Metabonomic-Transcriptome Integration Analysis on Osteoarthritis and Rheumatoid Arthritis by Ningyang Gao, Li Ding, Jian Pang, Yuxin Zheng, Yuelong Cao, Hongsheng Zhan, Yinyu Shi

“…TRAF3-acetoacetate interaction may be involved in regulating inflammation in OA and RA by the NF-kappa B and IL-17 pathway.…”
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Exploring Zinc C295 as a Dual HIV-1 Integrase Inhibitor: From Strand Transfer to 3′-Processing Suppression by Sharif Karim Sayyed, Marzuqa Quraishi, D. S. Prabakaran, Balaji Chandrasekaran, Thiyagarajan Ramesh, Satish Kumar Rajasekharan, Chaitany Jayprakash Raorane, Tareeka Sonawane, Vinothkannan Ravichandran

“…Molecular docking and molecular dynamics simulations were employed to analyse Zinc C295’s interactions with the 3′P allosteric site of HIV-1 integrase. …”
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The regulation of tobacco growth under preceding crop planting: insights from soil quality, microbial communities, and metabolic profiling by Peiyan Zhao, Houfa Zhou, Xiaolin Liao, Leifeng Zhao, Yuanxian Zheng, Tiane Xiong, Gaorun Zhang, Sirong Jiang, Jiming Wang, Yuansheng He, Jiangtao Li, Jieying Zhu, Yongjun Zhang, Yanrun Li, Fuzhao Nian, Di Liu

“…These findings offer new insights into the potential interactions between rhizosphere metabolites and microbial communities and strategies of comprehensively regulating tobacco growth.…”
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Meso Hybridized Silk Fibroin Watchband for Wearable Biopotential Sensing and AI Gesture Signaling by Xiao Wang, Changsheng Lu, Zerong Jiang, Guangwei Shao, Jingzhe Cao, Xiang Yang Liu

“…These results have significant implications for human‐machine interaction, including applications in underwater robot control, drone operation, and autonomous vehicle control.…”
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Monodispersed Iron Selenide Nanoparticles United with Carbon Nanotubes for Highly Reversible Zinc–Air Batteries by Hua Zhang, Tong Zeng, Jiale Ma, Yue Jiang, Yang Huang, Yuxin Cheng, Haifeng Ye, Cuiyun Zeng, Chenghui Zeng, Minshen Zhu, Shuiliang Chen

“…Monodispersed nanoparticles on a conductive framework through strong metal–support interactions are known to show excellent catalytic performance. …”
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Correlation Between Prognostic Nutritional Index and Heart Failure in Adults with Diabetes in the United States: Study Results from NHANES (1999–2016) by Qiyuan Bai, Hao Chen, Zhen Gao, Xuhua Li, Jiapeng Li, Shidong Liu, Bing Song, Cuntao Yu

“…Participants in the highest PNI quartile (Q4) had a 63% reduced risk of heart failure compared to those in the lowest quartile (Q1). Tests for interactions did not reveal any statistically significant differences among these stratified subgroups (p for interaction > 0.05). …”
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Cell signaling communication within papillary craniopharyngioma revealed by an integrated analysis of single-cell RNA sequencing and bulk RNA sequencing by Xiaoyue Zhu, Yanfei Jia, Zicheng Zhao, Xiaoyu Zhang, Yunlong Zhao, Songbai Gui, Xiu-An Yang

“…The most relevant ligand and receptor interactions among different cells were calculated using the CellChat package in R software. …”
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Metformin blocks BIK1-mediated CPK28 phosphorylation and enhances plant immunity by Yazhou Bao, Qian Zhang, Hai Zhu, Yong Pei, Yaning Zhao, Yixin Li, Peiyun Ji, Dandan Du, Hao Peng, Guangyuan Xu, Xiaodan Wang, Zhiyuan Yin, Gan Ai, Xiangxiu Liang, Daolong Dou

“…Additionally, surface plasmon resonance (SPR) and microscale thermophoresis (MST) techniques were employed to identify MET targets. Protein-protein interactions were analyzed using a luciferase complementation assay and a co-immunoprecipitation assay. …”
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Black Hole Accretion and Spin-up through Stellar Collisions in Dense Star Clusters by Fulya Kıroğlu, Kyle Kremer, Sylvia Biscoveanu, Elena González Prieto, Frederic A. Rasio

“…Dynamical interactions in dense star clusters could significantly influence the properties of black holes, leaving imprints on their gravitational-wave signatures. …”
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Flexibility in PAM recognition expands DNA targeting in xCas9 by Kazi A Hossain, Lukasz Nierzwicki, Modesto Orozco, Jacek Czub, Giulia Palermo

“…We demonstrate that while wild-type Cas9 enforces stringent guanine selection through the rigidity of its interacting arginine dyad, xCas9 introduces flexibility in R1335, enabling selective recognition of specific PAM sequences. …”
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Numerical Investigation of an Axisymmetric Model Scramjet Assisted with Cavity of Different Aft Wall Angles by Guangwei Ma, Mingbo Sun, Guoyan Zhao, Pei Liu, Tao Tang, Li Fan, Hongbo Wang

“…In the reacting flow field, the volume of the cavity full of hot products and free radicals increases while the interaction between the cavity and main flow decreases with the increase of the aft wall angle. …”
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Graph Convolutional Networks for multi-modal robotic martial arts leg pose recognition by Shun Yao, Yihan Ping, Xiaoyu Yue, Xiaoyu Yue, He Chen, He Chen

“…IntroductionAccurate recognition of martial arts leg poses is essential for applications in sports analytics, rehabilitation, and human-computer interaction. Traditional pose recognition models, relying on sequential or convolutional approaches, often struggle to capture the complex spatial-temporal dependencies inherent in martial arts movements. …”
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Application of the Box–Behnken Design in the Development of Amorphous PVP K30–Phosphatidylcholine Dispersions for the Co-Delivery of Curcumin and Hesperetin Prepared by Hot-Melt Ex... by Kamil Wdowiak, Lidia Tajber, Andrzej Miklaszewski, Judyta Cielecka-Piontek

“…Fourier-transform infrared spectroscopy (FTIR) was employed to assess the intermolecular interactions. The apparent solubility and dissolution profiles of the systems were studied in phosphate buffer at pH 6.8. …”
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Immunological Dynamics Associated with Direct-Acting Antiviral Therapies in Naive and Experimented HCV Chronic-Infected Patients by Grenda Leite Pereira, Andréa Monteiro Tarragô, Walter Luiz Lima Neves, Pedro Vieira da Silva Neto, Priscila Sarmento de Souza, Juliana dos Santos Affonso, Keyla Santos de Sousa, Jéssica Albuquerque da Silva, Allyson Guimarães Costa, Flamir da Silva Victoria, Marilu Barbieri Victoria, Adriana Malheiro

“…On the other hand, experienced patients demonstrated a poor interaction between cytokines, chemokines, and cells with a strong correlation between IL-10, IL-6, CXCL-10, and CD8+ besides the interactions between IFN-γ and IL-4. …”
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The effect of salicylic and jasmonic acids on the activity of <i>SnAGO</i> genes in the fungus <i>Stagonospora nodorum</i> Berk. in <i>in vitro</i> culture and during infection o... by M. Yu. Shein, G. F. Burkhanova, I. V. Maksimov

“…Thus, our data prove that the SnAGO genes of the fungus S. nodorum effectively interact with the host defense system in direct proportion to the degree of resistance of the latter to the pathogen. …”
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Raman spectroscopy study of the role of dispersion and interfaces in the improvement of the mechanical properties of epoxy-TiO2 composites by María Fernández-Álvarez, Alberto Moure, Luis Angulo Delgado, Julián J. Reinosa, José F. Fernández

“…The final properties and durability of advanced epoxy-based composites reinforced with ceramic particles depend on both the particle dispersion and the particle-matrix interaction. The main objective of this work is to understand the role of TiO2 particle dispersion in an epoxy matrix by high-resolution confocal Raman spectroscopy, evaluating the nature of their interaction and the crosslinking state of the polymeric matrix. …”
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Novel Speech-Based Emotion Climate Recognition in Peers&#x2019; Conversations Incorporating Affect Dynamics and Temporal Convolutional Neural Networks by Ghada Alhussein, Mohanad Alkhodari, Ahsan H. Khandoker, Leontios J. Hadjileontiadis

“…The latter, apart from facial and gestural expressions, it is also naturally conveyed via peers&#x2019; speech, contributing to the establishment of a dynamic emotion climate (EC) during their conversational interaction. Recognition of EC could provide an additional source in understating peers&#x2019; social interaction and behavior on top of peers&#x2019; actual conversational content.We propose a novel approach for speech-based EC recognition, termed AffECt, which combines peers&#x2019; complex affect dynamics (AD) with deep features extracted from speech signals using Temporal Convolutional Neural Networks (TCNNs). …”
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CENPN contributes to pancreatic carcinoma progression through the MDM2-mediated p53 signaling pathway by Ming Xu, Jie Tang, Qiong Sun, Jing Meng, Guoyu Chen, Yunli Chang, Yao Yao, Jieru Ji, Hao Luo, Lingling Chen, Minxue Lu, Weiwei Shi

“…Additionally, CENPN interacted with MDM2, promoting PAAD progression by targeting the p53 signaling pathway. …”
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Redefining NSP12 activity in SARS-CoV-2 and its regulation by NSP8 and NSP7 by Deepa Singh, Tushar Kushwaha, Rajkumar Kulandaisamy, Vikas Kumar, Kamal Baswal, Saras H. Tiwari, Arkadyuti Ghorai, Manoj Kumar, Saroj Kumar, Soumya De, Aparoy Polamarasetty, Deepak Sehgal, Madhumohan R. Katika, Suresh Gadde, Marceline Côté, Sarala R. Kayampeta, Mohan Babu Appaiahgari, Krishna K. Inampudi

“…These findings have implications for novel drug development, and compounds inhibiting NSP7 or NSP8 interactions with NSP12 can be lethal to coronavirus replication.…”
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Synthesis and Spatial Structure of 3-Phenylacrylic Acid Octahydroquinolizin-1-Ylmethyl Ester and 2-(Octahydroquinolizin-1-Ylmethyl)Isoindole-1,3-Dione by Zh.S. Nurmaganbetov, O.A. Nurkenov, S.D. Fazylov, D.M. Turdybekov, Ye.V. Minayeva, G. Khabdolda, A.M. Ibraybekova, Zh.S. Tilla, K.M. Turdybekov

“…It was demonstrated that the interaction of chlorolupinine with 2-K-isoindole-1,3-dione under Gabriel reaction conditions resulted in the formation of 2-(octahydroquinolizin-1-ylmethyl)isoindole-1,3-dione. …”
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