AI Interventions to Alleviate Healthcare Shortages and Enhance Work Conditions in Critical Care: Qualitative Analysis by Nadine Bienefeld, Emanuela Keller, Gudela Grote

“…ObjectiveThis research investigates the efficacy of AI in alleviating stress and enriching work conditions, using intensive care units (ICUs) as a case study. Through a sociotechnical system lens, we delineate how AI systems, tasks, and responsibilities of ICU nurses and physicians can be co-designed to foster motivating, resilient, and health-promoting work. …”
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Inter-rater reliability and prognostic value of baseline Radiographic Assessment of Lung Edema (RALE) scores in observational cohort studies of inpatients with COVID-19 by Andrew I Kim, William Bain, Alison Morris, Barbara Methe, Bryan J McVerry, Georgios D Kitsios, Daniel Kotok, Janet S Lee, Nameer Al-Yousif, Christine E Girard, Jana J Jacobs, Konstantin Golubykh, Hafiz Qurashi, Michael Lu, Saketram Komanduri, Anatoliy Korzhuk, Halimat O Lawal, Nicholas Abourizk, Caitlin Schaefer, Kevin J Mitchell, Catherine M Dietz, Ellen K Hughes, Clara S Brandt, Georgia M Fitzgerald, Robin Joyce, Asmaa S Chaudhry, Jose D Rivera, Shruti Shettigar, Allen Lavina, Samantha R Gillenwater, Anas Hadeh, Faraaz A Shah, Matthew Bittner, Niall Prendergast, John Evankovich, Navitha Ramesh, Cathy Kessinger

“…Objectives To reliably quantify the radiographic severity of COVID-19 pneumonia with the Radiographic Assessment of Lung Edema (RALE) score on clinical chest X-rays among inpatients and examine the prognostic value of baseline RALE scores on COVID-19 clinical outcomes.Setting Hospitalised patients with COVID-19 in dedicated wards and intensive care units from two different hospital systems.Participants 425 patients with COVID-19 in a discovery data set and 415 patients in a validation data set.Primary and secondary outcomes We measured inter-rater reliability for RALE score annotations by different reviewers and examined for associations of consensus RALE scores with the level of respiratory support, demographics, physiologic variables, applied therapies, plasma host–response biomarkers, SARS-CoV-2 RNA load and clinical outcomes.Results Inter-rater agreement for RALE scores improved from fair to excellent following reviewer training and feedback (intraclass correlation coefficient of 0.85 vs 0.93, respectively). …”
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Etiology of Hospital-Acquired Pneumonia (HAP) and Ventilator-Associated Pneumonia (VAP) in Tertiary-Care Hospitals in Thailand: A Multicenter, Retrospective Cohort Study by Rongrungruang Y, Plongla R, Pleumkanitkul S, Hantrakun V, Khawcharoenporn T

“…After diagnosis of NP, 19 patients were transferred to intensive care units with median length of stays of 11 days (IQR 3– 24 days). …”
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The Mechanical Power in Patients with Acute Respiratory Distress Syndrome Undergoing Prone Positioning Can Predict Mortality by Ko-Wei Chang, Shaw-Woei Leu, Han-Chung Hu, Ming-Cheng Chan, Shinn-Jye Liang, Kuang-Yao Yang, Li-Chung Chiu, Wen-Feng Fang, Chau-Chyun Sheu, Ying-Chun Chien, Chung-Kan Peng, Ching-Tzu Huang, Kuo-Chin Kao

“…<b>Methods:</b> This multicenter retrospective study included data on all patients admitted to the intensive care units of eight referral hospitals in Taiwan from October 2015 to March 2016, and in Chang Gung Memorial Hospital Linkou branch from January 2017 to October 2023. …”
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Point prevalence survey of antibiotic use in Mexican secondary care hospitals. by Federico A Zumaya-Estrada, Celia M Alpuche-Aranda, Hilda Ivonne Huerta Icelo, Felipe D Neri-Estrada, Verónica M Calixto Silva, Haydee E Quiroz Escoriza, Jesus Ulises Garza-Ramos, Pedro J Saturno-Hernandez

“…We collected data from clinical records of all patients with active antibiotic prescriptions (APs) across the medical, surgical, and mixed (MIX) wards, and intensive care units (ICUs). Descriptive statistics were computed to analyze the PPSs data using Stata.…”
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The Utility of Neutrophil CD64 and Presepsin as Diagnostic, Prognostic, and Monitoring Biomarkers in Neonatal Sepsis by Heba E. Hashem, Rania M. Abdel Halim, Sherin A. El Masry, Amira M. Mokhtar, Noureldin M. Abdelaal

“…To evaluate the diagnostic, prognostic, and monitoring performance of both neutrophil CD64 (nCD64) and presepsin as sepsis biomarkers compared to each other and to the conventional laboratory sepsis parameters aiming to decide which is the best fitting for routine daily use in neonatal intensive care units (NICUs). Methods. 235 neonates were enrolled from three Egyptian neonatal ICUs, during the period from November 2015 till March 2018; they were classified into two main groups: the control group (n = 102) and the sepsis group (n = 133). …”
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Differential impact of TyG and TyG-BMI indices on short- and long-term mortality in critically ill ischemic stroke patients by Yufan Pu, Na Xing, Ying Wang, Huihuang Wang, Jiang Xu, Xuejing Li

“…Abstract Background Ischemic stroke is a major contributor to global morbidity and mortality, particularly in critically ill patients in intensive care units (ICUs). While advances in stroke management have improved outcomes, predicting mortality remains challenging due to the involvement of complex metabolic and cardiovascular factors. …”
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CHARACTERISTICS OF CYTOPROTECTIVE EFFECT ON THE GASTRIC MUCOSA OF CRYOPRESERVED PLACENTA EXTRACT UNDER WATER-IMMOBILIZATION STRESS by Illia Koshurba, Fedir Hladkykh, Mykola Chyzh

“…Among patients in intensive care units, the incidence of stress ulcers is 5.0%, and in 30.0-50.0% of cases stress ulcers are complicated by bleeding and perforation. …”
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A Predictive Model for Pulmonary Aspergillosis in ICU Patients: A Multicenter Retrospective Cohort Study by Li Y, Ren X, Wang Q, Shen S, Li Y, Qian X, Tang Y, Jia J, Zhang H, Ding J, Song Y, Zhang S, Wang S, Xu Y, Jiang Y, He X, Dai M, Zhong L, Xiong Y, Pan Y, Wang M, Shao H, Cai H, Huang L, Wang H

“…This study aimed to develop a risk prediction model for IPA by integrating clinical and microbiological characteristics.Methods: This retrospective study was conducted in adult intensive care units (ICUs) of 17 medical centers in China. …”
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Association of the blood urea nitrogen to serum albumin ratio and all-cause mortality in critical ill acute ischemic stroke patients: a retrospective cohort study of MIMIC-IV datab... by Yongwei Huang, Zongping Li, Jianjun Wang, Jianjun Wang, Decai Wang, Decai Wang, Xiaoshuang Yin

“…PurposeWe aim to ascertain the extent to which the blood urea nitrogen (BUN) to serum albumin (ALB) ratio (BAR) could be implemented to anticipate the short- and long-term prognosis of acute ischemic stroke (AIS) patients in intensive care units (ICUs).MethodsThe data was derived from the Marketplace for Intensive Care Medical Information-IV (MIMIC-IV v3.0) database, primarily pertaining to AIS patients as categorized by the International Classification of Diseases (ICD)-9 and ICD-10. …”
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Comments on: “Early High-Titer Convalescent Plasma Therapy in Patients with Moderate and Severe COVID-19” [Transfusion and Apheresis Science 61 (2022) 103321] by Seyed Reza Hosseiniara

“…Furthermore, a recent systematic review and meta-analysis encompassing 39 studies reported an overall pooled case fatality rate of 10% among COVID-19 patients.3 Other studies have indicated in-hospital mortality rates ranging from 4.5% to 8.8% among Iranian patients,4,5 while the mortality rate in intensive care units was found to be as high as 67.6%.6 Investigations conducted in other Asian populations have demonstrated mortality rates of 5-7.2% for patients with mild to moderate COVID-19.7,8 These findings are particularly relevant, as they suggest lower fatality rates than those observed in the study by Fazeli et al.,1 among Iranian patients treated with convalescent plasma therapy.Fazeli et al. conducted a multivariate logistic regression analysis to assess the effectiveness of high-titer convalescent plasma therapy in patients with moderate COVID-19. …”
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