Enhanced targeted treatment of cervical cancer using nanoparticle-based doxycycline delivery system by Sadia Anjum, Ayesha Akhtar, Saleh M. Aldaqal, Maisa S. Abduh, Hammad Ahmad, Riaz Mustafa, Faiza Naseer, Maryam Sadia, Tahir Ahmad

“…Stability tests confirmed the maintenance of nanoparticle integrity and a consistent drug release profile over three months. …”
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Ningxiang pig-derived Lactobacillus reuteri improves the gut health of weaned piglets by regulating intestinal barrier function and cytokine profiles by Qian Xie, Mei Yang, Qing Duanmu, Meng Kang, Jing Wang, Bi E Tan

“…This study aimed to evaluate the effects of Lactobacillus reuteri (L. reuteri) supplementation on growth performance, intestinal immunity, and intestinal barrier integrity in weaned piglets. In this investigation, fourteen healthy weaned piglets of similar age and weight, were randomly assigned to two groups (n = 7), receiving either normal saline (Control group) or L. reuteri (L-treatment group) over a 16-day period. …”
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High-level biosynthesis and purification of the antimicrobial peptide Kiadin based on non-chromatographic purification and acid cleavage methods by Liangjun Zheng, Fengyi Yang, Chen Wang, Muhammad Zafir, Zishuo Gao, Pilong Liu, Fatma A. El-Gohary, Xin Zhao, Huping Xue

“…Notably, Kiadin demonstrated significant post-antibiotic effects by disrupting bacterial membrane integrity, inducing cytoplasmic leakage, and inhibiting biofilm formation in E. coli K88 and S. aureus Mu50, without cytotoxicity towards mouse macrophages. …”
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The Effects of Lutein and Zeaxanthin Supplementation on Brain Morphology in Older Adults: A Randomized, Controlled Trial by Catherine M. Mewborn, Cutter A. Lindbergh, B. Randy Hammond, Lisa M. Renzi-Hammond, L. Stephen Miller

“…We hypothesized that the supplement group would increase, maintain, or show attenuated loss in hypothesized regions-of-interest (ROIs) while the placebo group would show age-related declines in brain structural integrity over the course of the trial. While results showed age-related declines for frontal and temporal gray and white matter volumes, as well as fornix white matter microstructure across both groups, only minimal differences were found between the supplement and placebo groups. …”
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Numerical Analysis on the Load Sharing Performance of Long-Short CFG Pile Composite Foundation Subjected to Rotation of Adjacent Retaining Wall by Bantayehu Uba Uge, Yuancheng Guo, Yunlong Liu

“…The soil movement disturbs the load sharing performance and structural integrity of cement-fly ash-gravel (CFG) pile composite foundations existing in the vicinity, which merits considerable research work. …”
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qTrustNet Virtual Private Network (VPN): Enhancing Security in the Quantum Era by Hyoungsub Shim, Bongho Kang, Haejung Im, Duhyun Jeon, Seok-Min Kim

“…At the core of qTrustNet VPN’s enhanced security is the integration of a Post-Quantum Cryptography (PQC) algorithm, developed by the National Institute of Standards and Technology (NIST). …”
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“Scarlet Cloak and the Forest Adventure”: a preliminary study of the impact of AI on commonly used writing tools by Barbara Bordalejo, Davide Pafumi, Frank Onuh, A. K. M. Iftekhar Khalid, Morgan Slayde Pearce, Daniel Paul O’Donnell

“…To exacerbate this problem, traditional AI detectors like Turnitin and GPTZero struggle to reliably differentiate between legitimate paraphrasing and AI generation, undermining their utility for enforcing academic integrity. The study concludes by urging educators to focus on managing interactions with AI in academic settings rather than outright banning its use. …”
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Role of cardiolipin in skeletal muscle function and its therapeutic implications by Youngbum Yoo, MyeongHoon Yeon, Mee-Sup Yoon, Young-Kyo Seo

“…Abstract Cardiolipin, a unique phospholipid predominantly present in the inner mitochondrial membrane, is critical for maintaining mitochondrial integrity and function. Its dimeric structure and role in supporting mitochondrial dynamics, energy production, and mitophagy make it indispensable for skeletal muscle health. …”
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Combining extracellular matrix proteome and phosphoproteome of chickpea and meta‐analysis reveal novel proteoforms and evolutionary significance of clade‐specific wall‐associated e... by Kanika Narula, Arunima Sinha, Pooja Choudhary, Sudip Ghosh, Eman Elagamey, Archana Sharma, Atreyee Sengupta, Niranjan Chakraborty, Subhra Chakraborty

“…Abstract Extracellular matrix (ECM) plays central roles in cell architecture, innate defense and cell wall integrity (CWI) signaling. During transition to multicellularity, modular domain structures of ECM proteins and proteoforms have evolved due to continuous adaptation across taxonomic clades under different ecological niche. …”
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Insights into corrosion behavior of AlCrFeTi and AlCrFeTiY coating for fuel cladding in static and flowing liquid lead bismuth at 550°C by Jingyi Liang, Wei Zhang, Qingyu Li, Ke Zhao, Jun Xiao, Jijun Yang, Shaoyu Qiu, Sheng Huang

“…Besides, structural integrity of AlCrFeTi was well preserved after erosion test in flowing lead bismuth (∼2 m/s) for 1000 h, localized bulges existed in eroded AlCrFeTiY coating. …”
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Efficacy of human umbilical cord mesenchymal stem cell in the treatment of neuromyelitis optica spectrum disorders: an animal study by Chunran Xue, Haojun Yu, Xuzhong Pei, Xiaoying Yao, Jie Ding, Xiying Wang, Yi Chen, Yangtai Guan

“…Then, disease progression, immune responses, and blood–brain barrier integrity were evaluated. Additionally, we tested the effects of hUC-MSCs on astrocyte viability and apoptosis using an aquaporin 4 (AQP4) IgG and complement-induced cytotoxicity model in vitro. …”
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Multi-omics analyses identify gut microbiota-fecal metabolites-brain-cognition pathways in the Alzheimer’s disease continuum by Han Zhao, Xia Zhou, Yu Song, Wenming Zhao, Zhongwu Sun, Jiajia Zhu, Yongqiang Yu

“…Integration of these multi-omics changes revealed significant associations between microbiota, metabolites, neuroimaging, and cognition. …”
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Stability of reinforcements (CrB2/TiB2) and lubricants (C/MoS2) in Cu matrix during the sintering process by Chen Zhang, Lei Jia, Jia-mei Zhang, Wu Pan, Zhen-lin Lu, Zhi-guo Xing

“…Finally, the strengthening effect of CrB2 and TiB2 along with the lubricating effect of graphite (C) are promise to work in Cu matrix from the viewpoint of crystal structure integrity.…”
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Osteoperiosteal versus osteochondral for autologous transplantation in the treatment of large cystic osteochondral lesions of the talus by Lequan Liu, Jiangtao Jin, Jinping Pan, Huikang Guo, Sen Li, Jisheng Li, Zheng Zhang

“…The Ankle Activity Score (AAS), time to return to sports activity (RTA), rate of return to sports level, complications, and results of a subjective evaluation were also collected. The integrity of subchondral bone and the quality of repaired cartilage were evaluated using the Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score 12 months postoperatively. …”
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When Things Are Not as They Appear: Assessing the Adequacy of Cluster Randomization When Outcome Events Are Rare at Baseline by Veronica Dinaj-Koci, Nanika Brathwaite, Lynette Deveaux, Sonya Lunn, Lesley Cottrell, Carole Harris, Bonita Stanton, Xiaoming Li, Sharon Marshall, Perry Gomez, Xinguang Chen

“…Not considering such individual differences could impact the integrity of trial outcomes.…”
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Not all is lost: resilience of microbiome samples to freezer failures and long-term storage by M. Fabiola Pulido Barriga, James W. J. Randolph, Sydney I. Glassman

“…However, freezer malfunctions can jeopardize data integrity. To evaluate the impact of an unexpected −80°C freezer failure and the recoverability of thawed soil samples, we extracted DNA and compared it to long-term DNA stored at −20°C and original 16S and ITS2 sequencing data collected before the malfunction. …”
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High performance synthetic fiber-reinforced concrete mixed with nanoparticles: A proof-of-concept green railway sleeper product by Radhika Sridhar, Satjapan Leelatanon, Monthian Setkit, Thanongsak Imjai, Elhem Ghorbel, Boksun Kim

“…To further enhance structural integrity, the study incorporates fibers such as polypropylene fiber (PPF) and polyvinyl alcohol fiber (PVA) at a constant volume fraction of 0.5%. …”

Experimental Approach for the Evaluation of the Performance of a Satellite Module in the CanSat Form Factor for In Situ Monitoring and Remote Sensing Applications by Juan Sebastián Rodríguez, Andrés Yarce Botero, Diego Valle, Julián Gálvez- Serna, Francisco Botero

“…To know the dynamic response and ensure the structural integrity of the satellite module, shock, oscillation, and sinusoidal tests were applied through a shaker. …”
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Impact of HIV on HPV-related cancers in men who have sex with men: a review by Zixuan Zhang, Zixuan Zhang, Yuying Xing, Yuying Xing, Tingdan Gong, Wanlin Li, Siwei Zhang, Lanlan Wei

“…We integrated epidemiological data from the past five years and discussed diagnosis and treatment strategies. …”
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Systematic Review and Meta-Analysis of Remineralizing Agents: Outcomes on White Spot Lesions by Ana Josefina Monjarás-Ávila, Louis Hardan, Carlos Enrique Cuevas-Suárez, Norma Verónica Zavala Alonso, Miguel Ángel Fernández-Barrera, Carol Moussa, Jamal Jabr, Rim Bourgi, Youssef Haikel

“…White spot lesions, the earliest stage of caries, compromise enamel’s esthetics and integrity. Remineralization therapies, both fluoride and non-fluoride based, aim to restore enamel, but limited comparative data exist on their effects on lesion depth and microhardness. …”
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