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6681
Immune Checkpoint Inhibitor Therapy for Bone Metastases: Specific Microenvironment and Current Situation
Published 2021-01-01“…In this review, the characteristics and interaction of bone metastases and their immune microenvironment were systematically discussed, and the relevant research progress of the immunological mechanism of tumor bone metastasis was reviewed. …”
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6682
The irrelevance of case for DP movement in English
Published 2024-12-01“…As a consequence, standard assumptions about the interaction of case assignment and movement can be questioned. …”
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6683
A Project Report on the Work Carried out on the Medical Clinic At Nyabikoni Campus Kabale University.
Published 2023“…The information contained in this report is based on the work l physically did as a project, my personal research using the many available resources and interactions l had with different experts on our faculty of engineering and technology. …”
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6684
The Potential Impacts of The East African Crude Oil Pipeline (EACOP) On Human Rights in Uganda.
Published 2023“…This paper is primarily centered on interaction between the advancement of the East African Crude Oil Pipeline (herein after the EACOP) on one hand and aspects of human rights on the other hand. …”
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6685
A Network Pharmacology-Based Approach for Exploring Key Active Compounds and Pharmacological Mechanisms of Tangshen Formula for Treatment of Diabetic Nephropathy
Published 2021-01-01“…A network pharmacology approach was firstly applied to explore multiple active compounds and multiple key pharmacological mechanisms for TSF treating DN by drug-targeted interaction databases, herb-compound-target network, protein-protein interaction network, compound-target-pathway network, and analysis methods. …”
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6686
Chemokine Profiles Are Affected in Serum of Patients with Acute Rejection of Kidney Allograft
Published 2021-01-01“…Our study of 138 patients focused on one-year monitoring of serum concentrations of 12 chemokines regulating the recruitment of different immune cells into transplanted allograft and on in vitro regulation of the same chemokines release by interactions of renal proximal epithelial cells with monocyte/macrophage cell line stimulated with TNF alpha. …”
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6687
Protocol of the Nutritional, Psychosocial, and Environmental Determinants of Neurodevelopment and Child Mental Health (COINCIDE) study [version 2; peer review: 2 approved]
Published 2024-11-01“…While previous studies have examined the independent effects of nutritional status, psychosocial adversities, and environmental pollutants on children’s outcomes, little is known about their interaction and cumulative effects. Objectives This study aims to investigate the independent, interaction, and cumulative effects of nutritional, psychosocial, and environmental factors on children’s cognitive development and mental health in urban and rural India. …”
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6688
Supramolecular Organic Framework with Multidimensional Storage Spaces for Ultrahigh-Capacity Iodine Capture from Seawater
Published 2025-01-01“…By combining the charge interaction of the amine and pyridyl groups from the compounds with the binding ability of aromatic rings, SOF-HTNI achieves impressive iodine adsorption capacities of 436.56 mg g−1 to iodide and 5.03 g g−1 to triiodide. …”
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6689
CC-96673 (BMS-986358), an affinity-tuned anti-CD47 and CD20 bispecific antibody with fully functional fc, selectively targets and depletes non-Hodgkin’s lymphoma
Published 2024-12-01“…Cluster of differentiation 47 (CD47) is a transmembrane protein highly expressed in tumor cells that interacts with signal regulatory protein alpha (SIRPα) and triggers a “don’t eat me” signal to the macrophage, inhibiting phagocytosis and enabling tumor escape from immunosurveillance. …”
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6690
Effect of Acetyl tributyl citrate on bone metabolism based on network toxicology and molecular docking technology
Published 2025-01-01“…Additionally, molecular docking simulations performed with AutoDock software confirmed the robust binding interactions between ATBC and these core targets, reinforcing our understanding of their interactions. …”
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6691
Exploring the multi-targeted mechanism of Saikosaponin A in prostate cancer treatment: a network pharmacology and molecular docking approach
Published 2025-02-01“…However, the mechanism underlying the effects of SSA in prostate cancer treatment remains elusive.MethodsIn this study, a network pharmacology approach was applied to identify relevant targets from drug- and disease-related databases, and intersections were analyzed using Venny2.1 to construct a Protein-Protein interaction (PPI) interaction network. Next, Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses were performed to elucidate associated biological functions and signaling pathways. …”
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6692
Identification of Critical Signature in Post‐Traumatic Stress Disorder Using Bioinformatics Analysis and in Vitro Analyses
Published 2025-01-01“…Notably enriched pathways included neuroactive ligand‐receptor interaction, mechanistic target of rapamycin (mTOR) signaling pathway, nicotine addiction, and dopaminergic synapse. …”
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6693
Evidence in Practice of Tissue Healing with Latex Biomembrane: Integrative Review
Published 2019-01-01“…Wound healing is a perfectly coordinated cascade of cellular, molecular, and biochemical events which interact in tissue reconstitution. Chronic diseases such as pressure ulcers (PU) and diabetes mellitus (DM) are considered risk factors for wound healing. …”
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6694
Impact of wave–current coupling on the bottom boundary layer in Bohai Bay
Published 2025-01-01“…Our results highlight the profound impacts of wave–current interactions on the formation and disappearance of the FML within the BBL in silty, shallow marine environments. …”
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6695
Globular-shaped Aβ oligomers have diverse mechanisms for promoting Aβ aggregations with the facilitation of fibril elongation
Published 2025-02-01“…We also showed that the molecular interaction of gAβO was altered by the presence and amount of MF seeds in the reaction buffers, indicating that complex interactions would exist among different Aβ species. …”
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6696
Exploring avocado consumption and health: a scoping review and evidence map
Published 2025-02-01“…The results have been made public and freely available, and a visual, interactive map was created to aid in science translation. …”
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6697
IGF2BP2 Shapes the Tumor Microenvironment by Regulating Monocyte and Macrophage Recruitment in Bladder Cancer
Published 2024-12-01“…NicheNet and SCENIC analyses were used to predict cell–cell interactions and transcriptional regulators, respectively. …”
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6698
Transcriptomic and proteomic analysis of the jejunum revealed the effects and mechanism of protocatechuic acid on alleviating Salmonella typhimurium infection in chickens
Published 2025-01-01“…Mechanistically, the transcriptomic results showed that dietary protocatechuic acid inhibited acute inflammatory response and activated the signaling pathways of cytokine-cytokine receptor interaction, complement and coagulation cascades. Results of proteomic showed that protocatechuic acid inhibited the positive regulation of dendritic cell cytokine production and I-κB kinase/NF-κB signaling, as well as cytokine-cytokine receptor interaction and MAPK signaling pathways, and activated the mTOR signaling pathways. …”
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6699
Immune microenvironment spatial landscapes of tertiary lymphoid structures in gastric cancer
Published 2025-02-01“…Single-cell RNA sequencing revealed strong intercellular interactions in the presence of TLS within the microenvironment. …”
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6700
Adhesion-induced MoS2 layer transfer via in-situ TEM-nanoindentation: Effects of curvature and substrate mediated residual stress
Published 2025-01-01“…To address this, we conducted a comprehensive study investigating the interaction forces originating from the bonding between atoms that govern the adhesion of ultra-thin 2D MoS2. …”
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