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5741
Progress in Therapy Development for Amyotrophic Lateral Sclerosis
Published 2012-01-01“…These neuroinflammatory processes produce paracrine factors that detrimentally affect motor neurons, precipitating protein aggregation and compromising cytoskeletal integrity. The result is a loss of neuronal homeostasis and progressive die-back of motor axons culminating in death of the afflicted motor neurons. …”
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5742
Legal Regulation of Spreading Opinions and Beliefs through TV Broadcasting
Published 2021-07-01“…It has been stated that the right to information may be limited by law in the interests of national security, territorial integrity or public morality. The general characteristics of monitoring and supervisory powers of the National Council on Television and Radio Broadcasting have been provided. …”
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5743
Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice
Published 2015-01-01“…Multiple extracellular (pH, heat, oxidants, and detergents) or intracellular (DNA damage and Ca2+ overload) stress conditions trigger various types of the nuclear, endoplasmic reticulum (ER), cytoplasmatic, and mitochondrion-centered signaling events that allow cells to preserve the DNA integrity, protein folding, energetic, ionic and redox homeostasis, thus escaping from injury. …”
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5744
NATIONAL SECURITY AND BORDER MANAGEMENT IN WEST AFRICA: A STUDY OF NIGERIA-NIGER RELATIONS
Published 2024-07-01“…This paper intends to contribute to knowledge by arguing that Nigeria-Niger relations particularly border management is critical to the protection of the territorial integrity of the states from the activities of violent non-state actor. …”
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5745
Experimental Study of Dynamic Mechanics Characteristics of Saturated Marble under Low Temperature
Published 2021-01-01“…From −5°C to −20°C, the ice medium and marble matrix contract when cooled, and the microcracks and micropores caused by the phase transition gradually close during the contraction process, the integrity of the rock is restored, and the dynamic strength of the rock is increased. …”
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5746
Stolen Ukrainian universities: An invisible russian weapon
Published 2025-02-01“…By bringing attention to this “silent war on knowledge”, the paper underscores the urgency of addressing the misuse of stolen academic institutions by Russia to uphold the integrity of global academia and international law.…”
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5747
Challenges and Current Trends in Preventing Antimicrobial Resistance in EU Water Law Context
Published 2024-12-01“…This study advocates for a proactive, integrated approach to water policy that aligns regulatory actions with scientific advancements to protect public health and ecosystem integrity.…”
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5748
Endoscopic Type 1 Tympanoplasty: Evaluation of Clinical Success and Hearing Improvement
Published 2024-12-01“…Functional success was defined as a postoperative ABG of 20 dB, whereas the integrity of the graft determined clinical success. …”
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5749
Design and finite element analysis of an extractor machine for castor oil biodiesel production
Published 2025-01-01“…The machine was designed using appropriate design equations in the design analysis of the machine, and finite element analysis was conducted to determine the structural integrity, functionality and manufacturability of the system. …”
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5750
Shielding the Gut: Ghrelin and Ferrostatin-1’s Protective Role Against Sepsis-Induced Intestinal Ferroptosis
Published 2024-12-01“…<b>Objective:</b> This study investigates the therapeutic efficacy of ghrelin in alleviating sepsis-induced intestinal damage, focusing on its potential to inhibit ferroptosis and protect intestinal barrier integrity. <b>Methods:</b> This study evaluates the therapeutic efficacy of intraperitoneal ghrelin (80 μg/kg) and Ferrostatin-1 (5 mg/kg) using a cecal ligation and puncture (CLP) model in C57BL/6 mice to determine their potential in alleviating sepsis-induced intestinal damage. …”
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5751
Indicators of speed and strength abilities of young fencers 12-13 years old
Published 2022-12-01“…This is a guarantee of the integrity of the process of training athletes for the next stage of preliminary basic training. …”
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5752
Simulation and Prediction of Injection Pressure in CO2 Geological Sequestration Based on Improved LSO Algorithm and BP Neural Networks
Published 2022-01-01“…In order to avoid the occurrence of caprock integrity damage and gas escape due to injection pressure overrun in CO2 sequestration, an optimized back propagation (BP) neural network model based on Monte Carlo simulation (MCS) and an improved lion swarm optimization (ILSO) algorithm is proposed for the maximum sustainable injection pressure prediction. …”
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5753
The concept of public control over judges’ activity and the system of subjects of its implementation
Published 2019-06-01“…Summarizing the analysis of the system of public control subjects, their administrative powers and capabilities, the author has noted that their absolute majority, except the Public Integrity Council, is not endowed with real (or at least close to such) levers of influence on the processes in the judicial sector. …”
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5754
Short Telomere Length in Plasma of Sudanese Patients with Hepatocellular Carcinoma and Chronic Liver Diseases
Published 2024-12-01“… Background: Telomeres, a protective sequence of DNA at the end of chromosomes, are essential for the maintenance of chromosomal integrity and stability. With each cell division, telomeres are shortened until a critical length is reached. …”
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5755
Design and Development of a Bespoke Rotary Friction Welding Machine in Exploration of Joining Dissimilar Materials for Nuclear Applications
Published 2025-01-01“…Rotary friction welding is a solid-state welding process that can manufacture high-integrity joints between similar and dissimilar materials with short weld times. …”
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5756
Enhanced composite performance: Evaluating silane treatment on Cordia dichotoma Fibers
Published 2025-03-01“…Excessive silane concentrations negatively affected fiber integrity. This research highlights the potential of silane-treated CF in high-performance composite applications.…”
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5757
Inhibition of Staphylococcus aureus α-Hemolysin Production Using Nanocurcumin Capped Au@ZnO Nanocomposite
Published 2022-01-01“…The results showed that the prepared nanoparticles (Cur-Au@ZnO) served as an antibacterial agent and can destroy the bacterial cells by losing the cell wall integrity and penetrating the cytoplasmic membrane. …”
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5758
An In Vitro Comparative Study of the Push-out Bond Strengths of Various Endodontic Sealers to Radicular Dentin
Published 2023-10-01“…Background: The bond strength of an endodontic sealer to the root dentin is an important factor in maintaining the integrity of the root canal seal. The present study aimed to assess the push-out bond strength of three endodontic sealers used with the single-cone obturation technique. …”
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5759
Protective effects of blueberry anthocyanin extracts on hippocampal neuron damage induced by extremely low-frequency electromagnetic field
Published 2020-09-01“…Blueberry anthocyanin extracts supplementation inhibited the decrease in Nissl substance levels, cell membrane integrity, and mitochondrial membrane potential induced by ELF-EMF; prevented the increase in nitric oxide, malondialdehyde, and Ca2+ concentrations; suppressed superoxide dismutase and glutathione depletion; and enhanced the cognitive ability of the rats exposed to ELF-EMF. …”
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5760
The Effect of an Aqueous Extract of Teucrium polium on Glutathione Homeostasis In Vitro: A Possible Mechanism of Its Hepatoprotectant Action
Published 2010-01-01“…The effects of increasing concentrations (0.01–1 mg/mL) of aqueous extract of T. polium were assessed in cultured HepG2 cells following 24 hours incubation on (1) cellular integrity using (a) the Trypan blue exclusion assay, (b) the [di-methylthiazol-2yl]-2,5-diphenyl-tetrazoliumbromide (MTT) assay, and (c) the lactate dehydrogenase (LDH) assay; (2) glutathione redox state; and (3) glutathione peroxidase and glutathione reductase activities using a repeated measures experimental design. …”
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