Unveiling the ultimate advantage: a meta-analysis of 3D visualization and problem-based learning in orthopedic education by Ting Li, Yidan Hu, Ruohong Song, Hangyu Liu, Xin Gao, Fei Wang, Chengwei Xiao, Xilin Liu

“…However, there is a conspicuous lack of systematic reviews that thoroughly evaluate both the advantages and drawbacks of integrating 3D with problem-based learning (3D + PBL). …”
Get full text

Nomograms for predicting recurrence of HER2‐positive breast cancer with different HR status based on ultrasound and clinicopathological characteristics by Xudong Zhang, Hanqing Kong, Xiaoxue Liu, Qingxiang Li, Xinran Fang, Junjia Wang, Zihao Qin, Nana Hu, Jiawei Tian, Hao Cui, Lei Zhang

“…Conclusions Ultrasound performance of HER2+ breast cancers with different HR status was significantly different. Nomograms integrating ultrasound and clinicopathological characteristics exhibited favorable performance and have the potential to serve as a reliable method for predicting recurrence in heterogeneous breast cancer.…”
Get full text

Spatiotemporal variability of groundwater chemistry, source identification and health risks in the southern Chinese Loess Plateau by Zijun Li, Qingchun Yang, Chuan Xie, Hongyun Ma, Bin Wu, Yanli Wang

“…The results showed that except for bicarbonate, spatiotemporal variability of hydrochemical components in Malian River Basin (ML) was generally greater than that in Upper Jinghe River basin (JH-U) due to the hydrogeological conditions, and the hydrochemical facies in two river basins transformed from SO4·Cl and Cl·SO4 types to HCO3 and HCO3·SO4 types. The results of integrated-weight quality index (IWQI) showed that 77.8 % (1970s), 33.3 % (2004), 34.3 % (2015) of samples in ML exceeded the standard limits of Class IV groundwater quality, displaying a high pollution level with an improvement trend, while groundwater quality in JH-U indicated a very low pollution level with a deterioration trend. …”
Get full text

Evaluation of Machine Learning Models for Stress Symptom Classification of Cucumber Seedlings Grown in a Controlled Environment by Kyu-Ho Lee, Samsuzzaman, Md Nasim Reza, Sumaiya Islam, Shahriar Ahmed, Yeon Jin Cho, Dong Hee Noh, Sun-Ok Chung

“…A cost-effective RGB camera, integrated with a microcontroller, captured images from the top of the seedlings over a two-week period, from which sequential forward floating selection (SFFS) and correlation matrices were used to streamline feature extraction. …”
Get full text

Protocol for a feasibility study and process evaluation of a psychosocially modelled diabetes education programme for young people with type 1 diabetes: the Youth Empowerment Skill... by Nick Sevdalis, Khalida Ismail, Tayana Soukup, Trevor Murrells, Dulmini Kariyawasam, Stephen Thomas, Judith Parsons, Angus Forbes, Rita Forde, Maria Baldellou Lopez, Marie Jones, Martha Ford-Adams, Nardos Yemane, Siobhan Pender, Alex Silverstien

“…We will conduct a feasibility randomised controlled trial (waiting-list design) with integrated process evaluation. Fifty young people with type 1 diabetes (aged 14–19 years) will be randomly allocated to either the YES intervention or a waiting-list control. …”
Get full text

Policy and practice implication of - and tools to address - mental health and psychosocial support needs in Sierra Leone by Alastair Ager, Rebecca Horn, Abdulai Bah, Abdulai Bah, Haja Wurie, Mohamed Samai, Mohamed Samai

“…In terms of policy, findings reinforce key principles regarding community-based provision, integration of mental health care into primary health care, and actions to reduce stigma associated with mental health.…”
Get full text

Effective Facial Expression Recognition System Using Artificial Intelligence Technique by Imad S. Yousif, Tarik A. Rashid, Ahmed S. Shamsaldin, Sabat A. Abdulhameed, Abdulhady Abas Abdullah

“…Importantly, results on the study show that this integrated model has a large-scale promoting effect in emotion detection upon varied scenes and is therefore generalizable to many domains from security and surveillance over biomedicine up to interactive AI-driven systems. …”
Get full text

Post‐operative incidence of lymphedema after RARP with or without extended pelvic lymph node dissection in a cohort study by Andries Clinckaert, Laura Ysenbaardt, Annabel Bijnens, Charlotte Van Calster, Inge Geraerts, Steven Joniau, Nele Devoogdt, Luc Bijnens, Wouter Everaerts

“…Structured electronic case report forms (eCRFs) integrated into the electronic health record system were used to document intraoperative, perioperative and postoperative data. …”
Get full text

Transcriptome and Metabolome Analysis Unveil Anthocyanin Metabolism in Pink and Red Testa of Peanut (Arachis hypogaea L.) by Qiqin Xue, Xiurong Zhang, Hui Yang, Huadong Li, Yuying Lv, Kun Zhang, Yongguang Liu, Fengzhen Liu, Yongshan Wan

“…These differentially expressed genes were significantly enriched in the flavonoid biosynthesis, biosynthesis of secondary metabolites, and metabolic pathways. Integrated analysis of transcriptome and metabolome indicated CHS gene (arahy.CM90T6), F3′H genes (arahy. 8F7PE4 and arahy. …”
Get full text

Spartina alterniflora invasion significantly alters the assembly and structure of soil bacterial communities in the Yellow River Delta by Pengyuan Sun, Yuxin Wu, Pengcheng Zhu, Jingfeng Wang, Jingfeng Wang, Xiaona Yu, Weihua Guo

“…Soil microbial communities are integral to almost all terrestrial biogeochemical cycles, which are essential to coastal wetland functioning. …”
Get full text

Understanding the educational inequalities in suicide attempts and their mediators: a Mendelian randomisation study by Jing Wang, Ye Yang, Rui Gao, Lilu Ding, Jiahao Zhu, Dan Zhou, Yingjun Li, Houpu Liu

“…Elucidating modifiable risk factors that serve as intermediaries in the impact of low educational attainment on suicide has the potential to reduce health disparities.Aims To examine the risk factors that mediate the relationship between educational attainment and suicide attempts and quantify their contributions to the mediation effect.Methods We conducted a two-sample Mendelian randomisation (MR) analysis to estimate the causal effect of educational attainment on suicide attempts, utilising genome-wide association study summary statistics from the Integrative Psychiatric Research (iPSYCH; 6024 cases and 44 240 controls) and FinnGen (8978 cases and 368 299 controls). …”
Get full text

Metabolic Profiling by UPLC–Orbitrap–MS/MS of Liver from C57BL/6 Mice with DSS-Induced Inflammatory Bowel Disease by Zhongquan Xin, Zhenya Zhai, Hongrong Long, Fan Zhang, Xiaojun Ni, Jinping Deng, Lunzhao Yi, Baichuan Deng

“…Notably, 133 metabolites were identified by an integrated database. Metabolism network and pathway analyses demonstrated that the metabolic disturbance of the liver in IBD mice was mainly enriched in bile acid metabolism, arachidonic acid metabolism, amino acid metabolism, and steroid hormone biosynthesis, while those disturbances were regulated or reversed through cecropin A and antibiotic treatment. …”
Get full text

Association between triglyceride glucose index and adverse cardiovascular prognosis in patients with atrial fibrillation without diabetes: a retrospective cohort study by Aobo Gong, Ying Cao, Zexi Li, Wentao Li, Fanghui Li, Yao Tong, Xianjin Hu, Rui Zeng

“…Conclusions A high Tyg index is associated with poorer prognosis in patients with AF without diabetes. Integrating the Tyg index into the CHA2DS2-VASc model may enhance its predictive performance, offering clinical utility.…”
Get full text

Evaluation of two electronic-rehabilitation programmes for persistent knee pain: protocol for a randomised feasibility trial by Philip G Conaghan, Kim L Bennell, Mark Conner, Rana S Hinman, Sarah R Kingsbury, Elizabeth M A Hensor, Gretl A McHugh, Christine Comer, Dawn Groves-Williams, Rachel K Nelligan

“…Feasibility variables, patient-reported outcomes and clinical findings measured at baseline, 3 and 9 months will be assessed and integrated with qualitative interview data from a subset of Group E-Rehab and My Knee UK participants. …”
Get full text

Temporally enhanced RSEI and nighttime lights reveal long-term ecological changes and effective protection in China’s inaugural national parks by Chunhui Wen, Tengfei Long, Guojin He, Weili Jiao, Wei Jiang

“…The results indicate that: 1) The temporally enhanced RSEI (tRSEI) effectively integrates the dynamic changes of multiple variables and offers better temporal comparability for long-term ecological monitoring; 2) From 2000 to 2022, the ecological environment quality within the inaugural NPs significantly improved, with more noticeable improvements observed following the implementation of pilot conservation programs; 3) The spatial variation in ecological quality within these NPs is driven by the interaction of multiple factors, including human activities, climate variability, and topographical conditions, with significant differences among the parks; 4) Although overall NTL intensity both inside and outside the NPs increased between 2000 and 2022, especially with accelerated growth in surrounding areas post-pilot program implementation, NTL levels within the parks remained relatively low. …”
Get full text

Hierarchizing multi-scale environmental effects on agricultural pest population dynamics: a case study on the annual onset of Bactrocera dorsalis population growth in Senegalese or... by Caumette, Cécile, Diatta, Paterne, Piry, Sylvain, Chapuis, Marie-Pierre, Faye, Emile, Sigrist, Fabio, Martin, Olivier, Papaïx, Julien, Brévault, Thierry, Berthier, Karine

“…Implementing integrated pest management programs to limit agricultural pest damage requires an understanding of the interactions between the environmental variability and population demographic processes. …”
Get full text

A comparative study between condensed polytetrafluoroethylene mesh versus other composite meshes in Endo-laparoscopic ventral herniorrhaphy by Meredeth Chin, James Lee Wai Kit, Sujith Wijerathne, Avelyn Aw, Daryl Chia Kai Ann, Sean Lee Kien Fatt, Tharun Ragupathi, Harry Ng Ho Man, Davide Lomanto

“…A new generation of monolayer condensed polytetrafluoroethylene (cPTFE) Omyra® mesh, which theoretically has better tissue integration with parietal tissue and possibly lesser adhesions with visceral organs is now available for use. …”
Get full text

Model-Based Variation-Aware Optimization for Offset Calibration and Pre-Sensing in DRAM Sense Amplifiers by Dongyeong Kim, Geon Kim, Suyeon Kim, Jewon Park, Sinwook Kim, Hyeona Seo, Chaehyuk Lim, Sowon Kim, Juwon Lee, Jeonghyeon Yun, Hyerin Lee, Jinseok Park, Yongbok Lee, Seungchan Lee, Myoungjin Lee

“…Notably, our model incorporates <inline-formula> <tex-math notation="LaTeX">$t_{OC}$ </tex-math></inline-formula> dependency, which was not considered in previous models, and accurately analyzes transistor size effects through integration with Pelgrom&#x2019;s equation. The primary advantage of the proposed model lies in its design optimization efficiency. …”
Get full text

Understanding stakeholder views of the use of digital therapeutic interventions within children and young people’s mental health services by Brioney Gee, Brioney Gee, Tim Clarke, Tim Clarke, Jess Garner, Bonnie Teague, Bonnie Teague, Georgianna Coote, Aoife Dunne, Rachel McGuire, Andrew Laphan, Manjul Rathee, Jon Wilson, Jon Wilson

“…Actions perceived to facilitate more effective implementation included: a) co-producing interventions, commissioning decisions and implementation plans with children and parents/carers, b) enhancing national guidance and local leadership, c) integration of digital offers within existing clinical pathways, and d) efforts to ensure accessibility and inclusivity.DiscussionDigital therapeutic interventions offer a promising solution to the challenge of improving access to mental health support for children and young people. …”
Get full text

Waterbird diversity and its influencing factors in various types of coastal wetlands in the Bohai Rim region by Mengdi FU, Jun WANG, Chunfei HOU, Junsheng LI, Jiade BAI, Yuanyuan ZHANG

“…This study provides important insights into how air pollution, water pollution, and climate change affect waterbird diversity, emphasizing the importance of integrated management strategies for maintaining coastal wetland ecosystem stability and the health of waterbird communities.…”
Get full text