The role of SASP in ischemic stroke: a deep dive into cellular mechanisms by Dong Xie, Yang Liu, Fang-Biao Xu, Jin-Sheng Zhang

“…RT-qPCR demonstrated a marked elevation in Lcp1 mRNA and a pronounced reduction in Ccl3 in the MCAO group relative to the Sham group.ConclusionThe Ccl3 gene in basophils and its immune cell interaction is a linchpin in the IS immune microenvironment. …”
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Inheritance of scald resistance in four barley landraces by G. S. Konovalova, E. E. Radchenko

“…The pathogen is characterized by the differential interaction with the host plant genotypes. Therefore, the most rational plant breeding strategy should envisage broadening of genetic diversity of cultivated varieties. …”
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PLATFORM CAPITALISM AS THE SOURCE OF DIGITAL RENTIER’S SUPERPROFIT by I. M. Stepnov, J. A. Kovalchuk

“…The authors believe that the «digital economy» concept does not reflect the essence of the processes in terms of the theory of capitalist development, economic interaction, the dilemma solution of coordination and competition in the economy. …”
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Oral Complications in Hematopoietic Stem Cell Recipients: The Role of Inflammation by T. M. Haverman, J. E. Raber-Durlacher, W. M. H. Rademacher, S. Vokurka, J. B. Epstein, C. Huisman, M. D. Hazenberg, J. J. de Soet, J. de Lange, F. R. Rozema

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Research and Discussion on the Relationships between Noise-Induced Hearing Loss and ATP2B2 Gene Polymorphism by Suhao Zhang, Enmin Ding, Haoyang Yin, Hengdong Zhang, Baoli Zhu

“…Multifactor dimensionality reduction analysis revealed that the interaction between rs14154 and rs3209637 is linked to increased NIHL risk, and for the interaction among rs14154, smoking and drinking had the same function (OR=1.54 and 1.77, 95%CI=1.15–2.07, 1.33–2.37, and P=0.0037 and P<0.0001, respectively). …”
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A Wavelet-Based Correlation Analysis Framework to Study Cerebromuscular Activity in Essential Tremor by Yifan Zhao, Ramon C. Laguna, Yitian Zhao, Jimmy Jiang Liu, Xiongxiong He, John Yianni, Ptolemaios G. Sarrigiannis

“…This paper proposes a novel framework to address this challenge, including an estimation of the interaction strength using wavelet cross-spectrum and phase lag index while demonstrating the statistical significance of the findings. …”
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Protease shaving of Mycobacterium tuberculosis facilitates vaccine antigen discovery and delivery of novel cargoes to the Mtb surface by Bianca A. Lepe, Christine R. Zheng, Owen K. Leddy, Benjamin L. Allsup, Sydney L. Solomon, Bryan D. Bryson

“…The bacterial surface is a critical interface that shapes host-pathogen interactions. Several knowledge gaps persist in our understanding of Mycobacterium tuberculosis (Mtb)-host interactions that may be addressed by an improved understanding of the Mtb surface proteome, including the identification of novel vaccine targets as well as developing new approaches to interrogate host-pathogen interactions. …”
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Lessons learnt from horse-related human fatalities: Accident analysis using HFACS-Equestrianism by Meredith Chapman, Kate Fenner, Matthew J.W. Thomas

“…Equestrianism has an opportunity to learn lessons relating to safer human-horse interactions from those who no longer have a voice, by drawing data from the investigation of horse-related human fatalities and participating in accident analysis. …”
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REVIEW ON PROTEIN FOOTPRINTING AS A TOOL IN STRUCTURAL BIOLOGY by Oluwatosin Ogundairo, Oluwatoyin Ayo-Farai, Chinedu Paschal Maduka, Chiamaka Chinaemelum Okongwu, Abdulraheem Olaide Babarinde, Olamide Sodamade

“…The study elucidates the underlying principles of these methods, discussing the mechanisms by which protein-footprinting agents interact with amino acid residues and elucidate structural details. …”
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Species-specific influences of competition and tree size on drought sensitivity and resistance for three planted conifers in northern China by Rui Deng, Jinglei Liao, Tim Rademacher, Zhongqi Xu, Mingchao Du, Jianwei Zheng, Lihua Fu, Xianliang Zhang

“…We used tree-ring and forest inventory data from different density stands to investigate how competition, tree diameter at breast height (DBH), tree age, and their interactions influence drought sensitivity and resistance for three widely-distributed and planted conifer species (Larix principis-rupprechtii, Picea meyeri, and Pinus sylvestris var. mongolica). …”
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Care, conflict, and coexistence: Human–wildlife relations in community forests by Madison Stevens, Shalini Rawat, Terre Satterfield

“…Yet, focusing on conflict alone may obscure the complex drivers of positive and negative interactions between people and wildlife coinhabiting the same geographies. …”
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Novel palm peat lignocellulosic adsorbent derived from agricultural residues for efficient methylene blue dye removal from textile wastewater by Mohamed Mohamed Gaber, Hassan Shokry, Ahmed H. Hassanin, Said Awad, Mahmoud Samy, Marwa Elkady

“…Adsorption occurs via π-π stacking, hydrogen bonding, hydrophobic-hydrophobic interactions, and electrostatic interaction with the process being endothermic and following the Langmuir isotherm model and pseudo-second-order kinetic model. …”
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Mechanistic insights into epithelial-mesenchymal transition mediated cisplatin resistance in ovarian cancer by Taha Umair Wani, Hyun-Yi Kim, Geum-Hwa Lee, Young Je Lim, Han-Jung Chae, Ji-Ye Kim, Hyonok Yoon

“…This was further confirmed by the protein-protein interaction (PPI) analysis where we identified that the core ECM components e.g., collagen, fibronectin, metalloproteases and integrins possessed most interactions. …”
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MatE transporter affects methane metabolism in Methermicoccus shengliensis and is modulated by methoxylated aromatic compounds by Huan Leng, Dong Wang, Qing Yang, Shuxin Wang, Leizhou Guo, Pengyan Zhao, Yi Chen, Lirong Dai, Guihong Cha, Liping Bai, Frank Delvigne

“…To address this knowledge gap, we employed bacterial two-hybrid and structural model assays to investigate the interaction between Tlp and MatE. Our results revealed that Tlp senses 2-methoxybenzoate and interacts with MatE to facilitate substrate transport. …”
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Contrasting Seasonal Distribution Patterns of Two Boreal Aerial Hawking Bat Species in Finland by Piia Lundberg, Miika Kotila, Katarina Meramo, Kati M. Suominen, Miina Suutari, Tia‐Marie Pietikäinen, Ville Vasko, Thomas M. Lilley

“…ABSTRACT Climate change poses significant consequences for temperate bat species, potentially altering their distribution ranges and generating novel interactions among species sharing similar ecological niches. …”
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Association between ТР53, MDM2 and NQO1 gene polymorphisms and viral load among women with human papillomavirus by A.H. AlBosale, E. V. Mashkina

“…Quantitative analysis of HPV DNA was performed by AmpliSens® HPV HCR screen-titer-FRT test system. Gene-gene interactions were analyzed using the multifactor dimensionality reduction (MDR) method. …”
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Non-Steroidal Anti-Inflammatory Drugs Are Inhibitors of the Intestinal Proton-Coupled Amino Acid Transporter (PAT1): Ibuprofen and Diclofenac Are Non-Translocated Inhibitors by Carsten Uhd Nielsen, Sebastian Jakobsen, Maria L. Pedersen

“…In the present work, we investigate if non-steroidal anti-inflammatory drug substances (NSAIDs) interact with substrate transport via human (h)PAT1. …”
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Competitive displacement of lipoprotein lipase from heparan sulfate is orchestrated by a disordered acidic cluster in GPIHBP1 by Anamika Biswas, Samina Arshid, Kristian Kølby Kristensen, Thomas J.D. Jørgensen, Michael Ploug

“…The trans-endothelial transport of LPL depends on ionic interactions with GPIHBP1’s intrinsically disordered N-terminal tail, which harbors two acidic clusters at positions 5–12 and 19–30. …”
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Effects of socioeconomic and human-modified landscape variables on medicinal species richness at a macroscale: the case of the Caatinga, Brazil by Aníbal Silva Cantalice, Thiago Gonçalves-Souza, Ulysses Paulino Albuquerque

“…However, it remains largely unknown whether these same factors can predict knowledge of useful species at broader scales and whether their interaction might create scenarios that enhance knowledge of medicinal species. …”
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Biology, genetics, and ecology of the cosmopolitan ectomycorrhizal ascomycete Cenococcum geophilum by Huayong Wang, Annegret Kohler, Francis M. Martin, Francis M. Martin

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