Delivery of dendritic cells targeting 3M2e-HA2 nanoparticles with a CpG adjuvant via lysosomal escape of Salmonella enhances protection against H9N2 avian influenza virus by Futing Jia, Wenfeng Wang, Yawen Tian, Ainul Zahra, Yingkai He, Chongbo Ge, Tongyu Zhang, Mingyue Wang, Jingshuo Gong, Gerui Zhang, Guilian Yang, Wentao Yang, Chunwei Shi, Jianzhong Wang, Haibin Huang, Xin Cao, Yang Zeng, Nan Wang, Zhannan Wang, Chunfeng Wang, Yanlong Jiang

Subjects: “…H9N2 influenza virus…”
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The PB1 protein of H9N2 influenza A virus inhibits antiviral innate immunity by targeting MAVS for TRIM25-mediated autophagic degradationThe parent data and images support the findings of this work freely available at by Jiawei Luo, Yiyuan Lu, Enqi Dai, Nianchun Yin, Ting Wang, Hongxi Qian, Qingrong Jiang, Xin Cao, Chunfeng Wang, Yan Zeng

“…The proteins encoded by Influenza A virus (IAV) evade the innate immune system through diverse strategies to facilitate their replication. …”
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Single Dose of Attenuated Vaccinia Viruses Expressing H5 Hemagglutinin Affords Rapid and Long-Term Protection Against Lethal Infection with Highly Pathogenic Avian Influenza A H5N1 Virus in Mice and Monkeys by Fumihiko Yasui, Keisuke Munekata, Tomoko Fujiyuki, Takeshi Kuraishi, Kenzaburo Yamaji, Tomoko Honda, Sumiko Gomi, Misako Yoneda, Takahiro Sanada, Koji Ishii, Yoshihiro Sakoda, Hiroshi Kida, Shosaku Hattori, Chieko Kai, Michinori Kohara

“…Background/Objectives: In preparation for a potential pandemic caused by the H5N1 highly pathogenic avian influenza (HPAI) virus, pre-pandemic vaccines against several viral clades have been developed and stocked worldwide. …”
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Estimating the reproduction number from the initial phase of the Spanish flu pandemic waves in Geneva, Switzerland by Gerardo Chowell, Catherine E. Ammon, Nicolas W. Hengartner, James M. Hyman

Subjects: “…spanish flu; 1918 influenza pandemic; reproduction number;boot- strapping; nonlinear curve fitting; uncertaintyquantification; geneva; switzerland.…”
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Spray vaccination with a safe and bivalent H9N2 recombinant chimeric NDV vector vaccine elicits complete protection against NDV and H9N2 AIV challenge by Xiaoquan Wang, Jing Dai, Wenhao Yang, Yao Yao, Jin Zhang, Kaituo Liu, Xiaolong Lu, Ruyi Gao, Yu Chen, Jiao Hu, Min Gu, Shunlin Hu, Xiufan Liu, Xiaowen Liu

Subjects: “…H9N2 subtype avian influenza virus…”
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Real World Evaluation of Next-Day Molecular Respiratory Infectious Disease Testing on Healthcare Resource Utilization and Costs by French AJ, Fragala MS, Evans AS, Upadhyay P, Goldberg SE, Reddy J

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Evaluation of NxTAG Respiratory Pathogen Panel and Comparison with xTAG Respiratory Viral Panel Fast v2 and Film Array Respiratory Panel for Detecting Respiratory Pathogens in Nasopharyngeal Aspirates and Swine/Avian-Origin Influenza A Subtypes in Culture Isolates by K. H. Chan, K. K. W. To, P. T. W. Li, T. L. Wong, R. Zhang, K. K. H. Chik, G. Chan, C. C. Y. Yip, H. L. Chen, I. F. N. Hung, J. F. W. Chan, K. Y. Yuen

“…All three multiplex assays correctly typed and genotyped the influenza viruses, except for NxTAG RRP that could not distinguish H3N2 from H3N2v. …”
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Corrigendum to “Influenza and the risk of active tuberculosis occurrence among individuals with latent tuberculosis infection: A national cohort study in South Korea (2015–2020)” [J Microbiol Immunol Infect 57 (2024) 437–445 JOUMII-D-23-00515R1] by Jaehee Lee, Hyewon Seo, Dohyang Kim, Jinseub Hwang, Jin-Won Kwon

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The Saudi thoracic society guidelines for vaccinations in adult patients with chronic respiratory diseases by Mohammed Al Ghobain, Fayssal Farahat, Mohammed Zeitouni, Waleed Alsowayan, Sultan Al-Awfi, Ali AlBarrak, Shareefah Al-Basheri, Fatmah Alhabeeb, Esam H. Alhamad

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Viral Etiology of Chronic Obstructive Pulmonary Disease Exacerbations during the A/H1N1pdm09 Pandemic and Postpandemic Period by Ivan Sanz, Sonia Tamames, Silvia Rojo, Mar Justel, José Eugenio Lozano, Carlos Disdier, Tomás Vega, Raúl Ortiz de Lejarazu

“…Emergence of A/H1N1pdm influenza virus in the 2009 pandemic changed the viral etiology of exacerbations that were reported before the pandemic. …”
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Ode to Oseltamivir and Amantadine? by JM Conly, BL Johnston

“…Influenza A and B viruses are the two major types of influenza viruses that cause human epidemic disease. …”
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Development of Primer Panels for Whole-Genome Amplification and Sequencing of Human Seasonal Coronaviruses: hCoV-OC43, hCoV-HKU1, hCoV-229E, and hCoV-NL63 by Tamila Musaeva, Artem Fadeev, Maria Pisareva, Veronika Eder, Andrey Ksenafontov, Margarita Korzhanova, Valery Tsvetkov, Alexander Perederiy, Irina Kiseleva, Daria Danilenko, Dmitry Lioznov, Andrey Komissarov

“…The panel was validated using nasopharyngeal swab samples collected within the Global Influenza Hospital Surveillance Network (GIHSN) project. …”
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Postinfluenza Vaccination Idiopathic Thrombocytopenic Purpura in Three Elderly Patients by Joji Nagasaki, Masahiro Manabe, Kentaro Ido, Hiroyoshi Ichihara, Yasutaka Aoyama, Tadanobu Ohta, Yoshio Furukawa, Atsuko Mugitani

“…We report the cases of three elderly patients who developed ITP after receiving influenza vaccinations. The platelet count of an 81-year-old woman fell to 27,000/μL after she received an influenza vaccination. …”
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Development and evaluation of a recombinant monoclonal human antibody with virus-neutralizing activity against the F glycoprotein of respiratory syncytial virus by Sergey A. Klotchenko, Ekaterina A. Romanovskaya-Romanko, Marina A. Plotnikova, Anastasia A. Pulkina, Aram A. Shaldzhyan, Dmitry S. Balabashin, Victoria A. Toporova, Teimur K. Aliev, Natalia E. Gyulikhandanova, Dmitry A. Lioznov

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Prevalence and Genetic Characteristics of Human Bocaviruses Detected in Patients with Acute Respiratory Infections in Bulgaria by Neli Korsun, Svetla Angelova, Ivelina Trifonova, Silvia Voleva, Iliana Grigorova, Iren Tzotcheva, Sirma Mileva, Penka Perenovska

“…HBoV was identified in 98 (5.3%) patients and was the 6th most prevalent virus after respiratory-syncytial virus (20.4%), influenza A(H1N1)pdm09 (11.1%), A(H3N2) (10.5%), rhinoviruses (9.9%), and adenoviruses (6.8%). …”
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Fatal H1N1-Related Acute Necrotizing Encephalopathy in an Adult by Yu-Jin Lee, D. Scott Smith, Vivek A. Rao, Robert D. Siegel, Jon Kosek, Carol A. Glaser, Alexander C. Flint

“…Acute necrotizing encephalopathy (ANE) is a severe neurological complication of influenza infection, including H1N1 influenza. Many cases of ANE have been reported in the pediatric literature, but very few cases have been described in adults. …”
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Disease Association and Diagnosis of Human Herpesvirus 6 by JM Weber, GAR Wilson

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Planning for the Pandemic by Joanne Embree

“…Will it have the same transmission characteristics as the yearly endemic influenza strains or will it be so different that our routine infection prevention precautions for influenza will be ineffective? …”
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Association of outpatient use of renin–angiotensin–aldosterone system blockers on outcomes of acute respiratory illness during the COVID-19 pandemic: a cohort study by Molly Moore Jeffery, Lucas Oliveira J e Silva, Fernanda Bellolio, Nathan W Cummins, Timothy M Dempsey, Vesna D Garovic, Andrew Limper

“…Objectives Evaluate the associations between patients taking ACE inhibitors and angiotensin receptor blockers (ARBs) and their clinical outcomes after an acute viral respiratory illness (AVRI) due to COVID-19.Design Retrospective cohort.Setting The USA; 2017–2018 influenza season, 2018–2019 influenza season, and 2019–2020 influenza/COVID-19 season.Participants People with hypertension (HTN) taking an ACEi, ARB or other HTN medications, and experiencing AVRI.Main outcome measures Change in hospital admission, intensive care unit (ICU) or coronary care unit (CCU), acute respiratory distress (ARD), ARD syndrome (ARDS) and all-cause mortality, comparing COVID-19 to pre-COVID-19 influenza seasons.Results The cohort included 1 059 474 episodes of AVRI (653 797 filled an ACEi or ARB, and 405 677 other HTN medications). 58.6% were women and 72.9% with age ≥65. …”
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SARS-CoV-2 infection rates and associated risk factors in healthcare workers: systematic review and meta-analysis by Amit Bansal, Mai-Chi Trieu, Emily M. Eriksson, Fan Zhou, Jodie McVernon, Karl Albert Brokstad, Rebecca Jane Cox

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