PINK1 modulates Prdx2 to reduce lipotoxicity‐induced apoptosis and attenuate cardiac dysfunction in heart failure mice with a preserved ejection fraction by Hao Zhang, Tianyu Xu, Xiyuan Mei, Qiming Zhao, Qiling Yang, Xianghui Zeng, Zhuang Ma, Haobin Zhou, Qingchun Zeng, Dingli Xu, Hao Ren

“…Our studies offer valuable insights, opening avenues for the development of innovative therapeutic strategies in the prevention and treatment of HFpEF.…”
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Deciphering the functional roles of PE18 and PPE26 proteins in modulating Mycobacterium tuberculosis pathogenesis and immune response by Aquib Ehtram, Mohd Shariq, Neha Quadir, Neha Quadir, Salma Jamal, Manjunath Pichipalli, Sheeba Zarin, Sheeba Zarin, Javaid Ahmad Sheikh, Nasreen Z. Ehtesham, Seyed E. Hasnain, Seyed E. Hasnain

“…Further studies focusing on their structure-function relationships and interactions with host proteins could accelerate the development of innovative therapeutic strategies.…”
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Impact of a new case-based payment scheme on volume distribution across public hospitals in Zhejiang, China: does ‘Same disease, same price’ matter by Meiteng Yu, Jing Liu, Tao Zhang

“…Abstract Background With the implementation of the hierarchical medical system (HMS) in China, Zhejiang Province introduced an innovative payment scheme called “payment method by disease types with point counting”. …”
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Assessment of Learning Styles of First-year Medical Students’ using VARK 8.02 Model Questionnaire: A Cross-sectional Study by Senthil Ganesh P Kannappan, Ravichandran Doraisamy, Vijayakumar Jagadesan

“…Introduction: Students are constantly in search of additional and innovative ways to stimulate their attention in learning various subjects. …”
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A web-based pilot randomized controlled trial to test the efficacy of education and contact-based interventions in reducing public suicide stigma by Nathalie Oexle, Matthias Lühr, Daniele Valacchi, Nicolas Rüsch

“…Future research should explore innovative and safe approaches to reduce public suicide stigma. …”
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Billing models for measuring nursing care in inpatient and outpatient settings: a scoping review by Marco Di Nitto, Francesca Napolitano, Michela Calzolari, Yari Longobucco, Vittorio Masotta, Francesco Zaghini, Rosaria Alvaro, Giancarlo Cicolini, Loreto Lancia, Duilio Fiorenzo Manara, Laura Rasero, Gennaro Rocco, Maurizio Zega, Beatrice Mazzoleni, Loredana Sasso, Annamaria Bagnasco

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A Retroperitoneal Isolated Enteric Duplication Cyst Mimicking a Teratoma: A Case Report and Literature Review by Daichi Momosaka, Yasuhiro Ushijima, Akihiro Nishie, Yoshiki Asayama, Kousei Ishigami, Yukihisa Takayama, Daisuke Okamoto, Nobuhiro Fujita, Tetsuo Ikeda, Keiichiro Uchida, Masaaki Sugimoto, Kenichi Kohashi, Hiroshi Honda

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Superconducting Nanostrip Photon-Number-Resolving Detector as an Unbiased Random Number Generator by Pasquale Ercolano, Mikkel Ejrnaes, Ciro Bruscino, Syed Muhammad Junaid Bukhari, Daniela Salvoni, Chengjun Zhang, Jia Huang, Hao Li, Lixing You, Loredana Parlato, Giovanni Piero Pepe

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Surrogate-based model parameter optimization in simulations of the West African monsoon by M. Fischer, P. Knippertz, C. Proppe

“…Building upon our previous work utilizing the ICON (icosahedral nonhydrostatic) numerical model to construct statistical surrogate models for quantities of interest (QoIs) characterizing the WAM, this paper focuses on the optimization of the three uncertain model parameters of entrainment rate, fall speed of ice, and soil moisture evaporation fraction through innovative multi-objective optimization (MOO) techniques. …”
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Widely Targeted Metabolomics Analysis Reveals Key Quality-Related Metabolites in Kernels of Sweet Corn by Ruichun Yang, Yunfeng Li, Yuanyuan Zhang, Jun Huang, Junjie Liu, Zimei Lin, Qinqin Yu, Aimin Wu, Bo Wang

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Association between weight-adjusted waist-index and symptoms of sleep apnea in US adults: results from 2015–2018 national health and nutrition examination survey by Edmore Madondo, Paddington T. Mundagowa, Ayesha Mukhopadhyay, Debra Bartelli, Yu Jiang, Fawaz Mzayek

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Mutations in the ARAP3 Gene in Three Families with Primary Lymphedema Negative for Mutations in Known Lymphedema-Associated Genes by Maurizio Ricci, Rita Compagna, Bruno Amato, Sercan Kenanoglu, Dominika Veselenyiova, Danjela Kurti, Mirko Baglivo, Syed Hussain Basha, Roberta Serrani, Giacinto Abele Donato Miggiano, Barbara Aquilanti, Giuseppina Matera, Giuseppe Marceddu, Valeria Velluti, Lucilla Gagliardi, Munis Dundar, Juraj Krajcovic, Matteo Bertelli

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Prevalence and mortality trends of hemoglobinopathies in Italy: a nationwide study by Barbara Gianesin, Frédéric B. Piel, Khaled M. Musallam, Susanna Barella, Maddalena Casale, Elena Cassinerio, Rosario Di Maggio, Antonia Gigante, Maria Rita Gamberini, Giovanna Graziadei, Roberto Lisi, Filomena Longo, Aurelio Maggio, Raffaella Origa, Annamaria Pasanisi, Silverio Perrotta, Antonio Giulio Piga, Valeria Maria Pinto, Rosamaria Rosso, Giacomo Robello, Giovanna Russo, Marco Zecca, Lucia De Franceschi, Gian Luca Forni, Italian Hemoglobinopathies National Survey Group

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Development of Stylistics and Rhetoric in Lithuania by Irena Smetonienė, Marius Smetona

“…The established understanding within the rhetoric canon is being disrupted, and new rules and traditions are taking shape. These innovations are noted to initially emerge in the USA, then spread to Europe, eventually reaching Lithuania. …”
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Omentin-1, a Protective Adipokine for Irritable Bowel Syndrome by Gao Y, Chen C, Huang X, Liu Y, Zhou Z, Pan Y

“…Supplement of omentin-1 was protective against visceral hypersensitivity and mucosal inflammation in an IBS mouse model.Discussion: Our findings highlight the potential value of serum omentin-1 levels as an innovative biomarker in IBS, emphasizing its significance in improving clinical treatment and management of the disease.Keywords: irritable bowel syndrome, adipokine, omentin-1, clinical symptoms, quality of life, psychological symptoms…”
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Le flirt à Rabat au Maroc : Engagements des corps et arrangements socio-spatiaux by Chadia Arab, Christophe Guibert

“…The article shows that young women and men innovate in terms of strategies for living out their expressions of intimacy through what we have called “geographical bubble”. …”
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Evaluation of an Interdisciplinary Educational Program to Foster Learning Health Systems: Education Evaluation by Sathana Dushyanthen, Nadia Izzati Zamri, Wendy Chapman, Daniel Capurro, Kayley Lyons

“…However, there is a lack of an appropriately skilled interprofessional informatics workforce that can leverage knowledge to design innovative solutions. Therefore, there is a need to develop tailored professional development training in digital health, to foster skilled interprofessional learning communities in the health care workforce in Australia. …”
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The structural characteristics of dietary fibers from Tremella fuciformis and their hypolipidemic effects in mice by Shanshan Zhang, Xinle Xu, Xu Cao, Tingting Liu

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Modeling Coupled Nonlinear Multilayered Dynamics: Cyber Attack and Disruption of an Electric Grid by Marc Mangel, Jimmie McEver

“…We conclude by discussing the innovative aspects of our methods, which include (i) a fraction of decoy components in the cyber system, which are not connected to the rest of the cyber system or the physical system and thus do not spread compromise but increase the probability of detection of compromise, (ii) allowing components of the cyber system to return to the un-compromised state either temporarily invulnerable or immediately vulnerable, (iii) adaptive Defensive Counter Measures that respond in a nonlinear fashion to attack and compromise (in analogy to killer T cells of the immune system), (iv) a generic metric of performance of the physical system that depends upon the state of the cyber system, and (v) coupling a model of the electric grid to the model of compromise of the cyber system that leads to a condition for failure of the grid in terms of parameters of both compromise and the synchronous motor model, directions for future investigations, and connections to recent studies on broadly the same topics. …”
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Surfaces environmental monitoring of SARS-CoV-2: Loop mediated isothermal amplification (LAMP) and droplet digital PCR (ddPCR) in comparison with standard Reverse-Transcription qua... by Simona Spiteri, Irene Salamon, Luna Girolamini, Maria Rosaria Pascale, Federica Marino, Carlo Derelitto, Laura Caligaris, Simone Paghera, Manuela Ferracin, Sandra Cristino

“…Although the RT-LAMP requires improvements in term of SE and SP, this research presents an innovative environmental monitoring and prevention method for SARS-CoV-2, that could be extended to other pathogens that are under environmental surveillance.…”
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