Epigene functional diversity: isoform usage, disordered domain content, and variable binding partners by Leroy Bondhus, Aileen A. Nava, Isabelle S. Liu, Valerie A. Arboleda

“…Additionally, we assessed the specificity of their expression profiles and showed epigenes are more ubiquitously expressed consistent with their enrichment in pediatric syndromes with intellectual disability, multiorgan dysfunction, and developmental delay. …”
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Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder by Claudia Fuchs, Laura Gennaccaro, Stefania Trazzi, Stefano Bastianini, Simone Bettini, Viviana Lo Martire, Elisa Ren, Giorgio Medici, Giovanna Zoccoli, Roberto Rimondini, Elisabetta Ciani

“…CDKL5 disorder primarily affects girls and is characterized by early-onset epileptic seizures, gross motor impairment, intellectual disability, and autistic features. Although all CDKL5 female patients are heterozygous, the most valid disease-related model, the heterozygous female Cdkl5 knockout (Cdkl5 +/−) mouse, has been little characterized. …”
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Prioritization of potato genes involved in the formation of agronomically valuable traits using the SOLANUM TUBEROSUM knowledge base by P. S. Demenkov, O. V. Saik, T. V. Ivanisenko, N. A. Kolchanov, A. V. Kochetov, V. A. Ivanisenko

“…The effective use of knowledge presented in such a number of non-formalized documents in natural language requires the use of modern intellectual methods of analysis. However, in the literature, there is no evidence of a widespread use of intelligent methods for automatically extracting knowledge from scientific publications on cultures such as potatoes. …”
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Syngap1 promotes cognitive function through regulation of cortical sensorimotor dynamics by Thomas Vaissiere, Sheldon D. Michaelson, Thomas Creson, Jessie Goins, Daniel Fürth, Diana Balazsfi, Camilo Rojas, Randall Golovin, Konstantinos Meletis, Courtney A. Miller, Daniel O’Connor, Lorenzo Fontolan, Gavin Rumbaugh

“…Here, we demonstrate in mice that expression of the autism/intellectual disability gene, Syngap1, in cortical excitatory neurons is required for the formation of somatomotor networks that promote SMI-mediated perception. …”
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Causes of Pupils' Failures At Primary Leaving Examinations in Butanda Sub-County Kabale District. by Keinika, Titus

“…Parents should show an active interest in their children's education by providing them with rich instructional materials and also make the home environment conducive to learning by ensuring homework habits, parental support and guidance, and intellectual stimulation.…”
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Constructing Identities: Amos Tutuola and the Ibadan Literary Elite in the wake of Nigerian Independence by Mackenzie Finley

“…Accordingly, the historical record has less to say about his intellectual ruminations than about those of his elite contemporaries. …”
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Pre-service teachers' perceptions of physical, socioemotional and cognitive traits in gifted students: unveiling bias? by Carmen Ferrándiz, Mercedes Ferrando-Prieto, Álvaro Infantes-Paniagua, Álvaro Infantes-Paniagua, Maria Carmen Fernández Vidal, Rosa María Pons

“…This study examines Spanish pre-service teachers' stereotypical conceptions of gifted and non-gifted students focusing on physical appearance and athletic ability.MethodsFollowing a mixed methods research with between subjects design and using a convenience sampling, 455 last-year pre-service teachers enrolled during 2023–2024 in one of three university degrees or one Master's degree related to teacher training at University of Murcia were randomly assigned a vignette in order to rate the intellectual ability, motivation, prosociality, and physical characteristics of a fictitious 12-year-old student whose ability level (gifted/non-gifted) and gender (girl/boy), varied. …”
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Whole Exome Sequencing Reveals Compound Heterozygosity for Ethnically Distinct PEX7 Mutations Responsible for Rhizomelic Chondrodysplasia Punctata, Type 1 by Jessie C. Jacobsen, Emma Glamuzina, Juliet Taylor, Brendan Swan, Shona Handisides, Callum Wilson, Michael Fietz, Tessa van Dijk, Bart Appelhof, Rosamund Hill, Rosemary Marks, Donald R. Love, Stephen P. Robertson, Russell G. Snell, Klaus Lehnert

“…We describe two brothers who presented at birth with bone growth abnormalities, followed by development of increasingly severe intellectual and physical disability, growth restriction, epilepsy, and cerebellar and brain stem atrophy, but normal ocular phenotypes. …”
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Factors influencing choice of residency program among medical intern doctors and medical students: a cross-sectional survey by Ali Al Ajmi, Masoud Kashoub, Ibrahim S. Al-Busaidi, Mohammed Al Rashdi, Moza AlHussaini, Arwa Alsaidi, Mohammed Al Rawahi, Abdullah M. Al Alawi

“…Conclusion Internal medicine emerged as a popular specialty among Omani medical students and interns, driven by intellectual stimulation, job security, and work-life balance. …”
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Le sensorium synthétique : réflexion sur l’utilisation de l’expographie immersive numérique et muséale by Dominique Gélinas

“…For a long time, the museum exhibition has been understood as an intellectual process that is analogous to an illustrated text. …”
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Sleep profile in patients with septo-optic-pituitary dysplasia: protocol for a prospective cohort study by Romina Romaniello, Sabrina Signorini, Elena Ballante, Valentina Franco, Valentina De Giorgis, Ludovica Pasca, Guido Catalano, Federica Morelli, Carlo Alberto Quaranta, Helene Vitali, Francesca Dattrino, Francesca Crema, Paola Rota, Costanza Varesio

“…Introduction Children with septo-optic-pituitary dysplasia (SOD) may experience a range of visual impairments and hormonal dysfunctions beyond developmental delay/intellectual disability. The literature describes sleep fragmentation, circadian rhythm disruptions and reduced sleep efficiency. …”
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Own Experience in the Use of Artificial Intelligence Technologies in the Diagnosis of Esophageal Achalasia by O. A. Storonova, N. I. Kanevskii, A. S. Trukhmanov, V. T. Ivashkin

“…The Federal Service for Intellectual Property (Rospatent) issued a certificate of state registration of the computer program No. 2024665795 dated July 5, 2024. …”
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Development of cohort definitions and algorithms to identify patients with Lennox-Gastaut syndrome or Dravet syndrome from real-world administrative healthcare databases by Drishti Shah, Victoria Divino, Justin Chen, Arturo Benitez, Jeannine Roth, J. Scott Andrews

“…Multiple seizure types, developmental delay, and intellectual disabilities were considered by the physicians to be key diagnostic features. …”
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Regional hippocampal thinning and gyrification abnormalities and associated cognition in children with prenatal alcohol exposure by Blake A. Gimbel, Jeffrey R. Wozniak, Bryon A. Mueller, Kent A. Tuominen, Abigail M. Ernst, Mary E. Anthony, Erik de Water, the CIFASD, Donovan J. Roediger

“…The data also demonstrate that these developmental anomalies have functional consequences in terms of core memory functions as well as global intellectual functioning in children with PAE.…”
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Choosing a starting professional trajectory: job-education mismatch effect by A. D. Melnik, A. E. Sudakova, N. L. Antonova

“…This engagement increases interest in the cultivation and early recruitment of proactive students for the development of high-tech industries and intellectual services.…”
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Inventory and Conservation of Triassic Vertebrate Tracks in the Monts d’Ardèche UNESCO Global Geopark, France by Emmanuel Fara, Jean-David Moreau, Leo Szewczyk, Nicolas Klee, Georges Gand, Emmanuelle Vennin

“…This success was made possible by the intellectual, logistic and social involvement of local people throughout, by acknowledgement of these contributions, and by the capacity of all actors to collaborate efficiently with each other. …”
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Fortified Iodine Milk Improves Iodine Status and Cognitive Abilities in Schoolchildren Aged 7–9 Years Living in a Rural Mountainous Area of Morocco by Fatima Ezzahra Zahrou, Mehdi Azlaf, Imane El Menchawy, Mohamed El Mzibri, Khalid El Kari, Asmaa El Hamdouchi, Fatima-Zahra Mouzouni, Amina Barkat, Hassan Aguenaou

“…Our study aims to assess the impact of ID on the intellectual development of Moroccan schoolchildren and to evaluate the effect of consumption of fortified milk on reducing ID. …”
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Academic burnout of digital natives and social sustainability: prevalence and risk factors by Sonja Ivančević, Veljko Dmitrović, Marko Ćirović, Nataša Petrović

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Genotypic Spectrum in a Cohort of Sri Lankan Patients With Homocystinuria by Hewa Warawitage Dilanthi, Kandana Liyanage Subhashinie Jayasena, Nambage Dona Priyani Dhammika, Neluwa Liyanage Ruwan Indika, Matara Mahavidanage Nishani De Silva, Imalke Kankananarachchi, Pushpa Malkanthi Gardiye Punchihewa, Dharma Irugalbandara, Sabine Schroeder, Kosala Karunaratne, Eresha Jasinge

“…Among the 14 patients, the common clinical features were ectopia lentis (100%), intellectual disability (92%) and marfanoid features (78%) at presentation while three of them had developed osteoporosis (21%). …”
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