, Marketing Interactions, and Neutralization Techniques. It is predicted that in the future years, research on marketing deviant behaviors will increase, and continue its upward and increasing trend. …”
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Identification of potential druggable targets for endometriosis through Mendelian randomization analysis by Peng Chen, Xin Wei, Xiao-Ke Li, Yi-Hang Zhou, Yi-Hang Zhou, Qi-Fang Liu, Ling Ou-Yang

“…Additionally, we conducted a protein-protein interaction (PPI) network as well as functional enrichment analyses to unveil potential associations among target proteins.ResultsMR analysis revealed that a decrease of one standard deviation (SD) in plasma R-Spondin 3 (RSPO3) level had a protective effect on EM (OR = 1.0029; 95% confidence interval (95% CI): 1.0015–1.0043; P = 3.2567e-05; Bonferroni P < 5.63 × 10−5). …”
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Observation on the efficacy of TPO receptor agonists and platelet transfusion in chemotherapy-induced thrombocytopenia in malignant tumors by Huan Hu, Dongmei Lei, Yan Liang

“…Regarding platelet counts, repeated measures analysis of variance showed significant differences in the time effect, group effect, and interaction effect for platelet counts (PLT) among the three groups (P < 0.05). …”
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First evidence of transovarial transmission of Kyasanur Forest disease virus in Haemaphysalis and Rhipicephalus ticks in the wild by Sarah J. Burthe, Bhimanagoud Kumbar, Stefanie M. Schäfer, Bethan V. Purse, Abi T. Vanak, Natrajan Balakrishnan, Richard Hassall, Subhash L. Hoti, Darshan Narayanaswamy, Santoshkumar Potadar, Mujeeb Rahman, Mohammed Mudassar Chanda

“…Empirical data on pathogen-vector-host interactions and incrimination have not been updated since the last century, despite significant local changes in land use and the expansion of KFD to new areas. …”
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Phage-mediated virulence loss and antimicrobial susceptibility in carbapenem-resistant Klebsiella pneumoniae by Yanshuang Yu, Mengzhu Wang, Liuying Ju, Minchun Li, Mengshi Zhao, Hui Deng, Christopher Rensing, Qiu E. Yang, Shungui Zhou

“…These insights advance our understanding of phage-host interactions in clinical settings, potentially inspiring new approaches akin to an “arms race” model to combat multidrug-resistant crises effectively.…”
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POVEIKIS IR ATSAKAS BIOLOGINIUOSE VYKSMUOSE by Jonas Rubikas

“…In biological processes the affect-response dependence can be regarded as taking place at two levels: the first is that of molecular interaction, atomic and linkage exchange, the second is that of cell and individual and organism. …”
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Effect of motivational interviewing to promote advance care planning among palliative care patients in ambulatory care setting: a randomized controlled trial by Helen Yue-Lai Chan, Doris Yin-Ping Leung, Po-Tin Lam, Polly Po-Shan Ko, Raymond Wai-Man Lam, Kin-Shan Chan

“…Generalized estimating equation analyses showed a significant improvement in readiness for advance care planning behaviors in the intervention group compared with the control group at 3 months post-allocation (group-by-time interaction, appointing proxy: β = 0.80; 95% CI, 0.25–1.35; p = .005; discussing with family: β = 0.76; 95% CI, 0.22–1.31; p = .006; discussing with medical doctors: β = 0.86; 95% CI, 0.30–1.42; p = .003; documenting: β = 0.89; 95% CI, 0.36–1.41; p < .001). …”
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Acute effect of endurance exercise on human milk insulin concentrations: a randomised cross-over study by Rebecca Lyng Holm, Mads Holmen, Md Abu Jafar Sujan, Md Abu Jafar Sujan, Guro F. Giskeødegård, Trine Moholdt, Trine Moholdt

“…We determined insulin concentrations in the milk using enzyme-linked immunosorbent assay and compared insulin concentrations after MICT and HIIT with REST using a linear mixed model with time-points and the interaction between time and condition as fixed factors.ResultsWe detected insulin in all 240 samples, with an average concentration of 12.3 (SD 8.8) μIU/mL (range 3.2–57.2 μIU/mL). …”
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ASPECTOS PSICOJURÍDICOS DA SÍNDROME ALCOÓLICA FETAL by Eduardo Jorge Sant'Ana Honorato, Dalila Azevedo da Silva, Eunice Braga Borges dos Santos, Alice Sobral, Daniel Cerdeira de Sousa

“…At that point the family emerges as a protective factor because prevention can start at home with the family where the pregnant women they can be safer, with family watching and meeting their potentialities development needs is also in this context that the psychologist It presents with with its good practice, serving as a link connection between families and public policies to define strategies of integration and inclusion in society and interaction with other professionals. In this study there was no definition if the amount ingested alcohol by pregnant women is relevant to the developing fetus, but it was clear that the complete withdrawal of this substance is of fundamental importance for the prevention of FAS. …”
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Insights into salinity effect on growth of the spotted scat (Scatophagus argus): Exploring the optimum salinity for its culture by Maoliang Su, Zhanquan Feng, Youling Zhong, Zhiyin Ye, Junbin Zhang

“…In view of endocrine modulation, the somatic growth of S. argus juveniles was modulated by cross-talk interactions between GH/IGF-I and cortisol under different salinity conditions.…”
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Isolation and function of a human endothelial cell C1q receptor by M. R. Daha, L. Dunn, R. van den Berg, Y. Muizert-de Lange, A. Gerritsen, L. A. van Es

“…Therefore, it was hypothesized that during a primary immune response generation of IgM-IC may occur, resulting in binding and activation of C1, dissociation of activated C1 by C1 inhibitor and subsequent interaction of IgM-IC bearing C1q with EC–C1qR.…”
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Ecological security driving mechanisms and optimization of zoning in Chinese urban agglomerations: A case study of the central plains urban agglomeration by Jinyuan Zhang, Xuning Qiao, Yongju Yang, Liang Liu, Yalong Li, Shengnan Zhao

“…Spatial disparities in ecological security were relatively small, and counties with lower ecological security levels tended to show greater clustering; (2) The explanatory power of the driving factors is ranked as follows: human factors > natural factors > landscape factors. Interaction detection factors exhibit varying degrees of dual-factor or nonlinear enhancement, with the combined strength of positive effects being greater than that of negative effects; (3) The spatial distribution characteristics of ecological security zones in the CPUA align with those of ecological security conditions. …”
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Empirical Analysis of the Impact of the Internet on Social Trust in Chinese Provinces during 2016-2020 by Li Zhengrong, Guo Mengyao, Wang Fang

“…Fourth, the "dual-sided" effect of online social networking, as observed in this study, is manifested in its deleterious impact on trust within established social circles while simultaneously exerting a constructive influence on trust in individuals outside one's immediate network, thereby exemplifying the role of the Internet as a double-edged sword, where its capacity to both enhance and undermine trust depends on the nature of the interaction and the context in which it occurs. This study has significant implications for the scientifically sound and rational utilization of the positive role of the Internet as well as for balancing the development of information technology with social progress. …”
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Whole-transcriptome analysis reveals the profiles and roles of coding and non-coding RNAs during hair follicle cycling in Rex rabbits by Jie Wu, Jiamin Zhai, Haofan Jia, Ifeanyi Solomon Ahamba, Xianggui Dong, Zhanjun Ren

“…Target genes of DEMs were mainly enriched in MAPK signaling pathway, Wnt signaling pathway, ECM-receptor interaction and Signaling pathways regulating pluripotency of stem cells. …”
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