Inclusive digital platforms: Designing for and with users with mild intellectual disabilities or low literacy skills by Julia F.E. van Calis, Jenneken Naaldenberg, Anneke W.C. van der Cruijsen, Monique C.J. Koks-Leensen, Geraline L. Leusink, Kirsten E. Bevelander

“…In conclusion, employing a user-sensitive inclusive research approach for the re-design of a digital research platform enabled the identification of design characteristics and elements specifically important for people with MID or LL to enhance accessibility and usability. By integrating participatory methodologies and incorporating these key design elements, digital platforms can be tailored to meet the diverse needs of individuals with MID or LL facilitating greater inclusion and participation in digital research.…”
Get full text

Immunization of cattle with a Rhipicephalus microplus chitinase peptide containing predicted B-cell epitopes reduces tick biological fitness by María Martina Esperanza Perez-Soria, Daniel Gustavo López-Díaz, Rafael Jiménez-Ocampo, Gabriela Aguilar-Tipacamú, Massaro W. Ueti, Juan Mosqueda, Ala Tabor

“…Therefore, chitinase 3 emerges as a viable vaccine candidate, holding promise for its integration into a multiantigenic vaccine against R. microplus.…”
Get full text

Towards a More Efficient Design of High Temperature Concentrating Solar Power Plant With Cascaded Thermal Energy Storage by Brenda Hernandez Corona, Thomas Fasquelle, Muhammad Abdullah, Nicolas Lopez Ferber, Jean-Francois Hoffmann, Mathieu Martins, Ahmad Mayyas, Nicolas Calvet

“…The methodology incorporates evaluating various combinations of solar block, TES, and power block integration. Combinations are selected from a comprehensive literature review. …”
Get full text

Effect of Temperature on Synthesis of Hydroxyapatite/Chitosan Composite Using the <i>In-Situ</i> Method as a Heavy Metal Adsorbent by Novesar Jamarun, Tri Yupi Amirullah, Syukri Syukri, Arika Prasejati, Wulandari Wulandari, Sintia Caniago, Nabiila Ayyu Tricahyani

“…The result indicated successful integration of HAp and CTS, with a crystallite size of 13.82 nm in the 65 °C composite. …”
Get full text

Unveiling Prevalence, Risk Factors, and Outcomes of Hepatitis D Among Vulnerable Communities in Romania by Liana Gheorghe, Speranta Iacob, Irma Eva Csiki, Mihaela Ghioca, Razvan Iacob, Ileana Constantinescu, Bogdan Chiper, Laura Huiban, Cristina Muzica, Irina Girleanu, Nicoleta Tiuca, Sorina Diaconu, Daniela Larisa Sandulescu, Ion Rogoveanu, Andra Iulia Suceveanu, Florentina Furtunescu, Corina Pop, Anca Trifan

“…Psychiatric comorbidities were more prevalent among HDV-positive patients, highlighting the need for integrated care. Conclusions: This study underscores the urgent need for targeted public health interventions, including enhanced screening, education, and access to novel antiviral therapies like bulevirtide to address the significant burden of HBV/HDV co-infection in Romania.…”
Get full text

Synergistic mapping of urban tree canopy height using ICESat-2 data and GF-2 imagery by Xiaodi Xu, Ya Zhang, Peng Fu, Chaoya Dang, Bowen Cai, Qingwei Zhuang, Zhenfeng Shao, Deren Li, Qing Ding

“…To achieve UTCH mapping at a resolution of 4 m, a synergistic model integrating data from the GF-2 and ICESat-2 grid-based canopy height was constructed using the Random Forest technique. …”
Get full text

Quality by Design-Based Methodology for Development of Titanate Nanotubes Specified for Pharmaceutical Applications Based on Risk Assessment and Artificial Neural Network Modeling by Ranim Saker, Géza Regdon, Krisztina Ludasi, Tamás Sovány

“…Results: This analysis is presented as an integrated pathway for titanate nanotube preparation and utilization in a proper way that meets the strict requirements of pharmaceutical systems (quality, safety, and efficacy). …”
Get full text

Introducing the Index of Response to Stimulation (IRES): A Novel Metric for Assessing Vagus Nerve Stimulation Outcomes in Drug-Resistant Epilepsy by Flavius-Iuliu Urian, Corneliu Toader, Razvan-Adrian Covache Busuioc, Antonio-Daniel Corlatescu, Horia Petre Costin, Gabriel Iacob, Alexadru Vlad Ciurea

“…<i>Conclusions</i>: The study confirms the IRES to be a valid tool for the assessment of the impact of VNS on drug-resistant epilepsy and promotes it as an integral part of the evaluation of the patient for personalized therapy. …”
Get full text

Meso Hybridized Silk Fibroin Watchband for Wearable Biopotential Sensing and AI Gesture Signaling by Xiao Wang, Changsheng Lu, Zerong Jiang, Guangwei Shao, Jingzhe Cao, Xiang Yang Liu

“…The flexible FM electrodes are created by integrating Mo‐Au FM into 2D‐interconnected networks. …”
Get full text

Agroforestry systems favor bat conservation but only when old and grazed by Manon Edo, Martin H. Entling, Felix Herzog, Kira Noe, João HN Palma, Ayla Seithe, Will Simonson, Jo Smith, Anja Weiler, Verena Rösch

“…By combining trees with crops (silvoarable systems) or livestock (silvopastoral systems), agroforestry re-integrates structural diversity into agricultural areas that could have beneficial effects on biodiversity. …”
Get full text

Recent plastic technologies development of basal texture control to improve the property of wrought Mg alloys-a review by Xiaoyu Feng, Lifei Wang, Xiang Chen, Kunkun Deng, Xiao Wang, Liuwei Zheng, Hongxia Wang, Qiang Zhang, Ho Kwon, Bin Xing, Kwang Seon Shin

“…The beneficial effects of texture control on the mechanical characteristics, formability, and corrosion resistance of Mg alloys were elucidated by integrating twinning, recrystallization, and non-basal slip processes. …”
Get full text

Fragmenstein: predicting protein–ligand structures of compounds derived from known crystallographic fragment hits using a strict conserved-binding–based methodology by Matteo P. Ferla, Rubén Sánchez-García, Rachael E. Skyner, Stefan Gahbauer, Jenny C. Taylor, Frank von Delft, Brian D. Marsden, Charlotte M. Deane

“…It is therefore likely to further benefit future drug design campaigns and be integrated in future pipelines. Graphical Abstract…”
Get full text

Restless Legs Syndrome: A Comprehensive Review of Current Treatment Methods and the Disease's Impact on Quality of Life by Natalie Papachristoforou, Natalia Tekiela, Daria Michałka, Zuzanna Gałuszka, Monika Makar, Tomasz Bartuś, Emilia Bąk, Justyna Głowacka, Aleksandra Kocjan, Radosław Chmiel

“…The condition constrains individualized management, integrating non-pharmacological forms of treatment with pharmacological therapies to improve patient outcomes and reduce dependence on medication.   …”
Get full text

Selenium’s Role in Plant Secondary Metabolism: Regulation and Mechanistic Insights by Yan Zhou, Kaiqin Nie, Lulu Geng, Yixin Wang, Linling Li, Hua Cheng

“…The present study aims to elucidate the mechanisms of Se absorption, transport, and metabolism in plants under Se-rich conditions and to investigate the impact of various Se biofortification methods on the content of plant secondary metabolites. By integrating existing research progress, this paper will delve into the potential molecular regulatory mechanisms of Se on plant secondary metabolism, aiming to unravel the interplay between Se and plant secondary metabolism. …”
Get full text

Demineralized Freeze-Dried Bovine Cortical Bone: Its Potential for Guided Bone Regeneration Membrane by David B. Kamadjaja, Achmad Harijadi, Pratiwi Soesilawati, Eny Wahyuni, Nurul Maulidah, Akhsanal Fauzi, Fika Rah Ayu, Roberto Simanjuntak, R. Soesanto, Djodi Asmara, Andra Rizqiawan, Peter Agus, Coen Pramono

“…However, cross-linking of collagen fibrils was associated with poorer tissue integration and delayed vascular invasion. Objective. …”
Get full text

Proteomic Characterization of Liver Cancer Cells Treated with Clinical Targeted Drugs for Hepatocellular Carcinoma by Hezhou Long, Jiafu Zhou, Changxia Zhou, Shuyu Xie, Jingling Wang, Minjia Tan, Junyu Xu

“…Furthermore, through the integration of clinical phosphorylation site data, we identified several phosphorylation sites that exhibited higher abundance in tumor tissues compared to adjacent non-tumor tissues. …”
Get full text

Assessing Macrophyte and Ecosystem Service Changes in Shallow Eutrophic Coastal Waters Using Remote Sensing Methods by Johanna Schumacher, David Horn, Gabriela Escobar-Sánchez, Greta Markfort, Gerald Schernewski, Mario von Weber

“…Our aerial drone detected macrophytes up to a depth of 3 m that could be integrated into the existing macrophyte monitoring scheme of the Water Framework Directive. …”
Get full text

A Wireless Power Conversion Chain With Fully On-Chip Automatic Resonance Tuning System for Biomedical Implants by Mohammad Javad Karimi, Menghe Jin, Catherine Dehollain, Alexandre Schmid

“…This paper presents a wireless power conversion system designed for biomedical implants, with integrated automatic resonance tuning. The automatic tuning mechanism improves power transfer efficiency (PTE) by finely tuning the resonant frequency of the power link and maximizing the rectified voltage. …”
Get full text

Challenges and future perspectives of sustainable supplements, functional foods, and nutrigenomics in athletic performance by Flores Naselli, Paola Sofia Cardinale, Sonya Vasto, Patrizia Proia, Sara Baldassano, Fabio Caradonna

“…The necessary approach must be integrated into food production, distribution, and consumption to meet current nutritional needs. …”
Get full text

Four Decades of Glaucoma in Primary Care: A Comprehensive Bibliometric Review (1978-2024) by Maiya Taushanova, Lyudmila Yermukhanova, Fatima Bagiyarova, Zhanna Zhussupova, Venera Baisugurova

“…The findings highlight the importance of an integrated approach that includes educating primary care providers, adopting advanced diagnostic technologies, and actively involving patients in their care and monitoring. …”
Get full text