A systematic review of serious games as tools for STEM education by Talia Tene, Diego Fabián Vique López, Paulina Elizabeth Valverde Aguirre, Nilo Israel Cabezas Oviedo, Cristian Vacacela Gomez, Stefano Bellucci

“…ObjectiveSerious games are increasingly recognized as innovative tools in STEM (Science, Technology, Engineering, and Mathematics) education, providing engaging and interactive learning environments that can enhance student performance, engagement, and learning outcomes. …”
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Gains and pains: a qualitative study on the implications of value-based health care for professionals by Veerle van Engen, Igna Bonfrer, Fabio Mieris, Malou Ensink, Anne Stiggelbout, Kees Ahaus, Martina Buljac-Samardzic

“…Interview questions and data analysis were guided by the Job Demands–Resources model. Results VBHC interacts with four themes perceived to affect professional’s motivation (perception of making a positive impact, enjoyability of job activities, personal development, and sense of community and support) and three themes perceived to affect job strain (workload, cognitive demands, and confidence). …”
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PENGARUH STRATEGI PROBLEM BASED LEARNING DAN MOTIVASI BERPRESTASI TERHADAP KETERAMPILAN BERPIKIR KRITIS by Supriyanto Supriyanto, Achmad Noor Fatirul, Djoko Adi Walujo

“…Kata  kunci: problem based learning, inquiry, motivasi berprestasi, berpikir kritis   ABSTRACT   The aims of this research are: 1) to find out the results of differences in students' critical thinking skills between those taught with problem based learning and inquiry strategies. 2) knowing the difference between high and low achievement motivation on students' critical thinking skills. 3) find out the difference in the interaction between problem based learning and achievement motivation on critical thinking skills. …”
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Staphylococcus aureus vesicles impair cutaneous wound healing through p38 MAPK-MerTK cleavage-mediated inhibition of macrophage efferocytosis by Jiaxin Ou, Kangxin Li, Hui Yuan, Shaohua Du, Tingting Wang, Qiannan Deng, Huimei Wu, Weiyan Zeng, Kui Cheng, Kutty Selva Nandakumar

“…Abstract Background Staphylococcus aureus, a known contributor to non-healing wounds, releases vesicles (SAVs) that influence the delicate balance of host-pathogen interactions. Efferocytosis, a process by which macrophages clear apoptotic cells, plays a key role in successful wound healing. …”
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Construction of a circRNA-miRNA-mRNA Regulatory Network for Coronary Artery Disease by Bioinformatics Analysis by Zebo Zhang, Haiyan Qian, Li Wang, Zhenbo Tao, Keai Cheng, Kaiyue Wang, Yanqing Xie, Lina Zhang

“…Bioinformatics analysis was performed to construct a ceRNA regulatory network, from which the hub genes involved were identified through protein-protein interaction (PPI) networks leading to the identification of the circRNA-miRNA-hub gene subnetwork. …”
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An Unusual Case of Ototoxicity with Use of Oral Vancomycin by Umut Gomceli, Srija Vangala, Cosmina Zeana, Paul J. Kelly, Manisha Singh

“…Additionally, the only other medication prescribed to the patient at the time of vancomycin administration was metformin at a dose of 500 mg po bid which has no known idiosyncratic interactions potentiating adverse side effects to vancomycin. …”
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A bacterial membrane-disrupting protein stimulates animal metamorphosis by Kyle E. Malter, Tiffany L. Dunbar, Carl Westin, Emily Darin, Josefa Rivera Alfaro, Nicholas J. Shikuma

“…Although this host-microbe interaction is critical to establishing and maintaining marine animal populations, the functional activity of bacterial products and how they activate the host’s metamorphosis program has not yet been defined for any animal. …”
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Investigating the Pulmonary Host Response of <i>Acinetobacter baumannii</i> Infection-Associated Pneumonia by Metagenomic Next-Generation Sequencing by Mu-Jung Chou, Chih-Hung Cheng, Hui-Ching Wang, Ming-Ju Tsai, Chau-Chyun Sheu, Wei-An Chang

“…The STRING was employed for identifying protein interaction pathways related to the pulmonary host response to pneumonia caused by <i>A. baumannii</i> without antimicrobial-resistant genes. …”
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Exploring the Prognostic Role of Trop-2, CD47, and CD163 Expression Levels on Survival Outcomes in Patients with Triple-Negative Breast Cancer by Ramazan Oguz Yüceer, Sedanur Aydın, Iclal Gelir, Tulay Koc, Ersin Tuncer, Mahmut Ucar

“…<b>Background</b>: This study evaluated the prognostic impact of Trop-2, CD47, and CD163 expression on clinical outcomes in triple-negative breast cancer (TNBC) and investigated their interactions with tumor progression. <b>Methods</b>: A retrospective cohort of 92 patients with TNBC was analyzed. …”
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Protective and Ameliorative Effects of Hydroethanolic Extract of Piper nigrum (L.) Stem against Antiretroviral Therapy-Induced Hepatotoxicity and Dyslipidemia in Wistar Rats by Doreen Enyang, Mubo A. Sonibare, Armelle D. Tchamgoue, Lauve R. Y. Tchokouaha, Fanta S. Yadang, Gael N. Nfor, Christelle W. Kom, Patrick D. H. Betote, Cedric F. Tchinda, Steveng S. K. Tiogo, Gabriel A. Agbor

“…Further studies are necessary to understand the pharmacokinetic interactions between ART and PNS.…”
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Physiological responses to water deficiency in bread wheat (Triticum aestivum L.) lines with genetically different leaf pubescence by S. V. Osipova, A. V. Rudikovskii, A. V. Permyakov, E. G. Rudikovskaya, M. D. Permyakova, V. V. Verkhoturov, T. A. Pshenichnikova

“…Presumably, the revealed effects are associated with violations of cross-regulatory interactions between the proteins of the trichome formation network and transcription factors that regulate plant growth and stress response.…”
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The Association of moisture intake and constipation among us adults: evidence from NHANES 2005–2010 by Deng-Chao Wang, Xue-Feng Peng, Wen-Xing Chen, Miao Yu

“…Depression may modulate the relationship between moisture and constipation (interaction effect P = 0.014). Conclusion The findings of this study indicate that appropriate dietary moisture intake is significantly associated with a lower risk of constipation, demonstrating a dose-response relationship. …”
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Cohort profile: Anhui Maternal–Child Health Study in China by Yunxia Cao, Ruoling Chen, Weiju Zhou, Xiaofeng Xu, Xiaoqing Peng, Jiaqian Yin, Chunmei Liang, Ranjit Khutan, Fang-Biao Tao

“…Among the 1057 couples with successful ART who were followed up for delivering babies, 576 had their children examined at age 30–42 days, 459 at 6 months and 375 at 12 months.Future plans The AMCHS will identify comprehensive risk factors for poor ART outcomes and explore potential interaction effects of multiple factors including sociopsychological aspects of environmental exposure, dietary intake and genetics on maternal and child health.…”
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Compensatory effects conceal large uncertainties in the modelled processes behind the relationship between the El Niño–Southern Oscillation (ENSO) and CO₂ by I. Dunkl, I. Dunkl, A. Bastos, T. Ilyina, T. Ilyina, T. Ilyina

“…These pathways result from the configuration of three interacting processes that contribute to the overall ENSO–<span class="inline-formula">CO₂</span> relationship: ENSO strength, ENSO-induced climate anomalies, and the sensitivity of NBP to climate. …”
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Using a co-design approach to develop a Preventative Online Mental Health Program for Youth (POMHPY): a quality improvement project by Elnaz Moghimi, Kimberly Belfry, Sarah Farr, Shavon Stafford, Arina Bogdan, Megan Brush, Christopher Canning, Soyeon Kim

“…The resulting 6-week program, led by youth facilitators, will focus on teaching mental, social, and physical wellness strategies and skills through various evidence-based, interactive activities.…”
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Efficacy of combined colorectal cancer treatment in senile patients by P. V. Tsarkov, D. R. Markaryan, V. M. Nekoval

“…Due to complex drugto-drug interactions specificity of metabolism and biological tumor properties, cross-reactions of concomitant diseases in senile patients each step of combined treatment should be discussed at multidisciplinary consultation.…”
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Pulmonary and systemic immune alterations in rats exposed to airborne lunar dust by Brian E. Crucian, Heather Quiriarte, Chiu-wing Lam, Mayra Nelman, Audrie A. Colorado, Douglass M. Diak, John T. James

“…Assays included leukocyte distribution by multicolor flow cytometry and electron/fluorescent microscopy to visualize cell–particulate interactions and lavage/plasma cytokine concentration. …”
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Knowledge Management System Berbasis Web tentang Budidaya Hidroponik untuk Mendukung Smart Society by Ariq Cahya Wardhana, Yani Nurhadryani, Sri Wahjuni

“…Knowledge map is used for codification of knowledge that produces 34 explicit knowledge in the form of interactive media in the form of videos and documents that can be used by user. …”
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Characteristics Associated with Successful Residency Match in General Surgery by Reagan A. Collins, BA, Kaitlyn Nimmer, BA, Salma A. Sheriff, BS, Tania K. Arora, MD, Anai N. Kothari, MD, MS, Carrie Cunningham, MD, MPH, Callisia N. Clarke, MD, MS

“…Program directors heavily factored step 1 and step 2 scores, letters of recommendation, interactions with faculty and trainees, and interpersonal skills when interviewing and ranking applicants. …”
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Enhancing Pan evaporation predictions: Accuracy and uncertainty in hybrid machine learning models by Khabat Khosravi, Aitazaz A. Farooque, Amir Naghibi, Salim Heddam, Ahmad Sharafati, Javad Hatamiafkoueieh, Soroush Abolfathi

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