Differentiation status determines the effects of IFNγ on the expression of PD-L1 and immunomodulatory genes in melanoma by Teitur Sævarsson, Adrián López García de Lomana, Ólafur Sánchez, Veerle van Esch, Gunnar Bjarni Ragnarsson, Siggeir Fannar Brynjólfsson, Eiríkur Steingrímsson, Berglind Ósk Einarsdóttir

“…Interferon-γ (IFNγ) is an integral part of the anti-tumor immune response and can directly induce both differentiational changes and expression of immunosuppressive proteins in melanoma cells. …”
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Investigating the Role of the basic Components of Smart Governance in Realizing a Smart City with the ISM Method (Case Study: Tehran) by ALi Asghar Pourezzat, Tayebeh Abbasi, Shahryar Maghsoodi Kenari, Mohammad Mehdi Namdar Joybari

“…However, the successful implementation of smart city initiatives requires a comprehensive and integrated decision-making framework. The notion of smart governance has thus gained prominence, attracting the attention of scholars across various fields, including public administration, policymaking, political science, and information technology. …”
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Comparison of Secondary Metabolite Extraction Methods in <i>Hamelia patens</i> Jacq. and Their Inhibitory Effect on <i>Fusarium oxysporum</i> f. sp. <i>radicis-lycopersici</i> by Daniel Jafet Valle Ortiz, Dolores Guadalupe Aguila Muñoz, María del Carmen Cruz López, Diana Verónica Cortés Espinosa, Martha Rosales Castro, Fabiola Eloísa Jiménez Montejo

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Retos en la gestión del talento humano: el papel del marketing interno en tiempos desfavorables - Challenges in talent management: The role of internal marketing in adverse times by Francia Contreras García, Tania Elena González Alvarado, Pablo Cabanelas Lorenzo

“…Este estudio ofrece una visión integral de cómo estas variables interactúan y sugiere nuevas líneas de investigación para mejorar la gestión del talento. …”
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Effect of Conductive Education Combined with Exercise Therapy on Rehabilitation Function of Children with Cerebral Palsy by Lihong LI, Liya YANG, Feng HAN, Ningning TIAN, Beibei GONG, Suju CHEN

“…With the deepening of internalization of the external world, children with cerebral palsy can improve their individual mental and emotional level, and ultimately achieve the integrated development of children's condition.…”
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Association between the hemoglobin A1c/High-density lipoprotein cholesterol ratio and stroke incidence: a prospective nationwide cohort study in China by Chaojuan Huang, Hongtao You, Yuyang Zhang, Ligang Fan, Xingliang Feng, Naiyuan Shao

“…The Hemoglobin A1c/High-Density Lipoprotein Cholesterol (HbA1c/HDL-C) ratio, an integrated marker of glycolipid homeostasis, may serve as a novel predictor of stroke risk. …”
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The Prevalence of Dermoscopy Use Among Dermatology Residents in Riyadh, Saudi Arabia: Cross-Sectional Study by Abdullah Almeziny, Rahaf Almutairi, Amal Altamimi, Khloud Alshehri, Latifah Almehaideb, Asem Shadid, Mohammed Al Mashali

“…ObjectiveWe aimed to determine the proportion of dermatology residents in Riyadh who use dermoscopy in their clinical practice; identify factors influencing the use of dermoscopy, such as availability of equipment, training, and the perceived importance of dermoscopy in clinical practice; explore barriers to dermoscopy use, including the lack of access to necessary resources (eg, dermoscopes) and insufficient training; and provide insights into the adoption and integration of dermoscopy into dermatology training and clinical practice in Saudi Arabia. …”
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Racial and ethnic differences in fatal child abuse and neglect and the intersection of community poverty: U.S., 2003 to 2022 by Rebecca F. Wilson, Xin Yue, Karen E. Thomas, Krishna Kiran Kota, Carter J. Betz

“…Participants and methods: This study integrated National Violent Death Reporting System (NVDRS) data, county poverty data, and population estimates data. …”
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Assessment of Asthma Control and Quality of Life among Asthmatic Patients Attending Armed Forces Referral and Teaching Hospital, Addis Ababa, Ethiopia by Tesfalidet Gebremeskel Zeru, Ephrem Engidawork, Alemseged Beyene Berha

“…Healthcare providers should therefore focus on asthma education with an integrated treatment plan to improve asthma control and quality of life.…”
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Long-Term Analysis of Recurrence Beyond Milan Criteria Following Ablation of Solitary Early-Stage Hepatocellular Carcinoma &le;3 cm in Potentially Transplantable Patients: A Over 1... by Chen S, Qi H, Tan H, Cao F, Xie L, Huang T, Wu Y, Wen C, Wang Y, Shen L, Fan W

“…Elevated Platelet-CRP Score(PCS), integrating CRP and PLT, correlated significantly with an increased incidence of RBM and a more aggressive phenotype, characterized by vascular invasion or metastatic dissemination (P< 0.05). …”
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Association and multimodal model of retinal and blood-based biomarkers for detection of preclinical Alzheimer’s disease by Swetha Ravichandran, Peter J. Snyder, Jessica Alber, Charles F. Murchison, Lauren E. Chaby, Andreas Jeromin, Edmund Arthur

“…Conclusions Our analyses show the potential of integrating retinal and blood-based biomarkers for improved detection and screening of preclinical AD.…”
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The Effect of Combining mHealth and Health Professional–Led Intervention for Improving Health-Related Outcomes in Chronic Diseases: Systematic Review and Meta-Analysis by Masashi Kanai, Takahiro Miki, Toshiya Sakoda, Yuta Hagiwara

“…However, the effectiveness of mHealth, particularly when integrated with traditional health care interventions delivered by professionals, warrants comprehensive investigation. …”
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Association between triglyceride-glucose (TyG) related indices and cardiovascular diseases and mortality among individuals with metabolic dysfunction-associated steatotic liver dis... by Yanan Qiao, Yue Wang, Cheng Chen, Yueqing Huang, Chunhua Zhao

“…Additionally, Harrell’s C-index, net reclassification index (NRI), and integrated discrimination improvement index (IDI) were used to assess the predictive performance of these indices. …”
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Electroacupuncture alleviates functional constipation by upregulating host-derived miR-205-5p to modulate gut microbiota and tryptophan metabolism by Lu Wang, Lu Wang, Menghan Xi, Menghan Xi, Wei Cao, Haiyan Qin, Di Qin, Shuai Chen, Siyuan Zhou, Yujun Hou, Ying Chen, Xianjun Xiao, Qianhua Zheng, Dehua Li, Ying Li

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Effect of Suspension Massage Exercise Technique on Core Muscle Mass and Postural Control Ability of Patients with Stroke by SUN Jie, CHEN Guijuan, XU Han, ZHANG Tianyu, DING Yi, WANG Shurui, LI Li

“…Surface electromyography (sEMG) was used to measure the median frequency (MF) and integrated electromyography (iEMG) of the patients' bilateral erector spinae and multifissure muscles.ResultsBefore treatment, there was no statistically significant difference in PASS, BBS, FMA-LE, MBI scores, or bilateral erector spinae and multifidus MF and iEMG values between the two groups (<italic>P</italic>&gt;0.05). …”
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Species evolution: cryptic species and phenotypic noise with a particular focus on fungal systematics by Anusha H. Ekanayaka, Anusha H. Ekanayaka, Samantha C. Karunarathna, Samantha C. Karunarathna, Saowaluck Tibpromma, Arun Kumar Dutta, Danushka Sandaruwan Tennakoon, Anuruddha Karunarathna, Ekachai Chukeatirote, Dong-Qin Dai, Steven L. Stephenson, Sajeewa S. N. Maharachchikumbura, Chao Liu, Alan J. L. Phillips

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Implementation of Compensation-Sensitive Shot-Style-Feedback of Aiming Point Training Data at the Swiss Shooting Federation by Dino Tartaruga, Ralf Kredel

“…Discussion/Conclusion The integration of compensation-sensitive shot-styles and the consideration of individual preferences have led to a higher acceptance of the tailored feedback reports than the previous more generalised reports. …”
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The Efficacy of Moxibustion on the Serum Levels of CXCL1 and β-EP in Patients with Rheumatoid Arthritis by Siyu Tao, Xue Wang, Chenxi Liao, Yan Xiong, Jie Tang, Nannan Jiang, Yuan Li, Xinyue Hu, Rouxian Shuai, Yueyue Wang, Ping Wu

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Impact of cariprazine on body weight and blood pressure among adults with bipolar I disorder, schizophrenia, or major depressive disorder in a real-world setting by Christoph U. Correll, Andrew J. Cutler, François Laliberté, Guillaume Germain, Sean D. MacKnight, Julien Boudreau, Sally W. Wade, Nadia Nabulsi, Huy-Binh Nguyen, Mousam Parikh

“…Methods Symphony Health’s Integrated Dataverse® with electronic medical record access (3/1/2015–10/31/2018) was used to identify adults (≥ 18 years) diagnosed with BP-I depression, BP-I mania/mixed, schizophrenia, or MDD, with ≥ 2 cariprazine dispensings (first dispensing = index) and continuous clinical activity for ≥ 12 months pre-index (baseline) and ≥ 3 months post-index. …”
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ViTAU: Facial paralysis recognition and analysis based on vision transformer and facial action units by Jia GAO, Wenhao CAI, Junli ZHAO, Fuqing DUAN

“…Our proposed method integrates ViT with facial AUs, designing a ViT-based facial paralysis recognition network that enhances the extraction of local area features through its self-attention mechanism, thereby enabling precise recognition of facial paralysis. …”
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