α-Methyl-Tryptophan Inhibits SLC6A14 Expression and Exhibits Immunomodulatory Effects in Crohn’s Disease by Su Y, Li J, Chen Y, Bao J, Lei Z, Ma M, Zhang W, Liu Q, Xu B, Hu T, Hu Y

“…YongCheng Su,1,* Jiangquan Li,1,* Yijia Chen,2,* Jiachen Bao,2 Ziyu Lei,1 Miaomiao Ma,1 Wenqing Zhang,1 Qian Liu,3 Beibei Xu,4 Tianhui Hu,1,3 Yiqun Hu2 1Xiamen Key Laboratory for Tumor Metastasis, Cancer Research Center, School of Medicine, Xiamen University, Xiamen, Fujian, 361102, People’s Republic of China; 2Department of Gastroenterology, The National Key Clinical Specialty, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361004, People’s Republic of China; 3Integrated Chinese and Western Medicine Institute for Children Health & Drug Innovation, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, 330004, People’s Republic of China; 4Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, 518055, People’s Republic of China*These authors contributed equally to this workCorrespondence: Tianhui Hu, Xiamen Key Laboratory for Tumor Metastasis, Cancer Research Center, School of Medicine, Xiamen University, Xiamen, Fujian, 361102, People’s Republic of China, Email thu@xmu.edu.cn Yiqun Hu, Department of Gastroenterology, The National Key Clinical Specialty, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361004, People’s Republic of China, Email hyq0826@xmu.edu.cnIntroduction: Crohn’s disease (CD) is a chronic inflammatory condition of the intestines with a rising global incidence. …”
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Genome-wide association analysis of composite sleep health scores in 413,904 individuals by Matthew O. Goodman, Tariq Faquih, Valentina Paz, Pavithra Nagarajan, Jacqueline M. Lane, Brian Spitzer, Matthew Maher, Joon Chung, Brian E. Cade, Shaun M. Purcell, Xiaofeng Zhu, Raymond Noordam, Andrew J. K. Phillips, Simon D. Kyle, Kai Spiegelhalder, Michael N. Weedon, Deborah A. Lawlor, Jerome I. Rotter, Kent D. Taylor, Carmen R. Isasi, Tamar Sofer, Hassan S. Dashti, Martin K. Rutter, Susan Redline, Richa Saxena, Heming Wang

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Spatial-temporal baseline study of nutrients and trace elements characterization of a large tropical transition system in West Africa by Celso Paulo, João A. Carreiras, Susanne Tanner, Carmen Van-Dúnem dos Santos, Vanessa F. Fonseca, Bernardo Duarte

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Pengembangan Jadwal Shift Staf Editor Video pada Stasiun Televisi Nasional Trans7 berbasis Android menggunakan Algoritma Ant Colony dengan Firebase by Rizal Rizal, Eliyani Eliyani

“…Tests are carried out on the results of algorithm calculations, functional systems, integration, and feedback to the system by looking for errors on the software interface, and direct use testing to users. …”
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Research on carbon emission accounting model for open-pit mines in alpine ecologically fragile areas by Guoqing LI, Bin BAI, Guiqi LI, Kai GUAN, Jie HOU, Chunping LIN

“…We have developed a carbon emission accounting model that integrates mining production stages with changes in carbon sinks owing to mining-induced disturbances. …”
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Appearance of green tea compounds in plasma following acute green tea consumption is modulated by the gut microbiome in mice by John D. Sterrett, Kevin D. Quinn, Katrina A. Doenges, Nichole M. Nusbacher, Cassandra L. Levens, Mike L. Armstrong, Richard M. Reisdorph, Harry Smith, Laura M. Saba, Kristine A. Kuhn, Catherine A. Lozupone, Nichole A. Reisdorph

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Loss of histone H3K27me3 up-regulates SLC7A11 in diffuse gastric cancer cells by REN Yuanfeng, LIU Wenkang, CHU Zhaole

“…RNA sequencing data， data from high-throughput chromosome conformation capture （Hi-C） technology， and publicly available single-cell data were integrated to investigate the target genes regulated by the reprogramming of H3K27me3 modifications in diffuse gastric cancer cells. …”
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Smartphone-Based Telemonitoring for Better Oral Health With Toothbrushes: 6-Month Randomized Controlled Trial by Jaeyeon Kim, Yiseul Choi, Yoolbin Song, Wonse Park

“… BackgroundA toothbrush device that telemonitors toothbrushing is a technologically advanced solution providing personalized feedback on toothbrushing habits and oral hygiene. These devices integrate smartphone apps to enhance oral health compliance through dental professional feedback. …”
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Injectable Nanocomposite Hydrogel for Accelerating Diabetic Wound Healing Through Inflammatory Microenvironment Regulation by Chen Y, Li Y, Song H, Liu X, Zhang H, Jiang J, Liu H, Zhuo R, Cheng G, Fang J, Xu L, Qi Y, Sun D

“…Employing zeolitic imidazolate framework-8 (ZIF-8) as a drug delivery platform, integrated within a temperature-sensitive injectable hydrogel, presents an intriguing strategy for the closure of various irregular wounds, modulation of inflammatory responses, and promotion of angiogenesis.Methods: Herein, ZIF-8 loaded with curcumin (Cur) combined with methylcellulose/carboxymethyl chitosan (MCC) thermosensitive hydrogel was described. …”
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Study protocol for Adaptive ChemoTherapy for Ovarian cancer (ACTOv): a multicentre phase II randomised controlled trial to evaluate the efficacy of adaptive therapy (AT) with carbo... by Michelle Lockley, Kathy Robinson, Rowan Miller, Charlie Gourley, Nicholas Counsell, Iain Mcneish, Trevor Graham, Uma Anne Mukherjee, Helen Hockings, Apini Patel, Priya Narayanan, Katie Wilkinson, Harjot Dhanda, Alexander R A Anderson

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Migrasi Data Hasil Optimalisasi Pemuatan Kontainer Pada Legacy System ke SAP untuk Mempercepat Pembuatan Surat Jalan dengan Batch Data Communication (BDC) by Rehulina Tarigan, Ely Nuryani, Susy Katarina Sianturi, Nur Hidayanti, Widyawati Widyawati

“…The solution to overcome this problem is to migrate the order data resulting from loading optimization in CSO to SAP so that the order data is integrated with the delivery note data. The BDC method is used to migrate to SAP, namely by transferring order data resulting from loading optimization from CSO to SAP and automating the picking and packing process in SAP to produce delivery note. …”
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Eu:CROPIS AIV Program: Challenges and Solutions for a Spin-Stabilized Satellite Containing Biology by Toni Delovski, Catherin Düvel, Fabian Greif, Ansgar Heidecker, Sebastian Kottmeier, Olaf Mierheim, Falk Nohka, Fabian Orlowski-Feldhusen

“…These payloads and the system design imposed constraints which affected the Assembly Integration and Verification (AIV) program in various ways and created challenges for the relatively small team to find solutions for. …”
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Consecutive prediction of adverse maternal outcomes of preeclampsia, using the PIERS-ML and fullPIERS models: A multicountry prospective observational study. by Guiyou Yang, Tünde Montgomery-Csobán, Wessel Ganzevoort, Sanne J Gordijn, Kimberley Kavanagh, Paul Murray, Laura A Magee, Henk Groen, Peter von Dadelszen

“…Among women whose pregnancies are complicated by preeclampsia, the Preeclampsia Integrated Estimate of RiSk (PIERS) models (i.e., the PIERS Machine Learning [PIERS-ML] model, and the logistic regression-based fullPIERS model) accurately identify individuals at greatest or least risk of adverse maternal outcomes within 48 h following admission. …”
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Comparative efficacy and safety of GLP-1 receptor agonists for weight reduction: A model-based meta-analysis of placebo-controlled trials by Haoyang Guo, Juan Yang, Jihan Huang, Ling Xu, Yinghua Lv, Yexuan Wang, Jiyuan Ren, Yulin Feng, Qingshan Zheng, Lujin Li

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Emodin protects against severe acute pancreatitis-associated acute lung injury by activating Nrf2/HO-1/GPX4 signal and inhibiting ferroptosis in vivo and in vitro by Gang Shen, Haiyun Wen, Huijuan Li, Xuetao Zhang, Bowen Lan, Xuanchi Dong, Peng Ge, Yalan Luo, Hailong Chen

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Establishing a baseline for surgical care in Mongolia: a situational analysis using the six indicators from the Lancet Commission on Global Surgery by Raymond R Price, Ali Jalali, Anudari Zorigtbaatar, Sarnai Erdene, Sergelen Orgoi, Andrea Davis, Jonathan Nellermoe, Jade M Nunez, Simon Ruhnke, Battsetseg Gonchigjav, Nomindari Bat-Erdene, Kevin Bagley, Micah Katz, Hannah Pioli, Batsaikhan Bat-Erdene, Ganbold Lundeg

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Combined biochemical profiling and DNA sequencing in the expanded newborn screening for inherited metabolic diseases: the experience in an Italian reference center by Simona Fecarotta, Lorenzo Vaccaro, Alessandra Verde, Marianna Alagia, Alessandro Rossi, Chiara Colantuono, Maria Teresa Cacciapuoti, Patrizia Annunziata, Sara Riccardo, Antonio Grimaldi, Tonya Fusco, Rosa De Santis, Fernando Barretta, Lucia Albano, Daniela Crisci, Fabiana Vallone, Antonietta Tarallo, Marcella Cesana, Nicola Brunetti-Pierri, Giulia Frisso, Margherita Ruoppolo, Davide Cacchiarelli, Giancarlo Parenti

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On the Subject, Purpose and Method of Religious Education as a Practical Metaphysics by Süleyman Gümüş

“…Its purpose is to demonstrate the process of subjectification integrated with pedagogy by scrutinizing the conditions for the formation of subjectivity. …”
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Analysis of Effective Broodstock Management and Breeding of Patin Siam (Pangasius hypophthalmus) in BBAT Jambi by Mimid A. Hamid, Wahyu B. W, Rangga W, Reni A. Lubis, Atomu Furusawa

“…After collecting all of data in 2006, correlation of productivity with fish size and age were analyzed integrating data. All female were also identified by using PIT tag system and alteration of maturity was monitored monthly, observing development of abdomen, from January to June. …”
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Lachnospiraceae-bacterium alleviates ischemia-reperfusion injury in steatotic donor liver by inhibiting ferroptosis via the Foxo3-Alox15 signaling pathway by Shenghe Deng, Huan Cao, Tongxi Li, Xueling Wang, Junpeng Meng, Teng Zeng, Di Zhang, Shuhua Zhang, Guoliang Wang, Ran Liu, Tianhao Zou, Mao Cai, Ren Lang, Di Lu, Jinyang Gu

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