IL-32: A Novel Pluripotent Inflammatory Interleukin, towards Gastric Inflammation, Gastric Cancer, and Chronic Rhino Sinusitis by Muhammad Babar Khawar, Muddasir Hassan Abbasi, Nadeem Sheikh

“…It was found to induce the expression of various inflammatory cytokines including TNF-α, IL-6, and IL-1β as well as macrophage inflammatory protein-2 (MIP-2) and has been reported previously to be involved in the pathogenesis and progression of a number of inflammatory disorders, namely, inflammatory bowel disease (IBD), gastric inflammation and cancer, rheumatoid arthritis, and chronic obstructive pulmonary disease (COPD). …”
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Taurine prevents mitochondrial dysfunction and protects mitochondria from reactive oxygen species and deuterium toxicity by Stephanie Seneff, Anthony M. Kyriakopoulos

“…We describe how taurine could potentially alleviate deuterium stress, primarily through metabolic collaboration among various gut microflora to produce deuterium depleted nutrients and deuterium depleted water, and in this way protect against leaky gut barrier, inflammatory bowel disease, and colon cancer.…”
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GrB-Fc-KS49, an anti-EMP2 granzyme B fusion protein therapeutic alters immune cell infiltration and suppresses breast cancer growth by Ana Alvarez de Cienfuegos, Lawrence H Cheung, Khalid A Mohamedali, Michael G Rosenblum, Brian Aguirre, Cheng-Hsiang Lu, Anubhav Chandla, Nidhi Kejriwal, Lucia Liu, Ann M Chan, SuYin Kok, Sergio Duarte, David Casero, Madhuri Wadehra

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Laparoscopic Surgery for Recurrent Crohn's Disease by Antonino Spinelli, Matteo Sacchi, Piero Bazzi, Nicoletta Leone, Silvio Danese, Marco Montorsi

“…Laparoscopy experienced a slower diffusion in inflammatory bowel disease surgery than in oncologic colorectal surgery, but proved to be safe and effective, and is currently considered the gold standard for the treatment of primary uncomplicated ileocolic CD. …”
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Microfluidic organ-on-chip systems for periodontal research: advances and future directions by Gopu Sriram, Gopu Sriram, Hardik Makkar, Hardik Makkar

“…The pathogenesis of periodontal disease involves a complex interplay between microbial dysbiosis and host immune responses, which can lead to a loss of dental support structures and contribute to systemic conditions such as cardiovascular disease, diabetes, and inflammatory bowel disease. This provides a comprehensive overview of the latest developments in millifluidic and microfluidic systems designed to emulate periodontal host-microbe and host-material interactions. …”
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Biodegradable and Stimuli-Responsive Nanomaterials for Targeted Drug Delivery in Autoimmune Diseases by Nargish Parvin, Sang Woo Joo, Tapas K. Mandal

“…We discuss the underlying mechanisms of stimuli-responsive nanomaterials, recent applications in treating diseases such as rheumatoid arthritis, multiple sclerosis, and inflammatory bowel disease, and the design considerations essential for clinical translation. …”
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Unraveling the microbial mysteries: gut microbiota’s role in ulcerative colitis by Keyu Ren, Chunming Yong, Yanchun Jin, Shanwei Rong, Kuijin Xue, Bin Cao, Hongyun Wei

“…Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by persistent inflammation of the colon. …”
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CONDITIONS OF SKIN AND INTESTINE MICROBIOTES IN PATIENTS WITH PSORIASIS by Ya.O. Yemchenko, K.E. Ishcheikin, I.P. Kaidashev, G.Yu. Morokhovets

“…Changes in the intestinal microbiome in psoriasis are similar to those observed in patients with inflammatory bowel disease. Changes in the microbiome associated with psoriasis can induce an inflammatory response by activating the cytokines IL-23, IL-17 and IL-22, as well as modulating gamma-interferon and inhibiting the production of T-regulatory cells. …”
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Immune Thrombocytopenic Purpura (ITP) as an Uncommon Extraintestinal Complication of Crohn’s Disease: Case Vignette and Systematic Literature Review by Raisa Epistola, Tiffanie Do, Ritika Vankina, Daniel Wu, James Yeh, Michael W. Fleischman, Jennifer M. Lee

“…While the association of immune thrombocytopenic purpura (ITP) and inflammatory bowel disease (IBD) has been described in a few case reports, management of ITP as an extraintestinal manifestation of Crohn’s disease (CD) is less studied. …”
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PD-1 Inhibitor Therapy in a Patient with Preexisting P-ANCA Vasculitis: A Case Report and Review of the Literature by Amanda Ramos, Marcela del Carmen, Oladapo Yeku

“…A review of the scientific literature reveals several cases of the successful use of immune checkpoint inhibitors in patients with autoimmune diseases, including systemic lupus erythematosus, rheumatoid arthritis, and inflammatory bowel disease. Conclusion. This is one of the first reports of a patient with an underlying autoimmune vasculitis successfully treated with an immune checkpoint inhibitor without exacerbating her underlying autoimmune condition. …”
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Capsule Endoscopy for Crohn’s Disease: Current Status of Diagnosis and Management by Dong-Hoon Yang, Bora Keum, Yoon Tae Jeen

“…Crohn’s disease (CD) is an idiopathic inflammatory bowel disease involving the small and/or large intestine. …”
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Leclercia adecarboxylata Bacteremia in a Patient with Ulcerative Colitis by Amir Kashani, Morteza Chitsazan, Kendrick Che, Roger C. Garrison

“…Patients with inflammatory bowel disease (IBD) are a high risk population for bacteremia. …”
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Sevelamer Carbonate Crystal-Induced Colitis by T. Lai, A. Frugoli, B. Barrows, M. Salehpour

“…Colonoscopy demonstrated nearly obstructing lesions worrisome for colonic ischemia or inflammatory bowel disease. Pathological review of histology demonstrated ragged colonic mucosa with ulcerative debris and nonpolarizing crystalline material at the sites of ulceration, morphologically consistent with the phosphate binder, sevelamer carbonate. …”
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Differential Intestinal Mucosa Transcriptomic Biomarkers for Crohn’s Disease and Ulcerative Colitis by Maria Dobre, Elena Milanesi, Teodora Ecaterina Mănuc, Dorel Eugen Arsene, Cristian George Ţieranu, Carlo Maj, Gabriel Becheanu, Mircea Mănuc

“…Genetic research has shaped the inflammatory bowel disease (IBD) landscape identifying nearly two hundred risk loci. …”
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Comparison of Vitamin D Levels in Patients with Chronic Lymphocytic Thyroiditis and the Normal Population, and Role of Vitamin D on Autoimmunity by Serkan Yıldırım

“…Purpose It is known that vitamin D deficiency has a role in the formation of autoimmune diseases, inflammatory bowel disease, rheumatoid arthritis, multiple sclerosis, diabetes, many types of cancer and heart diseases. …”
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Helminth Parasites and the Modulation of Joint Inflammation by Chelsea E. Matisz, Jason J. McDougall, Keith A. Sharkey, Derek M. McKay

“…Indeed, infection with helminth parasites has been tried as a therapy in inflammatory bowel disease, and there are case reports relating to other conditions (e.g., autism); however, the impact of infection with parasitic helminths on musculoskeletal diseases has not been extensively studied. …”
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Preventive Effect of TU-100 on a Type-2 Model of Colitis in Mice: Possible Involvement of Enhancing Adrenomedullin in Intestinal Epithelial Cells by Atsushi Kaneko, Toru Kono, Naoko Miura, Naoko Tsuchiya, Masahiro Yamamoto

“…Crohn's disease (CD) and ulcerative colitis (UC), the two major forms of inflammatory bowel disease (IBD), have histopathologically and immunologically different characteristics. …”
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Common variable immunodeficiency: An uncommon cause of bronchiectasis, granulomatous disease, chronic liver disease, and enteropathy – Case report and review of literature by Veena Shamsudeen, Arun Hegde, Uday Bhanu Kovilapu, Nisha Verma, Anurag Jain

“…Gastrointestinal involvement may manifest either in the form of an infectious diarrhea due to parasites such as Giardia lamblia and bacteria such as Campylobacter jejuni, or as a noninfectious enteropathy resembling coeliac disease or inflammatory bowel disease. Some patients develop a granulomatous disease manifesting with noncaseating granulomas, especially of lymph nodes, skin, lung, spleen, and liver. …”
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Difficulties the Conservative Treatment of Crohn’s Disease Complicated by Autoimmune Hemophilia A by E. L. Belyaeva, O. I. Filippova, A. V. Koloskov, A. A. Naydenov, F. D. Albegova

“…When acquired coagulopathy develops in a patient with bleeding against the background of an inflammatory bowel disease, it aggravates the course of the disease and worsens the prognosis.…”
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Synthesis of Arginase Inhibitors: An Overview by Maria Cristina Molaro, Chiara Battisegola, Marica Erminia Schiano, Mariacristina Failla, Maria Grazia Rimoli, Loretta Lazzarato, Konstantin Chegaev, Federica Sodano

“…In recent decades, the abnormal expression of ARG-1 or ARG-2 has been reported to be increasingly linked to a variety of diseases, including cardiovascular disease, inflammatory bowel disease, Alzheimer’s disease, and cancer. …”
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