Mechanisms of Resistance to Trastuzumab and Novel Therapeutic Strategies in HER2-Positive Breast Cancer by Andrea L. A. Wong, Soo-Chin Lee

“…While anti-HER2 agents such as trastuzumab and lapatinib are integral to the treatment of HER2-positive breast cancer, intrinsic and secondary resistance pose a significant challenge, underscoring the need to develop novel anti-HER2 therapies. …”
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Anomaly Detection and Root Cause Analysis for Energy Consumption of Medium and Heavy Plate: A Novel Method Based on Bayesian Neural Network with Adam Variational Inference by Qiang Guo, Fenghe Li, Hengwen Liu, Jin Guo

“…This paper proposes a comprehensive diagnostic framework for detecting anomalies, conducting causal analysis, and tracing root causes of energy consumption in medium and heavy plate manufacturing, integrating process mechanisms, expert knowledge, and industrial big data. …”
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Discussion on the mechanism of HER2 resistance in esophagogastric junction and gastric cancer in the era of immunotherapy by Yan Zhang, Wenxuan Fan, Fei Su, Xiaoling Zhang, Yunyi Du, Weiling Li, Yangjun Gao, Wenqing Hu, Jun Zhao

“…Furthermore, the review discusses the Novel therapeutic approaches, including the use of antibody-drug conjugates (ADCs) and combination therapies are assessed for their potential to enhance outcomes. By integrating recent research findings and clinical trials, this review aims to provide oncologists and researchers with insights into developing more effective treatments for patients with drug-resistant HER2-positive G/GEJ cancer.…”
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The Moral Psychological Justification of Anger: An Exploration of Self-Respect and Recognition by Jinjin Zhang, Zhiheng Xiong, Hao Zheng, Xiangzhen Ma

“…This paper argues for a shift in focus from the outcomes of anger to its moral and psychological foundations. By integrating insights from psychological research, this study posits that the fundamental nature of anger is intrinsically linked to the quest for recognition. …”
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A Robust Control Method for Lateral Stability Control of In-Wheel Motored Electric Vehicle Based on Sideslip Angle Observer by Yaxiong Wang, Feng Kang, Taipeng Wang, Hongbin Ren

“…This paper investigates the longitudinal and lateral integrated control through the active front steering and yaw moment control systems considering the saturation characteristics of tire forces. …”
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Recent Advances in Biopesticide Research and Development with a Focus on Microbials [version 4; peer review: 3 approved, 1 approved with reservations] by Dennis Ndolo, Jing Ge, Debbie Muir, Lawrence Malinga, Kahsay Tadesse Mawcha

“…It discusses (i) the various microbial biopesticide formulations, (ii) the mode of microbial biopesticide action, (iii) the factors that affect the potential efficacy of biopesticides, (iv) challenges to the adoption of microbial biopesticides, and (v) the role of microbial biopesticides in Integrated Pest Management programs. Finally, advancements in application techniques, as well as future research directions and gaps, are highlighted.…”
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Design and Implementation of Attention-Based CR System in the Context of Big Data by Zheyi Wang, Yanli Kuang, Xin Lyu

“…Therefore, an improved deep factor decomposition machine algorithm combining adaptive regularization and attention mechanisms is proposed, and big data components are integrated to enable the algorithm to support more data input types. …”
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High Step-Up ZVT Converter Based on Active Switched Coupled Inductors by Yu Tang, Haisheng Tong, Raheel Afzal, Yingjun Guo

“…The coupled inductors can realize relatively high voltage gain with appropriate turns ratio while all magnetic components can be integrated in one core. In addition, thanks to the leakage inductance, the reverse recovery problem of diodes is resolved. …”
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Fabrication of Hybrid Diamond and Transparent Conducting Metal Oxide Electrode for Spectroelectrochemistry by Jingping Hu, James Hodge, Arthur J. Boff, John S. Foord

“…A novel diamond transparent electrode is constructed by integrating conductive diamond film and transparent conducting metal oxide to combine the superior electrochemical properties of diamond and the electrical conductivity of transparent metal oxide (TCO). …”
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EMISSIONS MONITORING OF HEAVY METALS AND THEIR COMPOUNDS RESULTED FROM COMBUSTION PROCESSES IN CLINKER KILNS IN ROMANIA by CRISTIAN CIOBANU, GHEORGHE VOICU, MAGDALENA – LAURA TOMA, PAULA TUDOR

“…In addition, the list of over 100 types of waste that can be co-processed can be found in integrated authorizations of cement plants. However, the level of heavy metals in the combustion gases was in allowed limits. …”
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Advancements in Cardiac Amyloidosis Treatment by Tarek Ziad Arabi, Abdullah Shaik, Ahmed El-Shaer, Omar Al Tamimi, Eman Nayaz Ahmed, Mohamad S. Alabdaljabar, Ahmad Safdar, Ali Mushtaq

“…Future strategies should focus on integrating novel gene-editing therapies, expanding access to diagnostics, and enhancing multidisciplinary care models to improve outcomes. …”
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Two-layer optimization model of distribution network line loss considering the uncertainty of new energy access by Xiping Ma, Xiping Ma, Xiaoyang Dong, Haitao Xiao, Yaxin Li, Rui Xu, Kai Wei, Juanjuan Cai, Juan Wei

“…The integration of a distributed generator (DG) into the distribution network alters the topology structure and power flow distribution, subsequently causing changes in network loss. …”
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Fatigue Crack Propagation Behavior of RC Beams Strengthened with CFRP under High Temperature and High Humidity Environment by Dongyang Li, Peiyan Huang, Guang Qin, Xiaohong Zheng, Xinyan Guo

“…Numerical and experimental methods were applied to investigate fatigue crack propagation behavior of reinforced concrete (RC) beams strengthened with a new type carbon fiber reinforced polymer (CFRP) named as carbon fiber laminate (CFL) subjected to hot-wet environment. J-integral of a central crack in the strengthened beam under three-point bending load was calculated by ABAQUS. …”
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A Reconstruction Approach for Imaging in 3D Cone Beam Vector Field Tomography by T. Schuster, D. Theis, A. K. Louis

“…3D cone beam vector field tomography (VFT) aims for reconstructing and visualizing the velocity field of a moving fluid by measuring line integrals of projections of the vector field. The data are obtained by ultrasound measurements along a scanning curve which surrounds the object. …”
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Orientalist Encounters at School: Security and Inclusion in the Education of Syrian Refugee Children in Istanbul by Şule Can Sayar, Taha Baran

“…Currently, one of the most significant aspects of the integration process of refugees in Turkey is the education of refugee students. …”
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An Empirical Likelihood Ratio-Based Omnibus Test for Normality with an Adjustment for Symmetric Alternatives by Chioneso Show Marange, Yongsong Qin

“…We first transform the raw data via a jackknife transformation technique by deleting one observation at a time. The probability integral transformation was then applied on the transformed data, and under the null hypothesis, the transformed data have a limiting uniform distribution, reducing testing for normality to testing for uniformity. …”
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An Analysis of the Optimal Multiobjective Inventory Clustering Decision with Small Quantity and Great Variety Inventory by Applying a DPSO by Shen-Tsu Wang, Meng-Hua Li

“…The obtained clustering results should satisfy the inventory objective equation, which consists of different objectives such as total cost, backorder rate, demand relevance, and inventory turnover rate. This study integrates the above four objectives into a multiobjective equation, and inputs the actual inventory items of the enterprise into DPSO. …”
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Litiasis vesicular en niño e indicación de tratamiento quirúrgico. Presentación de un caso by Jorge Luís Estepa Pérez, Tahiluma Santana Pedraza, Juan Carlos Estepa Torres

“…<p>Se presenta el caso de un paciente de 9 años de edad, sexo masculino, boliviano, natural de Yacuiba, departamento de Tarija, con antecedentes de padecer de anemia en su etapa de lactante, que acudió con su mamá a la consulta de Cirugía General del Hospital Integral Comunitario Rubén Zelaya por  presentar trastornos dispépticos, deposiciones diarreicas, dolor abdominal en ocasiones, con un tiempo de evolución de 6 meses. …”
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Analysis of Vibration Control of Nonlinear Beam Using a Time-Delayed PPF Controller by Yueli Chen, Juhong Ge

“…Time delays in the control loop are taken into consideration to study their effects on the controller performance and the stable region. The integral iterative method is conducted to obtain a second-order approximate solution and the corresponding amplitude equations for the considered system. …”
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High-resolution gridded dataset of China’s offshore wind potential and costs under technical change by Kangxin An, Wenjia Cai, Xi Lu, Can Wang

“…This study addresses this gap by employing a consistent assessment framework that integrates GIS analysis, a wind reanalysis model, a component-based cost model and scenario analysis. …”
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