Severe pregnancy-associated atypical hemolytic uremia syndrome in the context of the COVID-19 pandemic: a novel survival case report by Yan Yang, Xiao-jin Li, Hua-Yan Yuan, Jing-Jing Xiong, Peng-Fei Li, Zhen Wang

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Protocol for assessing and visualizing cell microaggregate formation in whole blood by imaging flow cytometry by Johannes Krell, Komal Kumar Javarappa, Angie Wenedy, Andrew L. Frelinger, III, Laurent Renia, Clarissa Prazeres da Costa, Martin Schlegel, Percy Knolle, Gerhard Schneider, Oliver Hayden

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Enterococcus faecium Mediastinitis Complicated by Disseminated Candida parapsilosis Infection after Congenital Heart Surgery in a 4-Week-Old Baby by Hanna Renk, Felix Neunhoeffer, Florian Hölzl, Michael Hofbeck, Matthias Kumpf

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Increased Extravascular Lung Water Reduces the Efficacy of Alveolar Recruitment Maneuver in Acute Respiratory Distress Syndrome by Alexey A. Smetkin, Vsevolod V. Kuzkov, Eugeny V. Suborov, Lars J. Bjertnaes, Mikhail Y. Kirov

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Peripherally inserted central catheters versus implanted port catheters in patients with breast cancer: a post hoc analysis of the PICCPORT randomised controlled trial by Anton Utas, Stefanie Seifert, Knut Taxbro

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Impact of acute respiratory distress syndrome on outcome in critically ill patients with liver cirrhosis by Pischtaz Adel Tariparast, Kevin Roedl, Thomas Horvatits, Andreas Drolz, Stefan Kluge, Valentin Fuhrmann

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Targeting protein kinase C-α prolongs survival and restores liver function in sepsis: Evidence from preclinical models by Ling Xiong, Dustin Beyer, Na Liu, Tina Lehmann, Sophie Neugebauer, Sascha Schaeuble, Oliver Sommerfeld, Philipp Ernst, Carl-Magnus Svensson, Sandor Nietzsche, Sebastian Scholl, Tony Bruns, Nikolaus Gaßler, Markus H. Gräler, Marc Thilo Figge, Gianni Panagiotou, Michael Bauer, Adrian T. Press

“…This suggests that targeting this protein could restore liver function without compromising the immune system, thereby decreasing sepsis mortality and supporting the recent paradigm that the liver is a hub for the host response to infection that might, in the future, result in novel host-directed therapies supporting the current state-of-the-art intensive care medicine in patients with sepsis-associated liver failure.…”
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Ursodeoxycholic acid protects against sepsis-induced acute kidney injury by activating Nrf2/HO-1 and inhibiting NF-κB pathway by Yunpeng Lou, Hongguang Shi, Ning Sha, Feifei Li, Xiaofeng Gu, Huiyan Lin

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Accuracy of Established Prognostic Staging Systems for Cardiac Transthyretin Amyloidosis in the Tafamidis Era by Maximilian Leo Müller, MD, Sebastian Spethmann, MD, Daniel Messroghli, MD, Anna Brand, MD, Isabel Mattig, MD, Katrin Hahn, MD, Ulf Landmesser, MD, Bettina Heidecker, MD

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Risk Factors of Multidrug-Resistant Bacteria in Lower Respiratory Tract Infections: A Systematic Review and Meta-Analysis by Gang Chen, Kailiang Xu, Fangyuan Sun, Yuxia Sun, Ziyuan Kong, Bangjiang Fang

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Composite Primary Outcomes Reported in Studies of Critical Care: A Scoping Review by Prashanti Marella, MD, Sansuka De Silva, Antony G. Attokaran, Kevin B. Laupland, PhD, Lars Eriksson, BA, Mahesh Ramanan, MMed

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Exploring the association between tissue sodium content, heart failure subtypes, and symptom burden: insights from magnetic resonance imaging by Djawid Hashemi, Djawid Hashemi, Djawid Hashemi, Djawid Hashemi, Karl Jakob Weiß, Karl Jakob Weiß, Karl Jakob Weiß, Patrick Doeblin, Patrick Doeblin, Patrick Doeblin, Moritz Blum, Radu Tanacli, Radu Tanacli, Radu Tanacli, Hana Camdzic, Hana Camdzic, Hans-Dirk Düngen, Hans-Dirk Düngen, Frank Edelmann, Frank Edelmann, Frank Edelmann, Titus Kuehne, Titus Kuehne, Titus Kuehne, Marcus Kelm, Marcus Kelm, Marcus Kelm, Sebastian Kelle, Sebastian Kelle, Sebastian Kelle

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Filtration flow rate at low convection volume in continuous hemodiafiltration using cytokine adsorbing hemofilter does not affect cytokine clearance in an experimental model by Mototsugu Kudo, Shinya Chihara, Hiroomi Tatsumi, Yoshiki Masuda

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Mechanical Ventilation and the Titer of Antibodies as Risk Factors for the Development of Transfusion-Related Lung Injury by A. P. J. Vlaar, M. T. Kuipers, J. J. Hofstra, E. K. Wolthuis, C. W. Wieland, J. J. T. H. Roelofs, L. Boon, M. J. Schultz, R. Lutter, N. P. Juffermans

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The Incidence of Mental Disorders Increases over Time in Patients with Cancer Pain: Data from a Retrospective Cohort Study by Michael Brinkers, Giselher Pfau, Anne-Marie Toepffer, Frank Meyer, Moritz A. Kretzschmar

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Using a clinical decision support system to reduce excess driving pressure: the ALARM trial by Ursula Burger-Klepp, Mathias Maleczek, Robin Ristl, Bettina Kroyer, Marcus Raudner, Claus G. Krenn, Roman Ullrich

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Effect of Exogenous Melatonin Administration in Critically Ill Patients on Delirium and Sleep: A Randomized Controlled Trial by Judith Bellapart, Vinesh Appadurai, Melissa Lassig-Smith, Janine Stuart, Christopher Zappala, Rob Boots

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Complications during the Management of Dislocated Tracheostomy Cannula by Kristian Krogh, Anette Marianne Fedder

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Melatonin Secretion Pattern in Critically Ill Patients: A Pilot Descriptive Study by Yuliya Boyko, René Holst, Poul Jennum, Helle Oerding, Miki Nikolic, Palle Toft

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Trainers’ Attitudes towards Cardiopulmonary Resuscitation, Current Care Guidelines, and Training by M. Mäkinen, M. Castrén, J. Nurmi, L. Niemi-Murola

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