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20741
Failure and development height of overlying rock of a water flowing fracture in goaf under a karst aquifer
Published 2025-01-01“…Four key strata were identified, and their fracture steps were calculated through integrating the results of the physical test of the overlying rock of the coal seam. …”
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20742
Research progress and perspectives on the application of tyramide signal amplification-based multiplex immunohistochemistry/immunofluorescence: a bibliometrics analysis
Published 2025-01-01“…The University of Texas System (53, 6.07%) was the most productive institution. Integrating these results of hotspot and frontier analysis, TSA-based mIHC/IF provides significant benefits, particularly in neurology, cancer and immunology.ConclusionThis study conducted a comprehensive bibliometric analysis for the use of TSA-based mIHC/IF. …”
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20743
The impact of dimethylaminohexadecyl methacrylates on the physical and antibacterial properties of endodontic sealers
Published 2025-01-01“….% DMAHDM, while the AH Plus control sealers were covered with a thick layer of biofilms.ConclusionsThe results of this study suggest that DMAHDM, as a contact-killing agent, could be used as an approach to prevent endodontic reinfections.Clinical RelevanceIntegrating DMAHDM into commercial sealers may enhance their antibacterial properties. …”
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20744
Exploring the Landscape of Programming Language Identification With Machine Learning Approaches
Published 2025-01-01“…The increasing complexity of modern software development necessitates tools and methodologies for code analysis, maintenance, and migration in multi-language Integrated Development Environments (IDEs). The security needs of the software development process also recently led to the introduction of the Software Bill of Materials (SBOM), which vendors must include in their products. …”
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20745
Evaluation of a pragmatic approach to predicting COVID-19-positive hospital bed occupancy
Published 2025-02-01“…Evaluation data covered individuals registered with a general practitioner in North West London, through the Whole Systems Integrated Care deidentified dataset. We extracted data on COVID-19-positive tests, vaccination records and admissions to hospitals with confirmed COVID-19 within the study period. …”
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20746
Model Construction of InSAR-based Rainfall Thresholds for Landslide Hazards in Yanhe Basin, Chinese Loess Plateau
Published 2024-12-01“…[Methods] Taking the Yanhe River Basin on the Loess Plateau as the research area, the landslide identification of the Yanhe River Basin based on InSAR was carried out by integrating Sentinel-1A, DEM, GPM rainfall and other multi-source data. …”
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20747
Bridging Needs and Expectations of Individuals With Physical Disabilities and Community Services Stakeholders for the Cocreation of an Adapted Physical Activity Platform in Virtual...
Published 2025-01-01“…ConclusionsBy exploring the needs and expectations regarding VR technology from individuals with physical disabilities and their interventionists, this study provided essential insights for integrating immersive and nonimmersive VR into community organizations, informing next steps for the design of adapted physical activities in VR.…”
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20748
Abdominal fat distribution and its relationship to brain changes: the differential effects of age on cerebellar structure and function: a cross-sectional, exploratory study
Published 2013-01-01“…Moreover, we aimed to investigate whether these effects change with age.Design Cross-sectional, exploratory.Setting University Clinic, Integrative Research and Treatment Centre.Participants We included 100 (mean BMI=26.0 kg/m², 42 women) out of 202 volunteers randomly invited by the city's registration office, subdivided into two age groups: young-to-mid-age (n=51, 20–45 years of age, mean BMI=24.9, 24 women) versus old (n=49, 65–70 years of age, mean BMI=27.0, 18 women).Main outcome measures VAT, BMI, subcutaneous abdominal adipose tissue, brain structure (grey matter density), functional brain architecture (eigenvector centrality, EC).Results We discovered a loss of cerebellar structure with increasing VAT in the younger participants, most significantly in regions involved in motor processing. …”
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20749
Inflammatory-Driven Angiogenesis in Bone Augmentation with Bovine Hydroxyapatite, B-Tricalcium Phosphate, and Bioglasses: A Comparative Study
Published 2018-01-01“…The purpose of this study was to analyse the ability to integrate bone substitutes by evaluating the immunohistochemical expression of the platelet endothelial cell adhesion molecules, vascular endothelial growth factor, collagen IV, laminin, and osteonectin, in the vicinity of bone grafts, enabling tissue revascularization and appearance of bone lamellae. …”
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20750
Optimization of Toxicity, Biodegradability, and Skin Irritation in Formulations Containing Mixtures of Anionic and Nonionic Surfactants Combined with Silica Nanoparticles
Published 2025-01-01“…Overall, the findings emphasize the need for careful selection of surfactant mixtures and nanoparticle integration to minimize environmental toxicity and potential skin irritation and increase their biodegradability.…”
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20751
Multicentre, prospective, randomised controlled trial to evaluate hexaminolevulinate photodynamic therapy (Cevira) as a novel treatment in patients with high-grade squamous intraep...
Published 2022-06-01“…APRICITY is a multicentre, prospective, double-blind, randomised controlled phase 3 study further evaluating the efficacy and safety of Cevira, an integrated drug-delivery and light-delivery device for hexaminolevulinate photodynamic therapy, which shows promise as a novel, non-invasive outpatient therapy for women with HSIL.Methods and analysis Patients with biopsy-confirmed HSIL histology are invited to participate in the study planned to be conducted at 47 sites in China and 25 sites in Ukraine, Russia and the European Union. …”
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20752
Evaluating the Accessibility of Urban Public Open Spaces Based on an Improved 2SFCA Model: A Case Study Within Chengdu’s Second Ring Road
Published 2025-01-01“…This study, taking the area within Chengdu’s Second Ring Road as an example, proposes a 2SFCA model that integrates both supply and demand improvements to evaluate UPOS accessibility. …”
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20753
The Application of Numerical Simulation in Debris Flow Disaster Early Warning: A Case Study of Shiyang Gully, China
Published 2025-01-01“…This study demonstrates the value of numerical simulation in refining early warning systems by integrating multi-scenario analyses of rainfall parameters. …”
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20754
Caution when using network partners for target identification in drug discovery
Published 2025-04-01“…We used the IntAct database to find physically interacting proteins of genes identified by exome-wide association studies (ExWASs), genome-wide association studies (GWASs) combined with a locus-to-gene mapping algorithm called the Effector Index, and Genetic Priority Score (GPS), which integrated eight genetic features with drug indications from the Open Targets and SIDER databases. …”
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20755
Dissecting macrophage heterogeneity and kaempferol in lung adenocarcinoma: a single-cell transcriptomic approach and network pharmacology
Published 2025-01-01“…These findings underscore the translational potential of integrating TCM-derived compounds into immunotherapeutic strategies for LUAD.…”
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20756
Radiomics analysis of thoracic vertebral bone marrow microenvironment changes before bone metastasis of breast cancer based on chest CT
Published 2025-02-01“…Multiple machine learning algorithms were utilized to construct various radiomics models for predicting the risk of bone metastasis, and the model with optimal performance was integrated with clinical features to develop a nomogram. …”
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20757
How I experienced tele-intervention: Qualitative insights from persons who stutter
Published 2025-01-01“…Tele-intervention should be integrated into a hybrid intervention model that PWS prefer.…”
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20758
Advancing Building and Construction Higher Education: The Online Real-Time Block Model’s Contributions to Professional Skills, Gender Equity, and Industry Preparedness
Published 2025-01-01“…Findings, derived from SEU and QILT, reveal that ORT-BM improves student satisfaction, accelerates course completion rates, and fosters gender equity through inclusive learning environments while enhancing accessibility for geographically dispersed and disadvantaged students. By integrating advanced digital tools like virtual site visits, ORT-BM enhances professional readiness, aligning education with evolving industry standards. …”
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20759
Evaluation of urban water cycle health status based on DPSIRM framework and AHP-FCE-Cloud model
Published 2025-01-01“…This study employs the Driving force-Pressure-State-Impact-Response-Management (DPSIRM) framework, using key policy implementation milestones as benchmarks to divide the timeline into three evaluation phases, thereby optimizing the urban water cycle health evaluation system. By integrating the Cloud model with the Analytic Hierarchy Process-Fuzzy Comprehensive Evaluation (AHP-FCE) model, an improved AHP-FCE-Cloud model is constructed. …”
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20760
Tropical cyclone intensity estimation based on YOLO-NAS using satellite images in real time
Published 2025-02-01“…The meteorological significance of this work lies in its ability to offer a reliable, real-time tool for cyclone intensity prediction, which could be integrated into operational weather forecasting systems. …”
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