The Function of SUMOylation and Its Role in the Development of Cancer Cells under Stress Conditions: A Systematic Review by Qi Zhao, Ying Ma, Zugui Li, Kexin Zhang, Minying Zheng, Shiwu Zhang

“…Chemotherapeutic drugs and radiation used to treat these tumors mainly interfere with tumor metabolism, destroy DNA integrity, and inhibit protein synthesis. The upregulation of small ubiquitin-like modifier (SUMO) is a prevalent posttranslational modification (PTM) in various cancers and plays a critical role in tumor development. …”
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Discrete Element Simulation Analysis of the Bending and Toppling Failure Mechanisms of High Rock Slopes by Zhigang Meng, Yongli Hou, Longji Guo, Fengnian Wang, Kuiming Liu, Gan Qi, Juan Ma

“…Through evaluation of regional rock integrity parameters and rock soft and hard parameters, rock-mass strength based on Hoek Brown strength estimation criteria can be developed. …”
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<i>Epigynum auritum</i>-Derived Near-Infrared Carbon Dots for Bioimaging and Antimicrobial Applications by Wenfeng Shi, Jiahui Li, Junmei Pu, Guiguang Cheng, Yaping Liu, Shanshan Xiao, Jianxin Cao

“…The antimicrobial effect is likely attributed to the NIR-CDs disrupting the cell membrane integrity, leading to the leakage of the intracellular contents. …”
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Is the BCG Vaccine Safe for Undernourished Individuals? by Larissa Lumi Watanabe Ishikawa, Larissa Camargo da Rosa, Thais Graziela Donegá França, Raphael Sanches Peres, Fernanda Chiuso-Minicucci, Sofia Fernanda Gonçalves Zorzella-Pezavento, Alexandrina Sartori

“…Cellular immunity is critical for protection against tuberculosis, but its integrity is compromised during undernutrition. The present study was designed to evaluate if the attenuated mycobacterium BCG is a safe vaccine for undernourished individuals. …”
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Toxicological complexity of microplastics in terrestrial ecosystems by Fazal Ullah, Peng-Yang Wang, Saddam Saqib, Ling Zhao, Muhammad Ashraf, Aziz Khan, Wasim Khan, Adnan Khan, Yinglong Chen, You-Cai Xiong

“…The overview underscores a complex interplay between environmental and socio-economic systems, addressing the urgency of harnessing MPs pollution and protecting ecosystem integrity and sustainability.…”
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Genetics of Inflammatory Bowel Disease: Current Understanding and Future Directions by P. K. Chandra Sekar, R. Veerabathiran

“…These genetic variants, integral to IBD's etiology of IBD, have functional significance because they perturb immune regulation, compromise epithelial barrier integrity, and disrupt mucosal homeostasis, collectively contributing to intestinal inflammation through diverse mechanisms. …”
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Enhanced Peelability and Quality of Whiteleg Shrimp (<i>Litopenaeus vannamei</i>) Using Pulsed Electric Field (PEF) Treatment by Gyeong-Seo Park, Hyeon Seo, Han-Baek Lee, Ji-Won Lee, Hafiz Muhammad Shahbaz, Se-Ho Jeong, Dong-Un Lee

“…These findings indicate that PEF treatment is an efficient, non-thermal method for enhancing shrimp peeling processes while preserving textural integrity. PEF technology offers a promising alternative to traditional mechanical and thermal methods in the seafood processing industry.…”
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Change Detection and Incremental Updates for Multi-Source Road Networks Considering Topological Consistency by Xiaodong Wang, Dongbao Zhao, Xingze Li, Nan Jia, Li Guo

“…Collectively, our methods expedite the updating cycle of vector road network data and facilitate the seamless sharing and integrated utilization of multi-source road network data.…”
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Lipid Oxidation at the Crossroads: Oxidative Stress and Neurodegeneration Explored in <i>Caenorhabditis elegans</i> by Julia Tortajada-Pérez, Andrea del Valle Carranza, Cristina Trujillo-del Río, Mar Collado-Pérez, José María Millán, Gema García-García, Rafael Pascual Vázquez-Manrique

“…Lipid metabolism plays a critical role in maintaining cellular integrity, especially within the nervous system, where lipids support neuronal structure, function, and synaptic plasticity. …”
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Using artificial intelligence tools for automating the assessment of future computer science teachers' work by Oleksandr M. Spazhev, Oksana V. Klochko

“…In particular, the integration of the proposed system based on GitHub Copilot with learning management systems (LMS) and automated task verification systems. …”
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A Journey into the Complexity of Temporo-Insular Gliomas: Case Report and Literature Review by Manuel De Jesus Encarnacion Ramirez, Gervith Reyes Soto, Carlos Castillo Rangel

“…Conclusions: Temporo-insular gliomas (TIGs) necessitate a multidisciplinary strategy that integrates advanced imaging, meticulous surgical methods, and cutting-edge adjuvant therapies. …”
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Correlation between Post-Thaw Spermatozoa Quality of the Endangered Javan Banteng with OPN Gene Expression by Vincentia Trisna Yoelinda, Raden Iis Arifiantini, Dedy Duryadi Solihin, Muhammad Agil, Dedi Rahmat Setiadi, Tulus Maulana, Bambang Purwantara, Yohana Tri Hastuti, Jansen Manansang, Dondin Sajuthi

“…The OPN gene showed positive correlations with the progressive motility (r = 0.711, p = 0.048), viability (r = 0.822, p = 0.012), and acrosomal integrity (r = 0.665, p = 0.072) of Javan banteng spermatozoa after thawing. …”
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Reconstruction of Nasal Skin Cancer Defects with Local Flaps by A. C. Salgarelli, P. Bellini, A. Multinu, C. Magnoni, M. Francomano, F. Fantini, U. Consolo, S. Seidenari

“…Reconstruction of nasal defects must preserve the integrity of complex facial functions and expressions, as well as facial symmetry and a pleasing aesthetic outcome. …”
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Sustainability of the state system in the context of digital transformation by V. A. Kornilovich, K. A. Aramyan, A. V. Milekhin, A. V. Mironov

“…The impact of information and communication technologies on the functioning of society is manifested in maintaining the gap between formal and informal institutions, intensive introduction of innovations, launching new mechanisms of social inequality, and the like, as a result, the integrity of the social system is violated. The risk of loss of manageability of social processes increases due to the fact that the recommendations for authorities on digital transformation, as well as most scientific publications on the topic of digitalization of public administration do not contain a critical assessment of the ICT paradigm itself and the concepts, concepts and practices formed on its basis.…”
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Performance Comparison of Different Neuroimaging Methods for Predicting Upper Limb Motor Outcomes in Patients after Stroke by Jingyan Tao, Zhaoqing Li, Yang Liu, Jianhua Li, Ruiliang Bai

“…Several neuroimaging methods have been proposed to assess the integrity of the corticospinal tract (CST) for predicting recovery of motor function after stroke, including conventional structural magnetic resonance imaging (sMRI) and diffusion tensor imaging (DTI). …”
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Enhancing Safety in Nigeria's Oil and Gas Sector: A Fault Tree Analysis Approach by Mgbowaji Zacchaeus, John Nwenearizi Ugbebor, Ikechukwu Ozoemenam Agbagwa, Ochuko Felix Orikpete

“… The oil and gas industry, a cornerstone of the global energy supply, faces multifaceted challenges that threaten its operational integrity, environmental sustainability, and socio-economic contributions, particularly in regions like Nigeria where the sector's growth is pivotal to national development. …”
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Stabilizing milk-derived extracellular vesicles (mEVs) through lyophilization: a novel trehalose and tryptophan formulation for maintaining structure and Bioactivity during long-te... by Alan B. Dogan, Spencer R. Marsh, Rachel J. Tschetter, Claire E. Beard, Md R. Amin, L. Jane Jourdan, Robert G. Gourdie

“…However, maintaining integrity and bioactivity of EVs between Good Manufacturing Practice separation/filtration and end-user application remains a consistent bottleneck towards commercialization. …”
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Сryosurgery possibilities for nevus in intermarginal eyelid space by A.N. Steblyuk, V.E. Gunter, S.N. Sahnov, P.A. Khloponin, Е.V. Bykova, Zh.G. Litvinova

“…Depending on the size of the pathological formation, exposure duration, the frequency of application repetitions per session, the nevus regression occurred within 1.5–2.0 months with preserving the integrity of the eyelid intermarginal space and the eye functional condition. …”
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In-silico screening and analysis of missense SNPs in human CYP3A4/5 affecting drug-enzyme interactions of FDA-approved COVID-19 antiviral drugs by Amro A. Abdelazim, Mohamad Maged, Ahmed I. Abdelmaksoud, Sameh E. Hassanein

“…An ensemble of bioinformatics tools, [SIFT, PolyPhen-2, cadd, revel, metaLr, mutation assessor, Panther, SNP&GO, PhD-SNP, SNAP, Meta-SNP, FATHMM, I-Mutant, MuPro, INPS, CONSURF, GPS 5.0, MusiteDeep and NetPhos], identified a total of 94 variants (47 SNPs in CYP3A4, 47 SNPs in CYP3A5) to potentially impact the structural integrity as well as the activity of the CYP3A4/5 enzymes. …”
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Possibilities and limitations of applying ChatGPT in the educational process by Namesztovszk Zsolt B., Glušac Dragana R., Arsović Branka B., Kovacs Elvira I.

“…However, there are risks related to academic integrity issues, unfair learning assessment, inaccurate information, and over-reliance on AI. …”
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