Global Fluoroquinolone Resistance Epidemiology and Implictions for Clinical Use by Axel Dalhoff

“…Global surveillance studies demonstrate that fluoroquinolone resistance rates increased in the past years in almost all bacterial species except S. pneumoniae and H. influenzae, causing community-acquired respiratory tract infections. …”
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Bacterial Infection Complicating Varicella Infection: A 10-Year Review of Hospitalized Children by Golda Milo-Manson, Carol Portwine, Elaine Wang

“…GAS was the most frequent isolate in the cases, followed by Staphylococcus aureus, Escherichia coli and Haemophilus influenzae. The types of infection were significantly different for GAS compared with other organisms, with a predominance of skin infections in the former group (χ2 analysis, P<0.05). …”
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Nasopharyngeal Bacterial Carriage in the Conjugate Vaccine Era with a Focus on Pneumococci by V. T. Devine, J. M. Jefferies, S. C. Clarke, S. N. Faust

“…It has been shown that, following PCV7 introduction, an eradication of pneumococcal vaccine types has resulted in increases in the abundance of other respiratory pathogens including Haemophilus influenzae and Staphylococcus aureus. These changes are difficult to attribute to PCV7 introduction alone and these studies do not account for further changes due to PCV13 implementation. …”
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Hib Vaccines: Past, Present, and Future Perspectives by Adi Essam Zarei, Hussein A. Almehdar, Elrashdy M. Redwan

“…Haemophilus influenzae type b (Hib) causes many severe diseases, including epiglottitis, pneumonia, sepsis, and meningitis. …”
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Bacterial Culture of Tear Duct Infections Secondary to Congenital Nasolacrimal Duct Obstructions by Weiming Yang, Li Shen, Anken Wang, Meiyan Li, Chenhao Yang

“…The most prevalent Gram-negative bacteria were Neisseria (nonpathogenic) (25 isolates, 11.2%), followed by Escherichia coli (16 isolates, 7.2%) and Haemophilus influenzae (16 eyes, 7.2%). Antibiotic susceptibility test results suggested that both Gram-positive and Gram-negative bacteria were highly sensitive to most of the tested antibiotics. …”
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Gradenigo’s Syndrome and Bacterial Meningitis in a Patient with a Petrous Apex Cholesterol Granuloma by Jacqueline Hodges, Julie Matsumoto, Nicholas Jaeger, Brian Wispelwey

“…He was diagnosed with bacterial meningitis by lumbar puncture and treated with empiric antibiotics, with CSF eventually revealing nontypeable Haemophilus influenzae. Several days into his course, he developed diplopia with leftward gaze. …”
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Detection of Eight Respiratory Bacterial Pathogens Based on Multiplex Real-Time PCR with Fluorescence Melting Curve Analysis by Liuyang Hu, Bing Han, Qin Tong, Hui xiao, Donglin Cao

“…Acinetobacter baumannii, Escherichia coli, Klebsiella pneumoniae, Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus, Pseudomonas aeruginosa, and Mycobacterium tuberculosis are primary respiratory bacterial pathogens contributing to morbidity and mortality in developing countries. …”
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Modeling and simulation of distribution and drug resistance of major pathogens in patients with respiratory system infections by Li Yang, Ermin Liang, Yali Gao

“…Results The most common pathogens were Streptococcus pneumoniae (30%), Haemophilus influenzae (20%), Pseudomonas aeruginosa (15%), Staphylococcus aureus (10%) and Klebsiella pneumoniae (10%). …”
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Distinct relative abundances in pathogens detected in mechanically ventilated patients with suspected pneumonia in the intensive care unit at King Abdulaziz University Hospital by Haifa Algethamy, Diyaa H. Bokhary, Ibrahim Abushoshah, Abdulrahman A. Alalyani, Maan K. Baamer, Dalya M. Attallah, Ruba M. Alotaibi, Shehla N. Amin, Shaza A. Mass, Nisreen R. Tashkandy

“…In order, the ten most common species detected in 16 clusters were Klebsiella pneumoniae, Stenotrophomonas maltophilia, Haemophilus influenzae, Pseudomonas aeruginosa, Metamycoplasma salivarium, Elizabethkingia anophilis, Staphylococcus aureus, Acinetobacter baumannii, Prevotella oris and Klebsiella africana. …”
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Alpha-defensins increase NTHi binding but not engulfment by the macrophages enhancing airway inflammation in Alpha-1 antitrypsin deficiency by Jungnam Lee, Naweed Mohammad, Kyudong Han, Kyudong Han, Tammy Flagg-Dowie, Maria Magallon, Mark L. Brantly, Karina A. Serban, Karina A. Serban

“…Despite the antimicrobial activities of α-defensins by direct bacterial killing and by modulation of immune responses, AATD individuals are paradoxically burdened by recurrent exacerbation triggered by bacterial infections, frequently with nontypeable Haemophilus influenzae (NTHi). Previous studies demonstrated that high, rather than low α-defensin level could modulate the local pro-inflammatory milieu of bronchial epithelial cells and macrophages promoting chronic inflammation and lower pathogen phagocytosis. …”
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A study on Bacterial Infections Associated with Central Nervous System in Pakistani Population by Muneeba Afzal, Hamza Altaf, Tayyaba Faiz, Samra Mannan

“…Major pathogens included Streptococcus pneumoniae, Acinetobacter baumannii, Enterobacter cloacae, Enterococcus faecium, and Haemophilus influenzae, Viruses, fungi, and parasites were also involved. …”
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Mesenchymal Stem Cells Enhance Pulmonary Antimicrobial Immunity and Prevent Following Bacterial Infection by Wenchao Li, Weiwei Chen, Saisai Huang, Xiaojun Tang, Genhong Yao, Lingyun Sun

“…To investigate the influence of CTX and MSCs on the immune defence against infection, the treated mice were intranasally infected with opportunistic pathogen Haemophilus influenzae (Hi). Bacterial clearance and antibacterial immune responses were analysed. …”
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Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter by Parveen Goyal, KanagaVijayan Dhanabalan, Mariafrancesca Scalise, Rosmarie Friemann, Cesare Indiveri, Renwick CJ Dobson, Kutti R Vinothkumar, Subramanian Ramaswamy

“…We have previously reported the structures of SiaQM, a membrane-embedded component of the Haemophilus influenzae TRAP transport system, (Currie et al., 2024). …”
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Signatures of lower respiratory tract microbiome in children with severe community-acquired pneumonia using shotgun metagenomic sequencing by Ting-Yu Yen, Ching Hsu, Ni-Chung Lee, Chao-Szu Wu, Hsin Wang, Kuan-Yi Lee, Chia-Ray Lin, Chun-Yi Lu, Mo-Li Tsai, Tzu-Yu Liu, Che Lin, Chien-Yu Chen, Luan-Yin Chang, Feipei Lai, Li-Min Huang

“…The results showed that Haemophilus influenzae was more prominent in children who were critical, accompanied with increased expression of intracellular transport, secretion, and vesicle transport genes. …”
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Bacterial profile and antibiotic susceptibility pattern of adult lower respiratory tract infections in Colombo, Sri Lanka by Nadeesha Amarasinghe, Muthulingam Athavan, Deepal Jayamanne, Yamuna Rajapakshe, Aflah Sadikeen, Kirthi Gunasekara, Amitha Fernando, Lilani Karunanayake

“…Coliforms (n = 176, 43.6%), and Pseudomonas aeruginosa (n = 117, 29%) were the most common isolated bacteria, followed by Moraxella (n = 47, 11.6%), Haemophilus influenzae (n = 23, 5.7%), and Streptococcus pneumoniae (n = 18, 4.4%). …”
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Alleviating symptoms of paediatric acute rhinosinusitis and acute otitis media with otorrhea using nasal-spraying Bacillus probiotics: a randomized controlled trial by Thanh Huu Khieu, Dung Phuong Le, Binh Thanh Nguyen, Binh Thanh Ngo, Hong Thi Chu, Duc Minh Truong, Hung Minh Nguyen, Anh Hoa Nguyen, Tung Dinh Pham, Anh Thi Van Nguyen

“…By day 3, compared to day 0, the Navax group exhibited > 1200-fold reduction in Streptococcus pneumoniae and ≥ 4-fold reduction in Haemophilus influenzae concentrations (p < 0.05) in both nasopharyngeal and middle ear fluid samples, whereas the Control group showed no significant reductions. …”
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Association of gross domestic product with equitable access to childhood vaccines in 195 countries: a systematic review and meta-analysis by Kwabena Obeng Duedu, Yakhya Dieye, Andreas Ateke Njoh, Jerome Nyhalah Dinga, Jones Soladoye Akinbobola, Funmilayo Ibitayo Deborah Afolayan, Tesfaye Kassa, David Dazhia Lazarus, Gezahegne Mamo Kassa, Nefefe Tshifhiwa, Mustapha Oumouna

“…Global vaccination coverage for tuberculosis, diphtheria/tetanus/pertussis, hepatitis B, Haemophilus influenzae type b, measles, polio, meningitis and HPV had a significantly higher coverage than COVID-19. …”
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Retrospective cross-sectional study on bronchiectasis in adult Aboriginal Australians: disease characteristics and comparison with ethnically diverse global bronchiectasis registry... by Timothy Howarth, Subash Heraganahally, Claire Gibbs, Lata Jayaram, Asanga Abeyaratne, Shiidheshwar J Ravichandran, Davaadorj Erdenebayar, Winnie Chen, Hubertus Jersmann

“…Sputum microbiology showed Haemophilus influenzae (57%) isolated at 3.4 to 6 times the rate of other registry cohorts and Pseudomonas aeruginosa in 31%. …”
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The Spectrum of Pulmonary Disease in Patients with HIV Infection by Julio Sg Montaner, Leila Spour, Carlos Zala

“…Mycobacterium tuberculosis infection and pyogenic bacterial pneumonia secondary to Streptococcus pneumoniae. Haemophilus influenzae or Staphylococcus aureus. Among the noninfectious causes of pulmonary disease. the most common are Kaposi's sarcoma. airways hyper-reactive disease (asthma) and emphysema. …”
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One-step diagnosis of infection and lung cancer using metagenomic sequencing by Shaoqiang Li, Yangqing Zhan, Yan Wang, Weilong Li, Xidong Wang, Haoru Wang, Wenjun Sun, Xuefang Cao, Zhengtu Li, Feng Ye

“…Furthermore, Haemophilus influenzae was enriched in the early-stage SCC group and significantly associated with CRP values. …”
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