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6461
Mathematical modelling-based blockchain with attention deep learning model for cybersecurity in IoT-consumer electronics
Published 2025-02-01“…Employing regular software updates, secure authentication protocols, and strong encryption are indispensable approaches to guarantee the integrity and privacy of user details. Drones offer users a bird's-eye view that can be started and implemented anywhere and anytime. …”
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6462
Targeting early tau pathology: probiotic diet enhances cognitive function and reduces inflammation in a preclinical Alzheimer’s model
Published 2025-01-01“…Behavioral assessments were conducted at 13–14 months, followed by analysis of brain inflammation, blood-brain barrier integrity, and GSK-3β activation. Results Rats expressing pseudophosphorylated tau displayed impairment in spatial Y-maze (F 1,39 = 4.228, p = 0.046), spontaneous object location (F 1,39 = 6.240, p = 0.017), and olfactory discrimination (F 1,39 = 7.521, p = 0.009) tests. …”
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6463
Ultrasonic/compound enzyme extraction, comparative characterisation and biological activity of Lonicera macranthoides polysaccharides
Published 2025-03-01“…The ultrasound-assisted method enhanced the stability and bioactivity of LMP, with improved water- and oil-holding capacities and the integrity of the active groups. Our findings demonstrate that the extraction method significantly influences the structural and functional properties of LMP, suggesting that UAE may be a more effective approach for extracting bioactive polysaccharides with potential applications in medicine and nutrition.…”
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6464
Effects of deoxynivalenol contaminated corn distiller's dried grains with solubles on growth performance, body composition, immunological response, and gastrointestinal health in y...
Published 2025-01-01“…In conclusion, feeding DON-contaminated DDGS at higher inclusion levels (15% and 20%) with final diet DON concentrations exceeding 8.9 ppm over 28 days adversely affects growth performance, immune function, and gut integrity in young pullets.…”
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6465
Gene Ontology and Expression Studies of Strigolactone Analogues on a Hepatocellular Carcinoma Cell Line
Published 2019-01-01“…Strigolactone (SL) is a novel class of phytohormone, whose analogues have been reported to possess anticancer properties on a panel of human cancer cell lines through inducing cell cycle arrest, destabilizing microtubular integrity, reducing damaged in the DNA repair machinery, and inducing apoptosis. …”
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6466
UTE MRI technical developments and applications in osteoporosis: a review
Published 2025-02-01“…Accurate evaluation of bone requires information about its components (mineral, collagen, water) and structure (cortical porosity, trabecular microstructure), which are all important in maintaining the mechanical integrity of bone. Magnetic resonance imaging (MRI) is routinely used to diagnose soft tissue diseases, but bone is “invisible” with clinical MRI due to its short transverse relaxation time. …”
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6467
Asiaticoside Attenuates Chronic Restraint Stress-Induced Hippocampal CA1 Neuronal Ferroptosis via Activating BDNF/Nrf2/GPX4 Signaling Pathway
Published 2025-02-01“…Transmission electron microscopy (TEM) further confirmed that asiaticoside preserved mitochondrial integrity in CA1 neuronal cells.Conclusion: In conclusion, our findings suggest that asiaticoside exerts its antidepressant-like effects through the modulation of BDNF/Nrf2/GPX4 signaling pathway against neuronal ferroptosis in the hippocampal CA1 region.Keywords: asiaticoside, antidepressant, ferroptosis, BDNF, Nrf2, GPX4…”
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6468
Isolation and characterization of novel peptides from fermented products of Lactobacillus for ulcerative colitis prevention and treatment
Published 2022-11-01“…One of those peptides named T24 (PVLGPVRGPFPLL) exhibited the most remarkable anti-colitis activity by preventing tight junction protein loss, maintaining epithelial barrier integrity, and promoting cell proliferation during in vitro and in vivo studies by regulating mitogen-activated protein kinase signaling pathways. …”
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6469
Metal complexes in cells: from design of catalytic antioxidants to imaging metal ions and designing metal-based probes in X-ray fluorescence and IR-imaging, a multidisciplinary col...
Published 2024-03-01“…Methods to quantify the SOD-like activity, out of cellular context and in cells, and analysis of the integrity of the metal-based antioxidant in cells (through ion mobility coupled with mass spectrometry) will be described. …”
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6470
Realizing collective action in agency-constrained contexts: the case of the Community Fish Refuges in Cambodia
Published 2025-01-01“…Their sustained physical integrity and productivity as multiple-use systems hinge on communities’ ability to manage these systems collectively. …”
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6471
Biotechnological Phytocomplex of <i>Zanthoxylum piperitum</i> (L.) DC. Enhances Collagen Biosynthesis In Vitro and Improves Skin Elasticity In Vivo
Published 2025-01-01“…<b>Conclusions</b>: ZPP shows promise as a biotechnological agent for skin health, particularly in supporting collagen integrity, ECM stabilization, and cellular resilience under stress. …”
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6472
Age- and sex-specific differences in myocardial sympathetic tone and left ventricular remodeling following myocardial injury
Published 2025-01-01“…Conversely, females maintain sympathetic integrity, independent of sex hormones. Our results suggest a biological advantage of female sex in post MI recovery. …”
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6473
The potential impact of glycine supplementation on the process of aging
Published 2025-02-01“… Aging is a multifactorial process characterized by the progressive loss of cellular integrity, metabolic flexibility, mitochondrial function, and the gradual accumulation of oxidative and inflammatory damage. …”
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6474
Enhanced characterization of non-metallic inclusions in ultra-high-strength steels using advanced synchrotron-based X-ray absorption spectroscopy and chemometric analysis
Published 2025-03-01“…This approach maintains the integrity of the results while uncovering NMI behaviors, including the identification of new calcium phases. …”
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6475
Antibacterial Potential of Honeybee Venom and <i>Monascus purpureus</i> Extracellular Metabolites Against Multidrug-Resistant Pathogenic Bacteria
Published 2024-12-01“…Scanning electron microscopy (SEM) revealed that BV and RD extracts disrupted the bacterial plasma membrane, suggesting that the bioactive compounds penetrate the bacterial cell wall and alter its integrity. Furthermore, GC–MS-based analysis revealed that the chemical composition of BV and RD extracts exhibited highly diverse structures, including complex polycyclic systems, porphyrins, steroids, and esters. …”
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6476
Advancements in Nanotechnology for Enhanced Food Safety and Hygiene: Pathogen Detection, Smart Packaging, and Preservation Applications
Published 2024-12-01“…This review also explores the potential of utilizing biowaste for green synthesis of nanoparticles, which could further reduce environmental impact. By integrating cutting-edge detection methods, improving packaging solutions, and addressing safety and sustainability challenges, nanotechnology has the potential to transform food safety and hygiene practices. …”
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6477
One-pot synthesis and characterization of a BSA-Cu2S/CuS quantum dots drug delivery system based on biuret’s reaction
Published 2025-01-01“…Fourier-transform infrared (FTIR) spectroscopy confirmed the structural integrity of BSA after functionalization, while x-ray diffraction (XRD) analysis verified the formation of CuS and Cu _2 S crystals. …”
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6478
Neuromuscular electrical stimulation training induces myonuclear accretion and hypertrophy in mice without overt signs of muscle damage and regeneration
Published 2025-02-01“…Histological investigations were performed to assess the impact of NMES on MuSC number and status, myonuclei content and muscle tissue integrity, typology and size. Results NMES led to a robust proliferation of MuSCs and myonuclear accretion in the absence of overt signs of muscle damage/regeneration. …”
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6479
Cannabinoid receptor 2 selective agonist ameliorates adjuvant-induced arthritis by modulating the balance between Treg and Th17 cells
Published 2025-01-01“…Flow cytometry, in vitro differentiation assays, and Western blot analysis were performed to examine Th17 and Treg cells, as well as signaling pathways involved in their differentiation.ResultsHU-308 reduced paw swelling, lowered spleen index, and preserved joint integrity in AIA mice, mitigating inflammatory cell infiltration and bone erosion. …”
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6480
Effects of dietary supplementation with novel organic rare earths on growth performance, gut and liver health, gut microbiota in golden pompano
Published 2025-03-01“…In addition, the novel organic rare earths enhanced the tight junctions between intestinal epithelial cells to maintain the integrity of the intestinal barrier and reduced intestinal inflammation. …”
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