Racial disparities in extended venous thromboembolism prophylaxis after hysterectomy. by Wenbo Wu, Sherry Wu, Sim Berlene Mariano, Richard E Burney, Jonathan P Kuriakose

“…Descriptive statistics and mixed effects logistic regression were performed for risk adjustment with covariates such as age, cancer occurrence, inflammatory bowel disease, American Society of Anesthesiologists physical status classification, perioperative VTE prophylaxis, postoperative VTE prophylaxis, surgical approach, and surgical duration, among other variables.…”
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The Stability-Indicating Ultra High-Performance Liquid Chromatography with Diode Array Detector and Tandem Mass Spectrometry Method Applied for the Forced Degradation Study of Ritl... by Jelena Kovačić, Daniela Amidžić Klarić, Nikša Turk, Željko Krznarić, Emma Riordan, Ana Mornar

“…Background/Objectives: Janus kinase inhibitors open new horizons for small-molecule drugs in treating inflammatory bowel disease, with ritlecitinib demonstrating significant efficacy in clinical trials for ulcerative colitis and Crohn’s disease. …”
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Clinical Efficacy of Probiotic Therapy on Bowel-Related Symptoms in Patients with Ulcerative Colitis during Endoscopic Remission: An Observational Study by Jin Lee, Su Bum Park, Hyung Wook Kim, Hong Sub Lee, Sam Ryong Jee, Jong Hun Lee, Tae Oh Kim

“…All patients completed bowel-related symptom questionnaires and short inflammatory bowel disease questionnaires (SIBDQs) at the start and end of the 4-week treatment period. …”
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A nested case-control study evaluating the relationship between adverse childhood experiences and immune-mediated inflammatory disease in the Canadian Longitudinal Study on Aging by Charles N Bernstein, Ruth Ann Marrie, Julia O'Mahony

“…We evaluated whether the association of ACE with disease differs between IMID and other chronic diseases.Design Nested retrospective case-control study.Setting We used data from the Canadian Longitudinal Study on Aging (CLSA), which recruited participants aged 45–85 years between 2010 and 2015.Participants We included 12 627 CLSA participants: 2 102 who reported diagnoses of IMID (258 multiple sclerosis (MS), 1 692 rheumatoid arthritis (RA) and 160 inflammatory bowel disease (IBD)), 5 519 with diabetes, 170 with epilepsy, 3 889 with asthma and 1 125 with no chronic diseases. …”
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Cucurbitacin IIa Alleviates Colitis via Promoting the Release of Host-Derived Extracellular Vesicles Encapsulating microRNA-30b-5p by Zhao Y, Jiang B, Zuo S

“…In conclusion, cucurbitacin IIa appears to alleviate colitis by promoting the release of microRNA-30b-5p from host-derived extracellular vesicles.Conclusion: These findings enhance our understanding of cucurbitacin IIa’s effects on intestinal health and offer potential new therapeutic targets for inflammatory bowel disease treatment.Keywords: colitis, cucurbitacins, extracellular vesicles, inflammation, microRNA…”
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Extra-Articular Symptoms in Constellation with Selected Serum Cytokines and Disease Activity in Spondyloarthritis by Hanna Przepiera-Będzak, Katarzyna Fischer, Marek Brzosko

“…Patients with inflammatory bowel disease (IBD) had higher VAS (P=0.03), CRP (P=0.0009), and IL-6 (P=0.0003) levels. …”
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Diagnostic Value of Fecal Calprotectin (S100 A8/A9) Test in Children with Chronic Abdominal Pain by Stanisław Pieczarkowski, Kinga Kowalska-Duplaga, Przemko Kwinta, Przemysław Tomasik, Andrzej Wędrychowicz, Krzysztof Fyderek

“…The aim of the study was to establish whether fecal calprotectin concentration (FCC) may be useful in children with chronic abdominal pain to differentiate between inflammatory bowel disease (IBD), other inflammatory gastrointestinal disorders, and functional gastrointestinal disorders. …”
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Mucosal Epithelial Jak Kinases in Health and Diseases by Narendra Kumar, Longxiang Kuang, Ryan Villa, Priyam Kumar, Jayshree Mishra

“…As information about the roles of Jak3 in gastrointestinal functions and associated diseases are only just emerging, in the review, we summarize its implications in gastrointestinal wound repair, inflammatory bowel disease, obesity-associated metabolic syndrome, and epithelial cancers. …”
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Role of the Kaiso gene in the development of inflammation in Mucin-2 defcient mice by E. A. Litvinova, K. M. Achasova, M. A. Borisova, S. V. Zhenilo, E. B. Prokhortchouk, E. N. Kozhevnikova

“…The number of people with inflammatory bowel disease (IBD) is constantly increasing worldwide. …”
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Serum Cytokine Profiles in Children with Crohn’s Disease by Ekaterina Vasilyeva, Sayar Abdulkhakov, Georgi Cherepnev, Ekaterina Martynova, Irina Mayanskaya, Alina Valeeva, Rustam Abdulkhakov, Dilyara Safina, Svetlana Khaiboullina, Albert Rizvanov

“…Crohn’s disease (CD) is a chronic inflammatory bowel disease that can be diagnosed at any age. …”
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Tumour necrosis factor inhibitors in Ulcerative colitis: real-world data on Therapeutic drug monitoring and evaluation of current treatment targets (STRIDE II) by Jonas Andre Lundekvam, Marte Lie Høivik, Karoline Anisdahl, Milada Cvancarova Småstuen, David J. Warren, Nils Bolstad, Asle Wilhelm Medhus

“…Background The benefit of therapeutic drug monitoring (TDM) and implementation of recommendations from the Selection of Therapeutic Targets in Inflammatory Bowel Disease (IBD, STRIDE) are discussed in the IBD community. …”
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Safety and Efficacy of Exclusive Enteral Nutrition for Percutaneously Undrainable Abdominal Abscesses in Crohn’s Disease by Yibin Zhu, Liang Xu, Wei Liu, Weilin Qi, Qian Cao, Wei Zhou

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Mast Cells Exert Anti-Inflammatory Effects in an IL10−/− Model of Spontaneous Colitis by E. M. Lennon, L. B. Borst, L. L. Edwards, A. J. Moeser

“…Mast cells are well established as divergent modulators of inflammation and immunosuppression, but their role in inflammatory bowel disease (IBD) remains to be fully defined. …”
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Laparoscopy Combined with Enhanced Recovery Pathway in Ileocecal Resection for Crohn’s Disease: A Randomized Study by Yibin Zhu, Jianjian Xiang, Wei Liu, Qian Cao, Wei Zhou

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New-onset gastrointestinal disorders in COVID-19 patients 3.5 years post-infection in the inner-city population in the Bronx by Sagar Changela, Samad Ashraf, Justin Y. Lu, Kevin E. Duong, Sonya Henry, Stephen H. Wang, Tim Q. Duong

“…The primary outcome was new GID which included peptic ulcer, inflammatory bowel disease, irritable bowel syndrome, diverticulosis, diverticulitis, and biliary disease. …”
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SMAD4 Protein Expression Is Downregulated in Ileal Epithelial Cells from Patients with Crohn’s Disease with Significant Inverse Correlation to Disease Activity by Pia Klausen, John Gásdal Karstensen, Mehmet Coskun, Adrian Săftoiu, Peter Vilmann, Jack Bernard Cowland, Lene Buhl Riis

“…Small mothers against decapentaplegic (SMAD)4 and SMAD7 are key regulatory components in the immunosuppressive transforming growth factor- (TGF-) β signaling pathway, which is defective in inflammatory bowel disease (IBD). SMAD4 may play an important role in the pathogenesis of IBD as indicated in experimental models of colitis. …”
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Real-world assessment of effectiveness and safety of filgotinib in 286 patients with ulcerative colitis in 9 UK centres by David Young, Sohail Rahmany, Deborah Taylor, Emma Davis, Michael Colwill, Sonia Kalyanji Mehta, Roisin Campbell, Karl Hazel, Karishma Sethi-Arora, Susan Ritchie, Ashley I Heinson, Helen Moyses, Keith Bodger, Emma Johnston, Lucy Hicks, Anjan Dhar, Jimmy Limdi, Rachel Cooney, John Paul Seenan, Kamal Patel, Alissa Walsh, Fraser Cummings

“…Methods: A retrospective observational cohort evaluation was conducted across nine UK inflammatory bowel disease centres. Baseline demographic and clinical data, clinical disease activity scores, endoscopic activity indices, and biomarkers (C-reactive protein and faecal calprotectin) were collected at baseline, at 8–12 weeks after initiation (post-induction) and during maintenance (the most recent review) where available. …”
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Lactobacillus from fermented bamboo shoots prevents inflammation in DSS-induced colitis mice via modulating gut microbiome and serum metabolites by Xiangru Liu, Xiaoling Lu, Hao Nie, Jing Yan, Zhiwen Ma, Hailin Li, Shixin Tang, Qi Yin, Jingfu Qiu

“…However, the probiotic potential of Lactobacillus derived from FBS reminds largely unexplored, especially for diseases with a low prevalence in areas consuming FBS, namely, inflammatory bowel disease. In this study, Lactiplantibacillus pentosus YQ001 and Lentilactobacillus senioris YQ005 were screening by in vitro probiotic tests to further investigate the probioticlike bioactivity in dextran sulfate sodium (DSS)-induced ulcerative colitis (UC) mouse. …”
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Interrelationships of the Intestinal Microbiome, Trimethylamine N-Oxide and Lipopolysaccharide-Binding Protein with Crohn’s Disease Activity by Yelena Laryushina, Nadezhda Samoilova-Bedych, Lyudmila Turgunova, Alexandr Marchenko, Yermek Turgunov, Samat Kozhakhmetov, Maxat Suieubayev, Nurislam Mukhanbetzhanov, Nadezhda Kabdulina

“…Crohn’s disease (CD) is a multifactorial inflammatory bowel disease whose pathogenetic mechanisms are a field of ongoing study. …”
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β-Catenin Regulation in Sporadic Colorectal Carcinogenesis: Not as Simple as APC by Ernst Fredericks, Gill Dealtry, Saartjie Roux

“…Using qPCR and IHC, we compared β-catenin, PPARγ, COX-2, and IL-17A in the colonic mucosa of patients with sporadic CRC, inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS), against a normal control population. …”
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